Molecular imaging of phosphorylation events for drug development

Molecular Imaging and Biology

Volumn 11, Issue 3, 2009, Pages 144-158

  Chan, C T ^a,b   Paulmurugan, R ^a,b   Reeves, R E ^a,b   Solow Cordero, D ^a   Gambhir, S S ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Akt; Drug development; Kinases; Noninvasive; Optical bioluminescence imaging in living subjects; Phosphorylation; Repetitive imaging in living subjects

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALANINE; FIREFLY LUCIFERASE; PERIFOSINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR;

AMINO ACID SUBSTITUTION; ARTICLE; BIOLUMINESCENCE; CELL CULTURE; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFICACY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; MOLECULAR IMAGING; MONITORING; NUDE MOUSE; PRIORITY JOURNAL; SENSOR; XENOGRAFT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; DRUG DISCOVERY; GENETIC COMPLEMENTATION TEST; HUMANS; LUCIFERASES, FIREFLY; LUMINESCENCE; MICE; MOLECULAR PROBE TECHNIQUES; MOLECULAR PROBES; MUTATION; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT;

MUS MUSCULUS;

EID: 67349197831     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-008-0187-7     Document Type: Article

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