Disruption of an intersubunit electrostatic bond is a critical step in glycine receptor activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 17, 2010, Pages 7987-7992

  Todorovic, Jelena ^a   Welsh, Brian T ^a   Bertaccini, Edward J ^b   Trudell, James R ^b   Mihic, S John ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cysteine substitution; Electrophysiology; Mutagenesis; Xenopus oocytes

Indexed keywords

ARGININE; CYSTEINE; GLYCINE RECEPTOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DISULFIDE BOND; ELECTROPHYSIOLOGY; MOLECULAR INTERACTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; ASPARTIC ACID; BASE SEQUENCE; DNA, COMPLEMENTARY; ELECTROPHYSIOLOGY; ION CHANNEL GATING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PATCH-CLAMP TECHNIQUES; RECEPTORS, GLYCINE; SEQUENCE ANALYSIS, DNA; STATIC ELECTRICITY; SYNAPTIC TRANSMISSION; XENOPUS;

EID: 77952377218     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1001845107     Document Type: Article

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