Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol

European Journal of Pain

Volumn 12, Issue 4, 2008, Pages 441-454

  Vetter, Irina ^a   Wyse, Bruce D ^a   Roberts Thomson, Sarah J ^a   Monteith, Gregory R ^a   Cabot, Peter J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Ethanol; Morphine; PIP2; PKA; TRPV1

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ALCOHOL; CAPSAICIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MORPHINE; MU OPIATE RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POLO LIKE KINASE; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; VANILLOID RECEPTOR 1; WORTMANNIN;

ALCOHOL OXIDATION; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; EMBRYO; ENZYME INDUCTION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYPERALGESIA; NOCICEPTION; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; SENSITIZATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETALDEHYDE; ANALGESICS, OPIOID; CALCIUM; CAPSAICIN; CELL LINE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DITERPENES; DRUG SYNERGISM; ESTRENES; ETHANOL; HUMANS; ION CHANNEL GATING; KIDNEY; MORPHINE; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHODIESTERASE INHIBITORS; PROTEIN KINASE C; PYRROLIDINONES; RADIOLIGAND ASSAY; SENSORY SYSTEM AGENTS; TRITIUM; TRPV CATION CHANNELS;

EID: 39749183495     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2007.07.001     Document Type: Article

References (69)

1. Amaya F., Shimosato G., Nagano M., Ueda M., Hashimoto S., Tanaka Y., et al. NGF and GDNF differentially regulate TRPV1 expression that contributes to development of inflammatory thermal hyperalgesia. Eur J Neurosci 20 (2004) 2303-2310
2. Amstrup J., and Novak I. P2X7 receptor activates extracellular signal-regulated kinases ERK1 and ERK2 independently of Ca2+ influx. Biochem J 374 (2003) 51-61
3. Asyyed A., Storm D., and Diamond I. Ethanol activates cAMP response element-mediated gene expression in select regions of the mouse brain. Brain Res 1106 (2006) 63-71
4. Beghi E., and Monticelli M.L. Chronic symmetric symptomatic polyneuropathy in the elderly: a field screening investigation of risk factors for polyneuropathy in two Italian communities. Italian General Practitioner Study Group (IGPST). J Clin Epidemiol 51 (1998) 697-702
5. Benedikt J., Teisinger J., Vyklicky L., and Vlachova V. Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate. J Neurochem 100 (2007) 211-224
6. Bleasdale J.E., Thakur N.R., Gremban R.S., Bundy G.L., Fitzpatrick F.A., Smith R.J., et al. Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils. J Pharmacol Exp Ther 255 (1990) 756-768
7. Bonnington J.K., and McNaughton P.A. Signalling pathways involved in the sensitisation of mouse nociceptive neurones by nerve growth factor. J Physiol 551 (2003) 433-446
8. Caterina M.J., Leffler A., Malmberg A.B., Martin W.J., Trafton J., Petersen-Zeitz K.R., et al. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288 (2000) 306-313
9. Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., and Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389 (1997) 816-824
10. Charness M.E., Querimit L.A., and Diamond I. Ethanol increases the expression of functional delta-opioid receptors in neuroblastoma x glioma NG108-15 hybrid cells. J Biol Chem 261 (1986) 3164-3169
11. Cho H., Hwang J.Y., Kim D., Shin H.S., Kim Y., Earm Y.E., et al. Acetylcholine-induced phosphatidylinositol 4,5-bisphosphate depletion does not cause short-term desensitization of G protein-gated inwardly rectifying K+ current in mouse atrial myocytes. J Biol Chem 277 (2002) 27742-27747
12. Chuang H.H., Prescott E.D., Kong H., Shields S., Jordt S.E., Basbaum A.I., et al. Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature 411 (2001) 957-962
13. Davis J.B., Gray J., Gunthorpe M.J., Hatcher J.P., Davey P.T., Overend P., et al. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 405 (2000) 183-187
14. Dina O.A., Gear R.W., Messing R.O., and Levine J.D. Severity of alcohol-induced painful peripheral neuropathy in female rats: role of estrogen and protein kinase (A and Cepsilon). Neuroscience 145 (2007) 350-356
15. Dohrman D.P., Chen H.M., Gordon A.S., and Diamond I. Ethanol-induced translocation of protein kinase A occurs in two phases: control by different molecular mechanisms. Alcohol Clin Exp Res 26 (2002) 407-415
16. Dohrman D.P., Diamond I., and Gordon A.S. Ethanol causes translocation of cAMP-dependent protein kinase catalytic subunit to the nucleus. Proc Natl Acad Sci USA 93 (1996) 10217-10221
17. Feisst C., Albert D., Steinhilber D., and Werz O. The aminosteroid phospholipase C antagonist U-73122 (1-[6-[[17-beta-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H- pyrrole-2,5-dione) potently inhibits human 5-lipoxygenase in vivo and in vitro. Mol Pharmacol 67 (2005) 1751-1757
18. Ferby I., Waga I., Kume K., Sakanaka C., and Shimizu T. PAF-induced MAPK activation is inhibited by wortmannin in neutrophils and macrophages. Adv Exp Med Biol 416 (1996) 321-326
19. Gavva N.R., Tamir R., Qu Y., Klionsky L., Zhang T.J., Immke D., et al. AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties. J Pharmacol Exp Ther 313 (2005) 474-484
20. Harada S., Agarwal D.P., Goedde H.W., and Takagi S. Blood ethanol and acetaldehyde levels in Japanese alcoholics and controls. Pharmacol Biochem Behav 18 Suppl 1 (1983) 139-140
21. Hong S., and Wiley J. Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1. J Biol Chem 280 (2005) 618-627
22. Ji R.R., Samad T.A., Jin S.X., Schmoll R., and Woolf C.J. p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 36 (2002) 57-68
23. Jiang Z.L., and Ye J.H. Protein kinase C epsilon is involved in ethanol potentiation of glycine-gated Cl(-) current in rat neurons of ventral tegmental area. Neuropharmacology 44 (2003) 493-502
24. Jones A.W., and Holmgren P. Comparison of blood-ethanol concentration in deaths attributed to acute alcohol poisoning and chronic alcoholism. J Forensic Sci 48 (2003) 874-879
25. Koike H., and Sobue G. Alcoholic neuropathy. Curr Opin Neurol 19 (2006) 481-486
26. Liu B., Zhang C., and Qin F. Functional recovery from desensitization of vanilloid receptor TRPV1 requires resynthesis of phosphatidylinositol 4,5-bisphosphate. J Neurosci 25 (2005) 4835-4843
27. Liu M., Huang W., Wu D., and Priestley J.V. TRPV1, but not P2X, requires cholesterol for its function and membrane expression in rat nociceptors. Eur J Neurosci 24 (2006) 1-6
28. Liu M., Liu M.C., Magoulas C., Priestley J.V., and Willmott N.J. Versatile regulation of cytosolic Ca2+ by vanilloid receptor I in rat dorsal root ganglion neurons. J Biol Chem 278 (2003) 5462-5472
29. Liu Y., Jiang N., Wu J., Dai W., and Rosenblum J.S. Polo-like kinases inhibited by wortmannin. Labeling site and downstream effects. J Biol Chem 282 (2007) 2505-2511
30. Maas Jr. J.W., Vogt S.K., Chan G.C., Pineda V.V., Storm D.R., and Muglia L.J. Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity. J Neurosci 25 (2005) 4118-4126
31. Martin T.F. PI(4, 5)P(2) regulation of surface membrane traffic. Curr Opin Cell Biol 13 (2001) 493-499
32. Morales J.A., Ram J.L., Song J., and Brown R.A. Acetaldehyde inhibits current through voltage-dependent calcium channels. Toxicol Appl Pharmacol 143 (1997) 70-74
33. Morenilla-Palao C., Planells-Cases R., Garcia-Sanz N., and Ferrer-Montiel A. Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. J Biol Chem 279 (2004) 25665-25672
34. Moriyama T., Higashi T., Togashi K., Iida T., Segi E., Sugimoto Y., et al. Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins. Mol Pain 1 (2005) 3
35. Morre D.J., and Morre D.M. Preparation of mammalian plasma membranes by aqueous two-phase partition. Biotechniques 7 (1989) 946-948 950-944, 956-948
36. Narita M., Miyoshi K., and Suzuki T. Functional reduction in mu-opioidergic system in the spinal cord under a neuropathic pain-like state following chronic ethanol consumption in the rat. Neuroscience 144 (2007) 777-782
37. Onishi Y., Honda M., Ogihara T., Sakoda H., Anai M., Fujishiro M., et al. Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation. Biochem Biophys Res Commun 303 (2003) 788-794
38. Pike L.J., and Casey L. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains. J Biol Chem 271 (1996) 26453-26456
39. Pike L.J., and Miller J.M. Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover. J Biol Chem 273 (1998) 22298-22304
40. Pomonis J.D., Harrison J.E., Mark L., Bristol D.R., Valenzano K.J., and Walker K. N-(4-tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II In vivo characterization in rat models of inflammatory and neuropathic pain. J Pharmacol Exp Ther 306 (2003) 387-393
41. Premkumar L.S., and Ahern G.P. Induction of vanilloid receptor channel activity by protein kinase C. Nature 408 (2000) 985-990
42. Prescott E., and Julius D. A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science 300 (2003) 1248
43. Rashid M.H., Inoue M., Toda K., and Ueda H. Loss of peripheral morphine analgesia contributes to the reduced effectiveness of systemic morphine in neuropathic pain. J Pharmacol Exp Ther 309 (2004) 380-387
44. Rathee P.K., Distler C., Obreja O., Neuhuber W., Wang G.K., Wang S.Y., et al. PKA/AKAP/VR-1 module: a common link of Gs-mediated signaling to thermal hyperalgesia. J Neurosci 22 (2002) 4740-4745
45. Ross R.A., Gibson T.M., Brockie H.C., Leslie M., Pashmi G., Craib S.J., et al. Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. Br J Pharmacol 132 (2001) 631-640
46. Schafer M., Imai Y., Uhl G.R., and Stein C. Inflammation enhances peripheral mu-opioid receptor-mediated analgesia, but not mu-opioid receptor transcription in dorsal root ganglia. Eur J Pharmacol 279 (1995) 165-169
47. Smith J.A., Davis C.L., and Burgess G.M. Prostaglandin E2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A. Eur J Neurosci 12 (2000) 3250-3258
48. Solem M., McMahon T., and Messing R.O. Protein kinase A regulates inhibition of N- and P/Q-type calcium channels by ethanol in PC12 cells. J Pharmacol Exp Ther 282 (1997) 1487-1495
49. Stein A.T., Ufret-Vincenty C.A., Hua L., Santana L.F., and Gordon S.E. Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol 128 (2006) 509-522
50. Suh B.C., and Hille B. Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron 35 (2002) 507-520
51. Takeuchi M., and Saito T. Cytotoxicity of acetaldehyde-derived advanced glycation end-products (AA-AGE) in alcoholic-induced neuronal degeneration. Alcohol Clin Exp Res 29 (2005) 220S-224S
52. Tomas M., Marin P., Megias L., Egea G., and Renau-Piqueras J. Ethanol perturbs the secretory pathway in astrocytes. Neurobiol Dis 20 (2005) 773-784
53. Trevisani M., Smart D., Gunthorpe M.J., Tognetto M., Barbieri M., Campi B., et al. Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nat Neurosci 5 (2002) 546-551
54. Tsukamoto S., Kanegae T., Isobe E., Hirose M., and Nagoya T. Determinations of free and bound ethanol, acetaldehyde, and acetate in human blood and urine by headspace gas chromatography. Nihon Arukoru Yakubutsu Igakkai Zasshi 33 (1998) 200-209
55. Van Buren J.J., Bhat S., Rotello R., Pauza M.E., and Premkumar L.S. Sensitization and translocation of TRPV1 by insulin and IGF-I. Mol Pain 1 (2005) 17
56. Vellani V., Mapplebeck S., Moriondo A., Davis J.B., and McNaughton P.A. Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. J Physiol 534 (2001) 813-825
57. Vetter I., Wyse B.D., Monteith G.R., Roberts-Thomson S.J., and Cabot P.J. The mu opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway. Mol Pain 2 (2006) 22
58. Vittadini G., Buonocore M., Colli G., Terzi M., Fonte R., and Biscaldi G. Alcoholic polyneuropathy: a clinical and epidemiological study. Alcohol Alcohol 36 (2001) 393-400
59. Wetterling T., Veltrup C., Driessen M., and John U. Drinking pattern and alcohol-related medical disorders. Alcohol Alcohol 34 (1999) 330-336
60. Xu M., and Woodward J.J. Ethanol inhibition of NMDA receptors under conditions of altered protein kinase A activity. J Neurochem 96 (2006) 1760-1767
61. Yang Z.W., Wang J., Zheng T., Altura B.T., and Altura B.M. Importance of PKC and PI3Ks in ethanol-induced contraction of cerebral arterial smooth muscle. Am J Physiol Heart Circ Physiol 280 (2001) H2144-H2152
62. Yang Z.W., Wang J., Zheng T., Altura B.T., and Altura B.M. Roles of tyrosine kinase-, 1-phosphatidylinositol 3-kinase-, and mitogen-activated protein kinase-signaling pathways in ethanol-induced contractions of rat aortic smooth muscle: possible relation to alcohol-induced hypertension. Alcohol 28 (2002) 17-28
63. Zeng F., McHugh D., and Beech D. Inhibition of human TRPC5 activity by PIP2. Faseb J 20 (2006) A329-A330
64. Zhang F.X., Rubin R., and Rooney T.A. Ethanol induces apoptosis in cerebellar granule neurons by inhibiting insulin-like growth factor 1 signaling. J Neurochem 71 (1998) 196-204
65. Zhang X., Huang J., and McNaughton P.A. NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. Embo J 24 (2005) 4211-4223
66. Zhou Y., Li G.D., and Zhao Z.Q. State-dependent phosphorylation of epsilon-isozyme of protein kinase C in adult rat dorsal root ganglia after inflammation and nerve injury. J Neurochem 85 (2003) 571-580
67. Zhu W., and Oxford G.S. Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1. Mol Cell Neurosci (2007) [Epub ahead of print]
68. Zhuang Z.Y., Xu H., Clapham D.E., and Ji R.R. Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. J Neurosci 24 (2004) 8300-8309
69. Zuba D., Piekoszewski W., Pach J., Winnik L., and Parczewski A. Concentration of ethanol and other volatile compounds in the blood of acutely poisoned alcoholics. Alcohol 26 (2002) 17-22