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Volumn 23, Issue 1, 1999, Pages 181-192

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DNA FRAGMENT;

EID: 0033136692     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80764-3     Document Type: Article
Times cited : (735)

References (46)
  • 1
    • 0026609559 scopus 로고
    • Alternative excitotoxic hypothesis
    • Albin, R.L., and Greenamyre, J.T. (1992). Alternative excitotoxic hypothesis. Neurology 42, 733-738.
    • (1992) Neurology , vol.42 , pp. 733-738
    • Albin, R.L.1    Greenamyre, J.T.2
  • 2
    • 0024533140 scopus 로고
    • Differential sparing of somatostain-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions
    • Beal, M.F., Lowall, N.W., Swartz, K.J., Ferrante, R.J., and Martin, J.B. (1989). Differential sparing of somatostain-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions. Synapse 3, 38-47.
    • (1989) Synapse , vol.3 , pp. 38-47
    • Beal, M.F.1    Lowall, N.W.2    Swartz, K.J.3    Ferrante, R.J.4    Martin, J.B.5
  • 3
    • 0030610409 scopus 로고    scopus 로고
    • Dentatorubral and pallidoluysian atrophy (DRPLA)
    • Clinical and neuropathological findings in genetically confirmed North American and European pedigrees.
    • Becher, M.W., Rubinsztein, D.C., Leggo, J., Wagster, M.V., Stine, O.C., Ranen, N.G., Franz, M.L., Abbott, M.H., Sherr, M., Macmillan, et al. (1997). Dentatorubral and pallidoluysian atrophy (DRPLA). Clinical and neuropathological findings in genetically confirmed North American and European pedigrees. Mov. Disord. 12, 519-530.
    • (1997) Mov. Disord. , vol.12 , pp. 519-530
    • Becher, M.W.1    Rubinsztein, D.C.2    Leggo, J.3    Wagster, M.V.4    Stine, O.C.5    Ranen, N.G.6    Franz, M.L.7    Abbott, M.H.8    Sherr, M.9
  • 4
    • 0031721511 scopus 로고    scopus 로고
    • Calsenilin: A calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment
    • Buxbaum, J.D., Choi, E.K., Luo, Y., Lilliehook, C., Crowley, A.C., Merriam, D.E., and Wasco, W. (1998). Calsenilin: A calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment. Nat. Med. 4, 1177-1181.
    • (1998) Nat. Med. , vol.4 , pp. 1177-1181
    • Buxbaum, J.D.1    Choi, E.K.2    Luo, Y.3    Lilliehook, C.4    Crowley, A.C.5    Merriam, D.E.6    Wasco, W.7
  • 8
    • 0013571921 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative diseases
    • Coyle, J.T., and Puttfarchen, P. (1993). Oxidative stress, glutamate, and neurodegenerative diseases. Ann. Neurol. 38, 357-366.
    • (1993) Ann. Neurol. , vol.38 , pp. 357-366
    • Coyle, J.T.1    Puttfarchen, P.2
  • 11
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • Difiglia, M., Sapp, E., Chase, K.O., Davies, S.W., Bates, G.P., Vonsattel, J.P., and Aronin, N. (1997). Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277, 1990-1993.
    • (1997) Science , vol.277 , pp. 1990-1993
    • Difiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6    Aronin, N.7
  • 13
    • 0028150583 scopus 로고
    • Insertion of a pathogenic mutation into a yeast artificial chromosome containing the human amyloid precursor protein gene
    • Duff, K., McGuigan, A., Huxley, C., Schulz, F., and Hardy, J. (1994). Insertion of a pathogenic mutation into a yeast artificial chromosome containing the human amyloid precursor protein gene. Gene Ther. 1, 70-75.
    • (1994) Gene Ther. , vol.1 , pp. 70-75
    • Duff, K.1    McGuigan, A.2    Huxley, C.3    Schulz, F.4    Hardy, J.5
  • 21
    • 0032946228 scopus 로고    scopus 로고
    • In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in huntington disease
    • Hackam, A.S., Singaraja, R., Zhang, T., Can, L., and Hayden, M.R. (1999). In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in huntington disease. Hum. Mol. Genet. 8, 25-33.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 25-33
    • Hackam, A.S.1    Singaraja, R.2    Zhang, T.3    Can, L.4    Hayden, M.R.5
  • 25
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group
    • Huntington's Disease Collaborative Research Group (1993). A novel gene containing a trinucleotide repeat that is expanded and unstable on huntington's disease chromosomes. Cell 72, 971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 27
    • 0032191848 scopus 로고    scopus 로고
    • Neuronal intranuclear inclusions in polyglutamine diseases: Nuclear weapons or nuclear fallout?
    • Kim, T.-W., and Tanzi, R.E. (1998). Neuronal intranuclear inclusions in polyglutamine diseases: Nuclear weapons or nuclear fallout? NeuRon 21, 657-659.
    • (1998) NeuRon , vol.21 , pp. 657-659
    • Kim, T.-W.1    Tanzi, R.E.2
  • 28
    • 0032475941 scopus 로고    scopus 로고
    • Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
    • Klement, I.A., Skinner, P.J., Kaytor, M.D., Yi, H., Hersch, S.M., Clark, H.B., Zoghbi, H.Y., and Orr, H.T. (1998). Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice. Cell 95, 41-53.
    • (1998) Cell , vol.95 , pp. 41-53
    • Klement, I.A.1    Skinner, P.J.2    Kaytor, M.D.3    Yi, H.4    Hersch, S.M.5    Clark, H.B.6    Zoghbi, H.Y.7    Orr, H.T.8
  • 30
    • 0024280879 scopus 로고
    • Postsynaptic calcium is sufficient for potentiation of hippocampal synaptic transmission
    • Malenka, R.C., Kauer, J.A., Zucker, R.S., and Nicoll, R.A. (1988). Postsynaptic calcium is sufficient for potentiation of hippocampal synaptic transmission. Science 242, 81-84.
    • (1988) Science , vol.242 , pp. 81-84
    • Malenka, R.C.1    Kauer, J.A.2    Zucker, R.S.3    Nicoll, R.A.4
  • 31
    • 0026719832 scopus 로고
    • Temporal limits on the rise in postsynpatic calcium required for the induction of long-term potentiation
    • Malenka, R.C., Lancaster, B., and Zucker, R.S. (1992). Temporal limits on the rise in postsynpatic calcium required for the induction of long-term potentiation. Neuron 9, 121-128.
    • (1992) Neuron , vol.9 , pp. 121-128
    • Malenka, R.C.1    Lancaster, B.2    Zucker, R.S.3
  • 34
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an n-methyl-d-aspartate receptor antagonist, AP5
    • Morris, R.G., Anderson, E., Lynch, G.S., and Baudry, M. (1986). Selective impairment of learning and blockade of long-term potentiation by an n-methyl-d-aspartate receptor antagonist, AP5. Nature 19, 774-776.
    • (1986) Nature , vol.19 , pp. 774-776
    • Morris, R.G.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 35
    • 0029055717 scopus 로고
    • Targeted disruption of the huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
    • Nasir, J., Floresco, S.B., O'Kusky, J.R., Diewert, V.M., Richman, J.M., Zeisler, J., Borowski, A., Marth, J.D., Phillips, A.G., and Hayden, M.R. (1995). Targeted disruption of the huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Cell 81, 811-823.
    • (1995) Cell , vol.81 , pp. 811-823
    • Nasir, J.1    Floresco, S.B.2    O'Kusky, J.R.3    Diewert, V.M.4    Richman, J.M.5    Zeisler, J.6    Borowski, A.7    Marth, J.D.8    Phillips, A.G.9    Hayden, M.R.10
  • 38
    • 0032475931 scopus 로고    scopus 로고
    • Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
    • Saudou, F., Finkbeiner, S., Devys, D., and Greenberg, M.E. (1998). Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 95, 55-66.
    • (1998) Cell , vol.95 , pp. 55-66
    • Saudou, F.1    Finkbeiner, S.2    Devys, D.3    Greenberg, M.E.4
  • 41
    • 0027276977 scopus 로고
    • Neuronal loss in the hippocampus in huntington's disease: A comparison with HIV infection
    • Spargo, E., Everall, I.P., and Lantos, P.L. (1993). Neuronal loss in the hippocampus in huntington's disease: A comparison with HIV infection. J. Neurol. Neurosurg. Psychiatry 56, 487-491.
    • (1993) J. Neurol. Neurosurg. Psychiatry , vol.56 , pp. 487-491
    • Spargo, E.1    Everall, I.P.2    Lantos, P.L.3
  • 46
    • 84993912315 scopus 로고
    • Increased apoptosis and early embryonic lethality in mice nullizygous for the huntington's disease gene homologue
    • Zeitlin, S., Liu, J.-P., Chapman, D.L., Papaioannou, V.E., and Efstratiadis, A. (1995). Increased apoptosis and early embryonic lethality in mice nullizygous for the huntington's disease gene homologue. Nat. Genet. 11, 155-162.
    • (1995) Nat. Genet. , vol.11 , pp. 155-162
    • Zeitlin, S.1    Liu, J.-P.2    Chapman, D.L.3    Papaioannou, V.E.4    Efstratiadis, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.