-
2
-
-
33644559031
-
Identifying cancer stem cells in solid tumors: Case not proven
-
Hill RP. Identifying cancer stem cells in solid tumors: case not proven. Cancer Res 2006; 66:1891-1895.
-
(2006)
Cancer Res
, vol.66
, pp. 1891-1895
-
-
Hill, R.P.1
-
3
-
-
0034614576
-
Stem cells: Units of development, units of regeneration, and units in evolution
-
Weissman IL. Stem cells: units of development, units of regeneration, and units in evolution. Cell 2000; 100:157-168.
-
(2000)
Cell
, vol.100
, pp. 157-168
-
-
Weissman, I.L.1
-
4
-
-
10744228523
-
Adult cardiac stem cells are multipotent and support myocardial regeneration
-
Beltrami AP, Barlucchi L, Torella D, et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003; 114:763-776.
-
(2003)
Cell
, vol.114
, pp. 763-776
-
-
Beltrami, A.P.1
Barlucchi, L.2
Torella, D.3
-
5
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim CF, Jackson EL, Woolfenden AE, et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 2005; 121:823-835.
-
(2005)
Cell
, vol.121
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
-
6
-
-
30144433093
-
Generation of a functional mammary gland from a single stem cell
-
Shackleton M, Vaillant F, Simpson KJ, et al. Generation of a functional mammary gland from a single stem cell. Nature 2006; 439:84-88.
-
(2006)
Nature
, vol.439
, pp. 84-88
-
-
Shackleton, M.1
Vaillant, F.2
Simpson, K.J.3
-
7
-
-
30144432901
-
Purification and unique properties of mammary epithelial stem cells
-
Stingl J, Eirew P, Ricketson I, et al. Purification and unique properties of mammary epithelial stem cells. Nature 2006; 439:993-997.
-
(2006)
Nature
, vol.439
, pp. 993-997
-
-
Stingl, J.1
Eirew, P.2
Ricketson, I.3
-
8
-
-
1542328965
-
Plasticity of adult stem cells
-
Wagers AJ, Weissman IL. Plasticity of adult stem cells. Cell 2004; 116:639-648.
-
(2004)
Cell
, vol.116
, pp. 639-648
-
-
Wagers, A.J.1
Weissman, I.L.2
-
9
-
-
0029958876
-
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
-
Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996; 183:1797-1806.
-
(1996)
J Exp Med
, vol.183
, pp. 1797-1806
-
-
Goodell, M.A.1
Brose, K.2
Paradis, G.3
Conner, A.S.4
Mulligan, R.C.5
-
10
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
-
Cheng T, Rodrigues N, Shen H, et al. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 2000; 287:1804-1808.
-
(2000)
Science
, vol.287
, pp. 1804-1808
-
-
Cheng, T.1
Rodrigues, N.2
Shen, H.3
-
11
-
-
2342601849
-
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
-
Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol 2004; 6:436-442.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 436-442
-
-
Yuan, Y.1
Shen, H.2
Franklin, D.S.3
Scadden, D.T.4
Cheng, T.5
-
12
-
-
27144557047
-
Perspectives on the properties of stem cells
-
McCulloch EA, Till JE. Perspectives on the properties of stem cells. Nat Med 2005; 11:1026-1028.
-
(2005)
Nat Med
, vol.11
, pp. 1026-1028
-
-
McCulloch, E.A.1
Till, J.E.2
-
13
-
-
33645469482
-
Stem cells and their niches
-
Moore KA, Lemischka IR. Stem cells and their niches. Science 2006; 311:1880-1885.
-
(2006)
Science
, vol.311
, pp. 1880-1885
-
-
Moore, K.A.1
Lemischka, I.R.2
-
14
-
-
0032567078
-
De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
-
Gat U, DasGupta R, Degenstein L, Fuchs E. De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 1998; 95:605-614.
-
(1998)
Cell
, vol.95
, pp. 605-614
-
-
Gat, U.1
DasGupta, R.2
Degenstein, L.3
Fuchs, E.4
-
15
-
-
0031848068
-
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
-
Korinek V, Barker N, Moerer P, et al. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 1998; 19:379-383.
-
(1998)
Nat Genet
, vol.19
, pp. 379-383
-
-
Korinek, V.1
Barker, N.2
Moerer, P.3
-
16
-
-
18644376279
-
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
-
Batlle E, Henderson JT, Beghtel H, et al. Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 2002; 111:251-263.
-
(2002)
Cell
, vol.111
, pp. 251-263
-
-
Batlle, E.1
Henderson, J.T.2
Beghtel, H.3
-
17
-
-
0346458662
-
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
-
Kuhnert F, Davis CR, Wang HT, et al. Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proc Natl Acad Sci USA 2004; 101:266-271.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 266-271
-
-
Kuhnert, F.1
Davis, C.R.2
Wang, H.T.3
-
18
-
-
2342427631
-
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
-
Lo Celso C, Prowse DM, Watt FM. Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development 2004; 131:1787-1799.
-
(2004)
Development
, vol.131
, pp. 1787-1799
-
-
Lo Celso, C.1
Prowse, D.M.2
Watt, F.M.3
-
19
-
-
0037829660
-
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
-
Pinto D, Gregorieff A, Begthel H, Clevers H. Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev 2003; 17:1709-1713.
-
(2003)
Genes Dev
, vol.17
, pp. 1709-1713
-
-
Pinto, D.1
Gregorieff, A.2
Begthel, H.3
Clevers, H.4
-
20
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005; 434:843-850.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
21
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
Reya T, Duncan AW, Ailles L, et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003; 423:409-414.
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
-
22
-
-
0037158748
-
Patched acts catalytically to suppress the activity of smoothened
-
Taipale J, Cooper MK, Maiti T, Beachy PA. Patched acts catalytically to suppress the activity of smoothened. Nature 2002; 418:892-897.
-
(2002)
Nature
, vol.418
, pp. 892-897
-
-
Taipale, J.1
Cooper, M.K.2
Maiti, T.3
Beachy, P.A.4
-
23
-
-
0033694305
-
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
-
Varnum-Finney B, Xu L, Brashem-Stein C, et al. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nat Med 2000; 6:1278-1281.
-
(2000)
Nat Med
, vol.6
, pp. 1278-1281
-
-
Varnum-Finney, B.1
Xu, L.2
Brashem-Stein, C.3
-
24
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert K, Brown JD, Danenberg E, et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003; 423:448-452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
-
25
-
-
20144370145
-
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
-
Duncan AW, Rattis FM, DiMascio LN, et al. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nat Immunol 2005; 6:314-322.
-
(2005)
Nat Immunol
, vol.6
, pp. 314-322
-
-
Duncan, A.W.1
Rattis, F.M.2
DiMascio, L.N.3
-
26
-
-
6944224156
-
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling
-
He XC, Zhang J, Tong WG, et al. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet 2004; 36:1117-1121.
-
(2004)
Nat Genet
, vol.36
, pp. 1117-1121
-
-
He, X.C.1
Zhang, J.2
Tong, W.G.3
-
27
-
-
0142245613
-
TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro
-
Larsson J, Blank U, Helgadottir H, et al. TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro. Blood 2003; 102:3129-3135.
-
(2003)
Blood
, vol.102
, pp. 3129-3135
-
-
Larsson, J.1
Blank, U.2
Helgadottir, H.3
-
28
-
-
33646428091
-
Normal stem cells and cancer stem cells: The niche matters
-
Li L, Neaves WB. Normal stem cells and cancer stem cells: the niche matters. Cancer Res 2006; 66:4553-4557.
-
(2006)
Cancer Res
, vol.66
, pp. 4553-4557
-
-
Li, L.1
Neaves, W.B.2
-
29
-
-
0035805055
-
Multi-organ, multilineage engraftment by a single bone marrow-derived stem cell
-
Krause DS, Theise ND, Collector MI, et al. Multi-organ, multilineage engraftment by a single bone marrow-derived stem cell. Cell 2001; 105:369-377.
-
(2001)
Cell
, vol.105
, pp. 369-377
-
-
Krause, D.S.1
Theise, N.D.2
Collector, M.I.3
-
30
-
-
0033406436
-
Hematopoietic potential of stem cells isolated from murine skeletal muscle
-
Jackson KA, Mi T, Goodell MA. Hematopoietic potential of stem cells isolated from murine skeletal muscle. Proc Natl Acad Sci USA 1999; 96:14482-14486.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14482-14486
-
-
Jackson, K.A.1
Mi, T.2
Goodell, M.A.3
-
31
-
-
0344845003
-
Epithelial-mesenchymal transitions in development and pathologies
-
Thiery JP. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 2003; 15:740-746.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 740-746
-
-
Thiery, J.P.1
-
32
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3:730-737.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
33
-
-
5444256238
-
Self-renewal and solid tumor stem cells
-
Al-Hajj M, Clarke MF. Self-renewal and solid tumor stem cells. Oncogene 2004; 23:7274-7282.
-
(2004)
Oncogene
, vol.23
, pp. 7274-7282
-
-
Al-Hajj, M.1
Clarke, M.F.2
-
34
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003; 63:5821-5828.
-
(2003)
Cancer Res
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
-
35
-
-
0344735881
-
Cancerous stem cells can arise from pediatric brain tumors
-
Hemmati HD, Nakano I, Lazareff JA, et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA 2003; 100:15178-15183.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15178-15183
-
-
Hemmati, H.D.1
Nakano, I.2
Lazareff, J.A.3
-
36
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004; 432:396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
37
-
-
33646045010
-
Stem cells and cancer: Two faces of eve
-
Clarke MF, Fuller M. Stem cells and cancer: two faces of eve. Cell 2006; 124:1111-1115.
-
(2006)
Cell
, vol.124
, pp. 1111-1115
-
-
Clarke, M.F.1
Fuller, M.2
-
38
-
-
16844378799
-
Leukaemia stem cells and the evolution of cancer-stem-cell research
-
Huntly BJ, Gilliland DG. Leukaemia stem cells and the evolution of cancer-stem-cell research. Nat Rev Cancer 2005; 5:311-321.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 311-321
-
-
Huntly, B.J.1
Gilliland, D.G.2
-
39
-
-
33644826473
-
Roots and stems: Stem cells in cancer
-
Polyak K, Hahn WC. Roots and stems: stem cells in cancer. Nat Med 2006; 12:296-300.
-
(2006)
Nat Med
, vol.12
, pp. 296-300
-
-
Polyak, K.1
Hahn, W.C.2
-
40
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001; 414:105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
41
-
-
0034687840
-
Direct isolation of human central nervous system stem cells
-
Uchida N, Buck DW, He D, et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci USA 2000; 97:14720-14725.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 14720-14725
-
-
Uchida, N.1
Buck, D.W.2
He, D.3
-
42
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003; 423:255-260.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
43
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
Park IK, Qian D, Kiel M, et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003; 423:302-305.
-
(2003)
Nature
, vol.423
, pp. 302-305
-
-
Park, I.K.1
Qian, D.2
Kiel, M.3
-
44
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky AV, Pardal R, Iwashita T, et al. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003; 425:962-967.
-
(2003)
Nature
, vol.425
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
-
45
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
-
Liu S, Dontu G, Mantle ID, et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 2006; 66:6063-6071.
-
(2006)
Cancer Res
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
-
46
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz OH, Valdez R, Theisen BK, et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 2006; 441:475-482.
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
-
47
-
-
0034691092
-
AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation
-
Miyamoto T, Weissman IL, Akashi K. AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation. Proc Natl Acad Sci USA 2000; 97:7521-7526.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7521-7526
-
-
Miyamoto, T.1
Weissman, I.L.2
Akashi, K.3
-
49
-
-
9444265320
-
Gastric cancer originating from bone marrow-derived cells
-
Houghton J, Stoicov C, Nomura S, et al. Gastric cancer originating from bone marrow-derived cells. Science 2004; 306:1568-1571.
-
(2004)
Science
, vol.306
, pp. 1568-1571
-
-
Houghton, J.1
Stoicov, C.2
Nomura, S.3
-
50
-
-
0042190662
-
Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias
-
Jaiswal S, Traver D, Miyamoto T, et al. Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias. Proc Natl Acad Sci USA 2003; 100:10002-10007.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10002-10007
-
-
Jaiswal, S.1
Traver, D.2
Miyamoto, T.3
-
51
-
-
3943088431
-
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
-
Jamieson CH, Ailles LE, Dylla SJ, et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med 2004; 351:657-667.
-
(2004)
N Engl J Med
, vol.351
, pp. 657-667
-
-
Jamieson, C.H.1
Ailles, L.E.2
Dylla, S.J.3
-
52
-
-
33746498580
-
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
-
Krivtsov AV, Twomey D, Feng Z, et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 2006; 442:818-822.
-
(2006)
Nature
, vol.442
, pp. 818-822
-
-
Krivtsov, A.V.1
Twomey, D.2
Feng, Z.3
-
54
-
-
33646556733
-
Bone marrow-derived cells fuse with normal and transformed intestinal stem cells
-
Rizvi AZ, Swain JR, Davies PS, et al. Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. ProcNatl Acad Sci USA 2006; 103:6321-6325.
-
(2006)
ProcNatl Acad Sci USA
, vol.103
, pp. 6321-6325
-
-
Rizvi, A.Z.1
Swain, J.R.2
Davies, P.S.3
-
55
-
-
85047690508
-
Opinion: The origin of the cancer stem cell: current controversies and new insights
-
Bjerkvig R, Tysnes BB, Aboody KS, Najbauer J, Terzis AJ. Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat Rev Cancer 2005; 5:899-904.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 899-904
-
-
Bjerkvig, R.1
Tysnes, B.B.2
Aboody, K.S.3
Najbauer, J.4
Terzis, A.J.5
-
56
-
-
19044397160
-
Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo RM, Maher EA, Ligon KL, et al. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 2002; 1:269-277.
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
-
57
-
-
0018102359
-
The relationship between the spleen colony-forming cell and the haemopoietic stem cell
-
Schofield R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 1978; 4:7-25.
-
(1978)
Blood Cells
, vol.4
, pp. 7-25
-
-
Schofield, R.1
-
58
-
-
28444486367
-
Stem cell niche: Structure and function
-
Li L, Xie T. Stem cell niche: structure and function. Annu Rev Cell Dev Biol 2005; 21:605-631.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 605-631
-
-
Li, L.1
Xie, T.2
-
59
-
-
33745635043
-
The stem-cell niche as an entity of action
-
Scadden DT. The stem-cell niche as an entity of action. Nature 2006; 441:1075-1079.
-
(2006)
Nature
, vol.441
, pp. 1075-1079
-
-
Scadden, D.T.1
-
60
-
-
0034644602
-
A niche maintaining germ line stem cells in the Drosophila ovary
-
Xie T, Spradling AC. A niche maintaining germ line stem cells in the Drosophila ovary. Science 2000; 290:328-330.
-
(2000)
Science
, vol.290
, pp. 328-330
-
-
Xie, T.1
Spradling, A.C.2
-
61
-
-
0036894182
-
The stem-cell niche theory: Lessons from flies
-
Lin H. The stem-cell niche theory: lessons from flies. Nat Rev Genet 2002; 3:931-940.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 931-940
-
-
Lin, H.1
-
62
-
-
0035930669
-
Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue
-
Kiger AA, Jones DL, Schulz C, Rogers MB, Fuller MT. Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue. Science 2001; 294:2542-2545.
-
(2001)
Science
, vol.294
, pp. 2542-2545
-
-
Kiger, A.A.1
Jones, D.L.2
Schulz, C.3
Rogers, M.B.4
Fuller, M.T.5
-
63
-
-
3142739470
-
A misexpression screen reveals effects of bag-of-marbles and TGF beta class signaling on the Drosophila male germ-line stem cell lineage
-
Schulz C, Kiger AA, Tazuke SI, et al. A misexpression screen reveals effects of bag-of-marbles and TGF beta class signaling on the Drosophila male germ-line stem cell lineage. Genetics 2004; 167:707-723.
-
(2004)
Genetics
, vol.167
, pp. 707-723
-
-
Schulz, C.1
Kiger, A.A.2
Tazuke, S.I.3
-
64
-
-
1842559510
-
Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary
-
Song X, Wong MD, Kawase E, et al. Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary. Development 2004; 131:1353-1364.
-
(2004)
Development
, vol.131
, pp. 1353-1364
-
-
Song, X.1
Wong, M.D.2
Kawase, E.3
-
65
-
-
0035930688
-
Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling
-
Tulina N, Matunis E. Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling. Science 2001; 294:2546-2549.
-
(2001)
Science
, vol.294
, pp. 2546-2549
-
-
Tulina, N.1
Matunis, E.2
-
66
-
-
0032563165
-
Decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary
-
Xie T, Spradling AC. Decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell 1998; 94:251-260.
-
(1998)
Cell
, vol.94
, pp. 251-260
-
-
Xie, T.1
Spradling, A.C.2
-
67
-
-
33745600820
-
Asymmetric and symmetric stem-cell divisions in development and cancer
-
Morrison SJ, Kimble J. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 2006; 441:1068-1074.
-
(2006)
Nature
, vol.441
, pp. 1068-1074
-
-
Morrison, S.J.1
Kimble, J.2
-
68
-
-
0242268524
-
Osteoblastic cells regulate the haematopoietic stem cell niche
-
Calvi LM, Adams GB, Weibrecht KW, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003; 425:841-846.
-
(2003)
Nature
, vol.425
, pp. 841-846
-
-
Calvi, L.M.1
Adams, G.B.2
Weibrecht, K.W.3
-
69
-
-
0242363225
-
Identification of the haematopoietic stem cell niche and control of the niche size
-
Zhang J, Niu C, Ye L, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003; 425:836-841.
-
(2003)
Nature
, vol.425
, pp. 836-841
-
-
Zhang, J.1
Niu, C.2
Ye, L.3
-
70
-
-
21344474104
-
Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
-
Nilsson SK, Johnston HM, Whitty GA, et al. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 2005; 106:1232-1239.
-
(2005)
Blood
, vol.106
, pp. 1232-1239
-
-
Nilsson, S.K.1
Johnston, H.M.2
Whitty, G.A.3
-
71
-
-
21244472780
-
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
-
Stier S, Ko Y, Forkert R, et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med 2005; 201:1781-1791.
-
(2005)
J Exp Med
, vol.201
, pp. 1781-1791
-
-
Stier, S.1
Ko, Y.2
Forkert, R.3
-
72
-
-
0035524455
-
The functional and clinical roles of osteopontin in cancer and metastasis
-
Furger KA, Menon RK, Tuck AB, Bramwell VH, Chambers AF. The functional and clinical roles of osteopontin in cancer and metastasis. Curr Mol Med 2001; 1:621-632.
-
(2001)
Curr Mol Med
, vol.1
, pp. 621-632
-
-
Furger, K.A.1
Menon, R.K.2
Tuck, A.B.3
Bramwell, V.H.4
Chambers, A.F.5
-
73
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003; 3:537-549.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
-
74
-
-
33646165532
-
Notch, epidermal growth factor receptor, and beta1-integrin pathways are coordinated in neural stem cells
-
Campos LS, Decker L, Taylor V, Skarnes W. Notch, epidermal growth factor receptor, and beta1-integrin pathways are coordinated in neural stem cells. J Biol Chem 2006; 281:5300-5309.
-
(2006)
J Biol Chem
, vol.281
, pp. 5300-5309
-
-
Campos, L.S.1
Decker, L.2
Taylor, V.3
Skarnes, W.4
-
75
-
-
1642603951
-
Socializing with the neighbors: Stem cells and their niche
-
Fuchs E, Tumbar T, Guasch G. Socializing with the neighbors: stem cells and their niche. Cell 2004; 116:769-778.
-
(2004)
Cell
, vol.116
, pp. 769-778
-
-
Fuchs, E.1
Tumbar, T.2
Guasch, G.3
-
76
-
-
0029991362
-
Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins
-
Hirsch E, Iglesias A, Potocnik AJ, Hartmann U, Fassler R. Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins. Nature 1996; 380:171-175.
-
(1996)
Nature
, vol.380
, pp. 171-175
-
-
Hirsch, E.1
Iglesias, A.2
Potocnik, A.J.3
Hartmann, U.4
Fassler, R.5
-
77
-
-
9644254219
-
p51/p63 controls subunit alpha3 of the major epidermis integrin anchoring the stem cells to the niche
-
Kurata S, Okuyama T, Osada M, et al. p51/p63 controls subunit alpha3 of the major epidermis integrin anchoring the stem cells to the niche. J Biol Chem 2004; 279:50069-50077.
-
(2004)
J Biol Chem
, vol.279
, pp. 50069-50077
-
-
Kurata, S.1
Okuyama, T.2
Osada, M.3
-
78
-
-
0034712109
-
Out of Eden: Stem cells and their niches
-
Watt FM, Hogan BL. Out of Eden: stem cells and their niches. Science 2000; 287:1427-1430.
-
(2000)
Science
, vol.287
, pp. 1427-1430
-
-
Watt, F.M.1
Hogan, B.L.2
-
79
-
-
8644219660
-
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
-
Wilson A, Murphy MJ, Oskarsson T, et al. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev 2004; 18:2747-2763.
-
(2004)
Genes Dev
, vol.18
, pp. 2747-2763
-
-
Wilson, A.1
Murphy, M.J.2
Oskarsson, T.3
-
80
-
-
3242669145
-
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
-
Arai F, Hirao A, Ohmura M, et al. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 2004; 118:149-161.
-
(2004)
Cell
, vol.118
, pp. 149-161
-
-
Arai, F.1
Hirao, A.2
Ohmura, M.3
-
81
-
-
1942457308
-
Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
-
Visnjic D, Kalajzic Z, Rowe DW, et al. Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. Blood 2004; 103:3258-3264.
-
(2004)
Blood
, vol.103
, pp. 3258-3264
-
-
Visnjic, D.1
Kalajzic, Z.2
Rowe, D.W.3
-
82
-
-
21244463426
-
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
-
Kiel MJ, Yilmaz OH, Iwashita T, et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005; 121:1109-1121.
-
(2005)
Cell
, vol.121
, pp. 1109-1121
-
-
Kiel, M.J.1
Yilmaz, O.H.2
Iwashita, T.3
-
83
-
-
21244450283
-
Stem cell grand SLAM
-
Wagers AJ. Stem cell grand SLAM. Cell 2005; 121:967-970.
-
(2005)
Cell
, vol.121
, pp. 967-970
-
-
Wagers, A.J.1
-
84
-
-
11144356721
-
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
-
Avecilla ST, Hattori K, Heissig B, et al. Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nat Med 2004; 10:64-71.
-
(2004)
Nat Med
, vol.10
, pp. 64-71
-
-
Avecilla, S.T.1
Hattori, K.2
Heissig, B.3
-
85
-
-
33646435309
-
The stem cell niches in bone
-
Yin T, Li L. The stem cell niches in bone. J Clin Invest 2006; 116:1195-1201.
-
(2006)
J Clin Invest
, vol.116
, pp. 1195-1201
-
-
Yin, T.1
Li, L.2
-
86
-
-
1442357036
-
Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization
-
Papayannopoulou T. Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization. Blood 2004; 103:1580-1585.
-
(2004)
Blood
, vol.103
, pp. 1580-1585
-
-
Papayannopoulou, T.1
-
87
-
-
33749349596
-
The metastasis-associated 67 kDa laminin receptor is involved in G-CSF-induced hematopoietic stem cell mobilization
-
Selleri C, Ragno P, Ricci P, et al. The metastasis-associated 67 kDa laminin receptor is involved in G-CSF-induced hematopoietic stem cell mobilization. Blood 2006; 108:2476-2484.
-
(2006)
Blood
, vol.108
, pp. 2476-2484
-
-
Selleri, C.1
Ragno, P.2
Ricci, P.3
-
88
-
-
0031026475
-
The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood
-
Aiuti A, Webb IJ, Bleul C, Springer T, Gutierrez-Ramos JC. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med 1997; 185:111-120.
-
(1997)
J Exp Med
, vol.185
, pp. 111-120
-
-
Aiuti, A.1
Webb, I.J.2
Bleul, C.3
Springer, T.4
Gutierrez-Ramos, J.C.5
-
89
-
-
20944440068
-
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist
-
Broxmeyer HE, Orschell CM, Clapp DW, et al. Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med 2005; 201:1307-1318.
-
(2005)
J Exp Med
, vol.201
, pp. 1307-1318
-
-
Broxmeyer, H.E.1
Orschell, C.M.2
Clapp, D.W.3
-
90
-
-
0036800296
-
The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice
-
Lapidot T, Kollet O. The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice. Leukemia 2002; 16:1992-2003.
-
(2002)
Leukemia
, vol.16
, pp. 1992-2003
-
-
Lapidot, T.1
Kollet, O.2
-
91
-
-
0033524834
-
Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
-
Peled A, Petit I, Kollet O, et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 1999; 283:845-848.
-
(1999)
Science
, vol.283
, pp. 845-848
-
-
Peled, A.1
Petit, I.2
Kollet, O.3
-
92
-
-
0037029654
-
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines
-
Wright DE, Bowman EP, Wagers AJ, Butcher EC, Weissman IL. Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med 2002; 195:1145-1154.
-
(2002)
J Exp Med
, vol.195
, pp. 1145-1154
-
-
Wright, D.E.1
Bowman, E.P.2
Wagers, A.J.3
Butcher, E.C.4
Weissman, I.L.5
-
93
-
-
0035282610
-
An attractive force in metastasis
-
Liotta LA. An attractive force in metastasis. Nature 2001; 410:24-25.
-
(2001)
Nature
, vol.410
, pp. 24-25
-
-
Liotta, L.A.1
-
94
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001; 410:50-56.
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
-
95
-
-
0035856010
-
Chemokines and the molecular basis of cancer metastasis
-
Murphy PM. Chemokines and the molecular basis of cancer metastasis. N Engl J Med 2001; 345:833-835.
-
(2001)
N Engl J Med
, vol.345
, pp. 833-835
-
-
Murphy, P.M.1
-
96
-
-
0942301172
-
Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells
-
Fernandis AZ, Prasad A, Band H, Klosel R, Ganju RK. Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells. Oncogene 2004; 23:157-167.
-
(2004)
Oncogene
, vol.23
, pp. 157-167
-
-
Fernandis, A.Z.1
Prasad, A.2
Band, H.3
Klosel, R.4
Ganju, R.K.5
-
97
-
-
9244234390
-
CXCR4 regulates growth of both primary and metastatic breast cancer
-
Smith MC, Luker KE, Garbow JR, et al. CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res 2004; 64:8604-8612.
-
(2004)
Cancer Res
, vol.64
, pp. 8604-8612
-
-
Smith, M.C.1
Luker, K.E.2
Garbow, J.R.3
-
98
-
-
0141716853
-
Cancer: Cues for migration
-
Bernards R. Cancer: cues for migration. Nature 2003; 425:247-248.
-
(2003)
Nature
, vol.425
, pp. 247-248
-
-
Bernards, R.1
-
99
-
-
7944223780
-
Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis
-
Li YM, Pan Y, Wei Y, et al. Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis. Cancer Cell 2004; 6:459-469.
-
(2004)
Cancer Cell
, vol.6
, pp. 459-469
-
-
Li, Y.M.1
Pan, Y.2
Wei, Y.3
-
100
-
-
3042616145
-
Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4
-
Liang Z, Wu T, Lou H, et al. Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Res 2004; 64:4302-4308.
-
(2004)
Cancer Res
, vol.64
, pp. 4302-4308
-
-
Liang, Z.1
Wu, T.2
Lou, H.3
-
101
-
-
0034956272
-
The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis
-
John A, Tuszynski G. The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis. Pathol Oncol Res 2001; 7:14-23.
-
(2001)
Pathol Oncol Res
, vol.7
, pp. 14-23
-
-
John, A.1
Tuszynski, G.2
-
102
-
-
0036831559
-
Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
-
Rafii S, Lyden D, Benezra R, Hattori K, Heissig B. Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? Nat Rev Cancer 2002; 2:826-835.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 826-835
-
-
Rafii, S.1
Lyden, D.2
Benezra, R.3
Hattori, K.4
Heissig, B.5
-
103
-
-
25444473106
-
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
-
Pratap J, Javed A, Languino LR, et al. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol 2005; 25:8581-8591.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8581-8591
-
-
Pratap, J.1
Javed, A.2
Languino, L.R.3
-
104
-
-
29344451650
-
CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: The role of bone microenvironment-associated CXCL12
-
Chinni SR, Sivalogan S, Dong Z, et al. CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12. Prostate 2006; 66:32-48.
-
(2006)
Prostate
, vol.66
, pp. 32-48
-
-
Chinni, S.R.1
Sivalogan, S.2
Dong, Z.3
-
105
-
-
18444389451
-
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
-
Heissig B, Hattori K, Dias S, et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 2002; 109:625-637.
-
(2002)
Cell
, vol.109
, pp. 625-637
-
-
Heissig, B.1
Hattori, K.2
Dias, S.3
-
106
-
-
0033790663
-
Differential MMP and TIMP production by human marrow and peripheral blood CD34(+) cells in response to chemokines
-
Janowska-Wieczorek A, Marquez LA, Dobrowsky A, Ratajczak MZ, Cabuhat ML. Differential MMP and TIMP production by human marrow and peripheral blood CD34(+) cells in response to chemokines. Exp Hematol 2000; 28:1274-1285.
-
(2000)
Exp Hematol
, vol.28
, pp. 1274-1285
-
-
Janowska-Wieczorek, A.1
Marquez, L.A.2
Dobrowsky, A.3
Ratajczak, M.Z.4
Cabuhat, M.L.5
-
107
-
-
85047690740
-
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
-
Kollet O, Shivtiel S, Chen YQ, et al. HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver. J Clin Invest 2003; 112:160-169.
-
(2003)
J Clin Invest
, vol.112
, pp. 160-169
-
-
Kollet, O.1
Shivtiel, S.2
Chen, Y.Q.3
-
109
-
-
31844449374
-
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor
-
Adams GB, Chabner KT, Alley IR, et al. Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature 2006; 439:599-603.
-
(2006)
Nature
, vol.439
, pp. 599-603
-
-
Adams, G.B.1
Chabner, K.T.2
Alley, I.R.3
-
110
-
-
33646820680
-
Expression of the calcium receptor in human breast cancer - a potential new marker predicting the risk of bone metastases
-
Mihai R, Stevens J, McKinney C, Ibrahim NB. Expression of the calcium receptor in human breast cancer - a potential new marker predicting the risk of bone metastases. Eur J Surg Oncol 2006; 32:511-515.
-
(2006)
Eur J Surg Oncol
, vol.32
, pp. 511-515
-
-
Mihai, R.1
Stevens, J.2
McKinney, C.3
Ibrahim, N.B.4
-
111
-
-
33749528535
-
Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation
-
Sneddon JB, Zhen HH, Montgomery K, et al. Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proc Natl Acad Sci USA 2006; 103:14842-14847.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14842-14847
-
-
Sneddon, J.B.1
Zhen, H.H.2
Montgomery, K.3
-
113
-
-
25844508786
-
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
-
Gupta PB, Kuperwasser C, Brunet JP, et al. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet 2005; 37:1047-1054.
-
(2005)
Nat Genet
, vol.37
, pp. 1047-1054
-
-
Gupta, P.B.1
Kuperwasser, C.2
Brunet, J.P.3
-
115
-
-
19044391072
-
Gene expression correlates of clinical prostate cancer behavior
-
Singh D, Febbo PG, Ross K, et al. Gene expression correlates of clinical prostate cancer behavior. Cancer Cell 2002; 1:203-209.
-
(2002)
Cancer Cell
, vol.1
, pp. 203-209
-
-
Singh, D.1
Febbo, P.G.2
Ross, K.3
-
116
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002; 415:530-536.
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
van't Veer, L.J.1
Dai, H.2
van de Vijver, M.J.3
-
117
-
-
0024708518
-
The distribution of secondary growths in cancer of the breast. 1889
-
Paget S. The distribution of secondary growths in cancer of the breast. 1889. Cancer Metastasis Rev 1989; 8:98-101.
-
(1989)
Cancer Metastasis Rev
, vol.8
, pp. 98-101
-
-
Paget, S.1
-
118
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn AJ, Gupta GP, Siegel PM, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005; 436:518-524.
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
-
119
-
-
13444268127
-
Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors
-
Minn AJ, Kang Y, Serganova I, et al. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J Clin Invest 2005; 115:44-55.
-
(2005)
J Clin Invest
, vol.115
, pp. 44-55
-
-
Minn, A.J.1
Kang, Y.2
Serganova, I.3
-
120
-
-
18844419736
-
Functional genomic analysis of cancer metastasis: Biologic insights and clinical implications
-
Kang Y. Functional genomic analysis of cancer metastasis: biologic insights and clinical implications. Expert Rev Mol Diagn 2005; 5:385-395.
-
(2005)
Expert Rev Mol Diagn
, vol.5
, pp. 385-395
-
-
Kang, Y.1
-
121
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005; 438:820-827.
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
-
122
-
-
0022479536
-
Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell
-
Fidler IJ, Talmadge JE. Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell. Cancer Res 1986; 46:5167-5171.
-
(1986)
Cancer Res
, vol.46
, pp. 5167-5171
-
-
Fidler, I.J.1
Talmadge, J.E.2
-
123
-
-
28244472139
-
Is the hypoxia-inducible factor pathway important in gastric cancer?
-
Griffiths EA, Pritchard SA, Welch IM, Price PM, West CM. Is the hypoxia-inducible factor pathway important in gastric cancer? Eur J Cancer 2005; 41:2792-2805.
-
(2005)
Eur J Cancer
, vol.41
, pp. 2792-2805
-
-
Griffiths, E.A.1
Pritchard, S.A.2
Welch, I.M.3
Price, P.M.4
West, C.M.5
-
124
-
-
33645668431
-
Chemokine receptors in head and neck cancer: Association with metastatic spread and regulation during chemotherapy
-
Muller A, Sonkoly E, Eulert C, et al. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer 2006; 118:2147-2157.
-
(2006)
Int J Cancer
, vol.118
, pp. 2147-2157
-
-
Muller, A.1
Sonkoly, E.2
Eulert, C.3
-
125
-
-
11144280033
-
Oxidative stress and cyclooxygenase activity in prostate carcinogenesis: Targets for chemopreventive strategies
-
Pathak SK, Sharma RA, Steward WP, et al. Oxidative stress and cyclooxygenase activity in prostate carcinogenesis: targets for chemopreventive strategies. Eur J Cancer 2005; 41:61-70.
-
(2005)
Eur J Cancer
, vol.41
, pp. 61-70
-
-
Pathak, S.K.1
Sharma, R.A.2
Steward, W.P.3
-
126
-
-
33845317573
-
-
Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006.
-
Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006.
-
-
-
-
129
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005; 5:275-284.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
130
-
-
0026576937
-
Isolation of a candidate human hematopoietic stem-cell population
-
Baum CM, Weissman IL, Tsukamoto AS, Buckle AM, Peault B. Isolation of a candidate human hematopoietic stem-cell population. Proc Natl Acad Sci USA 1992; 89:2804-2808.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2804-2808
-
-
Baum, C.M.1
Weissman, I.L.2
Tsukamoto, A.S.3
Buckle, A.M.4
Peault, B.5
-
131
-
-
0025732159
-
Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells
-
Terstappen LW, Huang S, Safford M, Lansdorp PM, Loken MR. Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells. Blood 1991; 77:1218-1227.
-
(1991)
Blood
, vol.77
, pp. 1218-1227
-
-
Terstappen, L.W.1
Huang, S.2
Safford, M.3
Lansdorp, P.M.4
Loken, M.R.5
-
132
-
-
9444269823
-
Highly purified CD34-positive cells reconstitute hematopoiesis
-
Civin CI, Trischmann T, Kadan NS, et al. Highly purified CD34-positive cells reconstitute hematopoiesis. J Clin Oncol 1996; 14:2224-2233.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2224-2233
-
-
Civin, C.I.1
Trischmann, T.2
Kadan, N.S.3
-
133
-
-
0032100437
-
In vitro identification of single CD34+CD38- cells with both lymphoid and myeloid potential
-
Hao QL, Smogorzewska EM, Barsky LW, Crooks GM. In vitro identification of single CD34+CD38- cells with both lymphoid and myeloid potential. Blood 1998; 91:4145-4151.
-
(1998)
Blood
, vol.91
, pp. 4145-4151
-
-
Hao, Q.L.1
Smogorzewska, E.M.2
Barsky, L.W.3
Crooks, G.M.4
-
134
-
-
0026502896
-
Searching for hematopoietic stem cells: Evidence that Thy-1.1lo Lin-Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow
-
Uchida N, Weissman IL. Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin-Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow. J Exp Med 1992; 175:175-184.
-
(1992)
J Exp Med
, vol.175
, pp. 175-184
-
-
Uchida, N.1
Weissman, I.L.2
-
135
-
-
0026500983
-
Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation
-
Ikuta K, Weissman IL. Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proc Natl Acad Sci USA 1992; 89:1502-1506.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1502-1506
-
-
Ikuta, K.1
Weissman, I.L.2
-
137
-
-
27144557960
-
A tumorigenic subpopulation with stem cell properties in melanomas
-
Fang D, Nguyen TK, Leishear K, et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Research 2005; 65:9328-9337.
-
(2005)
Cancer Research
, vol.65
, pp. 9328-9337
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
-
138
-
-
4444262529
-
CD133, a novel marker for human prostatic epithelial stem cells
-
Richardson GD, Robson CN, Lang SH, et al. CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci 2004; 117:3539- 3545.
-
(2004)
J Cell Sci
, vol.117
, pp. 3539-3545
-
-
Richardson, G.D.1
Robson, C.N.2
Lang, S.H.3
-
139
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005; 65:10946-10951.
-
(2005)
Cancer Res
, vol.65
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
|