Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity

Journal of Neurochemistry

Volumn 88, Issue 6, 2004, Pages 1352-1360

  Klivenyi, Peter ^a   Starkov, Anatoly A ^a   Calingasan, Noel Y ^a   Gardian, Gabrielle ^a   Browne, Susan E ^a   Yang, Lichuan ^a   Bubber, Parvesh ^a,b   Gibson, Gary E ^a,b   Patel, Mulchand S ^c   Beal, M Flint ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

Author keywords

Alzheimer; Huntington; Mitochondria; Neurodegenerative diseases; Oxidative damage; Parkinson

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3 NITROPROPIONIC ACID; DIHYDROLIPOAMIDE DEHYDROGENASE; MALONIC ACID; MITOCHONDRIAL ENZYME; OXOGLUTARATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; TYROSINE 3 MONOOXYGENASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; BRAIN MITOCHONDRION; CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME SUBUNIT; HUNTINGTON CHOREA; MEMBRANE POTENTIAL; MOUSE; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PUTAMEN; SUBSTANTIA NIGRA; WILD TYPE;

ANIMALIA;

EID: 12144290495     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02263.x     Document Type: Article

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