Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position α267

Journal of Biological Chemistry

Volumn 273, Issue 6, 1998, Pages 3314-3319

  Ye, Qing ^a   Koltchine, Vladimir V ^a   Mihic, S John ^b,c   Mascia, Maria Paola ^b   Wick, Marilee J ^b   Finn, Suzanne E ^a   Harrison, Neil L ^a   Harris, R Adron ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE RECEPTOR;

ALCOHOL INTOXICATION; ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; BRAIN LEVEL; CENTRAL NERVOUS SYSTEM DEPRESSION; CHANNEL GATING; CORRELATION FUNCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANIMALS; CELL LINE; ETHANOL; HUMANS; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, GABA; RECEPTORS, GLYCINE; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SERINE; XENOPUS;

EID: 0032488831     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.6.3314     Document Type: Article

References (35)

1. Deitrich, R. A., Dunwiddie, T. V., Harris, R. A., and Erwin, V. G. (1989) Pharmacol. Rev. 41, 491-537
2. Samson, H. H., and Harris, R. A. (1992) Trends Pharmacol. Sci. 13, 206
3. Lovinger, D. M., White, G., and Weight, F. F. (1989) Science 243, 1721-1724
4. Dildy-Mayfield, J. E., and Harris, R. A. (1995) J. Neurosci. 15, 3162-3171
5. Lovinger, D. M. (1993) Neurosci. Lett. 159, 83-87
6. Mihic, S. J., and Harris, R. A. (1996) in Pharmacological Effects of Ethanol on the Nervous System (Deitrich, R. A., and Erwin, V. G., eds) pp. 51-72, CRC Press, Boca Raton, FL
7. Betz, H. (1991) Trends Neurosci. 14, 458-461
8. Williams, K. L., Ferko, A. P., Barbieri, E. J., and DiGregorio, G. J. (1995) Pharmacol. Biochem. Behav. 50, 199-205
9. Celentano, J. J., Gibbs, T. T., and Farb, D. H. (1988) Brain Res. 455, 377-380
10. Aguayo, L. G., and Pancetti, F. C. (1994) J. Pharmacol. Exp. Ther. 270, 61-69
11. Engblom, A. C., and Åkerman, K. E. O. (1991) J. Neurochem. 57, 384-390
12. Mascia, M. P., Mihic, S. J., Schofield, P., and Harris, R. A. (1996) Mol. Pharmacol. 50, 402-406
13. Mascia, M. P., Machu, T. K., and Harris, R. A. (1996) Br. J. Pharmacol. 119, 1331-1336
14. Betz, H. (1990) Neuron 5, 383-392
15. Ortells, M. O., and Lunt, G. G. (1995) Trends Neurosci. 18, 121-127
16. Vandenberg, R. J., and Schofield, P. R. (1994) Handbook of Membrane Channels, pp. 317-332, Academic Press, Orlando, FL
17. Mihic, S. J., Ye, Q., Wick, M., Koltchine, V. V., Finn, S. E., Krasowski, M. D., Mascia, M. P., Valenzuela, C. F., Hanson, K. K., Greenblatt, E. P., Harris, R. A., and Harrison, N. L. (1997) Nature 389, 385-389
18. Deng, W. P., and Nickoloff, J. A. (1992) Anal. Biochem. 200, 81
19. Mihic, S. J., Whiting, P. J., and Harris, R. A. (1994) Eur J. Pharmacol. 268, 209-214
20. Deleted in proof
21. Koltchine, V. V., Ye, Q., Finn, S. E., and Harrison, N. L. (1996) Neuropharmacology 35, 1445-1456
22. Mihic, S. J., and Harris, R. A. (1996) J. Pharmacol. Exp. Ther. 277, 411-416
23. Mihic, S. J., and Harris, R. A. (1996) BioTechniques 20, 802-804
24. Zamytanin, A. A. (1972) Prog. Biophys. Mol. Biol. 24, 107-123
25. Xu, M., and Akabas, M. H. (1996) J. Gen. Physiol. 107, 195-205
26. Leff, P. (1995) Trends Physiol. Sci. 16, 89-97
27. Strichartz, G. R. (1973) J. Gen. Physiol. 62, 37-57
28. Courtney, K. R. (1975) J. Pharmacol. Exp. Ther. 195, 225-236
29. Gready, J. E., Ranganathan, S., Schofield, P. R., Matsuo, Y., and Nishikawa, K. (1997) Protein Sci. 6, 983-998
30. Li, C., Peoples, R. W., and Weight, F. F. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8200-8204
31. Curry, S., Moss, G. W. J., Dickinson, R., Lieb, W. R., and Franks, N. P. (1991) Br. J. Pharmacol. 102, 167-173
32. Kyte, J., and Doolittle, R. F. (1982) J. Mol. Biol. 157, 105-132
33. Hopp, T. P., and Woods, K. R. (1981) Proc. Natl. Acad. Sci. U. S. A. 78, 3824-3828
34. Zimmerman, J. M., Eliezer, N., and Simha, R. (1968) J. Theor. Biol. 21, 170-201
35. McClave, J. T., and Dietrich, F. H. (1979) Statistics, pp. 492-508, Dellen Publishing, San Francisco, CA