A controlled trial of fluoxetine in nondepressed patients with Huntington's disease

Movement Disorders

Volumn 12, Issue 3, 1997, Pages 397-401

  Como, Peter G ^a,c   Rubin, Allen J ^b   O'Brien, Chris F ^a   Lawler, Kathy ^b   Hickey, Charlyne ^a   Rubin, Ann E ^b   Henderson, Robin ^a   McDermott, Michael P ^a   McDermott, Maria ^a   Steinberg, Kim ^a   Shoulson, Ira ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Depression; Fluoxetine; Functional capacity; Huntington's disease

Indexed keywords

FLUOXETINE; PLACEBO;

ADULT; AGED; AGITATION; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; HUMAN; HUNTINGTON CHOREA; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANTIDEPRESSIVE AGENTS; COGNITION; DEPRESSIVE DISORDER; DOUBLE-BLIND METHOD; FEMALE; FLUOXETINE; HUMANS; HUNTINGTON DISEASE; MALE; MIDDLE AGED; PLACEBOS;

EID: 16744362352     PISSN: 08853185     EISSN: None     Source Type: Journal    
DOI: 10.1002/mds.870120319     Document Type: Article

References (26)

1. Shoulson I. Huntington's disease. In: Asbury AK, McKhann GM, McDonald, eds. Diseases of the nervous system, 2nd ed. Philadelphia: WB Saunders, 1992:1159-1168.
2. Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1992; 72:971-983.
3. Caine ED, Shoulson I. Psychiatric syndromes in Huntington's disease. Am J Psychiatry 1983;140:728-733.
4. Holstein SE, Folstein MF. Psychiatric features of Huntington's disease: recent approaches and findings. Psychiatric Dev 1983;1:193-205.
5. Shoulson I, Fahn S. Huntington's disease: clinical care and evaluation. Neurology 1979;29:1-3.
6. Shoulson I. Huntington's disease: functional capacities in patients treated with neuroleptic and antidepressant drugs. Neurology 1981;31:1333-1335.
7. Shoulson I, Kurlan R, Rubin AJ et al. Assessment of functional capacity in neurodegenerative movements disorders: Huntington's disease as a prototype. In: Munsat, TL, ed. Quantification of neurologic deficit. Boston: Butterworths, 1989:271-283.
8. Young AB, Shoulson I, Penney JB, et al. Huntington's disease in Venezuela: neurological features and functional decline. Neurology 1986;36:244-249.
9. Shoulson I, Odoroff C, Oakes D, et al. A controlled clinical trial of baclofen as protective therapy in early Huntington's disease. Ann Neural 1989;25:252-259.
10. Gram LF. Fluoxetine. N Engl J Med 1994;331:1354-1361.
11. Hamilton M. Development of a rating scale for primary depressive illness. Br J Psychosoc Clin Psychol 1967;6:278-296.
12. Folstein MF, Folstein SE, McHugh PR. Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975:2:189-198.
13. Buschke H. Selective reminding for the analysis of memory and learning. J Verbal Learning Verbal Behav 1973;12: 543-550.
14. Bamford K, Caine E, Kido D, et al. Neuropsychological impairment in early Huntington's disease: functional and CT correlates. Neurology 1986;36(suppl 1):102-103.
15. Spreen O, Benton AL. Neurosensory center comprehensive examination for aphasia (NCCEA)-revised edition. Victoria: University of Victoria, Neuropsychology Laboratory, 1977.
16. Ruff P. Ruff figurai fluency test: administration manual. San Diego: Neuropsychological Resources, 1988.
17. Reitan R and Wolfson D. The Halstead-Reitan neuropsychological test battery. Tucson: Neuropsychology Press, 1985.
18. Stroop JR. Studies of interference in serial verbal reaction. J Exp Psychol 1935;18:643-662.
19. Wechsler D. Wechsler adult intelligence scale-revised. New York: Psychological Corporation, 1981.
20. Zung WW. A rating instrument for anxiety. Psychosomatics 1971;12:371-379.
21. Cooper J. The Leyton obsessional inventory. Psychol Med 1970;l:48-64.
22. Derogotis L. SCL-90R manual-II. Towson, MD: Clinical Psychometric Research, 1983.
23. Williams JM. Cognitive behavior rating scales: research edition. Odessa, Florida: Psychological Assessment Resources, Inc., 1990.
24. Conover WJ. Practical nonparametric statistics, 2nd ed. New York: Wiley, 1980.
25. McDougal CJ, Goodman WK, Price LH. The pharmacotherapy of obsessive-compulsive disorder. Pharmacopsychiatry 1993;26:24-29.
26. Holstein SE. Huntington's disease: a disorder of families. Baltimore: Johns Hopkins University Press, 1989;49-64.