Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease

Journal of Clinical Investigation

Volumn 117, Issue 10, 2007, Pages 2889-2902

  Cho, Sung Rae ^a,e   Benraiss, Abdellatif ^a,b   Chmielnicki, Eva ^b   Samdani, Amer ^b,c,f   Economides, Aris ^d   Goldman, Steven A ^a,b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

^d REGENERON PHARMACEUTICALS INC   (United States)

^e Yonsei University College of Medicine   (South Korea)

^f CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; BROXURIDINE; CYTARABINE; DOUBLECORTIN; ENKEPHALIN; HUNTINGTIN; NOGGIN; PHOSPHOPROTEIN DARPP 32; PROTEIN P27; SUBSTANCE P; TUBULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG INHIBITION; GLOBUS PALLIDUS; HUNTINGTON CHOREA; MOTOR PERFORMANCE; MOUSE; NEOSTRIATUM; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ROTAROD TEST;

ADENOVIRIDAE; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENKEPHALINS; GLOBUS PALLIDUS; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; MITOSIS; NEOSTRIATUM; NEURONS; REGENERATION; SUBSTANCE P; TUBULIN;

EID: 34948855498     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI31778     Document Type: Article

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