In vivo selection for metastasis promoting genes in the mouse

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 16, 2007, Pages 6696-6701

  Gumireddy, Kiranmai ^a   Sun, Fangxian ^b   Klein Szanto, Andres J ^c   Gibbins, Jonathan M ^d   Gimotty, Phyllis A ^e   Saunders, Aleister J ^f   Schultz, Peter G ^b,g   Huang, Qihong ^a  

^a WISTAR INSTITUTE   (United States)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^c FOX CHASE CANCER CENTER   (United States)

^d UNIVERSITY OF READING   (United Kingdom)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f DREXEL UNIVERSITY   (United States)

^g SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Breast cancer invasion and metastasis; Disulfide isomerase ERp5; ErbB2 phosphoinosftide 3 kinase; Forward genetic screen; Orthotopic animal model

Indexed keywords

BETA CATENIN; COMPLEMENTARY DNA; DISULFIDE ISOMERASE ERP5; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ISOMERASE; PHOSPHATIDYLINOSITOL 3 KINASE; RETROVIRUS VECTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; PDIA6 PROTEIN, HUMAN; PROTEIN DISULFIDE ISOMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT; BREAST CANCER; CANCER CELL CULTURE; CANCER INVASION; CATALYSIS; CELL MIGRATION; CONTROLLED STUDY; DIMERIZATION; DISULFIDE BOND; DNA LIBRARY; GENE OVEREXPRESSION; GENETIC SCREENING; HUMAN; HUMAN TISSUE; ISOMERIZATION; METASTASIS; MOUSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; REDUCTION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ENZYMOLOGY; EXPERIMENTAL NEOPLASM; FEMALE; GENETIC SELECTION; GENETICS; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALIA; MUS;

ANIMALS; CELL LINE, TUMOR; FEMALE; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MICE; PROTEIN DISULFIDE-ISOMERASE; SELECTION (GENETICS);

EID: 34249847158     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0701145104     Document Type: Article

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