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Volumn 59, Issue 6, 2011, Pages 759-769

Tiny non-coding RNAs in Parkinson's disease: Implications, expectations and hypes

Author keywords

Micro RNA; Parkinson's disease; Small interfering RNA; Tiny non coding RNAs

Indexed keywords

ALPHA SYNUCLEIN; LEUCINE RICH REPEAT KINASE 2; MICRORNA; PLASMID DNA; SMALL INTERFERING RNA; TYROSINE 3 MONOOXYGENASE;

EID: 80053171864     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.07.009     Document Type: Short Survey
Times cited : (9)

References (146)
  • 1
    • 15044354554 scopus 로고    scopus 로고
    • RNAi-induced gene silencing by local electroporation in targeting brain region
    • DOI 10.1152/jn.00161.2004
    • Y. Akaneya, B. Jiang, and T. Tsumoto RNAi-induced gene silencing by local electroporation in targeting brain region J. Neurophysiol. 93 2005 594 602 (Pubitemid 40626864)
    • (2005) Journal of Neurophysiology , vol.93 , Issue.1 , pp. 594-602
    • Akaneya, Y.1    Jiang, B.2    Tsumoto, T.3
  • 2
    • 4043165474 scopus 로고    scopus 로고
    • Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons
    • DOI 10.1242/dev.01128
    • L. Alberi, P. Sgado, and H.H. Simon Engrailed genes are cell-autonomously required to prevent apoptosis in the mesencephalic dopaminergic neurons Development 131 2004 3229 3236 (Pubitemid 39077445)
    • (2004) Development , vol.131 , Issue.13 , pp. 3229-3236
    • Alberi, L.1    Sgado, P.2    Simon, H.H.3
  • 3
    • 70349991886 scopus 로고    scopus 로고
    • LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
    • J. Alegre-Abarrategui, H. Christian, M.M. Lufino, R. Mutihac, L.L. Venda, O. Ansorge, and R. Wade-Martins LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model Hum. Mol. Genet. 18 2009 4022 4034
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 4022-4034
    • Alegre-Abarrategui, J.1    Christian, H.2    Lufino, M.M.3    Mutihac, R.4    Venda, L.L.5    Ansorge, O.6    Wade-Martins, R.7
  • 6
    • 0022616537 scopus 로고
    • Substance P and Parkinson's disease: A causal relationship?
    • R. Barker Substance P and Parkinson's disease: a causal relationship? J. Theor. Biol. 120 1986 353 362 (Pubitemid 16099218)
    • (1986) Journal of Theoretical Biology , vol.120 , Issue.3 , pp. 353-362
    • Barker, R.1
  • 9
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • DOI 10.1038/35053110
    • E. Bernstein, A.A. Caudy, S.M. Hammond, and G.J. Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409 2001 363 366 (Pubitemid 32151243)
    • (2001) Nature , vol.409 , Issue.6818 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 11
    • 26244460395 scopus 로고    scopus 로고
    • Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease
    • DOI 10.1007/s11064-005-6877-5
    • S.C. Biswas, E. Ryu, C. Park, C. Malagelada, and L.A. Greene Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease Neurochem. Res. 30 2005 839 845 (Pubitemid 41413940)
    • (2005) Neurochemical Research , vol.30 , Issue.6-7 , pp. 839-845
    • Biswas, S.C.1    Ryu, E.2    Park, C.3    Malagelada, C.4    Greene, L.A.5
  • 14
    • 4344566457 scopus 로고    scopus 로고
    • Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system
    • DOI 10.1016/j.ymthe.2004.05.024, PII S1525001604001911
    • C. Burger, O.S. Gorbatyuk, M.J. Velardo, C.S. Peden, P. Williams, S. Zolotukhin, P.J. Reier, R.J. Mandel, and N. Muzyczka Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system Mol. Ther. 10 2004 302 317 (Pubitemid 39117875)
    • (2004) Molecular Therapy , vol.10 , Issue.2 , pp. 302-317
    • Burger, C.1    Gorbatyuk, O.S.2    Velardo, M.J.3    Peden, C.S.4    Williams, P.5    Zolotukhin, S.6    Reier, P.J.7    Mandel, R.J.8    Muzyczka, N.9
  • 15
    • 59849099441 scopus 로고    scopus 로고
    • The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model
    • J. Cai, A. Donaldson, M. Yang, M.S. German, G. Enikolopov, and L. Iacovitti The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model Stem Cells 27 2009 220 229
    • (2009) Stem Cells , vol.27 , pp. 220-229
    • Cai, J.1    Donaldson, A.2    Yang, M.3    German, M.S.4    Enikolopov, G.5    Iacovitti, L.6
  • 16
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of miRNAs and siRNAs
    • R.W. Carthew, and E.J. Sontheimer Origins and mechanisms of miRNAs and siRNAs Cell 136 2009 642 655
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 17
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • D. Castanotto, and J.J. Rossi The promises and pitfalls of RNA-interference-based therapeutics Nature 457 2009 426 433
    • (2009) Nature , vol.457 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2
  • 18
    • 35848947235 scopus 로고    scopus 로고
    • Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: Implications for neurodegeneration and cell death
    • C.T. Chu, J. Zhu, and R. Dagda Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death Autophagy 3 2007 663 666 (Pubitemid 350060074)
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 663-666
    • Chu, C.T.1    Zhu, J.2    Dagda, R.3
  • 19
    • 22244442489 scopus 로고    scopus 로고
    • The biochemistry of Parkinson's disease
    • DOI 10.1146/annurev.biochem.74.082803.133400
    • M.R. Cookson The biochemistry of Parkinson's disease Annu. Rev. Biochem. 74 2005 29 52 (Pubitemid 40995500)
    • (2005) Annual Review of Biochemistry , vol.74 , pp. 29-52
    • Cookson, M.R.1
  • 20
    • 0037320941 scopus 로고    scopus 로고
    • Numerous microRNPs in neuronal cells containing novel microRNAs
    • DOI 10.1261/rna.2141503
    • J. Dostie, Z. Mourelatos, M. Yang, A. Sharma, and G. Dreyfuss Numerous microRNPs in neuronal cells containing novel microRNAs RNA 9 2003 180 186 (Pubitemid 36206286)
    • (2003) RNA , vol.9 , Issue.2 , pp. 180-186
    • Dostie, J.1    Mourelatos, Z.2    Yang, M.3    Sharma, A.4    Dreyfuss, G.5
  • 21
    • 77951249562 scopus 로고    scopus 로고
    • Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153
    • E. Doxakis Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153 J. Biol. Chem. 285 2010 12726 12734
    • (2010) J. Biol. Chem. , vol.285 , pp. 12726-12734
    • Doxakis, E.1
  • 22
    • 28044455435 scopus 로고    scopus 로고
    • MicroPrimer: The biogenesis and function of microRNA
    • DOI 10.1242/dev.02070
    • T. Du, and P.D. Zamore MicroPrimer: the biogenesis and function of microRNA Development 132 2005 4645 4652 (Pubitemid 41685275)
    • (2005) Development , vol.132 , Issue.21 , pp. 4645-4652
    • Du, T.1    Zamore, P.D.2
  • 23
    • 67650267785 scopus 로고    scopus 로고
    • An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity
    • Y. Du, D. Yang, L. Li, G. Luo, T. Li, X. Fan, Q. Wang, X. Zhang, Y. Wang, and W. Le An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity Autophagy 5 2009 663 675
    • (2009) Autophagy , vol.5 , pp. 663-675
    • Du, Y.1    Yang, D.2    Li, L.3    Luo, G.4    Li, T.5    Fan, X.6    Wang, Q.7    Zhang, X.8    Wang, Y.9    Le, W.10
  • 24
    • 55049137165 scopus 로고    scopus 로고
    • MicroRNA biogenesis: There's more than one way to skin a cat
    • M. Faller, and F. Guo MicroRNA biogenesis: there's more than one way to skin a cat Biochim. Biophys. Acta 1779 2008 663 667
    • (2008) Biochim. Biophys. Acta , vol.1779 , pp. 663-667
    • Faller, M.1    Guo, F.2
  • 25
    • 4344648254 scopus 로고    scopus 로고
    • RNA-mediated programming of developmental genome rearrangements in Paramecium tetraurelia
    • DOI 10.1128/MCB.24.17.7370-7379.2004
    • O. Garnier, V. Serrano, S. Duharcourt, and E. Meyer RNA-mediated programming of developmental genome rearrangements in Paramecium tetraurelia Mol. Cell. Biol. 24 2004 7370 7379 (Pubitemid 39121467)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.17 , pp. 7370-7379
    • Garnier, O.1    Serrano, V.2    Duharcourt, S.3    Meyer, E.4
  • 26
    • 61949269129 scopus 로고    scopus 로고
    • Genomic and proteomic biomarkers for Parkinson disease
    • T. Gasser Genomic and proteomic biomarkers for Parkinson disease Neurology 72 2009 S27 S31
    • (2009) Neurology , vol.72
    • Gasser, T.1
  • 27
    • 77955152366 scopus 로고    scopus 로고
    • Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
    • S. Gehrke, Y. Imai, N. Sokol, and B. Lu Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression Nature 466 2010 637 641
    • (2010) Nature , vol.466 , pp. 637-641
    • Gehrke, S.1    Imai, Y.2    Sokol, N.3    Lu, B.4
  • 30
    • 34848897853 scopus 로고    scopus 로고
    • MicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells
    • DOI 10.1073/pnas.0703037104
    • S.J. Greco, and P. Rameshwar MicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells Proc. Natl. Acad. Sci. USA 104 2007 15484 15489 (Pubitemid 47502943)
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , Issue.39 , pp. 15484-15489
    • Greco, S.J.1    Rameshwar, P.2
  • 31
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • DOI 10.1016/j.cell.2005.10.022, PII S0092867405011098
    • R.I. Gregory, T.P. Chendrimada, N. Cooch, and R. Shiekhattar Human RISC couples microRNA biogenesis and posttranscriptional gene silencing Cell 123 2005 631 640 (Pubitemid 41608466)
    • (2005) Cell , vol.123 , Issue.4 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 32
    • 42149172511 scopus 로고    scopus 로고
    • RNA interference of LRRK2-microarray expression analysis of a Parkinson's disease key player
    • K. Habig, M. Walter, S. Poths, O. Riess, and M. Bonin RNA interference of LRRK2-microarray expression analysis of a Parkinson's disease key player Neurogenetics 9 2008 83 94
    • (2008) Neurogenetics , vol.9 , pp. 83-94
    • Habig, K.1    Walter, M.2    Poths, S.3    Riess, O.4    Bonin, M.5
  • 35
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • DOI 10.1101/gad.1262504
    • J. Han, Y. Lee, K.H. Yeom, Y.K. Kim, H. Jin, and V.N. Kim The Drosha-DGCR8 complex in primary microRNA processing Genes Dev. 18 2004 3016 3027 (Pubitemid 39658171)
    • (2004) Genes and Development , vol.18 , Issue.24 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.-H.3    Kim, Y.-K.4    Jin, H.5    Kim, V.N.6
  • 38
    • 66249108936 scopus 로고    scopus 로고
    • Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells
    • P.G. Hawkins, S. Santoso, C. Adams, V. Anest, and K.V. Morris Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells Nucleic Acids Res. 37 2009 2984 2995
    • (2009) Nucleic Acids Res. , vol.37 , pp. 2984-2995
    • Hawkins, P.G.1    Santoso, S.2    Adams, C.3    Anest, V.4    Morris, K.V.5
  • 39
    • 63349094897 scopus 로고    scopus 로고
    • Alterations of the microRNA network cause neurodegenerative disease
    • S.S. Hebert, and B. De Strooper Alterations of the microRNA network cause neurodegenerative disease Trends Neurosci. 32 2009 199 206
    • (2009) Trends Neurosci. , vol.32 , pp. 199-206
    • Hebert, S.S.1    De Strooper, B.2
  • 43
    • 0032842360 scopus 로고    scopus 로고
    • Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter
    • M. Jaber, B. Dumartin, C. Sagné, J.W. Haycock, C. Roubert, B. Giros, B. Bloch, and M.G. Caron Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter Eur. J. Neurosci. 11 1999 3499 34511
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 3499-34511
    • Jaber, M.1    Dumartin, B.2    Sagné, C.3    Haycock, J.W.4    Roubert, C.5    Giros, B.6    Bloch, B.7    Caron, M.G.8
  • 44
    • 4744373229 scopus 로고    scopus 로고
    • Noise amidst the silence: Off-target effects of siRNAs?
    • DOI 10.1016/j.tig.2004.08.006, PII S0168952504002409
    • A.L. Jackson, and P.S. Linsley Noise amidst the silence: off-target effects of siRNAs? Trends Genet. 20 2004 521 524 (Pubitemid 39314555)
    • (2004) Trends in Genetics , vol.20 , Issue.11 , pp. 521-524
    • Jackson, A.L.1    Linsley, P.S.2
  • 46
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • DOI 10.1016/S0092-8674(03)00801-8
    • A. Khvorova, A. Reynolds, and S.D. Jayasena Functional siRNAs and miRNAs exhibit strand bias Cell 115 2003 209 216 (Pubitemid 37329584)
    • (2003) Cell , vol.115 , Issue.2 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 47
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • D.H. Kim, and J.J. Rossi Strategies for silencing human disease using RNA interference Nat. Rev. Genet. 8 2007 173 184
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 48
    • 33748368912 scopus 로고    scopus 로고
    • Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells
    • DOI 10.1038/nsmb1142, PII NSMB1142
    • D.H. Kim, L.M. Villeneuve, K.V. Morris, and J.J. Rossi Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells Nat. Struct. Mol. Biol. 13 2006 793 797 (Pubitemid 44338773)
    • (2006) Nature Structural and Molecular Biology , vol.13 , Issue.9 , pp. 793-797
    • Kim, D.H.1    Villeneuve, L.M.2    Morris, K.V.3    Rossi, J.J.4
  • 51
    • 55849135596 scopus 로고    scopus 로고
    • MicroRNA-directed transcriptional gene silencing in mammalian cells
    • D.H. Kim, P. Saetrom, O. Snove Jr., and J.J. Rossi MicroRNA-directed transcriptional gene silencing in mammalian cells Proc. Natl. Acad. Sci. USA 105 2008 16230 16235
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 16230-16235
    • Kim, D.H.1    Saetrom, P.2    Snove, Jr.O.3    Rossi, J.J.4
  • 52
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
    • S.J. Kish, K. Shannak, and O. Hornykiewicz Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications N. Engl. J. Med. 318 1988 876 880 (Pubitemid 18090271)
    • (1988) New England Journal of Medicine , vol.318 , Issue.14 , pp. 876-880
    • Kish, S.J.1    Shannak, K.2    Hornykiewicz, O.3
  • 53
    • 5444269702 scopus 로고    scopus 로고
    • Parkinson's disease: Clinical aspects
    • DOI 10.1007/s00441-004-0975-6
    • T. Klockgether Parkinson's disease: clinical aspects Cell Tissue Res. 318 2004 115 120 (Pubitemid 39362632)
    • (2004) Cell and Tissue Research , vol.318 , Issue.1 , pp. 115-120
    • Klockgether, T.1
  • 57
    • 33847134493 scopus 로고    scopus 로고
    • Apoptosis-inducing factor: A matter of neuron life and death
    • DOI 10.1016/j.pneurobio.2006.12.002, PII S0301008206001638
    • S. Krantic, N. Mechawar, S. Reix, and R. Quirion Apoptosis-inducing factor: a matter of neuron life and death Prog. Neurobiol. 81 2007 179 196 (Pubitemid 46282274)
    • (2007) Progress in Neurobiology , vol.81 , Issue.3 , pp. 179-196
    • Krantic, S.1    Mechawar, N.2    Reix, S.3    Quirion, R.4
  • 58
    • 52949083619 scopus 로고    scopus 로고
    • A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans
    • T. Kuwahara, A. Koyama, S. Koyama, S. Yoshina, C.H. Ren, T. Kato, S. Mitani, and T. Iwatsubo A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans Hum. Mol. Genet. 17 2008 2997 3009
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 2997-3009
    • Kuwahara, T.1    Koyama, A.2    Koyama, S.3    Yoshina, S.4    Ren, C.H.5    Kato, T.6    Mitani, S.7    Iwatsubo, T.8
  • 59
    • 0020680904 scopus 로고
    • Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
    • J.W. Langston, P. Ballard, J.W. Tetrud, and I. Irwin Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis Science 219 1983 979 980 (Pubitemid 13189531)
    • (1983) Science , vol.219 , Issue.4587 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3    Irwin, I.4
  • 62
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • DOI 10.1038/sj.emboj.7600385
    • Y. Lee, M. Kim, J. Han, K.H. Yeom, S. Lee, S.H. Baek, and V.N. Kim MicroRNA genes are transcribed by RNA polymerase II EMBO J. 23 2004 4051 4060 (Pubitemid 39472426)
    • (2004) EMBO Journal , vol.23 , Issue.20 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.-H.4    Lee, S.5    Baek, S.H.6    Kim, V.N.7
  • 63
    • 68949203453 scopus 로고    scopus 로고
    • A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: Implications for Parkinson's disease
    • D.W. Lee, D. Kaur, S.J. Chinta, S. Rajagopalan, and J.K. Andersen A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's disease Antioxid. Redox Signal. 11 2009 2083 2094
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 2083-2094
    • Lee, D.W.1    Kaur, D.2    Chinta, S.J.3    Rajagopalan, S.4    Andersen, J.K.5
  • 64
    • 78651259607 scopus 로고    scopus 로고
    • Anti-inflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells
    • I.S. Lee, J. Lim, J. Gal, J.C. Kang, H.J. Kim, B.Y. Kang, and H.J. Choi Anti-inflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells Neurochem. Int. 58 2011 153 160
    • (2011) Neurochem. Int. , vol.58 , pp. 153-160
    • Lee, I.S.1    Lim, J.2    Gal, J.3    Kang, J.C.4    Kim, H.J.5    Kang, B.Y.6    Choi, H.J.7
  • 68
    • 11844263960 scopus 로고    scopus 로고
    • Analysis of short interfering RNA function in RNA interference by using Drosophila embryo extracts and Schneider cells
    • DOI 10.1016/S0076-6879(04)92021-6, PII S0076687904920216
    • C. Lipardi, H.J. Baek, Q. Wei, and B.M. Paterson Analysis of short interfering RNA function in RNA interference by using Drosophila embryo extracts and Schneider cells Methods Enzymol. 392 2005 351 371 (Pubitemid 40092525)
    • (2005) Methods in Enzymology , vol.392 , pp. 351-371
    • Lipardi, C.1    Baek, H.J.2    Wei, Q.3    Paterson, B.M.4
  • 71
    • 52949090397 scopus 로고    scopus 로고
    • Striatal 19S Rpt6 deficit is related to alpha-synuclein accumulation in MPTP-treated mice
    • B. Liu, Q. Shi, S. Ma, N. Feng, J. Li, L. Wang, and X. Wang Striatal 19S Rpt6 deficit is related to alpha-synuclein accumulation in MPTP-treated mice Biochem. Biophys. Res. Commun. 376 2008 277 282
    • (2008) Biochem. Biophys. Res. Commun. , vol.376 , pp. 277-282
    • Liu, B.1    Shi, Q.2    Ma, S.3    Feng, N.4    Li, J.5    Wang, L.6    Wang, X.7
  • 73
    • 44649174333 scopus 로고    scopus 로고
    • Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease
    • DOI 10.1111/j.1471-4159.2008.05333.x
    • F. Liu, J.L. Nguyen, J.D. Hulleman, L. Li, and J.C. Rochet Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease J. Neurochem. 105 2008 2435 2453 (Pubitemid 351782273)
    • (2008) Journal of Neurochemistry , vol.105 , Issue.6 , pp. 2435-2453
    • Liu, F.1    Nguyen, J.L.2    Hulleman, J.D.3    Li, L.4    Rochet, J.-C.5
  • 75
    • 70949099222 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 5, overexpressed in the alpha-synuclein up-regulation model of Parkinson's disease, regulates bcl-2 expression
    • P. Liu, X. Wang, N. Gao, H. Zhu, X. Dai, Y. Xu, C. Ma, L. Huang, Y. Liu, and C. Qin G protein-coupled receptor kinase 5, overexpressed in the alpha-synuclein up-regulation model of Parkinson's disease, regulates bcl-2 expression Brain Res. 1307 2010 134 141
    • (2010) Brain Res. , vol.1307 , pp. 134-141
    • Liu, P.1    Wang, X.2    Gao, N.3    Zhu, H.4    Dai, X.5    Xu, Y.6    Ma, C.7    Huang, L.8    Liu, Y.9    Qin, C.10
  • 76
    • 68149154977 scopus 로고    scopus 로고
    • Recent advances in using Drosophila to model neurodegenerative diseases
    • B. Lu Recent advances in using Drosophila to model neurodegenerative diseases Apoptosis 14 2009 1008 1020
    • (2009) Apoptosis , vol.14 , pp. 1008-1020
    • Lu, B.1
  • 77
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear Export of MicroRNA Precursors
    • DOI 10.1126/science.1090599
    • E. Lund, S. Güttinger, A. Calado, J.E. Dahlberg, and U. Kutay Nuclear export of microRNA precursors Science 303 2004 95 98 (Pubitemid 38055779)
    • (2004) Science , vol.303 , Issue.5654 , pp. 95-98
    • Lund, E.1    Guttinger, S.2    Calado, A.3    Dahlberg, J.E.4    Kutay, U.5
  • 80
    • 77957928823 scopus 로고    scopus 로고
    • Meiotic silencing in Caenorhabditis elegans
    • E.M. Maine Meiotic silencing in Caenorhabditis elegans Int. Rev. Cell Mol. Biol. 282 2010 91 134
    • (2010) Int. Rev. Cell Mol. Biol. , vol.282 , pp. 91-134
    • Maine, E.M.1
  • 81
    • 33645159024 scopus 로고    scopus 로고
    • RNA knockdown as a potential therapeutic strategy in Parkinson's disease
    • F.P. Manfredsson, A.S. Lewin, and R.J. Mandel RNA knockdown as a potential therapeutic strategy in Parkinson's disease Gene Ther. 13 2006 517 524
    • (2006) Gene Ther. , vol.13 , pp. 517-524
    • Manfredsson, F.P.1    Lewin, A.S.2    Mandel, R.J.3
  • 82
    • 0031668934 scopus 로고    scopus 로고
    • The causes of Parkinson's disease are being unraveled and rational neuroprotective therapy is close to reality
    • C.D. Marsden, and C.W. Olanow The causes of Parkinson's disease are being unraveled and rational neuroprotective therapy is close to reality Ann. Neurol. 44 1998 S189 S196
    • (1998) Ann. Neurol. , vol.44
    • Marsden, C.D.1    Olanow, C.W.2
  • 83
    • 8744234971 scopus 로고    scopus 로고
    • RNA-directed DNA methylation
    • DOI 10.1242/jcs.01479
    • O. Mathieu, and J. Bender RNA-directed DNA methylation J. Cell Sci. 117 2004 4881 4888 (Pubitemid 39517505)
    • (2004) Journal of Cell Science , vol.117 , Issue.21 , pp. 4881-4888
    • Mathieu, O.1    Bender, J.2
  • 85
    • 34249025114 scopus 로고    scopus 로고
    • Prediction of microRNA targets
    • DOI 10.1016/j.drudis.2007.04.002, PII S1359644607001493
    • P. Maziere, and A.J. Enright Prediction of microRNA targets Drug Discov. Today 12 2007 452 458 (Pubitemid 46795589)
    • (2007) Drug Discovery Today , vol.12 , Issue.11-12 , pp. 452-458
    • Maziere, P.1    Enright, A.J.2
  • 86
    • 77957877526 scopus 로고    scopus 로고
    • Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra
    • A.L. McCormack, S.K. Mak, J.M. Henderson, D. Bumcrot, M.J. Farrer, and D.A. Di Monte Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra PLoS One 5 2010 e12122
    • (2010) PLoS One , vol.5 , pp. 12122
    • McCormack, A.L.1    Mak, S.K.2    Henderson, J.M.3    Bumcrot, D.4    Farrer, M.J.5    Di Monte, D.A.6
  • 87
    • 80255133088 scopus 로고    scopus 로고
    • Dopamine transporter and vesicular monoamine transporter knockout mice: Implications for Parkinson's disease
    • G.W. Miller, Y.M. Wang, R.R. Gainetdinov, and M.G. Caron Dopamine transporter and vesicular monoamine transporter knockout mice: implications for Parkinson's disease Methods Mol. Med. 62 2001 179 190
    • (2001) Methods Mol. Med. , vol.62 , pp. 179-190
    • Miller, G.W.1    Wang, Y.M.2    Gainetdinov, R.R.3    Caron, M.G.4
  • 88
    • 68249104469 scopus 로고    scopus 로고
    • Emerging role of LRRK2 in human neural progenitor cell cycle progression, survival and differentiation
    • J. Milosevic, S.C. Schwarz, V. Ogunlade, A.K. Meyer, A. Storch, and J. Schwarz Emerging role of LRRK2 in human neural progenitor cell cycle progression, survival and differentiation Mol. Neurodegener. 4 2009 25
    • (2009) Mol. Neurodegener. , vol.4 , pp. 25
    • Milosevic, J.1    Schwarz, S.C.2    Ogunlade, V.3    Meyer, A.K.4    Storch, A.5    Schwarz, J.6
  • 89
    • 2342485506 scopus 로고    scopus 로고
    • MiRNAs on the move: miRNA biogenesis and the RNAi machinery
    • DOI 10.1016/j.ceb.2004.04.003, PII S0955067404000547
    • E.P. Murchison, and G.J. Hannon MiRNAs on the move: miRNA biogenesis and the RNAi machinery Curr. Opin. Cell Biol. 16 2004 223 229 (Pubitemid 38610401)
    • (2004) Current Opinion in Cell Biology , vol.16 , Issue.3 , pp. 223-229
    • Murchison, E.P.1    Hannon, G.J.2
  • 90
    • 38349186896 scopus 로고    scopus 로고
    • MicroRNAs (miRNAs) in neurodegenerative diseases
    • P.T. Nelson, W.X. Wang, and B.W. Rajeev MicroRNAs (miRNAs) in neurodegenerative diseases Brain Pathol. 18 2008 130 138
    • (2008) Brain Pathol. , vol.18 , pp. 130-138
    • Nelson, P.T.1    Wang, W.X.2    Rajeev, B.W.3
  • 91
    • 33644992707 scopus 로고    scopus 로고
    • In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5
    • T. Ohrt, D. Merkle, K. Birkenfeld, C.J. Echeverri, and P. Schwille In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5 Nucleic Acids Res. 34 2006 1369 1380
    • (2006) Nucleic Acids Res. , vol.34 , pp. 1369-1380
    • Ohrt, T.1    Merkle, D.2    Birkenfeld, K.3    Echeverri, C.J.4    Schwille, P.5
  • 93
    • 33644958235 scopus 로고    scopus 로고
    • Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells
    • M. Ouyang, and X. Shen Critical role of ASK1 in the 6-hydroxydopamine- induced apoptosis in human neuroblastoma SH-SY5Y cells J. Neurochem. 97 2006 234 244
    • (2006) J. Neurochem. , vol.97 , pp. 234-244
    • Ouyang, M.1    Shen, X.2
  • 94
    • 0942279615 scopus 로고    scopus 로고
    • Heterochromatic Silencing and HP1 Localization in Drosophila Are Dependent on the RNAi Machinery
    • DOI 10.1126/science.1092653
    • M. Pal-Bhadra, B.A. Leibovitch, S.G. Gandhi, M. Rao, U. Bhadra, J.A. Birchler, and S.C. Elgin Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery Science 303 2004 669 672 (Pubitemid 38141632)
    • (2004) Science , vol.303 , Issue.5658 , pp. 669-672
    • Pal-Bhadra, M.1    Leibovitch, B.A.2    Gandhi, S.G.3    Rao, M.4    Bhadra, U.5    Birchler, J.A.6    Elgin, S.C.R.7
  • 95
    • 3142731321 scopus 로고    scopus 로고
    • Intravenous, non-viral RNAi gene therapy of brain cancer
    • DOI 10.1517/14712598.4.7.1103
    • W.M. Pardridge Intravenous, non-viral RNAi gene therapy of brain cancer Expert Opin. Biol. Ther. 4 2004 1103 1113 (Pubitemid 38937552)
    • (2004) Expert Opinion on Biological Therapy , vol.4 , Issue.7 , pp. 1103-1113
    • Pardridge, W.M.1
  • 96
    • 34248679586 scopus 로고    scopus 로고
    • ShRNA and siRNA delivery to the brain
    • DOI 10.1016/j.addr.2007.03.008, PII S0169409X07000221, Opportunities and Challenges for Therapeutic Gene Silencing using RNAi and microRNA Technologies
    • W.M. Pardridge ShRNA and siRNA delivery to the brain Adv. Drug Deliv. Rev. 59 2007 141 152 (Pubitemid 46773051)
    • (2007) Advanced Drug Delivery Reviews , vol.59 , Issue.2-3 , pp. 141-152
    • Pardridge, W.M.1
  • 98
    • 33645739484 scopus 로고    scopus 로고
    • Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: Mechanism of neurodegeneration
    • S. Patel, V. Singh, A. Kumar, Y.K. Gupta, and M.P. Singh Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration Brain Res. 1081 2006 9 18
    • (2006) Brain Res. , vol.1081 , pp. 9-18
    • Patel, S.1    Singh, V.2    Kumar, A.3    Gupta, Y.K.4    Singh, M.P.5
  • 99
    • 0025815998 scopus 로고
    • Pathological changes in dendrites of substantia nigra neurons in Parkinson's disease: A Golgi study
    • S. Patt, H.J. Gertz, L. Gerhard, and J. Cervos-Navarro Pathological changes in dendrites of substantia nigra neurons in Parkinson's disease: a Golgi study Histol. Histopathol. 6 1991 373 380
    • (1991) Histol. Histopathol. , vol.6 , pp. 373-380
    • Patt, S.1    Gertz, H.J.2    Gerhard, L.3    Cervos-Navarro, J.4
  • 100
    • 0037137702 scopus 로고    scopus 로고
    • Parkin protects against the toxicity associated with mutant α-Synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
    • DOI 10.1016/S0896-6273(02)01125-X
    • L. Petrucelli, C. O'Farrell, P.J. Lockhart, M. Baptista, K. Kehoe, L. Vink, P. Choi, B. Wolozin, M. Farrer, J. Hardy, and M.R. Cookson Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons Neuron 36 2002 1007 1019 (Pubitemid 36044504)
    • (2002) Neuron , vol.36 , Issue.6 , pp. 1007-1019
    • Petrucelli, L.1    O'Farrell, C.2    Lockhart, P.J.3    Baptista, M.4    Kehoe, K.5    Vink, L.6    Choi, P.7    Wolozin, B.8    Farrer, M.9    Hardy, J.10    Cookson, M.R.11
  • 103
    • 70350126990 scopus 로고    scopus 로고
    • Regulation of non-coding RNA networks in the nervous system - What's the REST of the story?
    • I.A. Qureshi, and M.F. Mehler Regulation of non-coding RNA networks in the nervous system - what's the REST of the story? Neurosci. Lett. 466 2009 73 80
    • (2009) Neurosci. Lett. , vol.466 , pp. 73-80
    • Qureshi, I.A.1    Mehler, M.F.2
  • 107
    • 71749092463 scopus 로고    scopus 로고
    • MicroRNAs: Novel therapeutic targets in neurodegenerative diseases
    • R. Roshan, T. Ghosh, V. Scaria, and B. Pillai MicroRNAs: novel therapeutic targets in neurodegenerative diseases Drug Discov. Today 14 2009 1123 1129
    • (2009) Drug Discov. Today , vol.14 , pp. 1123-1129
    • Roshan, R.1    Ghosh, T.2    Scaria, V.3    Pillai, B.4
  • 108
    • 33845201282 scopus 로고    scopus 로고
    • Local Knockdown of Genes in the Brain Using Small Interfering RNA: A Phenotypic Comparison with Knockout Animals
    • DOI 10.1016/j.biopsych.2006.03.020, PII S0006322306003969
    • A. Salahpour, I.O. Medvedev, J.M. Beaulieu, R.R. Gainetdinov, and M.G. Caron Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals Biol. Psychiatry 61 2007 65 69 (Pubitemid 44855739)
    • (2007) Biological Psychiatry , vol.61 , Issue.1 , pp. 65-69
    • Salahpour, A.1    Medvedev, I.O.2    Beaulieu, J.-M.3    Gainetdinov, R.R.4    Caron, M.G.5
  • 109
    • 71149102204 scopus 로고    scopus 로고
    • Interaction map and selection of microRNA targets in Parkinson's disease-related genes
    • P.S. Santosh, N. Arora, P. Sarma, M. Pal-Bhadra, and U. Bhadra Interaction map and selection of microRNA targets in Parkinson's disease-related genes J. Biomed. Biotechnol. 2009 2009 363145
    • (2009) J. Biomed. Biotechnol. , vol.2009 , pp. 363145
    • Santosh, P.S.1    Arora, N.2    Sarma, P.3    Pal-Bhadra, M.4    Bhadra, U.5
  • 110
    • 0142173075 scopus 로고    scopus 로고
    • Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells
    • DOI 10.1074/jbc.M307089200
    • S. Saxena, Z.O. Jonsson, and A. Dutta Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells J. Biol. Chem. 278 2003 44312 44319 (Pubitemid 37377177)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.45 , pp. 44312-44319
    • Saxena, S.1    Jonsson, Z.O.2    Dutta, A.3
  • 112
    • 31144479591 scopus 로고    scopus 로고
    • A brain-specific microRNA regulates dendritic spine development
    • DOI 10.1038/nature04367, PII NATURE04367
    • G.M. Schratt, F. Tuebing, E.A. Nigh, C.G. Kane, M.E. Sabatini, M. Kiebler, and M.E. Greenberg A brain-specific microRNA regulates dendritic spine development Nature 439 2006 283 289 (Pubitemid 43128846)
    • (2006) Nature , vol.439 , Issue.7074 , pp. 283-289
    • Schratt, G.M.1    Tuebing, F.2    Nigh, E.A.3    Kane, C.G.4    Sabatini, M.E.5    Kiebler, M.6    Greenberg, M.E.7
  • 113
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • DOI 10.1016/S0092-8674(03)00759-1
    • D.S. Schwarz, G. Hutvagner, T. Du, Z. Xu, N. Aronin, and P.D. Zamore Asymmetry in the assembly of the RNAi enzyme complex Cell 115 2003 199 208 (Pubitemid 37329583)
    • (2003) Cell , vol.115 , Issue.2 , pp. 199-208
    • Schwarz, D.S.1    Hutvagner, G.2    Du, T.3    Xu, Z.4    Aronin, N.5    Zamore, P.D.6
  • 114
    • 33749184503 scopus 로고    scopus 로고
    • Contribution of genomics and proteomics in understanding the role of modifying factors in Parkinson's disease
    • M.P. Singh, S. Patel, M. Dikshit, and Y.K. Gupta Contribution of genomics and proteomics in understanding the role of modifying factors in Parkinson's disease Indian J. Biochem. Biophys. 43 2006 69 81 (Pubitemid 44475398)
    • (2006) Indian Journal of Biochemistry and Biophysics , vol.43 , Issue.2 , pp. 69-81
    • Singh, M.P.1    Patel, S.2    Dikshit, M.3    Gupta, Y.K.4
  • 115
    • 34447271264 scopus 로고    scopus 로고
    • Pesticides and metals induced Parkinson's disease: Involvement of free radicals and oxidative stress
    • DOI 10.1170/T815
    • C. Singh, I. Ahmad, and A. Kumar Pesticides and metals induced Parkinson's disease: involvement of free radicals and oxidative stress Cell. Mol. Biol. (Noisy-le-grand) 53 2007 19 28 (Pubitemid 350164302)
    • (2007) Cellular and Molecular Biology , vol.53 , Issue.5 , pp. 19-28
    • Singh, C.1    Ahmad, I.2    Kumar, A.3
  • 116
    • 70349250528 scopus 로고    scopus 로고
    • The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection
    • S. Singh, K. Singh, D.K. Patel, C. Singh, C. Nath, V.K. Singh, R.K. Singh, and M.P. Singh The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6- tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection Rejuvenation Res. 12 2009 185 197
    • (2009) Rejuvenation Res. , vol.12 , pp. 185-197
    • Singh, S.1    Singh, K.2    Patel, D.K.3    Singh, C.4    Nath, C.5    Singh, V.K.6    Singh, R.K.7    Singh, M.P.8
  • 117
    • 82755192147 scopus 로고    scopus 로고
    • Long term exposure to cypermethrin induces nigrostriatal dopaminergic neurodegeneration in adult rats: Postnatal exposure enhances the susceptibility during adulthood
    • 10.1016/j.neurobiolagin
    • A.K. Singh, M.N. Tiwari, G. Upadhyay, D.K. Patel, D. Singh, O. Prakash, and M.P. Singh Long term exposure to cypermethrin induces nigrostriatal dopaminergic neurodegeneration in adult rats: postnatal exposure enhances the susceptibility during adulthood Neurobiol. Aging 2010 10.1016/j.neurobiolagin
    • (2010) Neurobiol. Aging
    • Singh, A.K.1    Tiwari, M.N.2    Upadhyay, G.3    Patel, D.K.4    Singh, D.5    Prakash, O.6    Singh, M.P.7
  • 118
    • 79951634450 scopus 로고    scopus 로고
    • Melatonin or silymarin reduces maneb- and paraquat-induced Parkinson's disease phenotype in the mouse
    • N.K. Singhal, G. Srivastava, D.K. Patel, S.K. Jain, and M.P. Singh Melatonin or silymarin reduces maneb- and paraquat-induced Parkinson's disease phenotype in the mouse J. Pineal Res. 50 2011 97 109
    • (2011) J. Pineal Res. , vol.50 , pp. 97-109
    • Singhal, N.K.1    Srivastava, G.2    Patel, D.K.3    Jain, S.K.4    Singh, M.P.5
  • 119
    • 57949085678 scopus 로고    scopus 로고
    • Identification of differentially displayed proteins in cerebrospinal fluid of Parkinson's disease patients: A proteomic approach
    • A. Sinha, N. Srivastava, S. Singh, A.K. Singh, S. Bhushan, R. Shukla, and M.P. Singh Identification of differentially displayed proteins in cerebrospinal fluid of Parkinson's disease patients: a proteomic approach Clin. Chim. Acta 400 2009 14 20
    • (2009) Clin. Chim. Acta , vol.400 , pp. 14-20
    • Sinha, A.1    Srivastava, N.2    Singh, S.3    Singh, A.K.4    Bhushan, S.5    Shukla, R.6    Singh, M.P.7
  • 121
    • 77951648520 scopus 로고    scopus 로고
    • Proteomics in Parkinson's disease: Current trends, translational snags and future possibilities
    • G. Srivastava, K. Singh, M.N. Tiwari, and M.P. Singh Proteomics in Parkinson's disease: current trends, translational snags and future possibilities Expert Rev. Proteomics 7 2010 127 139
    • (2010) Expert Rev. Proteomics , vol.7 , pp. 127-139
    • Srivastava, G.1    Singh, K.2    Tiwari, M.N.3    Singh, M.P.4
  • 122
    • 50349087243 scopus 로고    scopus 로고
    • Self-assembled biodegradable micellar nanoparticles of amphiphilic and cationic block copolymer for siRNA delivery
    • T.M. Sun, J.Z. Du, L.F. Yan, H.Q. Mao, and J. Wang Self-assembled biodegradable micellar nanoparticles of amphiphilic and cationic block copolymer for siRNA delivery Biomaterials 29 2008 4348 4355
    • (2008) Biomaterials , vol.29 , pp. 4348-4355
    • Sun, T.M.1    Du, J.Z.2    Yan, L.F.3    Mao, H.Q.4    Wang, J.5
  • 123
    • 67349208210 scopus 로고    scopus 로고
    • Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: Implications for schizophrenia, autism and cancer
    • R. Tabares-Seisdedos, and J.L. Rubenstein Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer Mol. Psychiatry 14 2009 563 589
    • (2009) Mol. Psychiatry , vol.14 , pp. 563-589
    • Tabares-Seisdedos, R.1    Rubenstein, J.L.2
  • 124
    • 1642527499 scopus 로고    scopus 로고
    • DJ-1 has a role in antioxidative stress to prevent cell death
    • DOI 10.1038/sj.embor.7400074
    • T. Taira, Y. Saito, T. Niki, S.M. Iguchi-Ariga, K. Takahashi, and H. Ariga DJ-1 has a role in antioxidative stress to prevent cell death EMBO Rep. 5 2004 213 218 (Pubitemid 38401204)
    • (2004) EMBO Reports , vol.5 , Issue.2 , pp. 213-218
    • Taira, T.1    Saito, Y.2    Niki, T.3    Iguchi-Ariga, S.M.M.4    Takahashi, K.5    Ariga, H.6
  • 125
    • 13244278197 scopus 로고    scopus 로고
    • SiRNA and miRNA: An insight into RISCs
    • DOI 10.1016/j.tibs.2004.12.007, PII S0968000404003214
    • G. Tang SiRNA and miRNA: an insight into RISCs Trends Biochem. Sci. 30 2005 106 114 (Pubitemid 40187303)
    • (2005) Trends in Biochemical Sciences , vol.30 , Issue.2 , pp. 106-114
    • Tang, G.1
  • 126
    • 77953468252 scopus 로고    scopus 로고
    • Advances in environmental epidemiology
    • C.M. Tanner Advances in environmental epidemiology Mov. Disord. 25 2010 S58 S62
    • (2010) Mov. Disord. , vol.25
    • Tanner, C.M.1
  • 127
    • 35348966882 scopus 로고    scopus 로고
    • Neuroinflammatory mechanisms in Parkinson's disease: Potential environmental triggers, pathways, and targets for early therapeutic intervention
    • DOI 10.1016/j.expneurol.2007.07.004, PII S0014488607002701
    • M.G. Tansey, M.K. McCoy, and T.C. Frank-Cannon Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention Exp. Neurol. 208 2007 1 25 (Pubitemid 47603240)
    • (2007) Experimental Neurology , vol.208 , Issue.1 , pp. 1-25
    • Tansey, M.G.1    McCoy, M.K.2    Frank-Cannon, T.C.3
  • 128
    • 14644393684 scopus 로고    scopus 로고
    • Perspective: Machines for RNAi
    • DOI 10.1101/gad.1284105
    • Y. Tomari, and P.D. Zamore Perspective: machines for RNAi Genes Dev. 19 2005 517 529 (Pubitemid 40314984)
    • (2005) Genes and Development , vol.19 , Issue.5 , pp. 517-529
    • Tomari, Y.1    Zamore, P.D.2
  • 131
  • 132
    • 67649804671 scopus 로고    scopus 로고
    • 14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: Localization of dopamine regulatory proteins to mitochondria
    • J. Wang, H. Lou, C.J. Pedersen, A.D. Smith, and R.G. Perez 14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria J. Biol. Chem. 284 2009 14011 14019
    • (2009) J. Biol. Chem. , vol.284 , pp. 14011-14019
    • Wang, J.1    Lou, H.2    Pedersen, C.J.3    Smith, A.D.4    Perez, R.G.5
  • 134
    • 34247172025 scopus 로고    scopus 로고
    • 2′-Fluoro-4′-thioarabino-modified oligonucleotides: Conformational switches linked to siRNA activity
    • DOI 10.1093/nar/gkl1153
    • J.K. Watts, N. Choubdar, K. Sadalapure, F. Robert, A.S. Wahba, J. Pelletier, B.M. Pinto, and M.J. Damha 2′-Fluoro-4′-thioarabino- modified oligonucleotides: conformational switches linked to siRNA activity Nucleic Acids Res. 35 2007 1441 1451 (Pubitemid 46592867)
    • (2007) Nucleic Acids Research , vol.35 , Issue.5 , pp. 1441-1451
    • Watts, J.K.1    Choubdar, N.2    Sadalapure, K.3    Robert, F.4    Wahba, A.S.5    Pelletier, J.6    Pinto, B.M.7    Damha, M.J.8
  • 136
    • 27144475302 scopus 로고    scopus 로고
    • Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells
    • DOI 10.1128/MCB.25.21.9198-9208.2005
    • L. Wu, and J.G. Belasco Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells Mol. Cell. Biol. 25 2005 9198 9208 (Pubitemid 41507823)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.21 , pp. 9198-9208
    • Wu, L.1    Belasco, J.G.2
  • 138
    • 0037468831 scopus 로고    scopus 로고
    • Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
    • DOI 10.1016/S0896-6273(03)00143-0
    • Y. Yang, I. Nishimura, Y. Imai, R. Takahashi, and B. Lu Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila Neuron 37 2003 911 924 (Pubitemid 36398298)
    • (2003) Neuron , vol.37 , Issue.6 , pp. 911-924
    • Yang, Y.1    Nishimura, I.2    Imai, Y.3    Takahashi, R.4    Lu, B.5
  • 140
    • 33746368839 scopus 로고    scopus 로고
    • Inflammatory cytokine induction by siRNAs is cell type- and transfection reagent-specific
    • DOI 10.1016/j.bbrc.2006.07.001, PII S0006291X06015221
    • J.W. Yoo, S.W. Hong, S. Kim, and D.K. Lee Inflammatory cytokine induction by siRNAs is cell type- and transfection reagent-specific Biochem. Biophys. Res. Commun. 347 2006 1053 1058 (Pubitemid 44118221)
    • (2006) Biochemical and Biophysical Research Communications , vol.347 , Issue.4 , pp. 1053-1058
    • Yoo, J.W.1    Hong, S.W.2    Kim, S.3    Lee, D.-k.4
  • 141
    • 34047139460 scopus 로고    scopus 로고
    • A novel role of glia maturation factor: Induction of granulocyte- macrophage colony-stimulating factor and pro-inflammatory cytokines
    • DOI 10.1111/j.1471-4159.2006.04385.x
    • A. Zaheer, S. Zaheer, S.K. Sahu, S. Knight, H. Khosravi, S.N. Mathur, and R. Lim A novel role of glia maturation factor: induction of granulocyte-macrophage colony-stimulating factor and pro-inflammatory cytokines J. Neurochem. 101 2007 364 376 (Pubitemid 46525279)
    • (2007) Journal of Neurochemistry , vol.101 , Issue.2 , pp. 364-376
    • Zaheer, A.1    Zaheer, S.2    Sahu, S.K.3    Knight, S.4    Khosravi, H.5    Mathur, S.N.6    Lim, R.7
  • 143
    • 34548101125 scopus 로고    scopus 로고
    • Neuroprotective effect of protein kinase Cδ inhibitor rottlerin in cell culture and animal models of Parkinson's disease
    • DOI 10.1124/jpet.107.124669
    • D. Zhang, V. Anantharam, A. Kanthasamy, and A.G. Kanthasamy Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease J. Pharmacol. Exp. Ther. 322 2007 913 922 (Pubitemid 47295809)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.322 , Issue.3 , pp. 913-922
    • Zhang, D.1    Anantharam, V.2    Kanthasamy, A.3    Kanthasamy, A.G.4
  • 144
    • 33746355607 scopus 로고    scopus 로고
    • DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor
    • DOI 10.1074/jbc.M601935200
    • N. Zhong, C.Y. Kim, P. Rizzu, C. Geula, D.R. Porter, E.N. Pothos, F. Squitieri, P. Heutink, and J. Xu DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor J. Biol. Chem. 281 2006 20940 20948 (Pubitemid 44115435)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.30 , pp. 20940-20948
    • Zhong, N.1    Kim, C.Y.2    Rizzu, P.3    Geula, C.4    Porter, D.R.5    Pothos, E.N.6    Squitieri, F.7    Heutink, P.8    Xu, J.9
  • 146
    • 77950384477 scopus 로고    scopus 로고
    • Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
    • E. Ziviani, R.N. Tao, and A.J. Whitworth Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin Proc. Natl. Acad. Sci. USA 107 2010 5018 5023
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 5018-5023
    • Ziviani, E.1    Tao, R.N.2    Whitworth, A.J.3


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