-
1
-
-
0035818320
-
Neurodegeneration: A failure of neuroregeneration?
-
R.J. Armstrong, and R.A. Barker Neurodegeneration: a failure of neuroregeneration? Lancet 358 2001 1174 1176
-
(2001)
Lancet
, vol.358
, pp. 1174-1176
-
-
Armstrong, R.J.1
Barker, R.A.2
-
2
-
-
0036735672
-
Neuronal replacement from endogenous precursors in the adult brain after stroke
-
A. Arvidsson, T. Collin, D. Kirik, Z. Kokaia, and O. Lindvall Neuronal replacement from endogenous precursors in the adult brain after stroke Nat. Med. 8 2002 963 970
-
(2002)
Nat. Med.
, vol.8
, pp. 963-970
-
-
Arvidsson, A.1
Collin, T.2
Kirik, D.3
Kokaia, Z.4
Lindvall, O.5
-
3
-
-
0035448951
-
Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain
-
A. Benraiss, E. Chmielnicki, K. Lerner, D. Roh, and S.A. Goldman Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain J. Neurosci. 21 2001 6718 6731
-
(2001)
J. Neurosci.
, vol.21
, pp. 6718-6731
-
-
Benraiss, A.1
Chmielnicki, E.2
Lerner, K.3
Roh, D.4
Goldman, S.A.5
-
4
-
-
0034612255
-
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
-
J.A. Bibb, Z. Yan, P. Svenningsson, G.L. Snyder, V.A. Pieribone, A. Horiuchi, A.C. Nairn, A. Messer, and P. Greengard Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice Proc. Natl. Acad. Sci. U. S. A. 297 2000 6809 6814
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.297
, pp. 6809-6814
-
-
Bibb, J.A.1
Yan, Z.2
Svenningsson, P.3
Snyder, G.L.4
Pieribone, V.A.5
Horiuchi, A.6
Nairn, A.C.7
Messer, A.8
Greengard, P.9
-
5
-
-
0042668324
-
Production of new cells in the rat dentate gyrus over the lifespan: Relation to cognitive decline
-
J.L. Bizon, and M. Gallagher Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline Eur. J. Neurosci. 18 2003 215 219
-
(2003)
Eur. J. Neurosci.
, vol.18
, pp. 215-219
-
-
Bizon, J.L.1
Gallagher, M.2
-
6
-
-
20044392282
-
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient β-cell mass
-
M. Björkqvist, M. Fex, N. Wierup, Å. Petersén, J. Gil, K. Bacos, N. Popovic, J.Y. Li, F. Sundler, P. Brundin, and H. Mulder The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient β-cell mass Hum. Mol. Genet. 14 2005 565 574
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 565-574
-
-
Björkqvist, M.1
Fex, M.2
Wierup, N.3
Petersén, Å.4
Gil, J.5
Bacos, K.6
Popovic, N.7
Li, J.Y.8
Sundler, F.9
Brundin, P.10
Mulder, H.11
-
7
-
-
0242300273
-
Transient expression of doublecortin during adult neurogenesis
-
J.P. Brown, S. Couillard-Despres, C.M. Cooper-Kuhn, J. Winkler, L. Aigner, and H.G. Kuhn Transient expression of doublecortin during adult neurogenesis J. Comp. Neurol. 467 2003 1 10
-
(2003)
J. Comp. Neurol.
, vol.467
, pp. 1-10
-
-
Brown, J.P.1
Couillard-Despres, S.2
Cooper-Kuhn, C.M.3
Winkler, J.4
Aigner, L.5
Kuhn, H.G.6
-
8
-
-
4444350918
-
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease
-
J.M. Canals, J.R. Pineda, J.F. Torres-Peraza, M. Bosch, R. Martin-Ibanez, M.T. Munoz, G. Mengod, P. Ernfors, and J. Alberch Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease J. Neurosci. 24 2004 7727 7739
-
(2004)
J. Neurosci.
, vol.24
, pp. 7727-7739
-
-
Canals, J.M.1
Pineda, J.R.2
Torres-Peraza, J.F.3
Bosch, M.4
Martin-Ibanez, R.5
Munoz, M.T.6
Mengod, G.7
Ernfors, P.8
Alberch, J.9
-
9
-
-
0033560924
-
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation
-
R.J. Carter, L.A. Lione, T. Humby, L. Mangiarini, A. Mahal, G.P. Bates, S.B. Dunnett, and A.J. Morton Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation J. Neurosci. 19 1999 3248 3257
-
(1999)
J. Neurosci.
, vol.19
, pp. 3248-3257
-
-
Carter, R.J.1
Lione, L.A.2
Humby, T.3
Mangiarini, L.4
Mahal, A.5
Bates, G.P.6
Dunnett, S.B.7
Morton, A.J.8
-
10
-
-
0034283877
-
Transcriptional dysregulation in Huntington's disease
-
J.H. Cha Transcriptional dysregulation in Huntington's disease Trends Neurosci. 23 2000 387 392
-
(2000)
Trends Neurosci.
, vol.23
, pp. 387-392
-
-
Cha, J.H.1
-
11
-
-
0032568517
-
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
-
J.H. Cha, C.M. Kosinski, J.A. Kerner, S.A. Alsdorf, L. Mangiarini, S.W. Davies, J.B. Penney, G.P. Bates, and A.B. Young Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene Proc. Natl. Acad. Sci. U. S. A. 95 1998 6480 6485
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6480-6485
-
-
Cha, J.H.1
Kosinski, C.M.2
Kerner, J.A.3
Alsdorf, S.A.4
Mangiarini, L.5
Davies, S.W.6
Penney, J.B.7
Bates, G.P.8
Young, A.B.9
-
12
-
-
0037204588
-
Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain
-
C.M. Cooper-Kuhn, and H.G. Kuhn Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain Brain Res. Dev. Brain Res. 134 2002 13 21
-
(2002)
Brain Res. Dev. Brain Res.
, vol.134
, pp. 13-21
-
-
Cooper-Kuhn, C.M.1
Kuhn, H.G.2
-
13
-
-
0042808465
-
Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain
-
M.A. Curtis, E.B. Penney, A.G. Pearson, W.M. van Roon-Mom, N.J. Butterworth, M. Dragunow, B. Connor, and R.L. Faull Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain Proc. Natl. Acad. Sci. U. S. A. 100 2003 9023 9027
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 9023-9027
-
-
Curtis, M.A.1
Penney, E.B.2
Pearson, A.G.3
Van Roon-Mom, W.M.4
Butterworth, N.J.5
Dragunow, M.6
Connor, B.7
Faull, R.L.8
-
14
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
S.W. Davies, M. Turmaine, B.A. Cozens, M. DiFiglia, A.H. Sharp, C.A. Ross, E. Scherzinger, E.E. Wanker, L. Mangiarini, and G.P. Bates Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation Cell 90 1997 537 548
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
Difiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
15
-
-
0038301570
-
Short-term and long-term survival of new neurons in the rat dentate gyrus
-
A.G. Dayer, A.A. Ford, K.M. Cleaver, M. Yassaee, and H.A. Cameron Short-term and long-term survival of new neurons in the rat dentate gyrus J. Comp. Neurol. 460 2003 563 572
-
(2003)
J. Comp. Neurol.
, vol.460
, pp. 563-572
-
-
Dayer, A.G.1
Ford, A.A.2
Cleaver, K.M.3
Yassaee, M.4
Cameron, H.A.5
-
16
-
-
0034762873
-
Regulation of adult neurogenesis by psychotropic drugs and stress
-
R.S. Duman, J. Malberg, and S. Nakagawa Regulation of adult neurogenesis by psychotropic drugs and stress J. Pharmacol. Exp. Ther. 299 2000 401 407
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.299
, pp. 401-407
-
-
Duman, R.S.1
Malberg, J.2
Nakagawa, S.3
-
17
-
-
14344274193
-
In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain
-
J. Fallon, S. Reid, R. Kinyamu, I. Opole, R. Opole, J. Baratta, M. Korc, T.L. Endo, A. Duong, G. Nguyen, M. Karkehabadhi, D. Twardzik, S. Patel, and S. Loughlin In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain Proc. Natl. Acad. Sci. U. S. A. 97 2000 14686 14691
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 14686-14691
-
-
Fallon, J.1
Reid, S.2
Kinyamu, R.3
Opole, I.4
Opole, R.5
Baratta, J.6
Korc, M.7
Endo, T.L.8
Duong, A.9
Nguyen, G.10
Karkehabadhi, M.11
Twardzik, D.12
Patel, S.13
Loughlin, S.14
-
19
-
-
2642545019
-
Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice
-
J.M. Gil, M. Leist, N. Popovic, P. Brundin, and Å. Petersén Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice BMC Neurosci. 5 2004 1 10
-
(2004)
BMC Neurosci.
, vol.5
, pp. 1-10
-
-
Gil, J.M.1
Leist, M.2
Popovic, N.3
Brundin, P.4
Petersén, Å.5
-
20
-
-
0033363319
-
Learning enhances adult neurogenesis in the hippocampal formation
-
E. Gould, A. Beylin, P. Tanapat, A. Reeves, and T.J. Shors Learning enhances adult neurogenesis in the hippocampal formation Nat. Neurosci. 2 1999 260 265
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 260-265
-
-
Gould, E.1
Beylin, A.2
Tanapat, P.3
Reeves, A.4
Shors, T.J.5
-
21
-
-
0023913503
-
Some new, simple and efficient stereological methods and their use in pathological research and diagnosis
-
H.J. Gundersen, T.F. Bendtsen, L. Korbo, N. Marcussen, A. Moller, K. Nielsen, J.R. Nyengaard, B. Pakkenberg, F.B. Sorensen, A. Vesterby, and M.J. West Some new, simple and efficient stereological methods and their use in pathological research and diagnosis APMIS 96 1998 379 394
-
(1998)
APMIS
, vol.96
, pp. 379-394
-
-
Gundersen, H.J.1
Bendtsen, T.F.2
Korbo, L.3
Marcussen, N.4
Moller, A.5
Nielsen, K.6
Nyengaard, J.R.7
Pakkenberg, B.8
Sorensen, F.B.9
Vesterby, A.10
West, M.J.11
-
22
-
-
0036358623
-
Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: Implications for the pathogenesis of Alzheimer's disease
-
N.J. Haughey, D. Liu, A. Nath, A.C. Borchard, and M.P. Mattson Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease Neuromolecular Med. 1 2002 125 135
-
(2002)
Neuromolecular Med.
, vol.1
, pp. 125-135
-
-
Haughey, N.J.1
Liu, D.2
Nath, A.3
Borchard, A.C.4
Mattson, M.P.5
-
23
-
-
0042362874
-
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
-
N.J. Haughey, A. Nath, S.L. Chan, A.C. Borchard, M.S. Rao, and M.P. Mattson Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease J. Neurochem. 83 2002 1509 1524
-
(2002)
J. Neurochem.
, vol.83
, pp. 1509-1524
-
-
Haughey, N.J.1
Nath, A.2
Chan, S.L.3
Borchard, A.C.4
Rao, M.S.5
Mattson, M.P.6
-
24
-
-
0037115495
-
Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice
-
D. Helmlinger, G. Yvert, S. Picaud, K. Merienne, J. Sahel, J.L. Mandel, and D. Devys Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice Hum. Mol. Genet. 11 2002 3351 3359
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 3351-3359
-
-
Helmlinger, D.1
Yvert, G.2
Picaud, S.3
Merienne, K.4
Sahel, J.5
Mandel, J.L.6
Devys, D.7
-
25
-
-
3042822087
-
Dopamine depletion impairs precursor cell proliferation in Parkinson disease
-
G.U. Hoglinger, P. Rizk, M.P. Muriel, C. Duyckaerts, W.H. Oertel, I. Caille, and E.C. Hirsch Dopamine depletion impairs precursor cell proliferation in Parkinson disease Nat. Neurosci. 7 2004 726 735
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 726-735
-
-
Hoglinger, G.U.1
Rizk, P.2
Muriel, M.P.3
Duyckaerts, C.4
Oertel, W.H.5
Caille, I.6
Hirsch, E.C.7
-
26
-
-
0036188984
-
Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice
-
H.P. Huang, K. Chu, E. Nemoz-Gaillard, D. Elberg, and M.J. Tsai Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice Mol. Endocrinol. 16 2002 541 551
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 541-551
-
-
Huang, H.P.1
Chu, K.2
Nemoz-Gaillard, E.3
Elberg, D.4
Tsai, M.J.5
-
27
-
-
0033914470
-
Early alterations in gene expression and cell morphology in a mouse model of Huntington's disease
-
C. Iannicola, S. Moreno, S. Oliverio, R. Nardacci, A. Ciofi-Luzzatto, and M. Piacentini Early alterations in gene expression and cell morphology in a mouse model of Huntington's disease J. Neurochem. 75 2000 830 839
-
(2000)
J. Neurochem.
, vol.75
, pp. 830-839
-
-
Iannicola, C.1
Moreno, S.2
Oliverio, S.3
Nardacci, R.4
Ciofi-Luzzatto, A.5
Piacentini, M.6
-
28
-
-
0346458659
-
Increased hippocampal neurogenesis in Alzheimer's disease
-
K. Jin, A.L. Peel, X.O. Mao, L. Xie, B.A. Cottrell, D.C. Henshall, and D.A. Greenberg Increased hippocampal neurogenesis in Alzheimer's disease Proc. Natl. Acad. Sci. U. S. A. 101 2004 343 347
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 343-347
-
-
Jin, K.1
Peel, A.L.2
Mao, X.O.3
Xie, L.4
Cottrell, B.A.5
Henshall, D.C.6
Greenberg, D.A.7
-
29
-
-
4444269849
-
Enhanced neurogenesis in Alzheimer's disease transgenic mice
-
K. Jin, V. Galvan, L. Xie, X.O. Mao, O.F. Gorostiza, D.E. Bredesen, and D.A. Greenberg Enhanced neurogenesis in Alzheimer's disease transgenic mice Proc. Natl. Acad. Sci. U. S. A. 101 2004 13363 13367
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 13363-13367
-
-
Jin, K.1
Galvan, V.2
Xie, L.3
Mao, X.O.4
Gorostiza, O.F.5
Bredesen, D.E.6
Greenberg, D.A.7
-
30
-
-
0037196872
-
The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis
-
N. Kee, S. Sivalingam, R. Boonstra, and J.M. Wojtowicz The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis J. Neurosci. Methods 115 2002 97 105
-
(2002)
J. Neurosci. Methods
, vol.115
, pp. 97-105
-
-
Kee, N.1
Sivalingam, S.2
Boonstra, R.3
Wojtowicz, J.M.4
-
32
-
-
1842608950
-
Decreased hippocampal cell proliferation in R6/1 Huntington's mice
-
S.E. Lazic, H. Grote, R.J. Armstrong, C. Blakemore, A.J. Hannan, A. van Dellen, and R.A. Barker Decreased hippocampal cell proliferation in R6/1 Huntington's mice NeuroReport 15 2004 811 813
-
(2004)
NeuroReport
, vol.15
, pp. 811-813
-
-
Lazic, S.E.1
Grote, H.2
Armstrong, R.J.3
Blakemore, C.4
Hannan, A.J.5
Van Dellen, A.6
Barker, R.A.7
-
33
-
-
1242338856
-
Huntingtin-protein interactions and the pathogenesis of Huntington's disease
-
S.H. Li, and X.J. Li Huntingtin-protein interactions and the pathogenesis of Huntington's disease Trends Genet. 20 2004 146 154
-
(2004)
Trends Genet.
, vol.20
, pp. 146-154
-
-
Li, S.H.1
Li, X.J.2
-
34
-
-
0346868807
-
Neurogenesis in the adult brain: New strategies for central nervous system diseases
-
D.C. Lie, H. Song, S.A. Colamarino, G.L. Ming, and F.H. Gage Neurogenesis in the adult brain: new strategies for central nervous system diseases Annu. Rev. Pharmacol. Toxicol. 44 2004 399 421
-
(2004)
Annu. Rev. Pharmacol. Toxicol.
, vol.44
, pp. 399-421
-
-
Lie, D.C.1
Song, H.2
Colamarino, S.A.3
Ming, G.L.4
Gage, F.H.5
-
35
-
-
0033500593
-
Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation
-
L.A. Lione, R.J. Carter, M.J. Hunt, G.P. Bates, A.J. Morton, and S.B. Dunnett Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation J. Neurosci. 19 1999 10428 10437
-
(1999)
J. Neurosci.
, vol.19
, pp. 10428-10437
-
-
Lione, L.A.1
Carter, R.J.2
Hunt, M.J.3
Bates, G.P.4
Morton, A.J.5
Dunnett, S.B.6
-
36
-
-
0034681192
-
Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy
-
M. Liu, S.J. Pleasure, A.E. Collins, J.L. Noebels, F.J. Naya, M.J. Tsai, and D.H. Lowenstein Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy Proc. Natl. Acad. Sci. U. S. A. 97 2000 865 870
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 865-870
-
-
Liu, M.1
Pleasure, S.J.2
Collins, A.E.3
Noebels, J.L.4
Naya, F.J.5
Tsai, M.J.6
Lowenstein, D.H.7
-
37
-
-
0034702030
-
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
R. Luthi-Carter, A. Strand, N.L. Peters, S.M. Solano, Z.R. Hollingsworth, A.S. Menon, A.S. Frey, B.S. Spektor, E.B. Penney, G. Schilling, C.A. Ross, D.R. Borchelt, S.J. Tapscott, A.B. Young, J.H. Cha, and J.M. Olson Decreased expression of striatal signaling genes in a mouse model of Huntington's disease Hum. Mol. Genet. 9 2000 1259 1271
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
Ross, C.A.11
Borchelt, D.R.12
Tapscott, S.J.13
Young, A.B.14
Cha, J.H.15
Olson, J.M.16
-
38
-
-
0037101835
-
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain
-
R. Luthi-Carter, S.A. Hanson, A.D. Strand, D.A. Bergstrom, W. Chun, N.L. Peters, A.M. Woods, E.Y. Chan, C. Kooperberg, D. Krainc, A.B. Young, S.J. Tapscott, and J.M. Olson Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain Hum. Mol. Genet. 11 2002 1911 1926
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1911-1926
-
-
Luthi-Carter, R.1
Hanson, S.A.2
Strand, A.D.3
Bergstrom, D.A.4
Chun, W.5
Peters, N.L.6
Woods, A.M.7
Chan, E.Y.8
Kooperberg, C.9
Krainc, D.10
Young, A.B.11
Tapscott, S.J.12
Olson, J.M.13
-
39
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
L. Mangiarini, K. Sathasivam, M. Seller, B. Cozens, A. Harper, C. Hetherington, M. Lawton, Y. Trottier, H. Lehrach, S.W. Davies, and G.P. Bates Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice Cell 87 1996 493 506
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
40
-
-
0031056685
-
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation
-
L. Mangiarini, K. Sathasivam, A. Mahal, R. Mott, M. Seller, and G.P. Bates Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation Nat. Genet. 15 1997 197 200
-
(1997)
Nat. Genet.
, vol.15
, pp. 197-200
-
-
Mangiarini, L.1
Sathasivam, K.2
Mahal, A.3
Mott, R.4
Seller, M.5
Bates, G.P.6
-
41
-
-
0042423684
-
Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2
-
E. Marcora, K. Gowan, and J.E. Lee Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2 Proc. Natl. Acad. Sci. U. S. A. 100 2003 9578 9583
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 9578-9583
-
-
Marcora, E.1
Gowan, K.2
Lee, J.E.3
-
42
-
-
2942541217
-
Harnessing endogenous stem cells to treat neurodegenerative disorders of the basal ganglia
-
P. Mohapel, and P. Brundin Harnessing endogenous stem cells to treat neurodegenerative disorders of the basal ganglia Parkinsonism Relat. Disord. 10 2004 259 264
-
(2004)
Parkinsonism Relat. Disord.
, vol.10
, pp. 259-264
-
-
Mohapel, P.1
Brundin, P.2
-
43
-
-
0034234519
-
Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease gene
-
K.P. Murphy, R.J. Carter, L.A. Lione, L. Mangiarini, A. Mahal, G.P. Bates, S.B. Dunnett, and A.J. Morton Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease gene J. Neurosci. 20 2000 5115 5123
-
(2000)
J. Neurosci.
, vol.20
, pp. 5115-5123
-
-
Murphy, K.P.1
Carter, R.J.2
Lione, L.A.3
Mangiarini, L.4
Mahal, A.5
Bates, G.P.6
Dunnett, S.B.7
Morton, A.J.8
-
44
-
-
0036895463
-
Rat forebrain neurogenesis and striatal neuron replacement after focal stroke
-
J.M. Parent, Z.S. Vexler, C. Gong, N. Derugin, and D.M. Ferriero Rat forebrain neurogenesis and striatal neuron replacement after focal stroke Ann. Neurol. 52 2002 802 813
-
(2002)
Ann. Neurol.
, vol.52
, pp. 802-813
-
-
Parent, J.M.1
Vexler, Z.S.2
Gong, C.3
Derugin, N.4
Ferriero, D.M.5
-
45
-
-
0035449745
-
Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus
-
V. Pencea, K.D. Bingaman, S.J. Wiegand, and M.B. Luskin Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus J. Neurosci. 21 2001 6706 6717
-
(2001)
J. Neurosci.
, vol.21
, pp. 6706-6717
-
-
Pencea, V.1
Bingaman, K.D.2
Wiegand, S.J.3
Luskin, M.B.4
-
46
-
-
0036983035
-
Huntington's disease: The mystery unfolds?
-
Å. Petersén, and P. Brundin Huntington's disease: the mystery unfolds? Int. Rev. Neorobiol. 53 2002 315 339
-
(2002)
Int. Rev. Neorobiol.
, vol.53
, pp. 315-339
-
-
Petersén, Å.1
Brundin, P.2
-
47
-
-
0036453663
-
Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice
-
Å. Petersén, Z. Puschban, J. Lotharius, B. NicNiocaill, P. Wiekop, W.T. O'Connor, and P. Brundin Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice Neurobiol. Dis. 11 2002 134 146
-
(2002)
Neurobiol. Dis.
, vol.11
, pp. 134-146
-
-
Petersén, Å.1
Puschban, Z.2
Lotharius, J.3
Nicniocaill, B.4
Wiekop, P.5
O'Connor, W.T.6
Brundin, P.7
-
48
-
-
19944427749
-
Orexin loss in Huntington's disease
-
Å. Petersén, J. Gil, M.L.C. Maat-Schieman, M. Björkqvist, H. Tanila, I.M. Araújo, R. Smith, N. Popovic, N. Wierup, P. Norlén, J.-Y. Li, R.A.C. Roos, F. Sundler, H. Mulder, and P. Brundin Orexin loss in Huntington's disease Hum. Mol. Genet. 14 2005 39 47
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 39-47
-
-
Petersén, Å.1
Gil, J.2
Maat-Schieman, M.L.C.3
Björkqvist, M.4
Tanila, H.5
Araújo, I.M.6
Smith, R.7
Popovic, N.8
Wierup, N.9
Norlén, P.10
Li, J.-Y.11
Roos, R.A.C.12
Sundler, F.13
Mulder, H.14
Brundin, P.15
-
49
-
-
0038476184
-
Evidence for more widespread cerebral pathology in early HD: An MRI-based morphometric analysis
-
H.D. Rosas, W.J. Koroshetz, Y.I. Chen, C. Skeuse, M. Vangel, M.E. Cudkowicz, K. Caplan, K. Marek, L.J. Seidman, N. Makris, B.G. Jenkins, and J.M. Goldstein Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis Neurology 60 2003 1615 1620
-
(2003)
Neurology
, vol.60
, pp. 1615-1620
-
-
Rosas, H.D.1
Koroshetz, W.J.2
Chen, Y.I.3
Skeuse, C.4
Vangel, M.5
Cudkowicz, M.E.6
Caplan, K.7
Marek, K.8
Seidman, L.J.9
Makris, N.10
Jenkins, B.G.11
Goldstein, J.M.12
-
50
-
-
1542286877
-
Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism
-
T.L. Spires, H.E. Grote, N.K. Varshney, P.M. Cordery, A. van Dellen, C. Blakemore, and A.J. Hannan Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism J. Neurosci. 24 2004 2270 2276
-
(2004)
J. Neurosci.
, vol.24
, pp. 2270-2276
-
-
Spires, T.L.1
Grote, H.E.2
Varshney, N.K.3
Cordery, P.M.4
Van Dellen, A.5
Blakemore, C.6
Hannan, A.J.7
-
51
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group
-
The Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes Cell 72 1993 971 983
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
52
-
-
0032189274
-
Changes in proliferating cell nuclear antigen, a protein involved in DNA repair, in vulnerable hippocampal neurons following global cerebral ischemia
-
G. Tomasevic, F. Kamme, and T. Wieloch Changes in proliferating cell nuclear antigen, a protein involved in DNA repair, in vulnerable hippocampal neurons following global cerebral ischemia Brain Res. Mol. Brain Res. 60 1998 168 176
-
(1998)
Brain Res. Mol. Brain Res.
, vol.60
, pp. 168-176
-
-
Tomasevic, G.1
Kamme, F.2
Wieloch, T.3
-
53
-
-
0034608857
-
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
-
M. Turmaine, A. Raza, A. Mahal, L. Mangiarini, G.P. Bates, and S.W. Davies Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease Proc. Natl. Acad. Sci. U. S. A. 97 2000 8093 8097
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 8093-8097
-
-
Turmaine, M.1
Raza, A.2
Mahal, A.3
Mangiarini, L.4
Bates, G.P.5
Davies, S.W.6
-
54
-
-
0037186524
-
Functional neurogenesis in the adult hippocampus
-
H. van Praag, A.F. Schinder, B.R. Christie, N. Toni, T.D. Palmer, and F.H. Gage Functional neurogenesis in the adult hippocampus Nature 415 2002 1030 1034
-
(2002)
Nature
, vol.415
, pp. 1030-1034
-
-
Van Praag, H.1
Schinder, A.F.2
Christie, B.R.3
Toni, N.4
Palmer, T.D.5
Gage, F.H.6
-
56
-
-
0029895292
-
Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease
-
R.A. Weeks, P. Piccini, A.E. Harding, and D.J. Brooks Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease Ann. Neurol. 40 1996 49 54
-
(1996)
Ann. Neurol.
, vol.40
, pp. 49-54
-
-
Weeks, R.A.1
Piccini, P.2
Harding, A.E.3
Brooks, D.J.4
-
57
-
-
0142153442
-
Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology
-
G.J. Yohrling IV, G.C. Jiang, M.M. DeJohn, D.W. Miller, A.B. Young, K.E. Vrana, and J.H. Cha Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology Brain Res. Mol. Brain Res. 119 2003 28 36
-
(2003)
Brain Res. Mol. Brain Res.
, vol.119
, pp. 28-36
-
-
Yohrling IV, G.J.1
Jiang, G.C.2
Dejohn, M.M.3
Miller, D.W.4
Young, A.B.5
Vrana, K.E.6
Cha, J.H.7
-
58
-
-
0038037721
-
Evidence for neurogenesis in the adult mammalian substantia nigra
-
M. Zhao, S. Momma, K. Delfani, M. Carlen, R.M. Cassidy, C.B. Johansson, H. Brismar, O. Shupliakov, J. Frisen, and AM. Janson Evidence for neurogenesis in the adult mammalian substantia nigra Proc. Natl. Acad. Sci. U. S. A. 100 2003 7925 7930
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 7925-7930
-
-
Zhao, M.1
Momma, S.2
Delfani, K.3
Carlen, M.4
Cassidy, R.M.5
Johansson, C.B.6
Brismar, H.7
Shupliakov, O.8
Frisen, J.9
Janson, A.M.10
-
59
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
C. Zuccato, A. Ciammola, D. Rigamonti, B.R. Leavitt, D. Goffredo, L. Conti, M.E. MacDonald, R.M. Friedlander, V. Silani, M.R. Hayden, T. Timmusk, S. Sipione, and E. Cattaneo Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease Science 293 2001 493 498
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
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