PKCε has an alcohol-binding site in its second cysteine-rich regulatory domain

Biochemical Journal

Volumn 421, Issue 3, 2009, Pages 405-413

  Das, Joydip ^a   Pany, Satyabrata ^a   Rahman, Ghazi M ^a   Slater, Simon J ^b,c  

^a UNIVERSITY OF HOUSTON   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c Clinical Content and Editorial Services   (United States)

Author keywords

Alcohol binding site; Alcoholism; Fluorescence spectroscopy; Mass spectrometry (MS); Photoaffinity; Protein kinase C (PKC )

Indexed keywords

ALCOHOL CONSUMPTION; ALCOHOLISM; BINDING AFFINITIES; C1 DOMAIN; CONCENTRATION-DEPENDENT; KNOCKOUT MICE; LIGAND CONCENTRATION; PHORBOL ESTERS; PHOTOAFFINITY; PROTEIN KINASE; PROTEIN KINASE C; REGULATORY DOMAIN; SUB-DOMAINS; SUBDOMAIN; WILD TYPES;

BINDING ENERGY; CERIUM; CERIUM COMPOUNDS; ELECTRIC CONDUCTIVITY MEASUREMENT; ESTERS; ETHANOL; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; MASS SPECTROMETERS; MASS SPECTROMETRY;

BINDING SITES;

ALANINE; ALCOHOL; BUTANOL; HISTIDINE; OCTANOL; PHORBOL ESTER; PROTEIN KINASE C EPSILON; TYROSINE; ALCOHOL DERIVATIVE; RECOMBINANT PROTEIN;

ALCOHOL CONSUMPTION; ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; ENZYME ACTIVITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; ALCOHOLISM; CHEMISTRY; CONFORMATION; CRYSTALLIZATION; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

ALCOHOLISM; ALCOHOLS; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLIZATION; HUMANS; KINETICS; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN KINASE C-EPSILON; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 69249224549     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20082271     Document Type: Article

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