GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 31, 2008, Pages 10907-10912

  Scherzer, Clemens R ^a   Grass, Jeffrey A ^b   Liao, Zhixiang ^a   Pepivani, Imelda ^a   Zheng, Bin ^a   Eklund, Aron C ^a   Ney, Paul A ^c   Ng, Juliana ^d   McGoldrick, Meghan ^a   Mollenhauer, Brit ^a   Bresnick, Emery H ^b   Schlossmacher, Michael G ^a,d  

^a Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

synuclein dosage; GATA 1; GATA 2; Gene expression; Microarray

Indexed keywords

ALPHA SYNUCLEIN; HEME; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2;

ALAS2 GENE; ANIMAL CELL; ARTICLE; BLVRB GENE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ERYTHROCYTE; ERYTHROID CELL; FECH GENE; GENE; GENE EXPRESSION; GENETIC COMPLEMENTATION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; INTRON; MOUSE; NERVE CELL; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SUBSTANTIA NIGRA;

5-AMINOLEVULINATE SYNTHETASE; ALPHA-SYNUCLEIN; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GATA TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENETIC COMPLEMENTATION TEST; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICROARRAY ANALYSIS; PARKINSON DISEASE; RNA, SMALL INTERFERING;

EID: 49449102642     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802437105     Document Type: Article

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