Structural basis of inward rectification: Cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 Å resolution

Cell

Volumn 111, Issue 7, 2002, Pages 957-965

  Nishida, Motohiko ^a   MacKinnon, Roderick ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; PROTEIN SUBUNIT;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

EID: 0037184996     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)01227-8     Document Type: Article

References (60)

1. + channel. J. Biol. Chem. 276:2001;12712-12717.
2. Baukrowitz T., Tucker S.J., Schulte U., Benndorf K., Ruppersberg J.P., Fakler B. Inward rectification in KATP channels. a pH switch in the pore EMBO J. 18:1999;847-853.
3. Breitwieser G.E., Szabo G. Uncoupling of cardiac muscarinic and beta-adrenergic receptors from ion channels by a guanine nucleotide analogue. Nature. 317:1985;538-540.
4. Brunger A.T., Adams P.D., Clore G.M., DeLano W.L., Gros P., Grosse-Kuntsleve R.W., Jiang J.S., Kuszewski J., Nilges M., Pannu N.S.et al. Crystallography & NMR system. a new software suite for macromolecular structure determination Acta Crystallogr. D Biol. Crystallogr. 54:1998;905-921.
5. Burgen A.S.V., Terroux K.G. On the negative inotropic effect in the cat's auricle. J. Physiol. 120:1953;449-464.
6. Chen J., DeVivo M., Dingus J., Harry A., Li J., Sui J., Carty D.J., Blank J.L., Exton J.H., Stoffel R.H. A region of adenylyl cyclase 2 critical for regulation by G protein beta gamma subunits. Science. 268:1995;1166-1169.
7. CCP4 Collaborative Computational Project 4) The CCP4 suite. programs for protein crystallography Acta Crystallogr. D. 50:1994;760-763.
8. Cowtan K. Dm. an automated procedure for phase improvement by density modification Joint CCP4 and ESF-EACBM Newsletter on Protein Crystallography. 31:1994;34-38.
9. + channel. expression cloning and molecular properties Proc. Natl. Acad. Sci. USA. 90:1993;10235-10239.
10. + conduction and selectivity Science. 280:1998;69-77.
11. + channels. Science. 266:1994;1068-1072.
12. Gaudet R., Bohm A., Sigler P.B. Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin. Cell. 87:1996;577-588.
13. + channel beta subunit. Cell. 97:1999;943-952.
14. + channels. Science. 289:2000;123-127.
15. Guo D., Lu Z. Mechanism of IRK1 channel block by intracellular polyamines. J. Gen. Physiol. 115:2000;799-814.
16. Hagiwara S., Miyazaki S., Rosenthal N.P. Potassium current and the effect of cesium on this current during anomalous rectification of the egg cell membrane of a starfish. J. Gen. Physiol. 67:1976;621-638.
17. + channel signature sequence. Biophys. J. 66:1994;1061-1067.
18. Hille B. Ion Channels of Excitable Membranes. 2001;Sinauer Associates, Inc, Sunderland, MA.
19. Hille B., Schwarz W. Potassium channels as multi-ion single-file pores. J. Gen. Physiol. 72:1978;409-442.
20. Ho K., Nichols C.G., Lederer W.J., Lytton J., Vassilev P.M., Kanazirska M.V., Hebert S.C. Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature. 362:1993;31-38.
21. Inagaki N., Gonoi T., Clement J.P., Namba N., Inazawa J., Gonzalez G., Aguilar-Bryan L., Seino S., Bryan J. Reconstitution of IKATP. an inward rectifier subunit plus the sulfonylurea receptor Science. 270:1995;1166-1170.
22. Jiang Y., Lee A., Chen J., Cadene M., Chait B.T., MacKinnon R. Crystal structure and mechanism of a calcium-gated potassium channel. Nature. 417:2002;515-522. a.
23. Jiang Y., Lee A., Chen J., Cadene M., Chait B.T., MacKinnon R. The open pore conformation of potassium channels. Nature. 417:2002;523-526. b.
24. Jin T., Peng L., Mirshahi T., Rohacs T., Chan K.W., Sanchez R., Logothetis D.E. The betagamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment. Mol. Cell. 10:2002;469-481.
25. Jones T.A., Zou J.Y., Cowan S.W., Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A. 47:1991;110-119.
26. Katz B. Les constants électriques de la membrane du muscle. Arch. Sci. Physiol. (Paris). 3:1949;285-299.
27. + channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins. Nature. 374:1995;135-141.
28. Kreusch A., Pfaffinger P.J., Stevens C.F., Choe S. Crystal structure of the tetramerization domain of the Shaker potassium channel. Nature. 392:1998;945-948.
29. + channel. J. Physiol. 531:2001;645-660.
30. Kubo Y., Baldwin T.J., Jan Y.N., Jan L.Y. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature. 362:1993;127-133. a.
31. Kubo Y., Reuveny E., Slesinger P.A., Jan Y.N., Jan L.Y. Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel. Nature. 364:1993;802-806. b.
32. + channels by adenosine in isolated atrial cells. involvement of GTP-binding proteins Pflugers Arch. 407:1986;264-274.
33. + channel in heart. Nature. 325:1987;321-326.
34. Lopatin A.N., Makhina E.N., Nichols C.G. Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification. Nature. 372:1994;366-369.
35. Lopatin A.N., Makhina E.N., Nichols C.G. The mechanism of inward rectification of potassium channels. "long-pore plugging" by cytoplasmic polyamines J. Gen. Physiol. 106:1995;923-955.
36. + channel. Nature. 371:1994;243-246.
37. Lu Z., Klem A.M., Ramu Y. Ion conduction pore is conserved among potassium channels. Nature. 413:2001;809-813.
38. 2+. Nature. 325:1987;156-159.
39. Nichols C.G., Lopatin A.N. Inward rectifier potassium channels. Annu. Rev. Physiol. 59:1997;171-191.
40. Otwinowski Z., Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276:1997;307-326.
41. Pearson W.L., Nichols C.G. Block of the Kir2.1 channel pore by alkylamine analogues of endogenous polyamines. J. Gen. Physiol. 112:1998;351-363.
42. Pfaffinger P.J., Martin J.M., Hunter D.D., Nathanson N.M., Hille B. GTP-binding proteins couple cardiac muscarinic receptors to a K channel. Nature. 317:1985;536-538.
43. Reuveny E., Slesinger P.A., Inglese J., Morales J.M., Iniguez-Lluhi J.A., Lefkowitz R.J., Bourne H.R., Jan Y.N., Jan L.Y. Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits. Nature. 370:1994;143-146.
44. + channels in isolated pacemaker cells of the mammalian heart. Nature. 303:1983;250-253.
45. + channel. J. Gen. Physiol. 112:1998;211-221.
46. 2+ of the inward rectifier, IRK1. J. Physiol. 478:1994;1-6.
47. + channels. Kir2.0 and Kir3.0 Rev. Physiol. Biochem. Pharmacol. 145:2002;47-179.
48. + channels. Science. 264:1994;844-847.
49. + channel IRK1. EMBO J. 14:1995;5532-5541.
50. Trautwein W., Dudel J. Zum mechanismus der membranwirkung des acetyl-cholin an der herzmuskelfaser. Pflugers Arch. 266:1958;324-334.
51. Vandenberg C.A. Inward rectification of a potassium channel in cardiac ventricular cells depends on internal magnesium ions. Proc. Natl. Acad. Sci. USA. 84:1987;2560-2564.
52. Weeks C.M., Miller R. The design and implementation of SnB version 2.0. J. Appl. Crystallogr. 32:1999;120-124.
53. Weiss M.S., Wacker T., Weckesser J., Welte W., Schulz G.E. The three-dimensional structure of porin from Rhodobacter capsulatus at 3 Å resolution. FEBS Lett. 267:1990;268-272.
54. + channels localized to a single negatively charged residue. Nature. 371:1994;246-249.
55. Wickman K., Clapham D.E. Ion channel regulation by G proteins. Physiol. Rev. 75:1995;865-885.
56. Woodhull A.M. Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61:1973;687-708.
57. + channel. Neuron. 14:1995;1047-1054. a.
58. Yang J., Jan Y.N., Jan L.Y. Determination of the subunit stoichiometry of an inwardly rectifying potassium channel. Neuron. 15:1995;1441-1447. b.
59. Yifrach O., MacKinnon R. Energetics of pore opening in a voltage-gated k(+) channel. Cell. 111:2002;231-239.
60. + channel-Fab complex at 2.0 Å resolution. Nature. 414:2001;43-48.