Local Knockdown of Genes in the Brain Using Small Interfering RNA: A Phenotypic Comparison with Knockout Animals

Biological Psychiatry

Volumn 61, Issue 1, 2007, Pages 65-69

  Salahpour, Ali ^a   Medvedev, Ivan O ^a   Beaulieu, Jean Martin ^a   Gainetdinov, Raul R ^a   Caron, Marc G ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Amphetamine; dopamine; dopamine transporter; knockout mice; RNA interference; tyrosine hydroxylase

Indexed keywords

SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; HETEROZYGOSITY; LOCOMOTION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SUBSTANTIA NIGRA; TRANSGENICS; VENTRAL TEGMENTUM; WILD TYPE;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BRAIN; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DRUG ADMINISTRATION ROUTES; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; RNA, SMALL INTERFERING; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 33845201282     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2006.03.020     Document Type: Article

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