Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

Nature

Volumn 461, Issue 7265, 2009, Pages 809-813

  Shah, Sohrab P ^a   Morin, Ryan D ^a   Khattra, Jaswinder ^a   Prentice, Leah ^a   Pugh, Trevor ^a   Burleigh, Angela ^a   Delaney, Allen ^a   Gelmon, Karen ^a   Guliany, Ryan ^a   Senz, Janine ^a   Steidl, Christian ^a,b   Holt, Robert A ^a   Jones, Steven ^a   Sun, Mark ^a   Leung, Gillian ^a   Moore, Richard ^a   Severson, Tesa ^a   Taylor, Greg A ^a   Teschendorff, Andrew E ^c   Tse, Kane ^a   Turashvili, Gulisa ^a   Varhol, Richard ^a   Warren, René L ^a   Watson, Peter ^a   Zhao, Yongjun ^a   Caldas, Carlos ^c   Huntsman, David ^a,b   Hirst, Martin ^a   Marra, Marco A ^a   Aparicio, Samuel ^a,b   more..

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR;

CANCER; CYTOLOGY; DISEASE INCIDENCE; ESTROGENIC COMPOUND; GENETIC ANALYSIS; GENOMICS; MUTATION; RNA; TUMOR;

ARTICLE; BREAST CANCER; DNA SEQUENCE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; METASTASIS; POINT MUTATION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; BREAST NEOPLASMS; DISEASE PROGRESSION; DNA MUTATIONAL ANALYSIS; ESTROGEN RECEPTOR ALPHA; EVOLUTION, MOLECULAR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; GENOME, HUMAN; GERM-LINE MUTATION; HUMANS; MUTAGENESIS; MUTATION; NEOPLASM METASTASIS; NUCLEOTIDES; RNA EDITING; SIGNAL RECOGNITION PARTICLE; TIME FACTORS;

EID: 70349969478     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08489     Document Type: Article

References (19)

1. Campbell, P. J. et al. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nature Genet. 40, 722-729 (2008).
2. Bentley, D. R. et al. Accurate whole human genome sequencing using reversible terminator chemistry. Nature 456, 53-59 (2008).
3. Morin, R. et al. Profiling the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing. Biotechniques 45, 81-94 (2008).
4. Ley, T. J. et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 456, 66-72 (2008).
5. Mortazavi, A., Williams, B. A., McCue, K., Schaeffer, L. & Wold, B. Mapping and quantifying mammalian transcripomes by RNA-Seq. Nature Methods 5, 621-628 (2008).
6. Wood, L. D. et al. The genomic landscapes of human breast and colorectal cancers. Science 318, 1108-1113 (2007).
7. Forbes, S. A. et al. The Catalogue of Somatic Mutations in Cancer (COSMIC). Curr. Protoc. Hum. Genet. Unit 10.11, doi:10.1002/0471142905.hg1011s57 (2008).
8. Goshima, G., Mayer, M., Zhang, N., Stuurman, N. & Vale, R. D. Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. J. Cell Biol. 181, 421-429 (2008).
9. Meireles, A. M., Fisher, K. H., Colombie, N., Wakefield, J. G. & Ohkura, H. Wac: a new Augmin subunit required for chromosome alignment but not for acentrosomal microtubule assembly in female meiosis. J. Cell Biol. 184, 777-784 (2009).
10. Lawo, S. et al. HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr. Biol. 19, 816-826 (2009).
11. Pauklin, S., Sernandez, I. V., Bachmann, G., Ramiro, A. R. & Petersen-Mahrt, S. K. Estrogen directly activates AID transcription and function. J. Exp. Med. 206, 99-111 (2009).
12. Blow, M., Futreal, P. A., Wooster, R. & Stratton, M. R. A survey of RNA editing in human brain. Genome Res. 14, 2379-2387 (2004).
13. Athanasiadis, A., Rich, A. & Maas, S. Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome. PLoS Biol. 2, e391 (2004).
14. Maas, S., Kawahara, Y., Tamburro, K. M. & Nishikura, K. A-to-I RNA editing and human disease. RNA Biol. 3, 1-9 (2006).
15. Li, J. B. et al. Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing. Science 324, 1210-1213 (2009).
16. Greenman, C. et al. Patterns of somatic mutation in human cancer genomes. Nature 446, 153-158 (2007).
17. Li, H., Ruan, J. & Durbin, R. Mapping short DNA sequencing reads and calling variants using mapping quality scores. Genome Res. 18, 1851-1858 (2008).
18. Wang, J. et al. The diploid genome sequence of an Asian individual. Nature 456, 60-65 (2008).
19. Wheeler, D. A. et al. The complete genome of an individual by massively parallel DNA sequencing. Nature 452, 872-876 (2008).