Normal mode gating motions of a ligand-gated ion channel persist in a fully hydrated lipid bilayer model

ACS Chemical Neuroscience

Volumn 1, Issue 8, 2010, Pages 552-558

  Bertaccini, Edward J ^a,b   Trudell, James R ^a   Lindahl, Erik ^c  

^a STANFORD UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

anesthetic mechanism; elastic network model; glycine 1 receptor; ligand gated ion channels; lipid bilayer; Normal mode analysis

Indexed keywords

GLYCINE ALPHA 1 RECEPTOR; GLYCINE RECEPTOR; ION CHANNEL; LIPID; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; WATER;

ARTICLE; CHANNEL GATING; HYDRATION; MOLECULAR MODEL; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; VIBRATION;

ANESTHETIC MECHANISM; ELASTIC NETWORK MODEL; GLYCINE Α-1 RECEPTOR; LIGAND-GATED ION CHANNELS; LIPID BILAYER; NORMAL-MODE ANALYSIS;

COMPUTER SIMULATION; HUMANS; ION CHANNEL GATING; LIPID BILAYERS; MODELS, MOLECULAR; MOTION; PROTEIN CONFORMATION; RECEPTORS, GLYCINE; VIBRATION; WATER;

EID: 77955897919     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn100026t     Document Type: Article

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