-
2
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group 10.1016/ 0092-8674(93)90585-E 8458085
-
Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is unstable on Huntington's disease chromosomes Cell 1993 72:971-983 10.1016/0092-8674(93)90585-E 8458085
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
3
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
10.1016/S0092-8674(00)81369-0 8898202
-
Mangiarini L Sathasivam K Seller M Cozens B Harper A Hetherington C Lawton M Trottier Y Lehrach H Davies SW Bates GP Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice Cell 1996 87:493-506 10.1016/ S0092-8674(00)81369-0 8898202
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
4
-
-
0033614761
-
Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease
-
1692608 10434296 10.1098/rstb.1999.0449
-
Cha JH Frey AS Alsdorf SA Kerner JA Kosinski CM Mangiarini L Penney JB Davies SW Bates GP Young AB Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease Philos Trans R Soc Lond B Biol Sci 1999 354:981-989 1692608 10434296 10.1098/rstb.1999.0449
-
(1999)
Philos Trans R Soc Lond B Biol Sci
, vol.354
, pp. 981-989
-
-
Cha, J.H.1
Frey, A.S.2
Alsdorf, S.A.3
Kerner, J.A.4
Kosinski, C.M.5
Mangiarini, L.6
Penney, J.B.7
Davies, S.W.8
Bates, G.P.9
Young, A.B.10
-
5
-
-
0033587760
-
Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal exctitotoxicity
-
17584 10.1073/pnas.96.15.8727
-
Hansson O Petersen A Leist M Nicotera P Castilho RF Brundin P Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal exctitotoxicity Proc Natl Acad Sci USA 1999 96:8727-8732 17584 10411943 10.1073/pnas.96.15.8727
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8727-8732
-
-
Hansson, O.1
Petersen, A.2
Leist, M.3
Nicotera, P.4
Castilho, R.F.5
Brundin, P.6
-
7
-
-
0034722642
-
N-Acetylaspartate and DARPP-32 levels decrease in the corpus striatum of Huntington's disease mice
-
10.1097/00001756-200011270-00032 11117485
-
Van Dellen A Welch J Dixon RM Cordery P York D Styles P Blakemore C Hannan AJ N-Acetylaspartate and DARPP-32 levels decrease in the corpus striatum of Huntington's disease mice Neuroreport 2000 11:3751-3757 10.1097/00001756-200011270-00032 11117485
-
(2000)
Neuroreport
, vol.11
, pp. 3751-3757
-
-
Van Dellen, A.1
Welch, J.2
Dixon, R.M.3
Cordery, P.4
York, D.5
Styles, P.6
Blakemore, C.7
Hannan, A.J.8
-
8
-
-
1542286877
-
Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism
-
10.1523/JNEUROSCI.1658-03.2004 14999077
-
Spires TL Grote HE Varshney NK Cordery PM van Dellen A Blakemore C Hannan AJ Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism J Neurosci 2004 24:2270-2276 10.1523/JNEUROSCI.1658-03.2004 14999077
-
(2004)
J Neurosci
, vol.24
, pp. 2270-2276
-
-
Spires, T.L.1
Grote, H.E.2
Varshney, N.K.3
Cordery, P.M.4
van Dellen, A.5
Blakemore, C.6
Hannan, A.J.7
-
9
-
-
2942620844
-
Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice
-
10.1111/j.0953-816X.2004.03374.x 15147313
-
Spires TL Grote HE Garry S Cordery PM Van Dellen A Blakemore C Hannan AJ Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice Eur J Neurosci 2004 19:2799-2807 10.1111/j.0953-816X.2004.03374.x 15147313
-
(2004)
Eur J Neurosci
, vol.19
, pp. 2799-2807
-
-
Spires, T.L.1
Grote, H.E.2
Garry, S.3
Cordery, P.M.4
Van Dellen, A.5
Blakemore, C.6
Hannan, A.J.7
-
10
-
-
33747613561
-
Enriched environments, experience-dependent plasticity and disorders of the nervous system
-
10.1038/nrn1970 16924259
-
Nithianantharajah J Hannan AJ Enriched environments, experience-dependent plasticity and disorders of the nervous system Nature Rev Neurosci 2006 7(9):697-709 10.1038/nrn1970 16924259
-
(2006)
Nature Rev Neurosci
, vol.7
, Issue.9
, pp. 697-709
-
-
Nithianantharajah, J.1
Hannan, A.J.2
-
11
-
-
0036152343
-
Environmental enrichment slows disease progression in R6/2 Huntington's disease mice
-
10.1002/ana.10094 11835380
-
Hockly E Cordery PM Woodman B Mahal A Van Dellen A Blakemore C Lewis CM Hannan AJ Bates GP Environmental enrichment slows disease progression in R6/2 Huntington's disease mice Ann Neurol 2002 51:235-242 10.1002/ ana.10094 11835380
-
(2002)
Ann Neurol
, vol.51
, pp. 235-242
-
-
Hockly, E.1
Cordery, P.M.2
Woodman, B.3
Mahal, A.4
Van Dellen, A.5
Blakemore, C.6
Lewis, C.M.7
Hannan, A.J.8
Bates, G.P.9
-
12
-
-
0034608857
-
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
-
16675 10.1073/pnas.110078997
-
Turmaine M Raza A Mahal A Mangiarini L Bates GP Davies SW Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease Proc Natl Acad Sci USA 2000 97:8093-8097 16675 10869421 10.1073/ pnas.110078997
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8093-8097
-
-
Turmaine, M.1
Raza, A.2
Mahal, A.3
Mangiarini, L.4
Bates, G.P.5
Davies, S.W.6
-
13
-
-
0035503912
-
Anterior cingulate cortical transplantation in transgenic Huntington's disease mice
-
10.1016/S0361-9230(01)00655-4 11719266
-
van Dellen A Deacon R York D Blakemore C Hannan AJ Anterior cingulate cortical transplantation in transgenic Huntington's disease mice Brain Res Bull 2001 56:313-318 10.1016/S0361-9230(01)00655-4 11719266
-
(2001)
Brain Res Bull
, vol.56
, pp. 313-318
-
-
van Dellen, A.1
Deacon, R.2
York, D.3
Blakemore, C.4
Hannan, A.J.5
-
14
-
-
33745979171
-
Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice
-
10.1016/j.neuroscience.2006.04.013 16716524
-
Pang TY Stam NC Nithianantharajah J Howard ML Hannan AJ Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice Neuroscience 2006 141:569-584 10.1016/ j.neuroscience.2006.04.013 16716524
-
(2006)
Neuroscience
, vol.141
, pp. 569-584
-
-
Pang, T.Y.1
Stam, N.C.2
Nithianantharajah, J.3
Howard, M.L.4
Hannan, A.J.5
-
15
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
10.1126/science.277.5334.1990 9302293
-
DiFiglia M Sapp E Chase KO Davies SW Bates GP Vonsattel JP Aronin N Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain Science 1997 277:1990-1993 10.1126/ science.277.5334.1990 9302293
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
16
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
10.1016/S0092-8674(00)80513-9 9267033
-
Davies SW Turmaine M Cozens BA DiFiglia M Sharp AH Ross CA Scherzinger E Wanker EE Mangiarini L Bates GP Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation Cell 1997 90:537-548 10.1016/S0092-8674(00)80513-9 9267033
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
17
-
-
11144358364
-
Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice
-
10.1016/j.expneurol.2004.01.003 15081595
-
Schilling G Savonenko AV Coonfield ML Morton JL Vorovich E Gale A Neslon C Chan N Eaton M Fromholt D Ross CA Borchelt DR Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice Exp Neurol 2004 187:137-149 10.1016/ j.expneurol.2004.01.003 15081595
-
(2004)
Exp Neurol
, vol.187
, pp. 137-149
-
-
Schilling, G.1
Savonenko, A.V.2
Coonfield, M.L.3
Morton, J.L.4
Vorovich, E.5
Gale, A.6
Neslon, C.7
Chan, N.8
Eaton, M.9
Fromholt, D.10
Ross, C.A.11
Borchelt, D.R.12
-
18
-
-
39249084983
-
Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice
-
18165017 10.1016/j.nbd.2007.11.006
-
Nithianantharajah AJ Barkus C Murphy M Hannan AJ Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice Neurobiology of Disease 2008 29:490-504 18165017 10.1016/j.nbd.2007.11.006
-
(2008)
Neurobiology of Disease
, vol.29
, pp. 490-504
-
-
Nithianantharajah, A.J.1
Barkus, C.2
Murphy, M.3
Hannan, A.J.4
-
19
-
-
0032568517
-
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
-
27817 9600992 10.1073/pnas.95.11.6480
-
Cha JH Kosinski CM Kerner JA Alsdorf SA Mangiarini L Davies SW Penney JB Bates GP Young AB Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene Proc Natl Acad Sci USA 1998 95:6480-6485 27817 9600992 10.1073/ pnas.95.11.6480
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6480-6485
-
-
Cha, J.H.1
Kosinski, C.M.2
Kerner, J.A.3
Alsdorf, S.A.4
Mangiarini, L.5
Davies, S.W.6
Penney, J.B.7
Bates, G.P.8
Young, A.B.9
-
20
-
-
0034702030
-
Decreased expression of striatal signalling genes in a mouse model of Huntington's disease
-
10.1093/hmg/9.9.1259 10814708
-
Luthi-Carter R Strand A Peters NL Solano SM Hollingsworth ZR Menon AS Frey AS Spektor BS Penney EB Schilling G Ross CA Borchelt DR Tapscott SJ Young AB Cha JH Olson JM Decreased expression of striatal signalling genes in a mouse model of Huntington's disease Hum Mol Genet 2000 9:1259-1271 10.1093/hmg/9.9.1259 10814708
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
Ross, C.A.11
Borchelt, D.R.12
Tapscott, S.J.13
Young, A.B.14
Cha, J.H.15
Olson, J.M.16
-
21
-
-
34547839797
-
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage
-
10.1093/hmg/ddm133 17519223
-
Kuhn A Goldstein DR Hodges A Strand AD Sengstag T Kooperberg C Becanovic K Pouladi MA Sathasivam K Cha JH Hannan AJ Hayden MR Leavitt BR Dunnett SB Ferrante RJ Albin R Shelbourne P Delorenzi M Augood SJ Faull RL Olson JM Bates GP Jones L Luthi-Carter R Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage Hum Mol Genet 2007 16:1845-61 10.1093/hmg/ddm133 17519223
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1845-1861
-
-
Kuhn, A.1
Goldstein, D.R.2
Hodges, A.3
Strand, A.D.4
Sengstag, T.5
Kooperberg, C.6
Becanovic, K.7
Pouladi, M.A.8
Sathasivam, K.9
Cha, J.H.10
Hannan, A.J.11
Hayden, M.R.12
Leavitt, B.R.13
Dunnett, S.B.14
Ferrante, R.J.15
Albin, R.16
Shelbourne, P.17
Delorenzi, M.18
Augood, S.J.19
Faull, R.L.20
Olson, J.M.21
Bates, G.P.22
Jones, L.23
Luthi-Carter, R.24
more..
-
22
-
-
0034081681
-
The pattern of neurodegeneration in Huntington's disease: A comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease
-
10.1016/S0306-4522(00)00008-7 10828533
-
Glass M Dragunow M Faull RL The pattern of neurodegeneration in Huntington's disease: A comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease Neuroscience 2000 97:505-519 10.1016/ S0306-4522(00)00008-7 10828533
-
(2000)
Neuroscience
, vol.97
, pp. 505-519
-
-
Glass, M.1
Dragunow, M.2
Faull, R.L.3
-
23
-
-
0345118102
-
Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors
-
10.1016/S0306-4522(03)00595-5 14667455
-
Glass M van Dellen A Blakemore C Hannan AJ Faull RL Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors Neuroscience 2004 123:207-212 10.1016/S0306-4522(03)00595-5 14667455
-
(2004)
Neuroscience
, vol.123
, pp. 207-212
-
-
Glass, M.1
van Dellen, A.2
Blakemore, C.3
Hannan, A.J.4
Faull, R.L.5
-
24
-
-
0034595722
-
Brain-derived neurotrophic factor in Huntington disease
-
10.1016/S0006-8993(00)02237-X 10825501
-
Ferrer I Goutan E Marin C Rey MJ Ribalta T Brain-derived neurotrophic factor in Huntington disease Brain Res 2000 866:257-261 10.1016/ S0006-8993(00)02237-X 10825501
-
(2000)
Brain Res
, vol.866
, pp. 257-261
-
-
Ferrer, I.1
Goutan, E.2
Marin, C.3
Rey, M.J.4
Ribalta, T.5
-
25
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
11408619
-
Zuccato C Ciammola A Rigamonti D Leavitt BR Goffredo D Conti L MacDonald ME Friedlander RM Silani V Hayden MR Timmusk T Sipione S Cattaneo E Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease Scienc 2001 293:5529-493 498 11408619
-
(2001)
Scienc
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
-
26
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
10.1038/ng1219 12881722
-
Zuccato C Tartari M Crotti A Goffredo D Valenza M Conti L Cataudella T Leavitt BR Hayden MR Timmusk T Rigamonti D Cattaneo E Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes Nat Genet 2003 35:76-83 10.1038/ng1219 12881722
-
(2003)
Nat Genet
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
Cataudella, T.7
Leavitt, B.R.8
Hayden, M.R.9
Timmusk, T.10
Rigamonti, D.11
Cattaneo, E.12
-
27
-
-
4444350918
-
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease
-
10.1523/JNEUROSCI.1197-04.2004 15342740
-
Canals JM Pineda JR Torres-Peraza JF Bosch M Martin-Ibanez R Munoz MT Mengod G Ernfors P Alberch J Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease J Neurosci 2004 24:7727-7739 10.1523/JNEUROSCI.1197-04.2004 15342740
-
(2004)
J Neurosci
, vol.24
, pp. 7727-7739
-
-
Canals, J.M.1
Pineda, J.R.2
Torres-Peraza, J.F.3
Bosch, M.4
Martin-Ibanez, R.5
Munoz, M.T.6
Mengod, G.7
Ernfors, P.8
Alberch, J.9
-
28
-
-
10644241634
-
Increased GABAergic function in mouse models of Huntington's disease: Reversal by BDNF
-
10.1002/jnr.20344 15505789
-
Cepeda C Starling AJ Wu N Nguyen OK Uzgil B Soda T Andre VM Ariano MA Levine MS Increased GABAergic function in mouse models of Huntington's disease: Reversal by BDNF J Neurosci Res 2004 78:855-867 10.1002/ jnr.20344 15505789
-
(2004)
J Neurosci Res
, vol.78
, pp. 855-867
-
-
Cepeda, C.1
Starling, A.J.2
Wu, N.3
Nguyen, O.K.4
Uzgil, B.5
Soda, T.6
Andre, V.M.7
Ariano, M.A.8
Levine, M.S.9
-
29
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
10.1016/j.cell.2004.06.018 15242649
-
Gauthier LR Charrin BC Borrell-Pages M Dompierre JP Rangone H Cordelieres FP De Mey J MacDonald ME Lessmann V Humbert S Saudou F Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules Cell 2004 118:127-138 10.1016/j.cell.2004.06.018 15242649
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
Charrin, B.C.2
Borrell-Pages, M.3
Dompierre, J.P.4
Rangone, H.5
Cordelieres, F.P.6
De Mey, J.7
MacDonald, M.E.8
Lessmann, V.9
Humbert, S.10
Saudou, F.11
-
30
-
-
34047180648
-
The corticostriatal pathway in Huntington's disease
-
1913635 10.1016/j.pneurobio.2006.11.001
-
Cepeda C Wu N Andre VM Cummings DM Levine MS The corticostriatal pathway in Huntington's disease Prog Neurobiol 2007 81:253-271 1913635 17169479 10.1016/j.pneurobio.2006.11.001
-
(2007)
Prog Neurobiol
, vol.81
, pp. 253-271
-
-
Cepeda, C.1
Wu, N.2
Andre, V.M.3
Cummings, D.M.4
Levine, M.S.5
-
31
-
-
33745192028
-
Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease
-
10.1093/hmg/ddl092 16600988
-
Milnerwood AJ Cummings DM Dallerac GM Brown JY Vatsavayai SC Hirst MC Rezaie P Murphy KP Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease Hum Mol Genet 2006 15:1690-703 10.1093/hmg/ddl092 16600988
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1690-1703
-
-
Milnerwood, A.J.1
Cummings, D.M.2
Dallerac, G.M.3
Brown, J.Y.4
Vatsavayai, S.C.5
Hirst, M.C.6
Rezaie, P.7
Murphy, K.P.8
-
32
-
-
0034234519
-
Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation
-
10864968
-
Murphy KP Carter RJ Lione LA Mangiarini L Mahal A Bates GP Dunnett SB Morton AJ Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation J Neurosci 2000 20:5115-5123 10864968
-
(2000)
J Neurosci
, vol.20
, pp. 5115-5123
-
-
Murphy, K.P.1
Carter, R.J.2
Lione, L.A.3
Mangiarini, L.4
Mahal, A.5
Bates, G.P.6
Dunnett, S.B.7
Morton, A.J.8
-
33
-
-
0033136692
-
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration
-
10.1016/S0896-6273(00)80764-3 10402204
-
Hodgson JG Agopyan N Gutekunst CA Leavitt BR LePiane F Singaraja R Smith DJ Bissada N McCutcheon K Nasir J Jamot L Li XJ Stevens ME Rosemond E Roder JC Phillips AG Rubin EM Hersch SM Hayden MR A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration Neuron 1999 23:181-192 10.1016/S0896-6273(00)80764-3 10402204
-
(1999)
Neuron
, vol.23
, pp. 181-192
-
-
Hodgson, J.G.1
Agopyan, N.2
Gutekunst, C.A.3
Leavitt, B.R.4
LePiane, F.5
Singaraja, R.6
Smith, D.J.7
Bissada, N.8
McCutcheon, K.9
Nasir, J.10
Jamot, L.11
Li, X.J.12
Stevens, M.E.13
Rosemond, E.14
Roder, J.C.15
Phillips, A.G.16
Rubin, E.M.17
Hersch, S.M.18
Hayden, M.R.19
-
34
-
-
0032897760
-
Impaired synaptic plasticity in mice carrying the Huntington's disease mutation
-
10.1093/hmg/8.5.839 10196373
-
Usdin MT Shelbourne PF Myers RM Madison DV Impaired synaptic plasticity in mice carrying the Huntington's disease mutation Hum Mol Genet 1999 8:839-846 10.1093/hmg/8.5.839 10196373
-
(1999)
Hum Mol Genet
, vol.8
, pp. 839-846
-
-
Usdin, M.T.1
Shelbourne, P.F.2
Myers, R.M.3
Madison, D.V.4
-
35
-
-
33749009774
-
Aberrant cortical synaptic plasticity and dopaminergic dysfunction in a mouse model of Huntington's disease
-
10.1093/hmg/ddl224 16905556
-
Cummings DM Milnerwood AJ Dallerac GM Waights V Brown JY Vatsavayai SC Hirst MC Murphy KP Aberrant cortical synaptic plasticity and dopaminergic dysfunction in a mouse model of Huntington's disease Hum Mol Genet 2006 15:2856-68 10.1093/hmg/ddl224 16905556
-
(2006)
Hum Mol Genet
, vol.15
, pp. 2856-2868
-
-
Cummings, D.M.1
Milnerwood, A.J.2
Dallerac, G.M.3
Waights, V.4
Brown, J.Y.5
Vatsavayai, S.C.6
Hirst, M.C.7
Murphy, K.P.8
-
37
-
-
16244392082
-
Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice
-
10.1523/JNEUROSCI.4320-04.2005 15788762
-
Mazarakis NK Cybulska-Klosowicz A Grote H Pang T Van Dellen A Kossut M Blakemore C Hannan AJ Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice J Neurosci 2005 25:3059-3060 10.1523/ JNEUROSCI.4320-04.2005 15788762
-
(2005)
J Neurosci
, vol.25
, pp. 3059-3060
-
-
Mazarakis, N.K.1
Cybulska-Klosowicz, A.2
Grote, H.3
Pang, T.4
Van Dellen, A.5
Kossut, M.6
Blakemore, C.7
Hannan, A.J.8
-
38
-
-
0030583619
-
Mechanism of altered synaptic strength due to experience: Relation to long-term potentiation
-
10.1016/0006-8993(96)00707-X 8930330
-
Foster TC Gagne J Massicotte G Mechanism of altered synaptic strength due to experience: Relation to long-term potentiation Brain Res 1996 736:243-250 10.1016/0006-8993(96)00707-X 8930330
-
(1996)
Brain Res
, vol.736
, pp. 243-250
-
-
Foster, T.C.1
Gagne, J.2
Massicotte, G.3
-
39
-
-
0033539607
-
Running enhances neurogenesis, learning, and long-term potentiation in mice
-
23964 10557337 10.1073/pnas.96.23.13427
-
van Praag H Christie BR Sejnowski TJ Gage FH Running enhances neurogenesis, learning, and long-term potentiation in mice Proc Natl Acad Sci USA 1999 96:13427-13431 23964 10557337 10.1073/pnas.96.23.13427
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13427-13431
-
-
van Praag, H.1
Christie, B.R.2
Sejnowski, T.J.3
Gage, F.H.4
-
41
-
-
27644524469
-
Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine
-
10.1111/j.1460-9568.2005.04365.x 16262645
-
Grote HE Bull ND Howard ML van Dellen A Blakemore C Bartlett PF Hannan AJ Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine Eur J Neurosci 2005 22(8):2081-2008 10.1111/j.1460-9568.2005.04365.x 16262645
-
(2005)
Eur J Neurosci
, vol.22
, Issue.1
, pp. 2008-2081
-
-
Grote, H.E.1
Bull, N.D.2
Howard, M.L.3
van Dellen, A.4
Blakemore, C.5
Bartlett, P.F.6
Hannan, A.J.7
-
42
-
-
2642545019
-
Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice
-
434499 10.1186/1471-2202-5-17
-
Gil JM Leist M Popovic N Brundin P Petersen A Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice BMC Neurosci 2004 5:17 434499 15134587 10.1186/1471-2202-5-17
-
(2004)
BMC Neurosci
, vol.5
, pp. 17
-
-
Gil, J.M.1
Leist, M.2
Popovic, N.3
Brundin, P.4
Petersen, A.5
-
44
-
-
33645452859
-
Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: Effects of environmental enrichment
-
10.1111/j.1460-9568.2006.04715.x 16623840
-
Lazic SE Grote HE Blakemore C Hannan AJ van Dellen A Phillips W Barker RA Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: Effects of environmental enrichment Eur J Neurosci 2006 23:1829-1838 10.1111/j.1460-9568.2006.04715.x 16623840
-
(2006)
Eur J Neurosci
, vol.23
, pp. 1829-1838
-
-
Lazic, S.E.1
Grote, H.E.2
Blakemore, C.3
Hannan, A.J.4
van Dellen, A.5
Phillips, W.6
Barker, R.A.7
-
45
-
-
0033360314
-
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
-
10.1038/6368 10195220
-
Van Praag H Kempermann G Gage FH Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus Nature Neurosci 1999 2:266-267 10.1038/6368 10195220
-
(1999)
Nature Neurosci
, vol.2
, pp. 266-267
-
-
Van Praag, H.1
Kempermann, G.2
Gage, F.H.3
-
46
-
-
0035166388
-
Palliative care for people with late-stage Huntington's disease
-
10.1016/S0733-8619(05)70050-5 11854103
-
Moskowitz CB Marder K Palliative care for people with late-stage Huntington's disease Neurol Clin 2001 19:849-865 10.1016/ S0733-8619(05)70050-5 11854103
-
(2001)
Neurol Clin
, vol.19
, pp. 849-865
-
-
Moskowitz, C.B.1
Marder, K.2
-
48
-
-
12144288251
-
Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset
-
373491 10.1073/pnas.0308679101
-
Wexler NS Lorimer J Porter J Gomez F Moskowitz C Shackell E Marder K Penchaszadeh G Roberts SA Gayan J Brocklebank D Cherny SS Cardon LR Gray J Dlouhy SR Wiktorski S Hodes ME Conneally PM Penney JB Gusella J Cha JH Irizarry M Rosas D Hersch S Hollingsworth Z MacDonald M Young AB Andresen JM Housman DE De Young MM Bonilla E Stillings T Negrette A Snodgrass SR Martinez-Jaurrieta MD Ramos-Arroyo MA Bickham J Ramos JS Marshall F Shoulson I Rey GJ Feigin A Arnheim N Acevedo-Cruz A Acosta L Alvir J Fischbeck K Thompson LM Young A Dure L O'Brien CJ Paulsen J Brickman A Krch D Peery S Hogarth P Higgins DS Jr Landwehrmeyer B U.S.-Venezuela Collaborative Research Project Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset Proc Natl Acad Sci USA 2004 101:3498-3503 373491 14993615 10.1073/pnas.0308679101
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3498-3503
-
-
Wexler, N.S.1
Lorimer, J.2
Porter, J.3
Gomez, F.4
Moskowitz, C.5
Shackell, E.6
Marder, K.7
Penchaszadeh, G.8
Roberts, S.A.9
Gayan, J.10
Brocklebank, D.11
Cherny, S.S.12
Cardon, L.R.13
Gray, J.14
Dlouhy, S.R.15
Wiktorski, S.16
Hodes, M.E.17
Conneally, P.M.18
Penney, J.B.19
Gusella, J.20
Cha, J.H.21
Irizarry, M.22
Rosas, D.23
Hersch, S.24
Hollingsworth, Z.25
MacDonald, M.26
Young, A.B.27
Andresen, J.M.28
Housman, D.E.29
De Young, M.M.30
Bonilla, E.31
Stillings, T.32
Negrette, A.33
Snodgrass, S.R.34
Martinez-Jaurrieta, M.D.35
Ramos-Arroyo, M.A.36
Bickham, J.37
Ramos, J.S.38
Marshall, F.39
Shoulson, I.40
Rey, G.J.41
Feigin, A.42
Arnheim, N.43
Acevedo-Cruz, A.44
Acosta, L.45
Alvir, J.46
Fischbeck, K.47
Thompson, L.M.48
Young, A.49
Dure, L.50
O'Brien, C.J.51
Paulsen, J.52
Brickman, A.53
Krch, D.54
Peery, S.55
Hogarth, P.56
Higgins Jr., D.S.57
Landwehrmeyer, B.58
more..
-
49
-
-
0033457954
-
Differential clinical and motor control function in a pair of monozygotic twins with Huntington's disease
-
10.1002/1531-8257(199903)14:2<320::AID-MDS1018>3.0.CO;2-Z 10091627
-
Georgiou N Bradshaw JL Chiu E Tudor A O'Gorman L Phillips JG Differential clinical and motor control function in a pair of monozygotic twins with Huntington's disease Mov Disord 1999 14:320-325 10.1002/1531-8257(199903)14:2<320::AID-MDS1018>3.0.CO;2-Z 10091627
-
(1999)
Mov Disord
, vol.14
, pp. 320-325
-
-
Georgiou, N.1
Bradshaw, J.L.2
Chiu, E.3
Tudor, A.4
O'Gorman, L.5
Phillips, J.G.6
-
50
-
-
33644919176
-
Brain reserve and dementia: A systematic review
-
10.1017/S0033291705006264 16207391
-
Valenzuela MJ Sachdev P Brain reserve and dementia: A systematic review Psychol Med 2006 36:441-454 10.1017/S0033291705006264 16207391
-
(2006)
Psychol Med
, vol.36
, pp. 441-454
-
-
Valenzuela, M.J.1
Sachdev, P.2
-
51
-
-
4043147336
-
Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition
-
10.1097/01.wnr.0000137183.68847.4e 15257141
-
Arendash GW Garcia MF Costa DA Cracchiolo JR Wefes IM Potter H Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition Neuroreport 2004 15:1751-1754 10.1097/01.wnr.0000137183.68847.4e 15257141
-
(2004)
Neuroreport
, vol.15
, pp. 1751-1754
-
-
Arendash, G.W.1
Garcia, M.F.2
Costa, D.A.3
Cracchiolo, J.R.4
Wefes, I.M.5
Potter, H.6
-
52
-
-
18244384051
-
Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease
-
10.1523/JNEUROSCI.0496-05.2005 15858047
-
Adlard PA Perreau VM Pop V Cotman CW Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease J Neurosci 2005 25:4217-4221 10.1523/JNEUROSCI.0496-05.2005 15858047
-
(2005)
J Neurosci
, vol.25
, pp. 4217-4221
-
-
Adlard, P.A.1
Perreau, V.M.2
Pop, V.3
Cotman, C.W.4
-
53
-
-
21144456098
-
Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease
-
10.1523/JNEUROSCI.5080-04.2005 15917461
-
Jankowsky JL Melnikova T Fadale DJ Xu GM Slunt HH Gonzales V Younkin LH Younkin SG Borchelt DR Savonenko AV Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease J Neurosci 2005 25:5217-5224 10.1523/JNEUROSCI.5080-04.2005 15917461
-
(2005)
J Neurosci
, vol.25
, pp. 5217-5224
-
-
Jankowsky, J.L.1
Melnikova, T.2
Fadale, D.J.3
Xu, G.M.4
Slunt, H.H.5
Gonzales, V.6
Younkin, L.H.7
Younkin, S.G.8
Borchelt, D.R.9
Savonenko, A.V.10
-
54
-
-
20044377403
-
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice
-
10.1016/j.cell.2005.01.015 15766532
-
Lazarov O Robinson J Tang YP Hairston IS Korade-Mirnics Z Lee VM Hersh LB Sapolsky RM Mirnics K Sisodia SS Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice Cell 2005 120:701-713 10.1016/j.cell.2005.01.015 15766532
-
(2005)
Cell
, vol.120
, pp. 701-713
-
-
Lazarov, O.1
Robinson, J.2
Tang, Y.P.3
Hairston, I.S.4
Korade-Mirnics, Z.5
Lee, V.M.6
Hersh, L.B.7
Sapolsky, R.M.8
Mirnics, K.9
Sisodia, S.S.10
-
55
-
-
0346749428
-
Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: Involvement of dopamine transporter and trophic factors
-
14657156
-
Bezard E Dovero S Belin D Duconger S Jackson-Lewis V Przedborski S Piazza PV Gross CE Jaber M Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: Involvement of dopamine transporter and trophic factors J Neurosci 2003 23:10999-11007 14657156
-
(2003)
J Neurosci
, vol.23
, pp. 10999-11007
-
-
Bezard, E.1
Dovero, S.2
Belin, D.3
Duconger, S.4
Jackson-Lewis, V.5
Przedborski, S.6
Piazza, P.V.7
Gross, C.E.8
Jaber, M.9
-
56
-
-
34249667112
-
Environmental enrichment in adulthood promotes amblyopia recovery through a reduction of intracortical inhibition
-
10.1038/nn1899 17468749
-
Sale A Maya Vetencourt JF Medini P Cenni MC Baroncelli L De Pasquale R Maffei L Environmental enrichment in adulthood promotes amblyopia recovery through a reduction of intracortical inhibition Nat Neurosci 2007 10:679-681 10.1038/nn1899 17468749
-
(2007)
Nat Neurosci
, vol.10
, pp. 679-681
-
-
Sale, A.1
Maya Vetencourt, J.F.2
Medini, P.3
Cenni, M.C.4
Baroncelli, L.5
De Pasquale, R.6
Maffei, L.7
-
57
-
-
0037398420
-
Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases
-
12667098
-
Steffan JS Thompson LM Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases Expert Opin Ther Targets 2003 7:201-13 12667098
-
(2003)
Expert Opin Ther Targets
, vol.7
, pp. 201-213
-
-
Steffan, J.S.1
Thompson, L.M.2
-
58
-
-
23644460882
-
Novel therapeutic targets for Huntington's disease
-
10.1517/14728222.9.4.639 16083335
-
Hannan AJ Novel therapeutic targets for Huntington's disease Expert Opin Ther Targets 2005 9:639-650 10.1517/14728222.9.4.639 16083335
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 639-650
-
-
Hannan, A.J.1
-
59
-
-
0034745927
-
PLC-β1, activated via mGluRs, mediates activity-dependent differentiation in cerebral cortex
-
10.1038/85132 11224545
-
Hannan AJ Blakemore C Katsnelson A Vitalis T Huber KM Bear M PLC-β1, activated via mGluRs, mediates activity-dependent differentiation in cerebral cortex Nature Neurosci 2001 4:282-288 10.1038/85132 11224545
-
(2001)
Nature Neurosci
, vol.4
, pp. 282-288
-
-
Hannan, A.J.1
Blakemore, C.2
Katsnelson, A.3
Vitalis, T.4
Huber, K.M.5
Bear, M.6
|