IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice

Journal of Clinical Investigation

Volumn 117, Issue 12, 2007, Pages 3786-3799

  Gasse, Pamela ^a   Mary, Caroline ^a   Guenon, Isabelle ^b   Noulin, Nicolas ^a,c   Charron, Sabine ^a   Schnyder Candrian, Silvia ^a   Schnyder, Bruno ^a   Akira, Shizuo ^d   Quesniaux, Valérie F J ^a   Lagente, Vincent ^b   Ryffel, Bernhard ^a   Couillin, Isabelle ^a,e  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c Key Obs SA   (France)

^d OSAKA UNIVERSITY   (Japan)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR 1; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN 1BETA; MYELOID DIFFERENTIATION FACTOR 88; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG INHIBITION; LUNG FIBROSIS; LYMPHOCYTE ACTIVATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; BONE MARROW TRANSPLANTATION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; INTERLEUKIN-8; LYMPHOKINES; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; PNEUMONIA; PULMONARY FIBROSIS; RECEPTORS, INTERLEUKIN-1 TYPE I; RECOMBINANT PROTEINS; RESPIRATORY DISTRESS SYNDROME, ADULT; SIALOGLYCOPROTEINS; SIGNAL TRANSDUCTION; TRANSPLANTATION CHIMERA;

EID: 36849056773     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI32285     Document Type: Article

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