Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome c. Protection against apoptosis versus delayed oxidative stress in Parkinson disease

Journal of Biological Chemistry

Volumn 284, Issue 23, 2009, Pages 15951-15969

  Bayir, Hülya ^a,b,d   Kapralov, Alexandr A ^a   Jiang, Janfei ^a   Huang, Zhentai ^a   Tyurina, Yulia Y ^a   Tyurin, Vladimir A ^a   Zhao, Qing ^a   Belikova, Natalia A ^a   Vlasova, Irina I ^a   Maeda, Akihiro ^a   Zhu, Jianhui ^b   Na, Hye Mee ^b,c   Mastroberardino, Pier Giorgio ^b   Sparvero, Louis J ^c   Amoscato, Andrew A ^c   Chu, Charleen T ^b   Greenamyre, John T ^b   Kagan, Valerian E ^a,e  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^d CCM Office   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIONIC LIPIDS; APOPTOSIS; CARDIOLIPIN; CASPASE-3 ACTIVATION; CELL-FREE SYSTEM; COLOCALIZATION; CYTOCHROME C; EMBRYONIC CELLS; HELA CELL; HETERO-OLIGOMERIZATION; HIGH MOLECULAR WEIGHT; INDUCED APOPTOSIS; NEURITES; PARKINSON DISEASE; PEROXIDASE ACTIVITIES; PHENOLIC SUBSTRATES; PRESYNAPTIC; PRO-APOPTOTIC FACTORS; PROTECTIVE FUNCTION; SMALL INTERFERING RNA; SUBSTANTIA NIGRA; SYNUCLEIN;

ANTIGENS; BRAIN; CELL MEMBRANES; DYES; NEURONS; NUCLEIC ACIDS; OLIGOMERIZATION; PHENOLS; PHOSPHOLIPIDS; RNA; SUBSTRATES;

CELL DEATH;

ALPHA SYNUCLEIN; CARDIOLIPIN; CASPASE 3; CYTOCHROME C; DOPAMINE; PEROXIDASE; SMALL INTERFERING RNA; CROSS LINKING REAGENT; LIPID; SYNUCLEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEWY BODY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OLIGOMERIZATION; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CROSS LINKING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SUBSTANTIA NIGRA; ANIMAL; ENZYMOLOGY; GENETICS; HELA CELL; METABOLISM; MOLECULAR CLONING; NERVE CELL; NEUROBLASTOMA; PARKINSON DISEASE; PATHOPHYSIOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

RATTUS;

ANIMALS; APOPTOSIS; CARDIOLIPINS; CELL LINE, TUMOR; CLONING, MOLECULAR; CROSS-LINKING REAGENTS; CYTOCHROMES C; HELA CELLS; HUMANS; LIPIDS; MICE; NEUROBLASTOMA; NEURONS; OXIDATIVE STRESS; PARKINSON DISEASE; PEROXIDASES; RNA, SMALL INTERFERING; SYNUCLEINS;

EID: 67650156461     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M900418200     Document Type: Article

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