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Volumn 1406, Issue , 2011, Pages 84-105

Neurogenesis in Huntington's disease: Can studying adult neurogenesis lead to the development of new therapeutic strategies?

Author keywords

Adult neurogenesis; Cognitive deficit; Dentate gyrus; Genetic model; Hippocampus; Huntington's disease; Sub ventricular zone; Treatment

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPAKINE; ASIALOERYTHROPOIETIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CENTRAL STIMULANT AGENT; CYTOKINE; FIBROBLAST GROWTH FACTOR 2; FLUOXETINE; IMIPRAMINE; NEUROPEPTIDE Y; NEUROTROPHIC FACTOR; NOGGIN; PAROXETINE; SERTRALINE; UNCLASSIFIED DRUG;

EID: 79960835887     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.06.040     Document Type: Review
Times cited : (54)

References (211)
  • 1
    • 0034656167 scopus 로고    scopus 로고
    • Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus
    • M.A. Aberg, N.D. Aberg, H. Hedbäcker, J. Oscarsson, and P.S. Eriksson Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus J. Neurosci. 20 2000 2896 2903 (Pubitemid 30220315)
    • (2000) Journal of Neuroscience , vol.20 , Issue.8 , pp. 2896-2903
    • Aberg, M.A.I.1    Aberg, N.D.2    Hedbacker, H.3    Oscarsson, J.4    Eriksson, P.S.5
  • 2
    • 0013784893 scopus 로고
    • Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
    • J. Altman, and G.D. Das Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats J. Comp. Neurol. 124 1965 319 335
    • (1965) J. Comp. Neurol. , vol.124 , pp. 319-335
    • Altman, J.1    Das, G.D.2
  • 3
    • 33748971888 scopus 로고    scopus 로고
    • Strenuous, intensive, long-term exercise does not prevent or delay the onset of Huntington's disease
    • DOI 10.1016/j.mehy.2006.04.068, PII S0306987706003938
    • E.L. Altschuler Strenuous, intensive, long-term exercise does not prevent or delay the onset of Huntington's disease Med. Hypotheses 67 2006 1429 1430 (Pubitemid 44442641)
    • (2006) Medical Hypotheses , vol.67 , Issue.6 , pp. 1429-1430
    • Altschuler, E.L.1
  • 4
    • 0029392854 scopus 로고
    • HEAT repeats in the Huntington's disease protein
    • M.A. Andrade, and P. Bork HEAT repeats in the Huntington's disease protein Nat. Genet. 11 1995 115 116
    • (1995) Nat. Genet. , vol.11 , pp. 115-116
    • Andrade, M.A.1    Bork, P.2
  • 5
    • 7244236320 scopus 로고    scopus 로고
    • Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
    • DOI 10.1038/nature02998
    • M. Arrasate, S. Mitra, E.S. Schweitzer, M.R. Segal, and S. Finkbeiner Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death Nature 431 2004 805 810 (Pubitemid 39434070)
    • (2004) Nature , vol.431 , Issue.7010 , pp. 805-810
    • Arrasate, M.1    Mitra, S.2    Schweitzer, E.S.3    Segal, M.R.4    Finkbeiner, S.5
  • 6
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • DOI 10.1038/nm747
    • A. Arvidsson, T. Collin, D. Kirik, Z. Kokaia, and O. Lindvall Neuronal replacement from endogenous precursors in the adult brain after stroke Nat. Med. 8 2002 963 970 (Pubitemid 35033700)
    • (2002) Nature Medicine , vol.8 , Issue.9 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3    Kokaia, Z.4    Lindvall, O.5
  • 7
    • 33749841276 scopus 로고    scopus 로고
    • A progressive and cell non-autonomous increase in striatal neural stem cells in the Huntington's disease R6/2 mouse
    • DOI 10.1523/JNEUROSCI.2850-06.2006
    • C.M. Batista, T.E. Kippin, S. Willaime-Morawek, M.K. Shimabukuro, W. Akamatsu, and D. van der Kooy A progressive and cell non-autonomous increase in striatal neural stem cells in the Huntington's disease R6/2 mouse J. Neurosci. 26 2006 10452 10460 (Pubitemid 44564595)
    • (2006) Journal of Neuroscience , vol.26 , Issue.41 , pp. 10452-10460
    • Batista, C.M.C.1    Kippin, T.E.2    Willaime-Morawek, S.3    Shimabukuro, M.K.4    Akamatsu, W.5    Van Der Kooy, D.6
  • 8
    • 23244437460 scopus 로고    scopus 로고
    • Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation
    • DOI 10.1111/j.1471-4159.2005.03169.x
    • A. Bauer, K. Zilles, A. Matusch, C. Holzmann, O. Riess, and S. von Hörsten Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation J. Neurochem. 94 2005 639 650 (Pubitemid 41098496)
    • (2005) Journal of Neurochemistry , vol.94 , Issue.3 , pp. 639-650
    • Bauer, A.1    Zilles, K.2    Matusch, A.3    Holzmann, C.4    Riess, O.5    Von Horsten, S.6
  • 9
    • 34250171705 scopus 로고    scopus 로고
    • Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease
    • DOI 10.1016/j.neuroscience.2007.03.010, PII S0306452207003302
    • C.L. Benn, E.J. Slow, L.A. Farrell, R. Graham, Y. Deng, M.R. Hayden, and J.H. Cha Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease Neuroscience 147 2007 354 372 (Pubitemid 46907444)
    • (2007) Neuroscience , vol.147 , Issue.2 , pp. 354-372
    • Benn, C.L.1    Slow, E.J.2    Farrell, L.A.3    Graham, R.4    Deng, Y.5    Hayden, M.R.6    Cha, J.-H.J.7
  • 10
    • 0035448951 scopus 로고    scopus 로고
    • Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain
    • A. Benraiss, E. Chmielnicki, K. Lerner, D. Roh, and S.A. Goldman Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain J. Neurosci. 21 2001 6718 6731 (Pubitemid 32781116)
    • (2001) Journal of Neuroscience , vol.21 , Issue.17 , pp. 6718-6731
    • Benraiss, A.1    Chmielnicki, E.2    Lerner, K.3    Roh, D.4    Goldman, S.A.5
  • 13
    • 0035194446 scopus 로고    scopus 로고
    • IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures
    • DOI 10.1023/A:1012706908779
    • K.B. Bjugstad, W.M. Zawada, S. Goodman, and C.R. Freed IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures J. Inherit. Metab. Dis. 24 2001 631 647 (Pubitemid 33130085)
    • (2001) Journal of Inherited Metabolic Disease , vol.24 , Issue.6 , pp. 631-647
    • Bjugstad, K.B.1    Zawada, W.M.2    Goodman, S.I.3    Freed, C.R.4
  • 16
    • 0347626155 scopus 로고    scopus 로고
    • Exploratory Activity and Fear Conditioning Abnormalities Develop Early in R6/2 Huntington's Disease Transgenic Mice
    • DOI 10.1037/0735-7044.117.6.1233
    • V.J. Bolivar, K. Manley, and A. Messer Exploratory activity and fear conditioning abnormalities develop early in R6/2 Huntington's disease transgenic mice Behav. Neurosci. 117 2003 1233 1242 (Pubitemid 37549425)
    • (2003) Behavioral Neuroscience , vol.117 , Issue.6 , pp. 1233-1242
    • Bolivar, V.J.1    Manley, K.2    Messer, A.3
  • 17
    • 1642418261 scopus 로고    scopus 로고
    • Early exploratory behavior abnormalities in R6/1 Huntington's disease transgenic mice
    • DOI 10.1016/j.brainres.2004.01.021, PII S0006899304001234
    • V.J. Bolivar, K. Manley, and A. Messer Early exploratory behavior abnormalities in R6/1 Huntington's disease transgenic mice Brain Res. 1005 2004 29 35 (Pubitemid 38388397)
    • (2004) Brain Research , vol.1005 , Issue.1-2 , pp. 29-35
    • Bolivar, V.J.1    Manley, K.2    Messer, A.3
  • 18
    • 0036939332 scopus 로고    scopus 로고
    • Estrogen-receptor-dependent regulation of neural stem cell proliferation and differentiation
    • DOI 10.1006/mcne.2002.1194
    • K. Brännvall, L. Korhonen, and D. Lindholm Estrogen-receptor- dependent regulation of neural stem cell proliferation and differentiation Mol. Cell. Neurosci. 21 2002 512 520 (Pubitemid 36062736)
    • (2002) Molecular and Cellular Neuroscience , vol.21 , Issue.3 , pp. 512-520
    • Brannvall, K.1    Korhonen, L.2    Lindholm, D.3
  • 19
    • 34250889839 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis, synaptic plasticity and memory: Facts and hypotheses
    • E. Bruel-Jungerman, C. Rampon, and S. Laroche Adult hippocampal neurogenesis, synaptic plasticity and memory: facts and hypotheses Rev. Neurosci. 18 2007 93 114
    • (2007) Rev. Neurosci. , vol.18 , pp. 93-114
    • Bruel-Jungerman, E.1    Rampon, C.2    Laroche, S.3
  • 21
    • 0033306418 scopus 로고    scopus 로고
    • Restoring production of hippocampal neurons in old age
    • DOI 10.1038/13197
    • H.A. Cameron, and R.D. McKay Restoring production of hippocampal neurons in old age Nat. Neurosci. 2 1999 894 897 (Pubitemid 30602603)
    • (1999) Nature Neuroscience , vol.2 , Issue.10 , pp. 894-897
    • Cameron, H.A.1    McKay, R.D.G.2
  • 22
    • 0035833068 scopus 로고    scopus 로고
    • Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus
    • DOI 10.1002/cne.1040
    • H.A. Cameron, and R.D. McKay Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus J. Comp. Neurol. 435 2001 406 417 (Pubitemid 32574293)
    • (2001) Journal of Comparative Neurology , vol.435 , Issue.4 , pp. 406-417
    • Cameron, H.A.1    Mckay, R.D.G.2
  • 23
    • 0027302887 scopus 로고
    • Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat
    • DOI 10.1016/0306-4522(93)90335-D
    • H.A. Cameron, C.S. Woolley, B.S. McEwen, and E. Gould Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat Neuroscience 56 1993 337 344 (Pubitemid 23274753)
    • (1993) Neuroscience , vol.56 , Issue.2 , pp. 337-344
    • Cameron, H.A.1    Woolley, C.S.2    McEwen, B.S.3    Gould, E.4
  • 24
    • 4444350918 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease
    • DOI 10.1523/JNEUROSCI.1197-04.2004
    • J.M. Canals, J.R. Pineda, J.F. Torres-Peraza, M. Bosch, R. Martín-Ibañez, M.T. Muñoz, G. Mengod, P. Ernfors, and J. Alberch Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease J. Neurosci. 24 2004 7727 7739 (Pubitemid 39186828)
    • (2004) Journal of Neuroscience , vol.24 , Issue.35 , pp. 7727-7739
    • Canals, J.M.1    Pineda, J.R.2    Torres-Peraza, J.F.3    Bosch, M.4    Martin-Ibanez, R.5    Munoz, M.T.6    Mengod, G.7    Ernfors, P.8    Alberch, J.9
  • 27
    • 0033819849 scopus 로고    scopus 로고
    • Environmental stimulation increases survival in mice transgenic for exon 1 of the Huntington's disease gene
    • R.J. Carter, M.J. Hunt, and A.J. Morton Environmental stimulation increases survival in mice transgenic for exon 1 of the Huntington's disease gene Mov. Disord. 15 2000 925 937
    • (2000) Mov. Disord. , vol.15 , pp. 925-937
    • Carter, R.J.1    Hunt, M.J.2    Morton, A.J.3
  • 28
    • 79958024146 scopus 로고    scopus 로고
    • Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse Model of Huntington's Disease: Exercise, Adenosine Receptors and Ampakines
    • Cepeda, C.; Cummings, D.M.; Hickey, M.A.; Kleiman-Weiner, M.; Chen, J.Y.; Watson, J.B.; Levine, M.S.; 2010. Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse Model of Huntington's Disease: Exercise, Adenosine Receptors and Ampakines. PLoS Curr. 20, RRN1182.
    • (2010) PLoS Curr. , vol.20
    • Cepeda, C.1    Cummings D., .M.2    Hickey M., .A.3    Kleiman-Weiner, M.4    Chen J., .Y.5    Watson J., .B.6    Levine M., .S.7
  • 29
    • 0034283877 scopus 로고    scopus 로고
    • Transcriptional dysregulation in Huntington's disease
    • J.H. Cha Transcriptional dysregulation in Huntington's disease Trends Neurosci. 23 2000 387 392
    • (2000) Trends Neurosci. , vol.23 , pp. 387-392
    • Cha, J.H.1
  • 31
    • 0037248718 scopus 로고    scopus 로고
    • Fluoxetine-induced exacerbation of chorea in Huntington's disease? A case report
    • Germany
    • Chari S.; Quraishi S. H.; & Jainer A. K. (2003). Fluoxetine-induced exacerbation of chorea in Huntington's disease? A case report. Pharmacopsychiatry. Germany
    • (2003) Pharmacopsychiatry
    • Chari, S.1    Quraishi, S.H.2    Jainer, A.K.3
  • 32
    • 34948855498 scopus 로고    scopus 로고
    • Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease
    • DOI 10.1172/JCI31778
    • S.R. Cho, A. Benraiss, E. Chmielnicki, A. Samdani, A. Economides, and S.A. Goldman Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease J. Clin. Invest. 117 2007 2889 2902 (Pubitemid 47529619)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.10 , pp. 2889-2902
    • Cho, S.-R.1    Benraiss, A.2    Chmielnicki, E.3    Samdani, A.4    Economides, A.5    Goldman, S.A.6
  • 33
    • 33645107862 scopus 로고    scopus 로고
    • Neurogenesis in the adult hippocampus
    • Christie, and Cameron Neurogenesis in the adult hippocampus Hippocampus 16 2006 199 207
    • (2006) Hippocampus , vol.16 , pp. 199-207
    • Christie1    Cameron2
  • 34
    • 0035504331 scopus 로고    scopus 로고
    • Expression of the Huntington's disease transgene in neural stem cell cultures from R6/2 transgenic mice
    • DOI 10.1016/S0361-9230(01)00598-6, PII S0361923001005986
    • Q. Chu-LaGraff, X. Kang, and A. Messer Expression of the Huntington's disease transgene in neural stem cell cultures from R6/2 transgenic mice Brain Res. Bull. 56 2001 307 312 (Pubitemid 33069355)
    • (2001) Brain Research Bulletin , vol.56 , Issue.3-4 , pp. 307-312
    • Chu-LaGraff, Q.1    Kang, X.2    Messer, A.3
  • 37
    • 49549109150 scopus 로고    scopus 로고
    • Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: Restoration by the neuroprotective compound CEP-1347
    • P. Conforti, C. Ramos, B.L. Apostol, D.A. Simmons, H.P. Nguyen, O. Riess, L.M. Thompson, C. Zuccato, and E. Cattaneo Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: restoration by the neuroprotective compound CEP-1347 Mol. Cell. Neurosci. 39 2008 1 7
    • (2008) Mol. Cell. Neurosci. , vol.39 , pp. 1-7
    • Conforti, P.1    Ramos, C.2    Apostol, B.L.3    Simmons, D.A.4    Nguyen, H.P.5    Riess, O.6    Thompson, L.M.7    Zuccato, C.8    Cattaneo, E.9
  • 38
    • 0034002585 scopus 로고    scopus 로고
    • Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus
    • DOI 10.1002/(SICI)1098-1063(2000)10:2<169::AID-HIPO6>3.0.CO;2-W
    • L. Covolan, L.T. Ribeiro, B.M. Longo, and L.E. Mello Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus Hippocampus 10 2000 169 180 (Pubitemid 30216354)
    • (2000) Hippocampus , vol.10 , Issue.2 , pp. 169-180
    • Covolan, L.1    Ribeiro, L.T.C.2    Longo, B.M.3    Mello, L.E.A.M.4
  • 40
    • 79952223775 scopus 로고    scopus 로고
    • Huntington's disease: Can mice lead the way to treatment?
    • Z.R. Crook, and D. Housman Huntington's disease: can mice lead the way to treatment? Neuron 69 2011 423 435
    • (2011) Neuron , vol.69 , pp. 423-435
    • Crook, Z.R.1    Housman, D.2
  • 42
    • 17044375442 scopus 로고    scopus 로고
    • The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain
    • M.A. Curtis, E.B. Penney, J. Pearson, M. Dragunow, B. Connor, and R.L. Faull The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain Neuroscience 132 2005 777 788
    • (2005) Neuroscience , vol.132 , pp. 777-788
    • Curtis, M.A.1    Penney, E.B.2    Pearson, J.3    Dragunow, M.4    Connor, B.5    Faull, R.L.6
  • 43
    • 18544410106 scopus 로고    scopus 로고
    • Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
    • DOI 10.1016/S0092-8674(00)80513-9
    • S.W. Davies, M. Turmaine, B.A. Cozens, M. DiFiglia, A.H. Sharp, C.A. Ross, E. Scherzinger, E.E. Wanker, L. Mangiarini, and G.P. Bates Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation Cell 90 1997 537 548 (Pubitemid 27347243)
    • (1997) Cell , vol.90 , Issue.3 , pp. 537-548
    • Davies, S.W.1    Turmaine, M.2    Cozens, B.A.3    DiFiglia, M.4    Sharp, A.H.5    Ross, C.A.6    Scherzinger, E.7    Wanker, E.E.8    Mangiarini, L.9    Bates, G.P.10
  • 44
    • 79951866710 scopus 로고    scopus 로고
    • Exogenous neuropeptide y promotes in vivo hippocampal neurogenesis
    • 2010 Jan 21. [Electronic publication ahead of print]
    • M. Decressac, B. Wright, B. David, P. Tyers, M. Jaber, R.A. Barker, and A. Gaillard Exogenous neuropeptide Y promotes in vivo hippocampal neurogenesis Hippocampus 2010 2010 Jan 21. doi: 10.1002/hipo.20765. [Electronic publication ahead of print]
    • (2010) Hippocampus
    • Decressac, M.1    Wright, B.2    David, B.3    Tyers, P.4    Jaber, M.5    Barker, R.A.6    Gaillard, A.7
  • 45
    • 77957809832 scopus 로고    scopus 로고
    • Neuropeptide y modifies the disease course in the R6/2 transgenic model of Huntington's disease
    • M. Decressac, B. Wright, P. Tyers, A. Gaillard, and R.A. Barker Neuropeptide Y modifies the disease course in the R6/2 transgenic model of Huntington's disease Exp. Neurol. 226 2010 24 32
    • (2010) Exp. Neurol. , vol.226 , pp. 24-32
    • Decressac, M.1    Wright, B.2    Tyers, P.3    Gaillard, A.4    Barker, R.A.5
  • 46
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory?
    • W. Deng, J.B. Aimone, and F.H. Gage New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat. Rev. Neurosci. 11 2010 339 350
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 47
    • 0014753605 scopus 로고
    • Socio-psychiatric consequences of Huntington's disease
    • K. Dewhurst, J.E. Oliver, and A.L. McKnight Socio-psychiatric consequences of Huntington's disease Br. J. Psychiatry 116 1970 255 258
    • (1970) Br. J. Psychiatry , vol.116 , pp. 255-258
    • Dewhurst, K.1    Oliver, J.E.2    McKnight, A.L.3
  • 48
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • DOI 10.1126/science.277.5334.1990
    • M. DiFiglia, E. Sapp, K.O. Chase, S.W. Davies, G.P. Bates, J.P. Vonsattel, and N. Aronin Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain Science 277 1997 1990 1993 (Pubitemid 27449140)
    • (1997) Science , vol.277 , Issue.5334 , pp. 1990-1993
    • DiFiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6    Aronin, N.7
  • 49
    • 1642406567 scopus 로고    scopus 로고
    • Paroxetine Retards Disease Onset and Progression in Huntingtin Mutant Mice
    • DOI 10.1002/ana.20075
    • W. Duan, Z. Guo, H. Jiang, B. Ladenheim, X. Xu, J.L. Cadet, and M.P. Mattson Paroxetine retards disease onset and progression in Huntingtin mutant mice Ann. Neurol. 55 2004 590 594 (Pubitemid 38391979)
    • (2004) Annals of Neurology , vol.55 , Issue.4 , pp. 590-594
    • Duan, W.1    Guo, Z.2    Jiang, H.3    Ladenheim, B.4    Xu, X.5    Cadet, J.L.6    Mattson, M.P.7
  • 51
    • 36549036813 scopus 로고    scopus 로고
    • Psychiatric Symptoms in Huntington's Disease before Diagnosis: The Predict-HD Study
    • DOI 10.1016/j.biopsych.2006.11.034, PII S0006322306015617
    • K. Duff, J.S. Paulsen, L.J. Beglinger, D.R. Langbehn, J.C. Stout Predict-HD Investigators of the Huntington Study Group Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study Biol. Psychiatry 62 2007 1341 1346 (Pubitemid 350180721)
    • (2007) Biological Psychiatry , vol.62 , Issue.12 , pp. 1341-1346
    • Duff, K.1    Paulsen, J.S.2    Beglinger, L.J.3    Langbehn, D.R.4    Stout, J.C.5
  • 53
    • 33846462480 scopus 로고    scopus 로고
    • Stem cell transplantation for Huntington's disease
    • DOI 10.1016/j.expneurol.2006.11.007, PII S0014488606006157
    • S.B. Dunnett, and A.E. Rosser Stem cell transplantation for Huntington's disease Exp. Neurol. 203 2007 279 292 (Pubitemid 46149598)
    • (2007) Experimental Neurology , vol.203 , Issue.2 , pp. 279-292
    • Dunnett, S.B.1    Rosser, A.E.2
  • 56
    • 78650677351 scopus 로고    scopus 로고
    • Neurogenesis in R6/2 mouse model of Huntington's disease is impaired at the level of NeuroD1
    • V. Fedele, L. Roybon, U. Nordström, J.Y. Li, and P. Brundin Neurogenesis in R6/2 mouse model of Huntington's disease is impaired at the level of NeuroD1 Neuroscience 173 2010 76 81
    • (2010) Neuroscience , vol.173 , pp. 76-81
    • Fedele, V.1    Roybon, L.2    Nordström, U.3    Li, J.Y.4    Brundin, P.5
  • 57
    • 0034595722 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in Huntington disease
    • DOI 10.1016/S0006-8993(00)02237-X, PII S000689930002237X
    • I. Ferrer, E. Goutan, C. Marín, M.J. Rey, and T. Ribalta Brain-derived neurotrophic factor in Huntington disease Brain Res. 866 2000 257 261 (Pubitemid 30313028)
    • (2000) Brain Research , vol.866 , Issue.1-2 , pp. 257-261
    • Ferrer, I.1    Goutan, E.2    Marin, C.3    Rey, M.J.4    Ribalta, T.5
  • 58
    • 0020768840 scopus 로고
    • Psychiatric features of Huntington's disease: Recent approaches and findings
    • S.E. Folstein, and M.F. Folstein Psychiatric features of Huntington's disease: recent approaches and findings Psychiatr. Dev. 1 1983 193 205
    • (1983) Psychiatr. Dev. , vol.1 , pp. 193-205
    • Folstein, S.E.1    Folstein, M.F.2
  • 59
    • 0020954957 scopus 로고
    • The association of affective disorder with Huntington's Disease in a case series and in families
    • S. Folstein, M.H. Abbott, G.A. Chase, B.A. Jensen, and M.F. Folstein The association of affective disorder with Huntington's disease in a case series and in families Psychol. Med. 13 1983 537 542 (Pubitemid 13019019)
    • (1983) Psychological Medicine , vol.13 , Issue.3 , pp. 537-542
    • Folstein, S.E.1    Abbott, M.H.2    Chase, G.A.3
  • 61
    • 26944493771 scopus 로고    scopus 로고
    • A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse
    • DOI 10.1111/j.1460-9568.2005.04349.x
    • H.E. Gibson, K. Reim, N. Brose, A.J. Morton, and S. Jones A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse Eur. J. Neurosci. 22 2005 1701 1712 (Pubitemid 41482958)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.7 , pp. 1701-1712
    • Gibson, H.E.1    Reim, K.2    Brose, N.3    Morton, A.J.4    Jones, S.5
  • 62
    • 45149107487 scopus 로고    scopus 로고
    • Mechanisms of neurodegeneration in Huntington's disease
    • DOI 10.1111/j.1460-9568.2008.06310.x
    • J.M. Gil, and A.C. Rego Mechanisms of neurodegeneration in Huntington's disease Eur. J. Neurosci. 27 2008 2803 2820 (Pubitemid 351832229)
    • (2008) European Journal of Neuroscience , vol.27 , Issue.11 , pp. 2803-2820
    • Gil, J.M.1    Rego, A.C.2
  • 63
    • 60549103857 scopus 로고    scopus 로고
    • The R6 lines of transgenic mice: A model for screening new therapies for Huntington's disease
    • J.M. Gil, and A.C. Rego The R6 lines of transgenic mice: a model for screening new therapies for Huntington's disease Brain Res. Rev. 59 2009 410 431
    • (2009) Brain Res. Rev. , vol.59 , pp. 410-431
    • Gil, J.M.1    Rego, A.C.2
  • 64
    • 2642545019 scopus 로고    scopus 로고
    • Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice
    • J.M. Gil, M. Leist, N. Popovic, P. Brundin, and A. Petersén Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice BMC Neurosci. 5 2004 17
    • (2004) BMC Neurosci. , vol.5 , pp. 17
    • Gil, J.M.1    Leist, M.2    Popovic, N.3    Brundin, P.4    Petersén, A.5
  • 65
  • 66
    • 84856287728 scopus 로고    scopus 로고
    • Screening of therapeutic strategies for Huntington's Disease in YAC128 transgenic mice
    • Feb 16. [Electronic publication ahead of print]
    • Gil-Mohapel, J.M.; 2001. Screening of therapeutic strategies for Huntington's Disease in YAC128 transgenic mice. CNS Neurosci. Ther. 2011 Feb 16. doi: 10.1111/j.1755-5949.2011.00246.x. [Electronic publication ahead of print].
    • (2001) CNS Neurosci. Ther.
    • Gil-Mohapel, J.M.1
  • 67
    • 78650615197 scopus 로고    scopus 로고
    • Modulation of adult neurogenesis by physical exercise and environmental enrichment: Insights for the treatment of neurological disorders
    • J. Kunlin, Transworld Research Network Kerala, India
    • J. Gil-Mohapel, J.M. Simpson, and B.R. Christie Modulation of adult neurogenesis by physical exercise and environmental enrichment: insights for the treatment of neurological disorders J. Kunlin, Nervous System Diseases Vol. 2010 Transworld Research Network Kerala, India 125 150
    • (2010) Nervous System Diseases Vol. , pp. 125-150
    • Gil-Mohapel, J.1    Simpson, J.M.2    Christie, B.R.3
  • 69
    • 0026597108 scopus 로고
    • Expression of adrenal steroid receptors by newly born cells and pyknotic cells in the dentate gyrus of the postnatal rat
    • E. Gould, D.C. Daniels, H.A. Cameron, and B.S. McEwen Expression of adrenal steroid receptors by newly born cells and pyknotic cells in the dentate gyrus of the postnatal rat Mol. Cell. Neurosci. 3 1992 44 48
    • (1992) Mol. Cell. Neurosci. , vol.3 , pp. 44-48
    • Gould, E.1    Daniels, D.C.2    Cameron, H.A.3    McEwen, B.S.4
  • 71
    • 0033363319 scopus 로고    scopus 로고
    • Learning enhances adult neurogenesis in the hippocampal formation
    • DOI 10.1038/6365
    • E. Gould, A. Beylin, P. Tanapat, A. Reeves, and T.J. Shors Learning enhances adult neurogenesis in the hippocampal formation Nat. Neurosci. 2 1999 260 265 (Pubitemid 30491297)
    • (1999) Nature Neuroscience , vol.2 , Issue.3 , pp. 260-265
    • Gould, E.1    Beylin, A.2    Tanapat, P.3    Reeves, A.4    Shors, T.J.5
  • 73
    • 0032550154 scopus 로고    scopus 로고
    • Kainic acid increases the proliferation of granule cell progenitors in the dentate gyrus of the adult rat
    • DOI 10.1016/S0006-8993(98)00030-4, PII S0006899398000304
    • W.P. Gray, and L.E. Sundstrom Kainic acid increases the proliferation of granule cell progenitors in the dentate gyrus of the adult rat Brain Res. 790 1998 52 59 (Pubitemid 28234487)
    • (1998) Brain Research , vol.790 , Issue.1-2 , pp. 52-59
    • Gray, W.P.1    Sundstrom, L.E.2
  • 78
    • 0014063233 scopus 로고
    • Huntington's chorea. Investigation into the prevalence of this disease in the area covered by the North East Metropolitan Regional Hospital Board
    • K.W. Heathfield Huntington's chorea. Investigation into the prevalence of this disease in the area covered by the North East Metropolitan Regional Hospital Board Brain 90 1967 203 232
    • (1967) Brain , vol.90 , pp. 203-232
    • Heathfield, K.W.1
  • 80
  • 81
    • 0344961865 scopus 로고    scopus 로고
    • The use of transgenic and knock-in mice to study Huntington's disease
    • DOI 10.1159/000072863
    • M.A. Hickey, and M.F. Chesselet The use of transgenic and knock-in mice to study Huntington's disease Cytogenet. Genome Res. 100 2003 276 286 (Pubitemid 37467815)
    • (2003) Cytogenetic and Genome Research , vol.100 , Issue.1-4 , pp. 276-286
    • Hickey, M.A.1    Chesselet, M.-F.2
  • 82
    • 0036074718 scopus 로고    scopus 로고
    • The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease
    • DOI 10.1046/j.1471-4159.2002.00804.x
    • M.A. Hickey, G.P. Reynolds, and A.J. Morton The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease J. Neurochem. 81 2002 46 59 (Pubitemid 34808853)
    • (2002) Journal of Neurochemistry , vol.81 , Issue.1 , pp. 46-59
    • Hickey, M.A.1    Reynolds, G.P.2    Morton, A.J.3
  • 85
    • 0036500862 scopus 로고    scopus 로고
    • Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with β-tubulin: Relevance to Huntington's disease
    • G. Hoffner, P. Kahlem, and P. Djian Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington's disease J. Cell Sci. 115 2002 941 948 (Pubitemid 34257379)
    • (2002) Journal of Cell Science , vol.115 , Issue.5 , pp. 941-948
    • Hoffner, G.1    Kahlem, P.2    Djian, P.3
  • 87
    • 0033009587 scopus 로고    scopus 로고
    • Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes
    • M.S. Hurlbert, W. Zhou, C. Wasmeier, F.G. Kaddis, J.C. Hutton, and C.R. Freed Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes Diabetes 48 1999 649 651 (Pubitemid 29106885)
    • (1999) Diabetes , vol.48 , Issue.3 , pp. 649-651
    • Hurlbert, M.S.1    Zhou, W.2    Wasmeier, C.3    Kaddis, F.G.4    Hutton, J.C.5    Freed, C.R.6
  • 88
    • 0033914470 scopus 로고    scopus 로고
    • Early alterations in gene expression and cell morphology in a mouse model of Huntington's disease
    • DOI 10.1046/j.1471-4159.2000.0750830.x
    • C. Iannicola, S. Moreno, S. Oliverio, R. Nardacci, A. Ciofi-Luzzatto, and M. Piacentini Early alterations in gene expression and cell morphology in a mouse model of Huntington's disease J. Neurochem. 75 2000 830 839 (Pubitemid 30485467)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.2 , pp. 830-839
    • Iannicola, C.1    Moreno, S.2    Oliverio, S.3    Nardacci, R.4    Ciofi-Luzzatto, A.5    Piacentini, M.6
  • 90
    • 0027384679 scopus 로고
    • A study of psychiatric morbidity in patients with Huntington's disease, their relatives, and controls. Admissions to psychiatric hospitals in Denmark from 1969 to 1991
    • P. Jensen, S.A. Sørensen, K. Fenger, and T.G. Bolwig A study of psychiatric morbidity in patients with Huntington's disease, their relatives, and controls. Admissions to psychiatric hospitals in Denmark from 1969 to 1991 Br. J. Psychiatry 163 1993 790 797 (Pubitemid 23352974)
    • (1993) British Journal of Psychiatry , vol.163 , Issue.DEC. , pp. 790-797
    • Jensen, P.1    Sorensen, S.A.2    Fenger, K.3    Bolwig, T.G.4
  • 91
    • 0037373179 scopus 로고    scopus 로고
    • Cerebral neurogenesis is induced by intranasal administration of growth factors
    • DOI 10.1002/ana.10506
    • K. Jin, L. Xie, J. Childs, Y. Sun, X.O. Mao, A. Logvinova, and D.A. Greenberg Cerebral neurogenesis is induced by intranasal administration of growth factors Ann. Neurol. 53 2003 405 409 (Pubitemid 36258647)
    • (2003) Annals of Neurology , vol.53 , Issue.3 , pp. 405-409
    • Jin, K.1    Xie, L.2    Childs, J.3    Sun, Y.4    Mao, X.O.5    Logvinova, A.6    Greenberg, D.A.7
  • 95
    • 0017701702 scopus 로고
    • Neurogenesis in the adult rat: Electron microscopic analysis of light radioautographs
    • M.S. Kaplan, and J.W. Hinds Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs Science 197 1977 1092 1094 (Pubitemid 8170019)
    • (1977) Science , vol.197 , Issue.4308 , pp. 1092-1094
    • Kaplan, M.S.1    Hinds, J.W.2
  • 96
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • DOI 10.1038/386493a0
    • G. Kempermann, H.G. Kuhn, and F.H. Gage More hippocampal neurons in adult mice living in an enriched environment Nature 386 1997 493 495 (Pubitemid 27164074)
    • (1997) Nature , vol.386 , Issue.6624 , pp. 493-495
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 97
    • 1842734672 scopus 로고    scopus 로고
    • Functional significance of adult neurogenesis
    • DOI 10.1016/j.conb.2004.03.001, PII S0959438804000339
    • G. Kempermann, L. Wiskott, and F.H. Gage Functional significance of adult neurogenesis Curr. Opin. Neurobiol. 14 2004 186 191 (Pubitemid 38479935)
    • (2004) Current Opinion in Neurobiology , vol.14 , Issue.2 , pp. 186-191
    • Kempermann, G.1    Wiskott, L.2    Gage, F.H.3
  • 98
    • 37549055802 scopus 로고    scopus 로고
    • Stem cell-based cell therapy for Huntington disease: A review
    • M. Kim, S.T. Lee, K. Chu, and S.U. Kim Stem cell-based cell therapy for Huntington disease: a review Neuropathology 28 2008 1 9
    • (2008) Neuropathology , vol.28 , pp. 1-9
    • Kim, M.1    Lee, S.T.2    Chu, K.3    Kim, S.U.4
  • 99
    • 20544452612 scopus 로고    scopus 로고
    • Dopamine specifically inhibits forebrain neural stem cell proliferation, suggesting a novel effect of antipsychotic drugs
    • DOI 10.1523/JNEUROSCI.1120-05.2005
    • T.E. Kippin, S. Kapur, and D. van der Kooy Dopamine specifically inhibits forebrain neural stem cell proliferation, suggesting a novel effect of antipsychotic drugs J. Neurosci. 25 2005 5815 5823 (Pubitemid 40847894)
    • (2005) Journal of Neuroscience , vol.25 , Issue.24 , pp. 5815-5823
    • Kippin, T.E.1    Kapur, S.2    Van Der Kooy, D.3
  • 100
    • 0035115942 scopus 로고    scopus 로고
    • Progression of symptoms in the early and middle stages of Huntington disease
    • S.C. Kirkwood, J.L. Su, P. Conneally, and T. Foroud Progression of symptoms in the early and middle stages of Huntington disease Arch. Neurol. 58 2001 273 278 (Pubitemid 32163165)
    • (2001) Archives of Neurology , vol.58 , Issue.2 , pp. 273-278
    • Kirkwood, S.C.1    Su, J.L.2    Conneally, P.M.3    Foroud, T.4
  • 101
    • 0034749125 scopus 로고    scopus 로고
    • The role of neural cell adhesion molecules in plasticity and repair
    • DOI 10.1016/S0165-0173(01)00093-5, PII S0165017301000935
    • J.Z. Kiss, E. Troncoso, Z. Djebbara, L. Vutskits, and D. Muller The role of neural cell adhesion molecules in plasticity and repair Brain Res. Brain Res. Rev. 36 2001 175 184 (Pubitemid 33020747)
    • (2001) Brain Research Reviews , vol.36 , Issue.2-3 , pp. 175-184
    • Kiss, J.Z.1    Troncoso, E.2    Djebbara, Z.3    Vutskits, L.4    Muller, D.5
  • 102
  • 104
    • 34249986143 scopus 로고    scopus 로고
    • Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington's disease
    • DOI 10.1016/j.brainres.2007.04.039, PII S0006899307008591
    • Z. Kohl, M. Kandasamy, B. Winner, R. Aigner, C. Gross, S. Couillard-Despres, U. Bogdahn, L. Aigner, and J. Winkler Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington's disease Brain Res. 1155 2007 24 33 (Pubitemid 46891433)
    • (2007) Brain Research , vol.1155 , Issue.1 , pp. 24-33
    • Kohl, Z.1    Kandasamy, M.2    Winner, B.3    Aigner, R.4    Gross, C.5    Couillard-Despres, S.6    Bogdahn, U.7    Aigner, L.8    Winkler, J.9
  • 107
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation
    • H.G. Kuhn, H. Dickinson-Anson, and F.H. Gage Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation J. Neurosci. 16 1996 2027
    • (1996) J. Neurosci. , vol.16 , pp. 2027
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 111
    • 5044224807 scopus 로고    scopus 로고
    • Genetic mouse models of Huntington's and Parkinson's diseases: Illuminating but imperfect
    • DOI 10.1016/j.tins.2004.08.008, PII S0166223604002747
    • M.S. Levine, C. Cepeda, M.A. Hickey, S.M. Fleming, and M.F. Chesselet Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect Trends Neurosci. 27 2004 691 697 (Pubitemid 39335840)
    • (2004) Trends in Neurosciences , vol.27 , Issue.11 , pp. 691-697
    • Levine, M.S.1    Cepeda, C.2    Hickey, M.A.3    Fleming, S.M.4    Chesselet, M.-F.5
  • 112
    • 1242338856 scopus 로고    scopus 로고
    • Huntingtin-protein interactions and the pathogenesis of Huntington's disease
    • S.H. Li, and X.J. Li Huntingtin-protein interactions and the pathogenesis of Huntington's disease Trends Genet. 20 2004 146 154
    • (2004) Trends Genet. , vol.20 , pp. 146-154
    • Li, S.H.1    Li, X.J.2
  • 113
    • 0032811511 scopus 로고    scopus 로고
    • Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice
    • DOI 10.1093/hmg/8.7.1227
    • H. Li, S.H. Li, A.L. Cheng, L. Mangiarini, G.P. Bates, and X.J. Li Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice Hum. Mol. Genet. 8 1999 1227 1236 (Pubitemid 29328991)
    • (1999) Human Molecular Genetics , vol.8 , Issue.7 , pp. 1227-1236
    • Li, H.1    Li, S.-H.2    Cheng, A.L.3    Mangiarini, L.4    Bates, G.P.5    Li, X.-J.6
  • 114
    • 26844498655 scopus 로고    scopus 로고
    • The use of the R6 transgenic mouse models of Huntington' s disease in attempts to develop novel therapeutic strategies
    • DOI 10.1602/neurorx.2.3.447
    • J.Y. Li, N. Popovic, and P. Brundin The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies NeuroRx 2 2005 447 464 (Pubitemid 41444878)
    • (2005) NeuroRx , vol.2 , Issue.3 , pp. 447-464
    • Li, J.Y.1    Popovic, N.2    Brundin, P.3
  • 117
    • 33745601099 scopus 로고    scopus 로고
    • Stem cells for the treatment of neurological disorders
    • DOI 10.1038/nature04960, PII N04960
    • O. Lindvall, and Z. Kokaia Stem cells for the treatment of neurological disorders Nature 441 2006 1094 1096 (Pubitemid 43990722)
    • (2006) Nature , vol.441 , Issue.7097 , pp. 1094-1096
    • Lindvall, O.1    Kokaia, Z.2
  • 118
    • 0033500593 scopus 로고    scopus 로고
    • Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation
    • L.A. Lione, R.J. Carter, M.J. Hunt, G.P. Bates, A.J. Morton, and S.B. Dunnett Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation J. Neurosci. 19 1999 10428 10437 (Pubitemid 30228050)
    • (1999) Journal of Neuroscience , vol.19 , Issue.23 , pp. 10428-10437
    • Lione, L.A.1    Carter, R.J.2    Hunt, M.J.3    Bates, G.P.4    Morton, A.J.5    Dunnett, S.B.6
  • 120
    • 57149122292 scopus 로고    scopus 로고
    • Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells
    • M.T. Lorincz, and V.A. Zawistowski Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells Mol. Cell. Neurosci. 40 2009 1 13
    • (2009) Mol. Cell. Neurosci. , vol.40 , pp. 1-13
    • Lorincz, M.T.1    Zawistowski, V.A.2
  • 121
    • 0035969336 scopus 로고    scopus 로고
    • Evaluation of R6/2 HD transgenic mice for therapeutic studies in Huntington's disease: Behavioral testing and impact of diabetes mellitus
    • DOI 10.1016/S0166-4328(01)00261-3, PII S0166432801002613
    • H.G. Lüesse, J. Schiefer, A. Spruenken, C. Puls, F. Block, and C.M. Kosinski Evaluation of R6/2 HD transgenic mice for therapeutic studies in Huntington's disease: behavioral testing and impact of diabetes mellitus Behav. Brain Res. 126 2001 185 195 (Pubitemid 33009421)
    • (2001) Behavioural Brain Research , vol.126 , Issue.1-2 , pp. 185-195
    • Luesse, H.-G.1    Schiefer, J.2    Spruenken, A.3    Puls, C.4    Block, F.5    Kosinski, C.M.6
  • 123
    • 34247402598 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease
    • DOI 10.1523/JNEUROSCI.5113-06.2007
    • G. Lynch, E.A. Kramar, C.S. Rex, Y. Jia, D. Chappas, C.M. Gall, and D.A. Simmons Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease J. Neurosci. 27 2007 4424 4434 (Pubitemid 46640726)
    • (2007) Journal of Neuroscience , vol.27 , Issue.16 , pp. 4424-4434
    • Lynch, G.1    Kramar, E.A.2    Rex, C.S.3    Jia, Y.4    Chappas, D.5    Gall, C.M.6    Simmons, D.A.7
  • 125
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • J.E. Malberg, A.J. Eisch, E.J. Nestler, and R.S. Duman Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus J. Neurosci. 20 2000 9104 9110 (Pubitemid 32042912)
    • (2000) Journal of Neuroscience , vol.20 , Issue.24 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 126
    • 0035179732 scopus 로고    scopus 로고
    • Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro
    • DOI 10.1016/S0014-2999(00)00904-3, PII S0014299900009043
    • H. Manev, T. Uz, N.R. Smalheiser, and R. Manev Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro Eur. J. Pharmacol. 411 2001 67 70 (Pubitemid 32013113)
    • (2001) European Journal of Pharmacology , vol.411 , Issue.1-2 , pp. 67-70
    • Manev, H.1    Uz, T.2    Smalheiser, N.R.3    Manev, R.4
  • 129
    • 77953094107 scopus 로고    scopus 로고
    • Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice
    • M.W. Marlatt, P.J. Lucassen, and H. van Praag Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice Brain Res. 1341 2010 93 99
    • (2010) Brain Res. , vol.1341 , pp. 93-99
    • Marlatt, M.W.1    Lucassen, P.J.2    Van Praag, H.3
  • 130
    • 0037194221 scopus 로고    scopus 로고
    • Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice
    • DOI 10.1002/cne.10295
    • C.A. Meade, Y.P. Deng, F.R. Fusco, N. Del Mar, S. Hersch, D. Goldowitz, and A. Reiner Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice J. Comp. Neurol. 449 2002 241 269 (Pubitemid 34734283)
    • (2002) Journal of Comparative Neurology , vol.449 , Issue.3 , pp. 241-269
    • Meade, C.A.1    Deng, Y.-P.2    Fusco, F.R.3    Del Mar, N.4    Hersch, S.5    Goldowitz, D.6    Reiner, A.7
  • 131
    • 0036165417 scopus 로고    scopus 로고
    • Mouse models of Huntington's disease
    • DOI 10.1016/S0165-6147(00)01884-8, PII S0165614700018848
    • L.B. Menalled, and M.F. Chesselet Mouse models of Huntington's disease Trends Pharmacol. Sci. 23 2002 32 39 (Pubitemid 34135973)
    • (2002) Trends in Pharmacological Sciences , vol.23 , Issue.1 , pp. 32-39
    • Menalled, L.B.1    Chesselet, M.-F.2
  • 132
    • 0023682977 scopus 로고
    • Use of bromodeoxyuridine-immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system
    • M.W. Miller, and R.S. Nowakowski Use of bromodeoxyuridine- immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system Brain Res. 457 1988 44 52
    • (1988) Brain Res. , vol.457 , pp. 44-52
    • Miller, M.W.1    Nowakowski, R.S.2
  • 133
    • 33645106157 scopus 로고    scopus 로고
    • Stress and adult neurogenesis
    • C. Mirescu, and E. Gould Stress and adult neurogenesis Hippocampus 16 2006 233 238
    • (2006) Hippocampus , vol.16 , pp. 233-238
    • Mirescu, C.1    Gould, E.2
  • 134
    • 2942541217 scopus 로고    scopus 로고
    • Harnessing endogenous stem cells to treat neurodegenerative disorders of the basal ganglia
    • DOI 10.1016/j.parkreldis.2004.02.013, PII S1353802004000471, Striatal Plasticity in Health and Disease
    • P. Mohapel, and P. Brundin Harnessing endogenous stem cells to treat neurodegenerative disorders of the basal ganglia Parkinsonism Relat. Disord. 10 2004 259 264 (Pubitemid 38757805)
    • (2004) Parkinsonism and Related Disorders , vol.10 , Issue.5 , pp. 259-264
    • Mohapel, P.1    Brundin, P.2
  • 135
    • 62749197590 scopus 로고    scopus 로고
    • Lack of association between PSA-NCAM expression and migration in the rostral migratory stream of a Huntington's disease transgenic mouse model
    • L. Moraes, L.E. de Moraes Mello, M.K. Shimabukuro, C.M. de Castro Batista, and R. Mendez-Otero Lack of association between PSA-NCAM expression and migration in the rostral migratory stream of a Huntington's disease transgenic mouse model Neuropathology 29 2009 140 147
    • (2009) Neuropathology , vol.29 , pp. 140-147
    • Moraes, L.1    De Moraes Mello, L.E.2    Shimabukuro, M.K.3    De Castro Batista, C.M.4    Mendez-Otero, R.5
  • 136
    • 12144273983 scopus 로고    scopus 로고
    • Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease
    • DOI 10.1523/JNEUROSCI.3842-04.2005
    • A.J. Morton, N.I. Wood, M.H. Hastings, C. Hurelbrink, R.A. Barker, and E.S. Maywood Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease J. Neurosci. 25 2005 157 163 (Pubitemid 40110776)
    • (2005) Journal of Neuroscience , vol.25 , Issue.1 , pp. 157-163
    • Morton, A.J.1    Wood, N.I.2    Hastings, M.H.3    Hurelbrink, C.4    Barker, R.A.5    Maywood, E.S.6
  • 139
    • 0033782987 scopus 로고    scopus 로고
    • HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions
    • A.F. Neuwald, and T. Hirano HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions Genome Res. 10 2000 1445 1452
    • (2000) Genome Res. , vol.10 , pp. 1445-1452
    • Neuwald, A.F.1    Hirano, T.2
  • 140
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • M. Nibuya, S. Morinobu, and R.S. Duman Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments J. Neurosci. 15 1995 7539 7547
    • (1995) J. Neurosci. , vol.15 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 141
    • 67649249884 scopus 로고    scopus 로고
    • Modeling brain reserve: Experience-dependent neuronal plasticity in healthy and Huntington's disease transgenic mice
    • J. Nithianantharajah, C. Barkus, N. Vijiaratnam, O. Clement, and A.J. Hannan Modeling brain reserve: experience-dependent neuronal plasticity in healthy and Huntington's disease transgenic mice Am. J. Geriatr. Psychiatry 17 2009 196 209
    • (2009) Am. J. Geriatr. Psychiatry , vol.17 , pp. 196-209
    • Nithianantharajah, J.1    Barkus, C.2    Vijiaratnam, N.3    Clement, O.4    Hannan, A.J.5
  • 142
    • 33645103788 scopus 로고    scopus 로고
    • Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways
    • A.K. Olson, B.D. Eadie, C. Ernst, and B.R. Christie Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways Hippocampus 16 2006 250 260
    • (2006) Hippocampus , vol.16 , pp. 250-260
    • Olson, A.K.1    Eadie, B.D.2    Ernst, C.3    Christie, B.R.4
  • 143
    • 0028895098 scopus 로고
    • FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain
    • T.D. Palmer, J. Ray, and F.H. Gage FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain Mol. Cell. Neurosci. 6 1995 474 486
    • (1995) Mol. Cell. Neurosci. , vol.6 , pp. 474-486
    • Palmer, T.D.1    Ray, J.2    Gage, F.H.3
  • 144
    • 33745979171 scopus 로고    scopus 로고
    • Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in huntington's disease transgenic mice
    • DOI 10.1016/j.neuroscience.2006.04.013, PII S0306452206004933
    • T.Y. Pang, N.C. Stam, J. Nithianantharajah, M.L. Howard, and A.J. Hannan Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice Neuroscience 141 2006 569 584 (Pubitemid 44066652)
    • (2006) Neuroscience , vol.141 , Issue.2 , pp. 569-584
    • Pang, T.Y.C.1    Stam, N.C.2    Nithianantharajah, J.3    Howard, M.L.4    Hannan, A.J.5
  • 145
    • 58949085531 scopus 로고    scopus 로고
    • Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease
    • T.Y. Pang, X. Du, M.S. Zajac, M.L. Howard, and A.J. Hannan Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease Hum. Mol. Genet. 18 2009 753 766
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 753-766
    • Pang, T.Y.1    Du, X.2    Zajac, M.S.3    Howard, M.L.4    Hannan, A.J.5
  • 146
    • 0036895463 scopus 로고    scopus 로고
    • Rat forebrain neurogenesis and striatal neuron replacement after focal stroke
    • DOI 10.1002/ana.10393
    • J.M. Parent, Z.S. Vexler, C. Gong, N. Derugin, and D.M. Ferriero Rat forebrain neurogenesis and striatal neuron replacement after focal stroke Ann. Neurol. 52 2002 802 813 (Pubitemid 35403191)
    • (2002) Annals of Neurology , vol.52 , Issue.6 , pp. 802-813
    • Parent, J.M.1    Vexler, Z.S.2    Gong, C.3    Derugin, N.4    Ferriero, D.M.5
  • 147
    • 77549084218 scopus 로고    scopus 로고
    • Transient elevation of adult hippocampal neurogenesis after dopamine depletion
    • J.H. Park, and G. Enikolopov Transient elevation of adult hippocampal neurogenesis after dopamine depletion Exp. Neurol. 222 2010 267 276
    • (2010) Exp. Neurol. , vol.222 , pp. 267-276
    • Park, J.H.1    Enikolopov, G.2
  • 148
    • 0035449745 scopus 로고    scopus 로고
    • Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus
    • V. Pencea, K.D. Bingaman, S.J. Wiegand, and M.B. Luskin Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus J. Neurosci. 21 2001 6706 6717 (Pubitemid 32781115)
    • (2001) Journal of Neuroscience , vol.21 , Issue.17 , pp. 6706-6717
    • Pencea, V.1    Bingaman, K.D.2    Wiegand, S.J.3    Luskin, M.B.4
  • 149
    • 39249084415 scopus 로고    scopus 로고
    • The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model
    • Q. Peng, N. Masuda, M. Jiang, Q. Li, M. Zhao, C.A. Ross, and W. Duan The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model Exp. Neurol. 210 2008 154 163
    • (2008) Exp. Neurol. , vol.210 , pp. 154-163
    • Peng, Q.1    Masuda, N.2    Jiang, M.3    Li, Q.4    Zhao, M.5    Ross, C.A.6    Duan, W.7
  • 150
    • 0042318549 scopus 로고    scopus 로고
    • An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin-like growth factor-I in the dentate gyrus of adult female rat
    • DOI 10.1046/j.1460-9568.2003.02830.x
    • M. Perez-Martin, I. Azcoitia, J.L. Trejo, A. Sierra, and L.M. Garcia-Segura An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin-like growth factor-I in the dentate gyrus of adult female rat Eur. J. Neurosci. 18 2003 923 930 (Pubitemid 37059702)
    • (2003) European Journal of Neuroscience , vol.18 , Issue.4 , pp. 923-930
    • Perez-Martin, M.1    Azcoitia, I.2    Trejo, J.L.3    Sierra, A.4    Garcia-Segura, L.M.5
  • 151
    • 33747602312 scopus 로고    scopus 로고
    • Hypothalamic-endocrine aspects in Huntington's disease
    • DOI 10.1111/j.1460-9568.2006.04985.x
    • A. Petersén, and M. Björkqvist Hypothalamic-endocrine aspects in Huntington's disease Eur. J. Neurosci. 24 2006 961 967 (Pubitemid 44268127)
    • (2006) European Journal of Neuroscience , vol.24 , Issue.4 , pp. 961-967
    • Petersen, A.1    Bjorkqvist, M.2
  • 152
    • 0036983035 scopus 로고    scopus 로고
    • Huntington's disease: The mystery unfolds?
    • A. Petersén, and P. Brundin Huntington's disease: the mystery unfolds? Int. Rev. Neurobiol. 53 2002 315 339
    • (2002) Int. Rev. Neurobiol. , vol.53 , pp. 315-339
    • Petersén, A.1    Brundin, P.2
  • 154
    • 0036453663 scopus 로고    scopus 로고
    • Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice
    • DOI 10.1006/nbdi.2002.0534
    • A. Petersén, Z. Puschban, J. Lotharius, B. NicNiocaill, P. Wiekop, W.T. O'Connor, and P. Brundin Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice Neurobiol. Dis. 11 2002 134 146 (Pubitemid 35435681)
    • (2002) Neurobiology of Disease , vol.11 , Issue.1 , pp. 134-146
    • Petersen, A.1    Puschban, Z.2    Lotharius, J.3    NicNiocaill, B.4    Wiekop, P.5    O'Connor, W.T.6    Brundin, P.7
  • 156
    • 0026097561 scopus 로고
    • The clinical manifestation of mental disorder in Huntington's disease: A retrospective case record study of disease progression
    • S. Pflanz, J.A. Besson, K.P. Ebmeier, and S. Simpson The clinical manifestation of mental disorder in Huntington's disease: a retrospective case record study of disease progression Acta Psychiatr. Scand. 83 1991 53 60
    • (1991) Acta Psychiatr. Scand. , vol.83 , pp. 53-60
    • Pflanz, S.1    Besson, J.A.2    Ebmeier, K.P.3    Simpson, S.4
  • 157
    • 30744470119 scopus 로고    scopus 로고
    • Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment
    • DOI 10.1523/JNEUROSCI.3796-05.2005
    • W. Phillips, A.J. Morton, and R.A. Barker Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment J. Neurosci. 25 2005 11564 11576 (Pubitemid 43098449)
    • (2005) Journal of Neuroscience , vol.25 , Issue.50 , pp. 11564-11576
    • Phillips, W.1    Morton, A.J.2    Barker, R.A.3
  • 158
    • 33749019984 scopus 로고    scopus 로고
    • Limbic neurogenesis/plasticity in the R6/2 mouse model of Huntington's disease
    • DOI 10.1097/01.wnr.0000236855.85962.f6, PII 0000175620061023000013
    • W. Phillips, A. Jennifer Morton, and R.A. Barker Limbic neurogenesis/plasticity in the R6/2 mouse model of Huntington's disease Neuroreport 17 2006 1623 1627 (Pubitemid 44454769)
    • (2006) NeuroReport , vol.17 , Issue.15 , pp. 1623-1627
    • Phillips, W.1    Jennifer Morton, A.2    Barker, R.A.3
  • 159
    • 65249132310 scopus 로고    scopus 로고
    • Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin
    • M.A. Pouladi, R.K. Graham, J.M. Karasinska, Y. Xie, R.D. Santos, A. Petersén, and M.R. Hayden Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin Brain 132 2009 919 932
    • (2009) Brain , vol.132 , pp. 919-932
    • Pouladi, M.A.1    Graham, R.K.2    Karasinska, J.M.3    Xie, Y.4    Santos, R.D.5    Petersén, A.6    Hayden, M.R.7
  • 160
    • 36049044225 scopus 로고    scopus 로고
    • Animal models of Huntington's disease
    • S. Ramaswamy, J.L. McBride, and J.H. Kordower Animal models of Huntington's disease ILAR J. 48 2007 356 373 (Pubitemid 350194368)
    • (2007) ILAR Journal , vol.48 , Issue.4 , pp. 356-373
    • Ramaswamy, S.1    McBride, J.L.2    Kordower, J.H.3
  • 162
    • 0033066942 scopus 로고    scopus 로고
    • Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation
    • DOI 10.1046/j.1471-4159.1999.721773.x
    • G.P. Reynolds, C.F. Dalton, C.L. Tillery, L. Mangiarini, S.W. Davies, and G.P. Bates Brain neurotransmitter deficits in mice transgenic for the Huntington's disease mutation J. Neurochem. 72 1999 1773 1776 (Pubitemid 29140856)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.4 , pp. 1773-1776
    • Reynolds, G.P.1    Dalton, C.F.2    Tillery, C.L.3    Mangiarini, L.4    Davies, S.W.5    Bates, G.P.6
  • 164
    • 0032475931 scopus 로고    scopus 로고
    • Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
    • F. Saudou, S. Finkbeiner, D. Devys, and M.E. Greenberg Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions Cell 95 1998 55 66
    • (1998) Cell , vol.95 , pp. 55-66
    • Saudou, F.1    Finkbeiner, S.2    Devys, D.3    Greenberg, M.E.4
  • 170
    • 0034967122 scopus 로고    scopus 로고
    • Depression and Huntington's disease: Prevalence, clinical manifestations, etiology, and treatment
    • J.R. Slaughter, M.P. Martens, and K.A. Slaughter Depression and Huntington's disease: prevalence, clinical manifestations, etiology, and treatment CNS Spectr. 6 2001 306 326 (Pubitemid 32574137)
    • (2001) CNS Spectrums , vol.6 , Issue.4 , pp. 306-326
    • Slaughter, J.R.1    Martens, M.P.2    Slaughter, K.A.3
  • 173
    • 77949631994 scopus 로고    scopus 로고
    • Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease
    • B.R. Snyder, A.M. Chiu, D.J. Prockop, and A.W. Chan Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease PLoS One 5 2010 e9347
    • (2010) PLoS One , vol.5 , pp. 9347
    • Snyder, B.R.1    Chiu, A.M.2    Prockop, D.J.3    Chan, A.W.4
  • 174
    • 56249087909 scopus 로고    scopus 로고
    • Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease
    • J. Spampanato, X. Gu, X.W. Yang, and I. Mody Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease Neuroscience 157 2008 606 620
    • (2008) Neuroscience , vol.157 , pp. 606-620
    • Spampanato, J.1    Gu, X.2    Yang, X.W.3    Mody, I.4
  • 175
    • 0027276977 scopus 로고
    • Neuronal loss in the hippocampus in Huntington's disease: A comparison with HIV infection
    • E. Spargo, I.P. Everall, and P.L. Lantos Neuronal loss in the hippocampus in Huntington's disease: a comparison with HIV infection J. Neurol. Neurosurg. Psychiatry 56 1993 487 491 (Pubitemid 23171778)
    • (1993) Journal of Neurology Neurosurgery and Psychiatry , vol.56 , Issue.5 , pp. 487-491
    • Spargo, E.1    Everall, I.P.2    Lantos, P.L.3
  • 176
    • 2942620844 scopus 로고    scopus 로고
    • Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice
    • DOI 10.1111/j.0953-816X.2004.03374.x
    • T.L. Spires, H.E. Grote, S. Garry, P.M. Cordery, A. Van Dellen, C. Blakemore, and A.J. Hannan Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice Eur. J. Neurosci. 19 2004 2799 2807 (Pubitemid 38746396)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.10 , pp. 2799-2807
    • Spires, T.L.1    Grote, H.E.2    Garry, S.3    Cordery, P.M.4    Van Dellen, A.5    Blakemore, C.6    Hannan, A.J.7
  • 179
    • 35548937443 scopus 로고    scopus 로고
    • Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration
    • DOI 10.1523/JNEUROSCI.2461-07.2007
    • A.D. Strand, Z.C. Baquet, A.K. Aragaki, P. Holmans, L. Yang, C. Cleren, M.F. Beal, L. Jones, C. Kooperberg, J.M. Olson, and K.R. Jones Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration J. Neurosci. 27 2007 11758 11768 (Pubitemid 350006916)
    • (2007) Journal of Neuroscience , vol.27 , Issue.43 , pp. 11758-11768
    • Strand, A.D.1    Baquet, Z.C.2    Aragaki, A.K.3    Holmans, P.4    Yang, L.5    Cleren, C.6    Beal, M.F.7    Jones, L.8    Kooperberg, C.9    Olson, J.M.10    Jones, K.R.11
  • 181
    • 3242700600 scopus 로고    scopus 로고
    • Neurogenesis in the striatum of the quinolinic acid lesion model of Huntington's disease
    • DOI 10.1016/j.neuroscience.2004.04.061, PII S0306452204003483
    • A.S. Tattersfield, R.J. Croon, Y.W. Liu, A.P. Kells, R.L. Faull, and B. Connor Neurogenesis in the striatum of the quinolinic acid lesion model of Huntington's disease Neuroscience 127 2004 319 332 (Pubitemid 38950647)
    • (2004) Neuroscience , vol.127 , Issue.2 , pp. 319-332
    • Tattersfield, A.S.1    Croon, R.J.2    Liu, Y.W.3    Kells, A.P.4    Faull, R.L.M.5    Connor, B.6
  • 182
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group
    • The Huntington's Disease Collaborative Research Group
    • The Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group Cell 72 1993 971 983
    • (1993) Cell , vol.72 , pp. 971-983
  • 183
    • 0032189274 scopus 로고    scopus 로고
    • Changes in proliferating cell nuclear antigen, a protein involved in DNA repair, in vulnerable hippocampal neurons following global cerebral ischemia
    • DOI 10.1016/S0169-328X(98)00173-9, PII S0169328X98001739
    • G. Tomasevic, F. Kamme, and T. Wieloch Changes in proliferating cell nuclear antigen, a protein involved in DNA repair, in vulnerable hippocampal neurons following global cerebral ischemia Brain Res. Mol. Brain Res. 60 1998 168 176 (Pubitemid 28466582)
    • (1998) Molecular Brain Research , vol.60 , Issue.2 , pp. 168-176
    • Tomasevic, G.1    Kamme, F.2    Wieloch, T.3
  • 186
    • 0034643362 scopus 로고    scopus 로고
    • Delaying the onset of Huntington's in mice
    • DOI 10.1038/35008142
    • A. van Dellen, C. Blakemore, R. Deacon, D. York, and A.J. Hannan Delaying the onset of Huntington's in mice Nature 404 2000 721 722 (Pubitemid 30212388)
    • (2000) Nature , vol.404 , Issue.6779 , pp. 721-722
    • Van Dellen, A.1    Blakemore, C.2    Deacon, R.3    York, D.4    Hannan, A.J.5
  • 187
    • 42549092746 scopus 로고    scopus 로고
    • Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease
    • A. van Dellen, P.M. Cordery, T.L. Spires, C. Blakemore, and A.J. Hannan Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease BMC Neurosci. 9 2008 34
    • (2008) BMC Neurosci. , vol.9 , pp. 34
    • Van Dellen, A.1    Cordery, P.M.2    Spires, T.L.3    Blakemore, C.4    Hannan, A.J.5
  • 188
    • 33847270651 scopus 로고    scopus 로고
    • Reduced expression of PSA-NCAM in the hippocampus and piriform cortex of the R6/1 and R6/2 mouse models of Huntington's disease
    • DOI 10.1016/j.expneurol.2006.10.014, PII S0014488606005978
    • K. van der Borght, and P. Brundin Reduced expression of PSA-NCAM in the hippocampus and piriform cortex of the R6/1 and R6/2 mouse models of Huntington's disease Exp. Neurol. 204 2007 473 478 (Pubitemid 46330273)
    • (2007) Experimental Neurology , vol.204 , Issue.1 , pp. 473-478
    • Van Der Borght, K.1    Brundin, P.2
  • 191
    • 0033360314 scopus 로고    scopus 로고
    • Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
    • DOI 10.1038/6368
    • H. van Praag, G. Kempermann, and F.H. Gage Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus Nat. Neurosci. 2 1999 266 270 (Pubitemid 30491298)
    • (1999) Nature Neuroscience , vol.2 , Issue.3 , pp. 266-270
    • Van Praag, H.1    Kempermann, G.2    Gage, F.H.3
  • 192
    • 29644433445 scopus 로고    scopus 로고
    • Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease
    • DOI 10.1093/hmg/ddi407
    • J.M. Van Raamsdonk, Z. Murphy, E.J. Slow, B.R. Leavitt, and M.R. Hayden Selective degeneration of nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease Hum. Mol. Genet. 14 2005 3823 3835 (Pubitemid 43020084)
    • (2005) Human Molecular Genetics , vol.14 , Issue.24 , pp. 3823-3835
    • Van Raamsdonk, J.M.1    Murphy, Z.2    Slow, E.J.3    Leavitt, B.R.4    Hayden, M.R.5
  • 194
    • 17644368893 scopus 로고    scopus 로고
    • Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease
    • DOI 10.1523/JNEUROSCI.0590-05.2005
    • J.M. Van Raamsdonk, J. Pearson, E.J. Slow, S.M. Hossain, B.R. Leavitt, and M.R. Hayden Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease J. Neurosci. 25 2005 4169 4180 (Pubitemid 40563393)
    • (2005) Journal of Neuroscience , vol.25 , Issue.16 , pp. 4169-4180
    • Van Raamsdonk, J.M.1    Pearson, J.2    Slow, E.J.3    Hossain, S.M.4    Leavitt, B.R.5    Hayden, M.R.6
  • 199
    • 0033565402 scopus 로고    scopus 로고
    • Stimulation of neonatal and adult brain neurogenesis by subcutaneous injection of basic fibroblast growth factor
    • J.P. Wagner, I.B. Black, and E. DiCicco-Bloom Stimulation of neonatal and adult brain neurogenesis by subcutaneous injection of basic fibroblast growth factor J. Neurosci. 19 1999 6006 6016 (Pubitemid 29327934)
    • (1999) Journal of Neuroscience , vol.19 , Issue.14 , pp. 6006-6016
    • Wagner, J.P.1    Black, I.B.2    DiCicco-Bloom, E.3
  • 200
    • 0029895292 scopus 로고    scopus 로고
    • Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease
    • DOI 10.1002/ana.410400110
    • R.A. Weeks, P. Piccini, A.E. Harding, and D.J. Brooks Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease Ann. Neurol. 40 1996 49 54 (Pubitemid 26250142)
    • (1996) Annals of Neurology , vol.40 , Issue.1 , pp. 49-54
    • Weeks, R.A.1    Piccini, P.2    Harding, A.E.3    Brooks, D.J.4
  • 203
    • 77949317804 scopus 로고    scopus 로고
    • Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release
    • L.L. Wu, Y. Fan, S. Li, X.J. Li, and X.F. Zhou Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release J. Biol. Chem. 285 2010 5614 5623
    • (2010) J. Biol. Chem. , vol.285 , pp. 5614-5623
    • Wu, L.L.1    Fan, Y.2    Li, S.3    Li, X.J.4    Zhou, X.F.5
  • 204
    • 0142153442 scopus 로고    scopus 로고
    • Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology
    • DOI 10.1016/j.molbrainres.2003.08.009
    • G.J. Yohrling, G.C. Jiang, M.M. DeJohn, D.W. Miller, A.B. Young, K.E. Vrana, and J.H. Cha Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology Brain Res. Mol. Brain Res. 119 2003 28 36 (Pubitemid 37324795)
    • (2003) Molecular Brain Research , vol.119 , Issue.1 , pp. 28-36
    • Yohrling IV, G.J.1    Jiang, G.C.-T.2    DeJohn, M.M.3    Miller, D.W.4    Young, A.B.5    Vrana, K.E.6    Cha, J.-H.J.7
  • 205
    • 0037444445 scopus 로고    scopus 로고
    • Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease
    • Z.X. Yu, S.H. Li, J. Evans, A. Pillarisetti, H. Li, and X.J. Li Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease J. Neurosci. 23 2003 2193 2202 (Pubitemid 36368907)
    • (2003) Journal of Neuroscience , vol.23 , Issue.6 , pp. 2193-2202
    • Yu, Z.-X.1    Li, S.-H.2    Evans, J.3    Pillarisetti, A.4    Li, H.5    Li, X.-J.6
  • 206
    • 77951579326 scopus 로고    scopus 로고
    • Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice
    • M.S. Zajac, T.Y. Pang, N. Wong, B. Weinrich, L.S. Leang, J.M. Craig, R. Saffery, and A.J. Hannan Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice Hippocampus 20 2010 621 636
    • (2010) Hippocampus , vol.20 , pp. 621-636
    • Zajac, M.S.1    Pang, T.Y.2    Wong, N.3    Weinrich, B.4    Leang, L.S.5    Craig, J.M.6    Saffery, R.7    Hannan, A.J.8
  • 207
    • 0027380172 scopus 로고
    • Basic fibroblast growth factor enhances the growth of postnatal neostriatal GABAergic neurons in vitro
    • DOI 10.1006/exnr.1993.1118
    • D. Zhou, and M. DiFiglia Basic fibroblast growth factor enhances the growth of postnatal neostriatal GABAergic neurons in vitro Exp. Neurol. 122 1993 171 188 (Pubitemid 23290400)
    • (1993) Experimental Neurology , vol.122 , Issue.2 , pp. 171-188
    • Zhou, D.1    DiFiglia, M.2
  • 208
    • 0031856527 scopus 로고    scopus 로고
    • Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb
    • DOI 10.1006/mcne.1998.0684
    • T. Zigova, V. Pencea, S.J. Wiegand, and M.B. Luskin Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb Mol. Cell. Neurosci. 11 1998 234 245 (Pubitemid 28361411)
    • (1998) Molecular and Cellular Neurosciences , vol.11 , Issue.4 , pp. 234-245
    • Zigova, T.1    Pencea, V.2    Wiegand, S.J.3    Luskin, M.B.4
  • 209
    • 34047130812 scopus 로고    scopus 로고
    • Role of brain-derived neurotrophic factor in Huntington's disease
    • DOI 10.1016/j.pneurobio.2007.01.003, PII S0301008207000159
    • C. Zuccato, and E. Cattaneo Role of brain-derived neurotrophic factor in Huntington's disease Prog. Neurobiol. 81 2007 294 330 (Pubitemid 46528643)
    • (2007) Progress in Neurobiology , vol.81 , Issue.5-6 , pp. 294-330
    • Zuccato, C.1    Cattaneo, E.2
  • 211
    • 12744279625 scopus 로고    scopus 로고
    • Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: Neuronal selectivity and potential neuroprotective role of HAP1
    • B. Zucker, R. Luthi-Carter, J.A. Kama, A.W. Dunah, E.A. Stern, J.H. Fox, D.G. Standaert, A.B. Young, and S.J. Augood Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1 Hum. Mol. Genet. 14 2005 179 189
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 179-189
    • Zucker, B.1    Luthi-Carter, R.2    Kama, J.A.3    Dunah, A.W.4    Stern, E.A.5    Fox, J.H.6    Standaert, D.G.7    Young, A.B.8    Augood, S.J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.