-
2
-
-
70349437416
-
Kinesin superfamily motor proteins and intracellular transport
-
Hirokawa, N., Noda, Y., Tanaka, Y. & Niwa, S. Kinesin superfamily motor proteins and intracellular transport. Nature Rev. Mol. Cell Biol. 10, 682-696 (2009).
-
(2009)
Nature Rev. Mol. Cell Biol.
, vol.10
, pp. 682-696
-
-
Hirokawa, N.1
Noda, Y.2
Tanaka, Y.3
Niwa, S.4
-
3
-
-
70450228589
-
Regulators of the cytoplasmic dynein motor
-
Kardon, J. R. & Vale, R. D. Regulators of the cytoplasmic dynein motor. Nature Rev. Mol. Cell Biol. 10, 854-865 (2009).
-
(2009)
Nature Rev. Mol. Cell Biol.
, vol.10
, pp. 854-865
-
-
Kardon, J.R.1
Vale, R.D.2
-
4
-
-
75149128079
-
Myosin VI: An innovative motor that challenged the swinging lever arm hypothesis
-
Spudich, J. A. & Sivaramakrishnan, S. Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis. Nature Rev. Mol. Cell Biol. 11, 128-137 (2010).
-
(2010)
Nature Rev. Mol. Cell Biol.
, vol.11
, pp. 128-137
-
-
Spudich, J.A.1
Sivaramakrishnan, S.2
-
5
-
-
70350446761
-
Traffic control: Regulation of kinesin motors
-
Verhey, K. J. & Hammond, J. W. Traffic control: regulation of kinesin motors. Nature Rev. Mol. Cell Biol. 10, 765-777 (2009).
-
(2009)
Nature Rev. Mol. Cell Biol.
, vol.10
, pp. 765-777
-
-
Verhey, K.J.1
Hammond, J.W.2
-
6
-
-
70350454867
-
Non-muscle myosin II takes centre stage in cell adhesion and migration
-
Vicente-Manzanares, M., Ma, X. F., Adelstein, R. S. & Horwitz, A. R. Non-muscle myosin II takes centre stage in cell adhesion and migration. Nature Rev. Mol. Cell Biol. 10, 778-790 (2009).
-
(2009)
Nature Rev. Mol. Cell Biol.
, vol.10
, pp. 778-790
-
-
Vicente-Manzanares, M.1
Ma, X.F.2
Adelstein, R.S.3
Horwitz, A.R.4
-
7
-
-
0036150882
-
Kinesin: Switch I & II and the motor mechanism
-
Kull, F. J. & Endow, S. A. Kinesin: switch I & II and the motor mechanism. J. Cell Sci. 115, 15-23 (2002).
-
(2002)
J. Cell Sci.
, vol.115
, pp. 15-23
-
-
Kull, F.J.1
Endow, S.A.2
-
8
-
-
26844566272
-
-
Fibrous Proteins: Muscle and Molecular Motors, Elsevier Academic Press Inc., San Diego
-
Geeves, M. A. & Holmes, K. C. in Advances in Protein Chemistry Vol. 71 (Fibrous Proteins: Muscle and Molecular Motors) 161-193 (Elsevier Academic Press Inc., San Diego, 2005).
-
(2005)
Advances in Protein Chemistry
, vol.71
, pp. 161-193
-
-
Geeves, M.A.1
Holmes, K.C.2
-
9
-
-
39949083937
-
The role of microtubules in processive kinesin movement
-
Kikkawa, M. The role of microtubules in processive kinesin movement. Trends Cell Biol. 18, 128-135 (2008).
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 128-135
-
-
Kikkawa, M.1
-
10
-
-
0033576727
-
A structural change in the kinesin motor protein that drives motility
-
A classic study that provides evidence for the kinesin neck linker conformational change by using electron paramagnetic resonance, FRET, kinetics and electron microscopy
-
Rice, S. et al. A structural change in the kinesin motor protein that drives motility. Nature 402, 778-784 (1999). A classic study that provides evidence for the kinesin neck linker conformational change by using electron paramagnetic resonance, FRET, kinetics and electron microscopy.
-
(1999)
Nature
, vol.402
, pp. 778-784
-
-
Rice, S.1
-
11
-
-
0027194702
-
Three-dimensional structure of myosin subfragment-1: A molecular motor
-
Presented the first X-ray crystallography structure of a myosin motor domain, which strongly advanced our understanding of motor function
-
Rayment, I. et al. Three-dimensional structure of myosin subfragment-1: a molecular motor. Science 261, 50-58 (1993). Presented the first X-ray crystallography structure of a myosin motor domain, which strongly advanced our understanding of motor function.
-
(1993)
Science
, vol.261
, pp. 50-58
-
-
Rayment, I.1
-
12
-
-
0027220271
-
Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1
-
Schröder, R. R. et al. Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1. Nature 364, 171-174 (1993).
-
(1993)
Nature
, vol.364
, pp. 171-174
-
-
Schröder, R.R.1
-
13
-
-
0032483563
-
Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: Visualization of the pre-power stroke state
-
Dominguez, R., Freyzon, Y., Trybus, K. M. & Cohen, C. Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell 94, 559-571 (1998).
-
(1998)
Cell
, vol.94
, pp. 559-571
-
-
Dominguez, R.1
Freyzon, Y.2
Trybus, K.M.3
Cohen, C.4
-
14
-
-
1642340974
-
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: A novel conformation of the myosin head
-
Houdusse, A., Kalbokis, V. N., Himmel, D., Szent-Gyorgyi, A. G. & Cohen, C. Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell 97, 459-470 (1999).
-
(1999)
Cell
, vol.97
, pp. 459-470
-
-
Houdusse, A.1
Kalbokis, V.N.2
Himmel, D.3
Szent-Gyorgyi, A.G.4
Cohen, C.5
-
15
-
-
0037164812
-
The prepower stroke conformation of myosin V
-
Burgess, S. et al. The prepower stroke conformation of myosin V. J. Cell Biol. 159, 983-991 (2002).
-
(2002)
J. Cell Biol.
, vol.159
, pp. 983-991
-
-
Burgess, S.1
-
16
-
-
0034660532
-
Two-headed binding of a processive myosin to F-actin
-
Walker, M. L. et al. Two-headed binding of a processive myosin to F-actin. Nature 405, 804-807 (2000).
-
(2000)
Nature
, vol.405
, pp. 804-807
-
-
Walker, M.L.1
-
17
-
-
77952934976
-
Structural and functional insights into the myosin motor mechanism
-
Sweeney, H. L. & Houdusse, A. Structural and functional insights into the myosin motor mechanism. Annu. Rev. Biophys. 39, 539-57 (2010).
-
(2010)
Annu. Rev. Biophys.
, vol.39
, pp. 539-557
-
-
Sweeney, H.L.1
Houdusse, A.2
-
18
-
-
0028261701
-
Single myosin molecule mechanics-piconewton forces and nanometer steps
-
Describes the three-bead single-molecule assay for myosin for the first time and is also the first report of myosin power strokes and single-molecule forces
-
Finer, J. T., Simmons, R. M. & Spudich, J. A. Single myosin molecule mechanics-piconewton forces and nanometer steps. Nature 368, 113-119 (1994). Describes the three-bead single-molecule assay for myosin for the first time and is also the first report of myosin power strokes and single-molecule forces.
-
(1994)
Nature
, vol.368
, pp. 113-119
-
-
Finer, J.T.1
Simmons, R.M.2
Spudich, J.A.3
-
19
-
-
61849174756
-
-
Biothermodynamics Part A, Eds Johnson, M. L., Holt, J. M. & Ackers, G. K Elsevier Academic Press Inc., San Diego
-
De La Cruz, E. M. & Ostap, E. M. in Methods in Enzymology Vol. 455, (Biothermodynamics Part A) (Eds Johnson, M. L., Holt, J. M. & Ackers, G. K) 157-192 (Elsevier Academic Press Inc., San Diego, 2009).
-
(2009)
Methods in Enzymology
, vol.455
, pp. 157-192
-
-
De La Cruz, E.M.1
Ostap, E.M.2
-
20
-
-
13444292382
-
Dynamics of actomyosin interactions in relation to the cross-bridge cycle
-
Zeng, W. et al. Dynamics of actomyosin interactions in relation to the cross-bridge cycle. Phil. Trans. R. Soc. B 359, 1843-1855 (2004).
-
(2004)
Phil. Trans. R. Soc. B
, vol.359
, pp. 1843-1855
-
-
Zeng, W.1
-
21
-
-
26844579689
-
-
Fibrous Proteins: Muscle and Molecular Motors, Elsevier Academic Press Inc., San Diego
-
Marx, A., Muller, J. & Mandelkow, E. in Advances in Protein Chemistry Vol. 71 (Fibrous Proteins: Muscle and Molecular Motors) 299-344 (Elsevier Academic Press Inc., San Diego, 2005).
-
(2005)
Advances in Protein Chemistry
, vol.71
, pp. 299-344
-
-
Marx, A.1
Muller, J.2
Mandelkow, E.3
-
23
-
-
24644445512
-
Structure of the light chain-binding domain of myosin V
-
Terrak, M., Rebowski, G., Lu, R. C., Grabarek, Z. & Dominguez, R. Structure of the light chain-binding domain of myosin V. Proc. Natl Acad. Sci. USA 102, 12718-12723 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 12718-12723
-
-
Terrak, M.1
Rebowski, G.2
Lu, R.C.3
Grabarek, Z.4
Dominguez, R.5
-
24
-
-
33645531531
-
Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor
-
Bosch, J. et al. Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor. Proc. Natl Acad. Sci. USA 103, 4852-4857 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 4852-4857
-
-
Bosch, J.1
-
25
-
-
66349123278
-
Structure of the complex of a mitotic kinesin with its calcium binding regulator
-
Vinogradova, M. V., Malanina, G. G., Reddy, A. S. N. & Fletterick, R. J. Structure of the complex of a mitotic kinesin with its calcium binding regulator. Proc. Natl Acad. Sci. USA 106, 8175-8179 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 8175-8179
-
-
Vinogradova, M.V.1
Malanina, G.G.2
Reddy, A.S.N.3
Fletterick, R.J.4
-
26
-
-
0036774026
-
Microtubule structure at 8 Å Resolution
-
Li, H. L., DeRosier, D. J., Nicholson, W. V., Nogales, E. & Downing, K. H. Microtubule structure at 8 Å Resolution. Structure 10, 1317-1328 (2002).
-
(2002)
Structure
, vol.10
, pp. 1317-1328
-
-
Li, H.L.1
DeRosier, D.J.2
Nicholson, W.V.3
Nogales, E.4
Downing, K.H.5
-
27
-
-
0025052483
-
Molecular structure of F-actin and location of surface binding sites
-
Milligan, R. A., Whittaker, M. & Safer, D. Molecular structure of F-actin and location of surface binding sites. Nature 348, 217-221 (1990).
-
(1990)
Nature
, vol.348
, pp. 217-221
-
-
Milligan, R.A.1
Whittaker, M.2
Safer, D.3
-
28
-
-
0027226230
-
Structure of the actin-myosin complex and its implications for muscle-contraction
-
Rayment, I. et al. Structure of the actin-myosin complex and its implications for muscle-contraction. Science 261, 58-65 (1993).
-
(1993)
Science
, vol.261
, pp. 58-65
-
-
Rayment, I.1
-
29
-
-
0025868445
-
Microtubule dynamics and microtubule caps: A time-resolved cryo-electron microscopy study
-
Mandelkow, E. M., Mandelkow, E. & Milligan, R. A. Microtubule dynamics and microtubule caps: a time-resolved cryo-electron microscopy study. J. Cell Biol. 114, 977-991 (1991).
-
(1991)
J. Cell Biol.
, vol.114
, pp. 977-991
-
-
Mandelkow, E.M.1
Mandelkow, E.2
Milligan, R.A.3
-
30
-
-
0029795642
-
Three-dimensional cryoelectron microscopy of dimeric kinesin and ncd motor domains on microtubules
-
Hirose, K., Lockhart, A., Cross, R. A. & Amos, L. A. Three-dimensional cryoelectron microscopy of dimeric kinesin and ncd motor domains on microtubules. Proc. Natl Acad. Sci. USA 93, 9539-9544 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 9539-9544
-
-
Hirose, K.1
Lockhart, A.2
Cross, R.A.3
Amos, L.A.4
-
31
-
-
0037434697
-
Dynein structure and power stroke
-
Burgess, S. A., Walker, M. L., Sakakibara, H., Knight, P. J. & Oiwa, K. Dynein structure and power stroke. Nature 421, 715-718 (2003).
-
(2003)
Nature
, vol.421
, pp. 715-718
-
-
Burgess, S.A.1
Walker, M.L.2
Sakakibara, H.3
Knight, P.J.4
Oiwa, K.5
-
32
-
-
64049086564
-
9-Ångström structure of a microtubule-bound mitotic motor
-
Bodey, A. J., Kikkawa, M. & Moores, C. A. 9-Ångström structure of a microtubule-bound mitotic motor. J. Mol. Biol. 388, 218-224 (2009).
-
(2009)
J. Mol. Biol.
, vol.388
, pp. 218-224
-
-
Bodey, A.J.1
Kikkawa, M.2
Moores, C.A.3
-
33
-
-
33746152398
-
The cargo-binding domain regulates structure and activity of myosin 5
-
Thirumurugan, K., Sakamoto, T., Hammer, J. A., Sellers, J. R. & Knight, P. J. The cargo-binding domain regulates structure and activity of myosin 5. Nature 442, 212-215 (2006).
-
(2006)
Nature
, vol.442
, pp. 212-215
-
-
Thirumurugan, K.1
Sakamoto, T.2
Hammer, J.A.3
Sellers, J.R.4
Knight, P.J.5
-
34
-
-
33746129173
-
Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography
-
Liu, J., Taylor, D. W., Krementsova, E. B., Trybus, K. M. & Taylor, K. A. Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography. Nature 442, 208-211 (2006).
-
(2006)
Nature
, vol.442
, pp. 208-211
-
-
Liu, J.1
Taylor, D.W.2
Krementsova, E.B.3
Trybus, K.M.4
Taylor, K.A.5
-
35
-
-
0344198646
-
Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition
-
Al-Bassam, J. et al. Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition. J. Cell Biol. 163, 743-753 (2003).
-
(2003)
J. Cell Biol.
, vol.163
, pp. 743-753
-
-
Al-Bassam, J.1
-
36
-
-
0033591331
-
Formation of the compact confomer of kinesin requires a COOH-terminal heavy chain domain and inhibits microtubule-stimulated ATPase activity
-
Stock, M. F. et al. Formation of the compact confomer of kinesin requires a COOH-terminal heavy chain domain and inhibits microtubule-stimulated ATPase activity. J. Biol. Chem. 274, 14617-14623 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14617-14623
-
-
Stock, M.F.1
-
37
-
-
48249153389
-
The Kinesin-1 motor protein is regulated by a direct interaction of its head and tail
-
Dietrich, K. A. et al. The Kinesin-1 motor protein is regulated by a direct interaction of its head and tail. Proc. Natl Acad. Sci. USA 105, 8938-8943 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 8938-8943
-
-
Dietrich, K.A.1
-
38
-
-
14844330221
-
Structural studies by electron tomography: From cells to molecules
-
Lucic, V., Forster, F. & Baumeister, W. Structural studies by electron tomography: from cells to molecules. Annu. Rev. Biochem. 74, 833-865 (2005).
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 833-865
-
-
Lucic, V.1
Forster, F.2
Baumeister, W.3
-
39
-
-
0020586332
-
Movement of myosincoated fluorescent beads on actin cables in vitro
-
Sheetz, M. P. & Spudich, J. A. Movement of myosincoated fluorescent beads on actin cables in vitro. Nature 303, 31-35 (1983).
-
(1983)
Nature
, vol.303
, pp. 31-35
-
-
Sheetz, M.P.1
Spudich, J.A.2
-
40
-
-
0023919181
-
Force measurements by micromanipulation of a single actin filament by glass needles
-
Kishino, A. & Yanagida, T. Force measurements by micromanipulation of a single actin filament by glass needles. Nature 334, 74-76 (1988).
-
(1988)
Nature
, vol.334
, pp. 74-76
-
-
Kishino, A.1
Yanagida, T.2
-
41
-
-
0021261156
-
Direct observation of motion of single F-actin filaments in the presence of myosin
-
Yanagida, T., Nakase, M., Nishiyama, K. & Oosawa, F. Direct observation of motion of single F-actin filaments in the presence of myosin. Nature 307, 58-60 (1984).
-
(1984)
Nature
, vol.307
, pp. 58-60
-
-
Yanagida, T.1
Nakase, M.2
Nishiyama, K.3
Oosawa, F.4
-
42
-
-
0001675681
-
Fluorescent actin-filaments move on myosin fixed to a glass surface
-
Kron, S. J. & Spudich, J. A. Fluorescent actin-filaments move on myosin fixed to a glass surface Proc. Natl Acad. Sci. USA 83, 6272-6276 (1986).
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 6272-6276
-
-
Kron, S.J.1
Spudich, J.A.2
-
43
-
-
0028803118
-
Movement and force produced by a single myosin head
-
A careful study of power strokes of single myosin dimers, which properly takes into account thermal fluctuations and gives the most accurate estimate of power-stroke amplitude
-
Molloy, J. E., Burns, J. E., Kendrick-Jones, J., Tregear, R. T. & White, D. C. S. Movement and force produced by a single myosin head. Nature 378, 209-212 (1995). A careful study of power strokes of single myosin dimers, which properly takes into account thermal fluctuations and gives the most accurate estimate of power-stroke amplitude.
-
(1995)
Nature
, vol.378
, pp. 209-212
-
-
Molloy, J.E.1
Burns, J.E.2
Kendrick-Jones, J.3
Tregear, R.T.4
White, D.C.S.5
-
44
-
-
18744364420
-
Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd
-
Wendt, T. G. et al. Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd. EMBO J. 21, 5969-5978 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 5969-5978
-
-
Wendt, T.G.1
-
45
-
-
0034306034
-
Working strokes by single molecules of the kinesin-related microtubule motor ncd
-
deCastro, M. J., Fondecave, R. M., Clarke, L. A., Schmidt, C. F. & Stewart, R. J. Working strokes by single molecules of the kinesin-related microtubule motor ncd. Nature Cell Biol. 2, 724-729 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 724-729
-
-
DeCastro, M.J.1
Fondecave, R.M.2
Clarke, L.A.3
Schmidt, C.F.4
Stewart, R.J.5
-
46
-
-
0034710696
-
A mutant of the motor protein kinesin that moves in both directions on microtubules
-
Endow, S. A. & Higuchi, H. A mutant of the motor protein kinesin that moves in both directions on microtubules. Nature 406, 913-916 (2000).
-
(2000)
Nature
, vol.406
, pp. 913-916
-
-
Endow, S.A.1
Higuchi, H.2
-
47
-
-
0027453868
-
Direct observation of kinesin stepping by optical trapping interferometry
-
The first report on the steps and stall forces of single kinesin motors, which were measured by optical trapping
-
Svoboda, K., Schmidt, C. F., Schnapp, B. J. & Block, S. M. Direct observation of kinesin stepping by optical trapping interferometry. Nature 365, 721-727 (1993). The first report on the steps and stall forces of single kinesin motors, which were measured by optical trapping.
-
(1993)
Nature
, vol.365
, pp. 721-727
-
-
Svoboda, K.1
Schmidt, C.F.2
Schnapp, B.J.3
Block, S.M.4
-
48
-
-
0033527043
-
Myosin-V is a processive actin-based motor
-
Mehta, A. D. et al. Myosin-V is a processive actin-based motor. Nature 400, 590-593 (1999).
-
(1999)
Nature
, vol.400
, pp. 590-593
-
-
Mehta, A.D.1
-
49
-
-
0034646431
-
Processive movement of single 22S dynein molecules occurs only at low ATP concentrations
-
Hirakawa, E., Higuchi, H. & Toyoshima, Y. Y. Processive movement of single 22S dynein molecules occurs only at low ATP concentrations. Proc. Natl Acad. Sci. USA 97, 2533-2537 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 2533-2537
-
-
Hirakawa, E.1
Higuchi, H.2
Toyoshima, Y.Y.3
-
50
-
-
33746253688
-
Single-molecule analysis of dynein processivity and stepping behavior
-
A landmark paper using quantum dots to perform single-molecule experiments with dimeric dynein, and showing processive stepping behaviour
-
Reck-Peterson, S. L. et al. Single-molecule analysis of dynein processivity and stepping behavior. Cell 126, 335-348 (2006). A landmark paper using quantum dots to perform single-molecule experiments with dimeric dynein, and showing processive stepping behaviour.
-
(2006)
Cell
, vol.126
, pp. 335-348
-
-
Reck-Peterson, S.L.1
-
51
-
-
33645803599
-
Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein
-
Toba, S., Watanabe, T. M., Yamaguchi-Okimoto, L., Toyoshima, Y. Y. & Higuchi, H. Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein. Proc. Natl Acad. Sci. USA 103, 5741-5745 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 5741-5745
-
-
Toba, S.1
Watanabe, T.M.2
Yamaguchi-Okimoto, L.3
Toyoshima, Y.Y.4
Higuchi, H.5
-
52
-
-
50649121477
-
Advances in single-molecule fluorescence methods for molecular biology
-
Joo, C., Balci, H., Ishitsuka, Y., Buranachai, C. & Ha, T. Advances in single-molecule fluorescence methods for molecular biology. Annu. Rev. Biochem. 77, 51-76 (2008).
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 51-76
-
-
Joo, C.1
Balci, H.2
Ishitsuka, Y.3
Buranachai, C.4
Ha, T.5
-
53
-
-
44449136151
-
Recent advances in optical tweezers
-
Moffitt, J. R., Chemla, Y. R., Smith, S. B. & Bustamante, C. Recent advances in optical tweezers. Annu. Rev. Biochem. 77, 205-228 (2008).
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 205-228
-
-
Moffitt, J.R.1
Chemla, Y.R.2
Smith, S.B.3
Bustamante, C.4
-
54
-
-
34347266453
-
High-resolution, single-molecule measurements of biomolecular motion
-
Greenleaf, W. J., Woodside, M. T. & Block, S. M. High-resolution, single-molecule measurements of biomolecular motion. Annu. Rev. Biophys. Biomol. Struct. 36, 171-190 (2007).
-
(2007)
Annu. Rev. Biophys. Biomol. Struct.
, vol.36
, pp. 171-190
-
-
Greenleaf, W.J.1
Woodside, M.T.2
Block, S.M.3
-
55
-
-
34247571461
-
Kinesin motor mechanics: Binding, stepping, tracking, gating, and limping
-
Block, S. M. Kinesin motor mechanics: binding, stepping, tracking, gating, and limping. Biophys. J. 92, 2986-2995 (2007).
-
(2007)
Biophys. J.
, vol.92
, pp. 2986-2995
-
-
Block, S.M.1
-
56
-
-
60749121148
-
Walking the walk: How kinesin and dynein coordinate their steps
-
Gennerich, A. & Vale, R. D. Walking the walk: how kinesin and dynein coordinate their steps. Curr. Opin. Cell Biol. 21, 59-67 (2009).
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 59-67
-
-
Gennerich, A.1
Vale, R.D.2
-
58
-
-
1542299042
-
The mechanism of myosin VI translocation an its load-induced anchoring
-
Altman, D., Sweeney, H. L. & Spudich, J. A. The mechanism of myosin VI translocation an its load-induced anchoring. Cell 116, 737-749 (2004).
-
(2004)
Cell
, vol.116
, pp. 737-749
-
-
Altman, D.1
Sweeney, H.L.2
Spudich, J.A.3
-
59
-
-
36249009069
-
Force-induced bidirectional stepping of cytoplasmic dynein
-
Showed, in a single-molecule assay, that the processive myosin V motor takes a step in two phases and, further, that it needs a thermal fluctuation to reach its next binding site
-
Gennerich, A., Carter, A. P., Reck-Peterson, S. L. & Vale, R. D. Force-induced bidirectional stepping of cytoplasmic dynein. Cell 131, 952-965 (2007). Showed, in a single-molecule assay, that the processive myosin V motor takes a step in two phases and, further, that it needs a thermal fluctuation to reach its next binding site.
-
(2007)
Cell
, vol.131
, pp. 952-965
-
-
Gennerich, A.1
Carter, A.P.2
Reck-Peterson, S.L.3
Vale, R.D.4
-
60
-
-
0028362896
-
Force and velocity measured for single kinesin molecules
-
Svoboda, K. & Block, S. M. Force and velocity measured for single kinesin molecules. Cell 77, 773-784 (1994).
-
(1994)
Cell
, vol.77
, pp. 773-784
-
-
Svoboda, K.1
Block, S.M.2
-
61
-
-
0036144267
-
The gated gait of the processive molecular motor, myosin V
-
Veigel, C., Wang, F., Bartoo, M. L., Sellers, J. R. & Molloy, J. E. The gated gait of the processive molecular motor, myosin V. Nature Cell Biol. 4, 59-65 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 59-65
-
-
Veigel, C.1
Wang, F.2
Bartoo, M.L.3
Sellers, J.R.4
Molloy, J.E.5
-
62
-
-
0030744142
-
Kinesin hydrolyses one ATP per 8-nm step
-
A landmark paper that proves, from the statistical analysis of single-molecule data, that kinesin uses one ATP molecule per 8 nm step
-
Schnitzer, M. J. & Block, S. M. Kinesin hydrolyses one ATP per 8-nm step. Nature 388, 386-390 (1997). A landmark paper that proves, from the statistical analysis of single-molecule data, that kinesin uses one ATP molecule per 8 nm step.
-
(1997)
Nature
, vol.388
, pp. 386-390
-
-
Schnitzer, M.J.1
Block, S.M.2
-
63
-
-
51349088578
-
Direct observation of the mechanochemical coupling in myosin Va during processive movement
-
Sakamoto, T., Webb, M. R., Forgacs, E., White, H. D. & Sellers, J. R. Direct observation of the mechanochemical coupling in myosin Va during processive movement. Nature 455, 128-132 (2008).
-
(2008)
Nature
, vol.455
, pp. 128-132
-
-
Sakamoto, T.1
Webb, M.R.2
Forgacs, E.3
White, H.D.4
Sellers, J.R.5
-
64
-
-
0033535556
-
The motor protein myosin-I produces its working stroke in two steps
-
Veigel, C. et al. The motor protein myosin-I produces its working stroke in two steps. Nature 398, 530-533 (1999).
-
(1999)
Nature
, vol.398
, pp. 530-533
-
-
Veigel, C.1
-
65
-
-
4344594882
-
Mechanochemical coupling of two substeps in a single myosin V motor
-
Uemura, S., Higuchi, H., Olivares, A. O., De La Cruz, E. M. & Ishiwata, S. Mechanochemical coupling of two substeps in a single myosin V motor. Nature Struct. Mol. Biol. 11, 877-883 (2004).
-
(2004)
Nature Struct. Mol. Biol.
, vol.11
, pp. 877-883
-
-
Uemura, S.1
Higuchi, H.2
Olivares, A.O.3
De La Cruz, E.M.4
Ishiwata, S.5
-
66
-
-
34848923743
-
Myosin V stepping mechanism
-
Cappello, G. et al. Myosin V stepping mechanism. Proc. Natl Acad. Sci. USA 104, 15328-15333 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 15328-15333
-
-
Cappello, G.1
-
67
-
-
77951978236
-
Direct observation of the myosin-Va power stroke and its reversal
-
The first direct evidence that the myosin power stroke can be physically reversed, which has important implications for motor regulation in cells
-
Sellers, J. R. & Veigel, C. Direct observation of the myosin-Va power stroke and its reversal. Nature Struct. Mol. Biol. 17, 590-595 (2010). The first direct evidence that the myosin power stroke can be physically reversed, which has important implications for motor regulation in cells.
-
(2010)
Nature Struct. Mol. Biol.
, vol.17
, pp. 590-595
-
-
Sellers, J.R.1
Veigel, C.2
-
68
-
-
26944449015
-
Load-dependent kinetics of myosin-V can explain its high processivity
-
Veigel, C., Schmitz, S., Wang, F. & Sellers, J. R. Load-dependent kinetics of myosin-V can explain its high processivity. Nature Cell Biol. 7, 861-869 (2005).
-
(2005)
Nature Cell Biol.
, vol.7
, pp. 861-869
-
-
Veigel, C.1
Schmitz, S.2
Wang, F.3
Sellers, J.R.4
-
69
-
-
0242609969
-
Load-dependent kinetics of force production by smooth muscle myosin measured with optical tweezers
-
Veigel, C., Molloy, J. E., Schmitz, S. & Kendrick-Jones, J. Load-dependent kinetics of force production by smooth muscle myosin measured with optical tweezers. Nature Cell Biol. 5, 980-986 (2003).
-
(2003)
Nature Cell Biol.
, vol.5
, pp. 980-986
-
-
Veigel, C.1
Molloy, J.E.2
Schmitz, S.3
Kendrick-Jones, J.4
-
70
-
-
62049083505
-
Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding
-
Kon, T. et al. Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding. Nature Struct. Mol. Biol. 16, 325-333 (2009).
-
(2009)
Nature Struct. Mol. Biol.
, vol.16
, pp. 325-333
-
-
Kon, T.1
-
71
-
-
0347623370
-
Kinesin moves by an asymmetric hand-over-hand mechanism
-
Asbury, C. L., Fehr, A. N. & Block, S. M. Kinesin moves by an asymmetric hand-over-hand mechanism. Science 302, 2130-2134 (2003).
-
(2003)
Science
, vol.302
, pp. 2130-2134
-
-
Asbury, C.L.1
Fehr, A.N.2
Block, S.M.3
-
72
-
-
0037832404
-
Myosin V walks hand-over-hand: Single fluorophore imaging with 1.5-nm localization
-
Yildiz, A. et al. Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization. Science 300, 2061-2065 (2003).
-
(2003)
Science
, vol.300
, pp. 2061-2065
-
-
Yildiz, A.1
-
73
-
-
0942279641
-
Kinesin walks hand-over-hand
-
Yildiz, A., Tomishige, M., Vale, R. D. & Selvin, P. R. Kinesin walks hand-over-hand. Science 303, 676-678 (2004).
-
(2004)
Science
, vol.303
, pp. 676-678
-
-
Yildiz, A.1
Tomishige, M.2
Vale, R.D.3
Selvin, P.R.4
-
74
-
-
17844385071
-
Differential labeling of myosin V heads with quantum dots allows direct visualization of hand-over-hand processivity
-
Warshaw, D. M. et al. Differential labeling of myosin V heads with quantum dots allows direct visualization of hand-over-hand processivity. Biophys. J. 88, L30-L32 (2005).
-
(2005)
Biophys. J.
, vol.88
-
-
Warshaw, D.M.1
-
75
-
-
69949092035
-
Direct observation of the binding state of the kinesin head to the microtubule
-
Guydosh, N. R. & Block, S. M. Direct observation of the binding state of the kinesin head to the microtubule. Nature 461, 125-128 (2009).
-
(2009)
Nature
, vol.461
, pp. 125-128
-
-
Guydosh, N.R.1
Block, S.M.2
-
76
-
-
33745033249
-
Myosin-V is a mechanical ratchet
-
Gebhardt, J. C. M., Clemen, A. E. M., Jaud, J. & Rief, M. Myosin-V is a mechanical ratchet. Proc. Natl Acad. Sci. USA 103, 8680-8685 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 8680-8685
-
-
Gebhardt, J.C.M.1
Clemen, A.E.M.2
Jaud, J.3
Rief, M.4
-
77
-
-
19644377414
-
Mechanics of the kinesin step
-
Carter, N. J. & Cross, R. A. Mechanics of the kinesin step. Nature 435, 308-312 (2005).
-
(2005)
Nature
, vol.435
, pp. 308-312
-
-
Carter, N.J.1
Cross, R.A.2
-
78
-
-
50649125304
-
Structure and mechanics of membrane proteins
-
Engel, A. & Gaub, H. E. Structure and mechanics of membrane proteins. Annu. Rev. Biochem. 77, 127-148 (2008).
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 127-148
-
-
Engel, A.1
Gaub, H.E.2
-
79
-
-
66349110264
-
Single molecule mechanics of the kinesin neck
-
Bornschlögl, T., Woehlke, G. & Rief, M. Single molecule mechanics of the kinesin neck. Proc. Natl Acad. Sci. USA 106, 6992-6997 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 6992-6997
-
-
Bornschlögl, T.1
Woehlke, G.2
Rief, M.3
-
80
-
-
4143107868
-
Resolving the molecular structure of microtubules under physiological conditions with scanning force microscopy
-
Schaap, I. A. T., de Pablo, P. J. & Schmidt, C. F. Resolving the molecular structure of microtubules under physiological conditions with scanning force microscopy. Eur. Biophys. J. 33, 462-467 (2004).
-
(2004)
Eur. Biophys. J.
, vol.33
, pp. 462-467
-
-
Schaap, I.A.T.1
De Pablo, P.J.2
Schmidt, C.F.3
-
81
-
-
33746784797
-
Elastic response, buckling, and instability of microtubules under radial indentation
-
Schaap, I. A. T., Carrasco, C., de Pablo, P. J., MacKintosh, F. C. & Schmidt, C. F. Elastic response, buckling, and instability of microtubules under radial indentation. Biophys. J. 91, 1521-1531 (2006).
-
(2006)
Biophys. J.
, vol.91
, pp. 1521-1531
-
-
Schaap, I.A.T.1
Carrasco, C.2
De Pablo, P.J.3
MacKintosh, F.C.4
Schmidt, C.F.5
-
82
-
-
34249008806
-
Tau protein binding forms a 1 nm thick layer along protofilaments without affecting the radial elasticity of microtubules
-
Schaap, I. A. T., Hoffmann, B., Carrasco, C., Merkel, R. & Schmidt, C. F. Tau protein binding forms a 1 nm thick layer along protofilaments without affecting the radial elasticity of microtubules. J. Struct. Biol. 158, 282-292 (2007).
-
(2007)
J. Struct. Biol.
, vol.158
, pp. 282-292
-
-
Schaap, I.A.T.1
Hoffmann, B.2
Carrasco, C.3
Merkel, R.4
Schmidt, C.F.5
-
83
-
-
43149090623
-
Cytoskeletal filaments and their associated proteins studied with atomic force microscopy
-
Schaap, I. A. T. et al. Cytoskeletal filaments and their associated proteins studied with atomic force microscopy. Biophys. J. (Suppl) 309A (2007).
-
(2007)
Biophys. J.
, Issue.SUPPL.
-
-
Schaap, I.A.T.1
-
84
-
-
78149285270
-
Video imaging of walking myosin V by high-speed atomic force microscopy
-
Kodera, N., Yamamoto, D., Ishikawa, R. & Ando, T. Video imaging of walking myosin V by high-speed atomic force microscopy. Nature 468, 72-76 (2010).
-
(2010)
Nature
, vol.468
, pp. 72-76
-
-
Kodera, N.1
Yamamoto, D.2
Ishikawa, R.3
Ando, T.4
-
85
-
-
34548457759
-
Tip-sample distance control using photothermal actuation of a small cantilever for highspeed atomic force microscopy
-
Yamashita, H. et al. Tip-sample distance control using photothermal actuation of a small cantilever for highspeed atomic force microscopy. Rev. Sci. Instr. 78, 083702 (2007).
-
(2007)
Rev. Sci. Instr.
, vol.78
, pp. 083702
-
-
Yamashita, H.1
-
86
-
-
67650762824
-
Super-resolution fluorescence microscopy
-
Huang, B., Bates, M. & Zhuang, X. W. Super-resolution fluorescence microscopy. Annu. Rev. Biochem. 78, 993-1016 (2009).
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 993-1016
-
-
Huang, B.1
Bates, M.2
Zhuang, X.W.3
-
87
-
-
0021717324
-
Detection of single microtubules in living cells - Particle transport can occur in both directions along the same microtubule
-
Hayden, J. H. & Allen, R. D. Detection of single microtubules in living cells - particle transport can occur in both directions along the same microtubule. J. Cell Biol. 99, 1785-1793 (1984).
-
(1984)
J. Cell Biol.
, vol.99
, pp. 1785-1793
-
-
Hayden, J.H.1
Allen, R.D.2
-
88
-
-
0022019741
-
Single microtubules from squid axoplams support bidirectional movement of organelles
-
Schnapp, B. J., Vale, R. D., Sheetz, M. P. & Reese, T. S. Single microtubules from squid axoplams support bidirectional movement of organelles. Cell 40, 455-462 (1985).
-
(1985)
Cell
, vol.40
, pp. 455-462
-
-
Schnapp, B.J.1
Vale, R.D.2
Sheetz, M.P.3
Reese, T.S.4
-
89
-
-
34250969819
-
The demonstration of bacterial flagella by means of the phase microscope
-
Burcik, E. & Plankenhorn, B. The demonstration of bacterial flagella by means of the phase microscope. Arch. Mikrobiol. 19, 435-437 (1953).
-
(1953)
Arch. Mikrobiol.
, vol.19
, pp. 435-437
-
-
Burcik, E.1
Plankenhorn, B.2
-
90
-
-
0022492523
-
Visualization of the dynamic instability of individual microtubules by dark-field microscopy
-
Horio, T. & Hotani, H. Visualization of the dynamic instability of individual microtubules by dark-field microscopy. Nature 321, 605-607 (1986).
-
(1986)
Nature
, vol.321
, pp. 605-607
-
-
Horio, T.1
Hotani, H.2
-
91
-
-
79951986650
-
Individual actin-filaments visualized by DIC (Nomarski) microscopy
-
Stemmer, A. Individual actin-filaments visualized by DIC (Nomarski) microscopy. Biol. Bull. 183, 360-361 (1992).
-
(1992)
Biol. Bull.
, vol.183
, pp. 360-361
-
-
Stemmer, A.1
-
92
-
-
0037474152
-
Zero-mode waveguides for single-molecule analysis at high concentrations
-
Levene, M. J. et al. Zero-mode waveguides for single-molecule analysis at high concentrations. Science 299, 682-686 (2003).
-
(2003)
Science
, vol.299
, pp. 682-686
-
-
Levene, M.J.1
-
93
-
-
57549107708
-
Folding and unfolding single RNA molecules under tension
-
Woodside, M. T., García-García, C. & Block, S. M. Folding and unfolding single RNA molecules under tension. Curr. Opin. Chem. Biol. 12, 640-646 (2008).
-
(2008)
Curr. Opin. Chem. Biol.
, vol.12
, pp. 640-646
-
-
Woodside, M.T.1
García-García, C.2
Block, S.M.3
-
94
-
-
77649266957
-
Plasmonic nanorod absorbers as orientation sensors
-
Chang, W. S., Ha, J. W., Slaughter, L. S. & Link, S. Plasmonic nanorod absorbers as orientation sensors. Proc. Natl Acad. Sci. USA 107, 2781-2786 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 2781-2786
-
-
Chang, W.S.1
Ha, J.W.2
Slaughter, L.S.3
Link, S.4
-
95
-
-
33847680889
-
Dynamics of the unbound head during myosin V processive translocation
-
Dunn, A. R. & Spudich, J. A. Dynamics of the unbound head during myosin V processive translocation. Nature Struct. Mol. Biol. 14, 246-248 (2007).
-
(2007)
Nature Struct. Mol. Biol.
, vol.14
, pp. 246-248
-
-
Dunn, A.R.1
Spudich, J.A.2
-
96
-
-
0033953433
-
Single-target molecule detection with nonbleaching multicolor optical immunolabels
-
Schultz, S., Smith, D. R., Mock, J. J. & Schultz, D. A. Single-target molecule detection with nonbleaching multicolor optical immunolabels. Proc. Natl Acad. Sci. USA 97, 996-1001 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 996-1001
-
-
Schultz, S.1
Smith, D.R.2
Mock, J.J.3
Schultz, D.A.4
-
97
-
-
0020659058
-
Total internal reflection fluorescent microscopy
-
Axelrod, D., Thompson, N. L. & Burghardt, T. P. Total internal reflection fluorescent microscopy. J. Microsc. 129, 19-28 (1983).
-
(1983)
J. Microsc.
, vol.129
, pp. 19-28
-
-
Axelrod, D.1
Thompson, N.L.2
Burghardt, T.P.3
-
98
-
-
0037804221
-
Myosin motors walk the walk
-
Molloy, J. E. & Veigel, C. Myosin motors walk the walk. Science 300, 2045-2046 (2003).
-
(2003)
Science
, vol.300
, pp. 2045-2046
-
-
Molloy, J.E.1
Veigel, C.2
-
99
-
-
13444292841
-
Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time
-
Churchman, L. S., Okten, Z., Rock, R. S., Dawson, J. F. & Spudich, J. A. Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time. Proc. Natl Acad. Sci. USA 102, 1419-1423 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 1419-1423
-
-
Churchman, L.S.1
Okten, Z.2
Rock, R.S.3
Dawson, J.F.4
Spudich, J.A.5
-
100
-
-
77956634165
-
Switch between large hand-over-hand and small inchworm-like steps in myosin VI
-
Nishikawa, S. et al. Switch between large hand-over-hand and small inchworm-like steps in myosin VI. Cell 142, 879-888 (2010).
-
(2010)
Cell
, vol.142
, pp. 879-888
-
-
Nishikawa, S.1
-
101
-
-
34948867142
-
Myosin-V makes two brownian 90° rotations per 36-nm step
-
Komori, Y., Iwane, A. H. & Yanagida, T. Myosin-V makes two brownian 90° rotations per 36-nm step. Nature Struct. Mol. Biol. 14, 968-973 (2007).
-
(2007)
Nature Struct. Mol. Biol.
, vol.14
, pp. 968-973
-
-
Komori, Y.1
Iwane, A.H.2
Yanagida, T.3
-
102
-
-
2342582682
-
Single-molecule high-resolution imaging with photobleaching
-
Gordon, M. P., Ha, T. & Selvin, P. R. Single-molecule high-resolution imaging with photobleaching. Proc. Natl Acad. Sci. USA 101, 6462-6465 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 6462-6465
-
-
Gordon, M.P.1
Ha, T.2
Selvin, P.R.3
-
103
-
-
3843104585
-
Nanometer-localized multiple single-molecule fluorescence microscopy
-
Qu, X. H., Wu, D., Mets, L. & Scherer, N. F. Nanometer-localized multiple single-molecule fluorescence microscopy. Proc. Natl Acad. Sci. USA 101, 11298-11303 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 11298-11303
-
-
Qu, X.H.1
Wu, D.2
Mets, L.3
Scherer, N.F.4
-
104
-
-
23244444140
-
Interhead distance measurements in myosin VI via SHRImP support a simplified hand-over-hand model
-
Balci, H., Ha, T., Sweeney, H. L. & Selvin, P. R. Interhead distance measurements in myosin VI via SHRImP support a simplified hand-over-hand model. Biophys. J. 89, 413-417 (2005).
-
(2005)
Biophys. J.
, vol.89
, pp. 413-417
-
-
Balci, H.1
Ha, T.2
Sweeney, H.L.3
Selvin, P.R.4
-
105
-
-
36749068925
-
How kinesin waits between steps
-
An important study that applied single-molecule FRET to analyse the relative position of the two heads of a kinesin motor during processive movement
-
Mori, T., Vale, R. D. & Tomishige, M. How kinesin waits between steps. Nature 450, 750-754 (2007). An important study that applied single-molecule FRET to analyse the relative position of the two heads of a kinesin motor during processive movement.
-
(2007)
Nature
, vol.450
, pp. 750-754
-
-
Mori, T.1
Vale, R.D.2
Tomishige, M.3
-
106
-
-
0012112253
-
Orientational imaging of single molecules by annular illumination
-
Sick, B., Hecht, B. & Novotny, L. Orientational imaging of single molecules by annular illumination. Phys. Rev. Lett. 85, 4482-4485 (2000).
-
(2000)
Phys. Rev. Lett.
, vol.85
, pp. 4482-4485
-
-
Sick, B.1
Hecht, B.2
Novotny, L.3
-
107
-
-
33646237832
-
Defocused orientation and position imaging (DOPI) of myosin V
-
Toprak, E. et al. Defocused orientation and position imaging (DOPI) of myosin V. Proc. Natl Acad. Sci. USA 103, 6495-6499 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 6495-6499
-
-
Toprak, E.1
-
108
-
-
0034995132
-
ADP-induced rocking of the kinesin motor domain revealed by single-molecule fluorescence polarization microscopy
-
Sosa, H., Peterman, E. J. G., Moerner, W. E. & Goldstein, L. S. B. ADP-induced rocking of the kinesin motor domain revealed by single-molecule fluorescence polarization microscopy. Nature Struct. Biol. 8, 540-544 (2001).
-
(2001)
Nature Struct. Biol.
, vol.8
, pp. 540-544
-
-
Sosa, H.1
Peterman, E.J.G.2
Moerner, W.E.3
Goldstein, L.S.B.4
-
109
-
-
0033615015
-
Dynamic measurement of myosin light-chain-domain tilt and twist in muscle contraction
-
Corrie, J. E. T. et al. Dynamic measurement of myosin light-chain-domain tilt and twist in muscle contraction. Nature 400, 425-430 (1999).
-
(1999)
Nature
, vol.400
, pp. 425-430
-
-
Corrie, J.E.T.1
-
110
-
-
0037468838
-
Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization
-
Forkey, J. N., Quinlan, M. E., Shaw, M. A., Corrie, J. E. T. & Goldman, Y. E. Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization. Nature 422, 399-404 (2003).
-
(2003)
Nature
, vol.422
, pp. 399-404
-
-
Forkey, J.N.1
Quinlan, M.E.2
Shaw, M.A.3
Corrie, J.E.T.4
Goldman, Y.E.5
-
111
-
-
34249948276
-
Myosin V walks by lever action and Brownian motion
-
Shiroguchi, K. & Kinosita, K. Myosin V walks by lever action and Brownian motion. Science 316, 1208-1212 (2007).
-
(2007)
Science
, vol.316
, pp. 1208-1212
-
-
Shiroguchi, K.1
Kinosita, K.2
-
112
-
-
8544226261
-
A series of related nucleotide analogues that aids optimization of fluorescence signals in probing the mechanism of P-loop ATPases, such as actomyosin
-
Webb, M. R., Reid, G. P., Munasinghe, V. R. N. & Corrie, J. E. T. A series of related nucleotide analogues that aids optimization of fluorescence signals in probing the mechanism of P-loop ATPases, such as actomyosin. Biochemistry 43, 14463-14471 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 14463-14471
-
-
Webb, M.R.1
Reid, G.P.2
Munasinghe, V.R.N.3
Corrie, J.E.T.4
-
113
-
-
0032559298
-
Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin
-
Ishijima, A. et al. Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin. Cell 92, 161-171 (1998).
-
(1998)
Cell
, vol.92
, pp. 161-171
-
-
Ishijima, A.1
-
114
-
-
2642522184
-
Combining optical trapping and single-molecule fluorescence spectroscopy: Enhanced photobleaching of fluorophores
-
van Dijk, M. A., Kapitein, L. C., van Mameren, J., Schmidt, C. F. & Peterman, E. J. G. Combining optical trapping and single-molecule fluorescence spectroscopy: enhanced photobleaching of fluorophores. J. Phys. Chem. B 108, 6479-6484 (2004).
-
(2004)
J. Phys. Chem. B
, vol.108
, pp. 6479-6484
-
-
Van Dijk, M.A.1
Kapitein, L.C.2
Van Mameren, J.3
Schmidt, C.F.4
Peterman, E.J.G.5
-
115
-
-
17444366080
-
Simultaneous, coincident optical trapping and single-molecule fluorescence
-
Lang, M. J., Fordyce, P. M., Engh, A. M., Neuman, K. C. & Block, S. M. Simultaneous, coincident optical trapping and single-molecule fluorescence. Nature Methods 1, 133-139 (2004).
-
(2004)
Nature Methods
, vol.1
, pp. 133-139
-
-
Lang, M.J.1
Fordyce, P.M.2
Engh, A.M.3
Neuman, K.C.4
Block, S.M.5
-
116
-
-
33746702015
-
Interlaced optical force-fluorescence measurements for single molecule biophysics
-
Brau, R. R., Tarsa, P. B., Ferrer, J. M., Lee, P. & Lang, M. J. Interlaced optical force-fluorescence measurements for single molecule biophysics. Biophys. J. 91, 1069-1077 (2006).
-
(2006)
Biophys. J.
, vol.91
, pp. 1069-1077
-
-
Brau, R.R.1
Tarsa, P.B.2
Ferrer, J.M.3
Lee, P.4
Lang, M.J.5
-
117
-
-
0037119610
-
Photothermal imaging of nanometer-sized metal particles among scatterers
-
Boyer, D., Tamarat, P., Maali, A., Lounis, B. & Orrit, M. Photothermal imaging of nanometer-sized metal particles among scatterers. Science 297, 1160-1163 (2002).
-
(2002)
Science
, vol.297
, pp. 1160-1163
-
-
Boyer, D.1
Tamarat, P.2
Maali, A.3
Lounis, B.4
Orrit, M.5
-
118
-
-
33947697260
-
Automatic detection of single fluorophores in live cells
-
Mashanov, G. I. & Molloy, J. E. Automatic detection of single fluorophores in live cells. Biophys. J. 92, 2199-2211 (2007).
-
(2007)
Biophys. J.
, vol.92
, pp. 2199-2211
-
-
Mashanov, G.I.1
Molloy, J.E.2
-
119
-
-
77952215650
-
Optimized localization analysis for single-molecule tracking and super-resolution microscopy
-
Mortensen, K. I., Churchman, L. S., Spudich, J. A. & Flyvbjerg, H. Optimized localization analysis for single-molecule tracking and super-resolution microscopy. Nature Methods 7, 377-381 (2010).
-
(2010)
Nature Methods
, vol.7
, pp. 377-381
-
-
Mortensen, K.I.1
Churchman, L.S.2
Spudich, J.A.3
Flyvbjerg, H.4
-
120
-
-
33646950699
-
The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends
-
Describes a single-molecule fluorescence assay that showed that the microtubule-depolymerizing Kinesin-13 MCAK (mitotic centromere-associated kinesin; also known as KIF2C) uses 1D diffusion to reach the microtubule ends
-
Helenius, J., Brouhard, G., Kalaidzidis, Y., Diez, S. & Howard, J. The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends. Nature 441, 115-119 (2006). Describes a single-molecule fluorescence assay that showed that the microtubule-depolymerizing Kinesin-13 MCAK (mitotic centromere-associated kinesin; also known as KIF2C) uses 1D diffusion to reach the microtubule ends.
-
(2006)
Nature
, vol.441
, pp. 115-119
-
-
Helenius, J.1
Brouhard, G.2
Kalaidzidis, Y.3
Diez, S.4
Howard, J.5
-
121
-
-
0033582814
-
A processive single-headed motor: Kinesin superfamily protein KIF1A
-
Okada, Y. & Hirokawa, N. A processive single-headed motor: kinesin superfamily protein KIF1A. Science 283, 1152-1157 (1999).
-
(1999)
Science
, vol.283
, pp. 1152-1157
-
-
Okada, Y.1
Hirokawa, N.2
-
122
-
-
0034681137
-
Mechanism of the single-headed processivity: Diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin
-
Okada, Y. & Hirokawa, N. Mechanism of the single-headed processivity: diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin. Proc. Natl Acad. Sci. USA 97, 640-645 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 640-645
-
-
Okada, Y.1
Hirokawa, N.2
-
123
-
-
70350425612
-
Diffusive movement of processive Kinesin-1 on microtubules
-
Lu, H. L., Ali, M. Y., Bookwalter, C. S., Warshaw, D. M. & Trybus, K. M. Diffusive movement of processive Kinesin-1 on microtubules. Traffic 10, 1429-1438 (2009).
-
(2009)
Traffic
, vol.10
, pp. 1429-1438
-
-
Lu, H.L.1
Ali, M.Y.2
Bookwalter, C.S.3
Warshaw, D.M.4
Trybus, K.M.5
-
124
-
-
34047262039
-
Myosin Va maneuvers through actin intersections and diffuses along microtubules
-
Ali, M. Y. et al. Myosin Va maneuvers through actin intersections and diffuses along microtubules. Proc. Natl Acad. Sci. USA 104, 4332-4336 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 4332-4336
-
-
Ali, M.Y.1
-
125
-
-
42449129759
-
Myosin V and kinesin act as tethers to enhance each others' processivity
-
Ali, M. Y., Lu, H. L., Bookwalter, C. S., Warshaw, D. M. & Trybus, K. M. Myosin V and kinesin act as tethers to enhance each others' processivity. Proc. Natl Acad. Sci. USA 105, 4691-4696 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 4691-4696
-
-
Ali, M.Y.1
Lu, H.L.2
Bookwalter, C.S.3
Warshaw, D.M.4
Trybus, K.M.5
-
126
-
-
70149111601
-
Kinesin-8 motors act cooperatively to mediate length-dependent microtubule depolymerization
-
Varga, V., Leduc, C., Bormuth, V., Diez, S. & Howard, J. Kinesin-8 motors act cooperatively to mediate length-dependent microtubule depolymerization. Cell 138, 1174-1183 (2009).
-
(2009)
Cell
, vol.138
, pp. 1174-1183
-
-
Varga, V.1
Leduc, C.2
Bormuth, V.3
Diez, S.4
Howard, J.5
-
127
-
-
55249101931
-
Microtubule-driven multimerization recruits ase1p onto overlapping microtubules
-
Kapitein, L. C. et al. Microtubule-driven multimerization recruits ase1p onto overlapping microtubules. Curr. Biol. 18, 1713-1717 (2008).
-
(2008)
Curr. Biol.
, vol.18
, pp. 1713-1717
-
-
Kapitein, L.C.1
-
128
-
-
18344371892
-
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
-
Kapitein, L. C. et al. The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. Nature 435, 114-118 (2005).
-
(2005)
Nature
, vol.435
, pp. 114-118
-
-
Kapitein, L.C.1
-
129
-
-
57649086182
-
The homotetrameric Kinesin-5 KLP61F preferentially crosslinks microtubules into antiparallel orientations
-
van den Wildenberg, S. et al. The homotetrameric Kinesin-5 KLP61F preferentially crosslinks microtubules into antiparallel orientations. Curr. Biol. 18, 1860-1864 (2008).
-
(2008)
Curr. Biol.
, vol.18
, pp. 1860-1864
-
-
Van Den Wildenberg, S.1
-
130
-
-
33747624954
-
Allosteric inhibition of Kinesin-5 modulates its processive directional motility
-
Kwok, B. H. et al. Allosteric inhibition of Kinesin-5 modulates its processive directional motility. Nature Chem. Biol. 2, 480-485 (2006).
-
(2006)
Nature Chem. Biol.
, vol.2
, pp. 480-485
-
-
Kwok, B.H.1
-
131
-
-
77953081400
-
The effect of monastrol on the processive motility of a dimeric Kinesin-5 head/Kinesin-1 stalk chimera
-
Lakämper, S. et al. The effect of monastrol on the processive motility of a dimeric Kinesin-5 head/Kinesin-1 stalk chimera. J. Mol. Biol. 399, 1-8 (2010).
-
(2010)
J. Mol. Biol.
, vol.399
, pp. 1-8
-
-
Lakämper, S.1
-
132
-
-
49749107045
-
Microtubule cross-linking triggers the directional motility of Kinesin-5
-
Single-molecule fluorescence was used here to observe the cargo-dependent switching on and off of a bipolar mitotic kinesin motor
-
Kapitein, L. C. et al. Microtubule cross-linking triggers the directional motility of Kinesin-5. J. Cell Biol. 182, 421-428 (2008). Single-molecule fluorescence was used here to observe the cargo-dependent switching on and off of a bipolar mitotic kinesin motor.
-
(2008)
J. Cell Biol.
, vol.182
, pp. 421-428
-
-
Kapitein, L.C.1
-
133
-
-
0035033890
-
Autofluorescent proteins in single-molecule research: Applications to live cell imaging microscopy
-
Harms, G. S., Cognet, L., Lommerse, P. H. M., Blab, G. A. & Schmidt, T. Autofluorescent proteins in single-molecule research: applications to live cell imaging microscopy. Biophys. J. 80, 2396-2408 (2001).
-
(2001)
Biophys. J.
, vol.80
, pp. 2396-2408
-
-
Harms, G.S.1
Cognet, L.2
Lommerse, P.H.M.3
Blab, G.A.4
Schmidt, T.5
-
135
-
-
2442595175
-
The spatial and temporal dynamics of pleckstrin homology domain binding at the plasma membrane measured by imaging single molecules in live mouse myoblasts
-
Mashanov, G. I., Tacon, D., Peckham, M. & Molloy, J. E. The spatial and temporal dynamics of pleckstrin homology domain binding at the plasma membrane measured by imaging single molecules in live mouse myoblasts. J. Biol. Chem. 279, 15274-15280 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15274-15280
-
-
Mashanov, G.I.1
Tacon, D.2
Peckham, M.3
Molloy, J.E.4
-
136
-
-
20344382542
-
Kinesin and dynein move a peroxisome in vivo: A tug-of-war or coordinated movement?
-
Kural, C. et al. Kinesin and dynein move a peroxisome in vivo: a tug-of-war or coordinated movement? Science 308, 1469-1472 (2005).
-
(2005)
Science
, vol.308
, pp. 1469-1472
-
-
Kural, C.1
-
137
-
-
30344436982
-
Observation of individual microtubule motor steps in living cells with endocytosed quantum dots
-
Nan, X. L., Sims, P. A., Chen, P. & Xie, X. S. Observation of individual microtubule motor steps in living cells with endocytosed quantum dots. J. Phys. Chem. B 109, 24220-24224 (2005).
-
(2005)
J. Phys. Chem. B
, vol.109
, pp. 24220-24224
-
-
Nan, X.L.1
Sims, P.A.2
Chen, P.3
Xie, X.S.4
-
138
-
-
34547477550
-
Detection of fractional steps in cargo movement by the collective operation of Kinesin-1 motors
-
Leduc, C., Ruhnow, F., Howard, J. & Diez, S. Detection of fractional steps in cargo movement by the collective operation of Kinesin-1 motors. Proc. Natl Acad. Sci. USA 104, 10847-10852 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 10847-10852
-
-
Leduc, C.1
Ruhnow, F.2
Howard, J.3
Diez, S.4
-
139
-
-
68049143191
-
Velocity, processivity, and individual steps of single myosin V molecules in live cells
-
Pierobon, P. et al. Velocity, processivity, and individual steps of single myosin V molecules in live cells. Biophys. J. 96, 4268-4275 (2009).
-
(2009)
Biophys. J.
, vol.96
, pp. 4268-4275
-
-
Pierobon, P.1
-
140
-
-
68949125193
-
Random walk of processive, quantum dot-labeled myosin Va molecules within the actin cortex of COS-7 Cells
-
References 139 and 140 are landmark papers reporting the single-molecule observation of quantum-dot-labelled myosin V in cells
-
Nelson, S. R., Ali, M. Y., Trybus, K. M. & Warshaw, D. M. Random walk of processive, quantum dot-labeled myosin Va molecules within the actin cortex of COS-7 Cells. Biophys. J. 97, 509-518 (2009). References 139 and 140 are landmark papers reporting the single-molecule observation of quantum-dot-labelled myosin V in cells.
-
(2009)
Biophys. J.
, vol.97
, pp. 509-518
-
-
Nelson, S.R.1
Ali, M.Y.2
Trybus, K.M.3
Warshaw, D.M.4
-
141
-
-
34250372604
-
Tracking single kinesin molecules in the cytoplasm of mammalian cells
-
Cai, D. W., Verhey, K. J. & Meyhofer, E. Tracking single kinesin molecules in the cytoplasm of mammalian cells. Biophys. J. 92, 4137-4144 (2007).
-
(2007)
Biophys. J.
, vol.92
, pp. 4137-4144
-
-
Cai, D.W.1
Verhey, K.J.2
Meyhofer, E.3
-
143
-
-
0034909695
-
Analysis of single-molecule mechanical recordings: Application to acto-myosin interactions
-
Knight, A. E., Veigel, C., Chambers, C. & Molloy, J. E. Analysis of single-molecule mechanical recordings: application to acto-myosin interactions. Prog. Biophys. Mol. Biol. 77, 45-72 (2001).
-
(2001)
Prog. Biophys. Mol. Biol.
, vol.77
, pp. 45-72
-
-
Knight, A.E.1
Veigel, C.2
Chambers, C.3
Molloy, J.E.4
-
144
-
-
0036660188
-
Lights, action: Optical tweezers
-
Molloy, J. E. & Padgett, M. J. Lights, action: optical tweezers. Contemp. Phys. 43, 241-258 (2002).
-
(2002)
Contemp. Phys.
, vol.43
, pp. 241-258
-
-
Molloy, J.E.1
Padgett, M.J.2
-
145
-
-
0029976424
-
Quantitative measurements of force and displacement using an optical trap
-
Simmons, R. M., Finer, J. T., Chu, S. & Spudich, J. A. Quantitative measurements of force and displacement using an optical trap. Biophys. J. 70, 1813-1822 (1996).
-
(1996)
Biophys. J.
, vol.70
, pp. 1813-1822
-
-
Simmons, R.M.1
Finer, J.T.2
Chu, S.3
Spudich, J.A.4
-
146
-
-
0031035189
-
Actin filament mechanics in the laser trap
-
Dupuis, D. E., Guilford, W. H., Wu, J. & Warshaw, D. M. Actin filament mechanics in the laser trap. J. Muscle Res. Cell Motil. 18, 17-30 (1997).
-
(1997)
J. Muscle Res. Cell Motil.
, vol.18
, pp. 17-30
-
-
Dupuis, D.E.1
Guilford, W.H.2
Wu, J.3
Warshaw, D.M.4
-
147
-
-
0030878880
-
Detection of single-molecule interactions using correlated thermal diffusion
-
Mehta, A. D., Finer, J. T. & Spudich, J. A. Detection of single-molecule interactions using correlated thermal diffusion. Proc. Natl Acad. Sci. USA 94, 7927-7931 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 7927-7931
-
-
Mehta, A.D.1
Finer, J.T.2
Spudich, J.A.3
-
148
-
-
65249184511
-
Leveraging single protein polymers to measure flexural rigidity
-
van Mameren, J., Vermeulen, K. C., Gittes, F. & Schmidt, C. F. Leveraging single protein polymers to measure flexural rigidity. J. Phys. Chem. B 113, 3837-3844 (2009).
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 3837-3844
-
-
Van Mameren, J.1
Vermeulen, K.C.2
Gittes, F.3
Schmidt, C.F.4
-
149
-
-
0031656226
-
The stiffness of rabbit skeletal actomyosin cross-bridges determined with an optical tweezers transducer
-
Veigel, C., Bartoo, M. L., White, D. C. S., Sparrow, J. C. & Molloy, J. E. The stiffness of rabbit skeletal actomyosin cross-bridges determined with an optical tweezers transducer. Biophys. J. 75, 1424-1438 (1998).
-
(1998)
Biophys. J.
, vol.75
, pp. 1424-1438
-
-
Veigel, C.1
Bartoo, M.L.2
White, D.C.S.3
Sparrow, J.C.4
Molloy, J.E.5
-
150
-
-
0035910049
-
Mapping the actin filament with myosin
-
Steffen, W., Smith, D., Simmons, R. & Sleep, J. Mapping the actin filament with myosin. Proc. Natl Acad. Sci. USA 98, 14949-14954 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 14949-14954
-
-
Steffen, W.1
Smith, D.2
Simmons, R.3
Sleep, J.4
-
151
-
-
33645758327
-
Force generation in single conventional actomyosin complexes under high dynamic load
-
Takagi, Y., Homsher, E. E., Goldman, Y. E. & Shuman, H. Force generation in single conventional actomyosin complexes under high dynamic load. Biophys. J. 90, 1295-1307 (2006).
-
(2006)
Biophys. J.
, vol.90
, pp. 1295-1307
-
-
Takagi, Y.1
Homsher, E.E.2
Goldman, Y.E.3
Shuman, H.4
-
152
-
-
0027472356
-
Micromanipulation by multiple optical traps created by a single fast scanning trap integrated with the bilateral confocal scanning laser microscope
-
Visscher, K., Brakenhoff, G. J. & Krol, J. J. Micromanipulation by multiple optical traps created by a single fast scanning trap integrated with the bilateral confocal scanning laser microscope. Cytometry 14, 105-114 (1993).
-
(1993)
Cytometry
, vol.14
, pp. 105-114
-
-
Visscher, K.1
Brakenhoff, G.J.2
Krol, J.J.3
-
153
-
-
41549169619
-
Precision steering of an optical trap by electro-optic deflection
-
Valentine, M. T. et al. Precision steering of an optical trap by electro-optic deflection. Opt. Lett. 33, 599-601 (2008).
-
(2008)
Opt. Lett.
, vol.33
, pp. 599-601
-
-
Valentine, M.T.1
-
154
-
-
0033536183
-
Single kinesin molecules studied with a molecular force clamp
-
The application of a single-molecule force clamp in an optical trap assay made it possible for these authors to study the force-dependence of the kinesin cycle with unprecedented accuracy
-
Visscher, K., Schnitzer, M. J. & Block, S. M. Single kinesin molecules studied with a molecular force clamp. Nature 400, 184-189 (1999). The application of a single-molecule force clamp in an optical trap assay made it possible for these authors to study the force-dependence of the kinesin cycle with unprecedented accuracy.
-
(1999)
Nature
, vol.400
, pp. 184-189
-
-
Visscher, K.1
Schnitzer, M.J.2
Block, S.M.3
-
155
-
-
33744987629
-
Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro
-
Valentine, M. T., Fordyce, P. M., Krzysiak, T. C., Gilbert, S. P. & Block, S. M. Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro. Nature Cell Biol. 8, 470-476 (2006).
-
(2006)
Nature Cell Biol.
, vol.8
, pp. 470-476
-
-
Valentine, M.T.1
Fordyce, P.M.2
Krzysiak, T.C.3
Gilbert, S.P.4
Block, S.M.5
-
156
-
-
0037418263
-
Probing the kinesin reaction cycle with a 2D optical force clamp
-
Block, S. M., Asbury, C. L., Shaevitz, J. W. & Lang, M. J. Probing the kinesin reaction cycle with a 2D optical force clamp. Proc. Natl Acad. Sci. USA 100, 2351-2356 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 2351-2356
-
-
Block, S.M.1
Asbury, C.L.2
Shaevitz, J.W.3
Lang, M.J.4
-
157
-
-
0034662912
-
Myosin-V stepping kinetics: A molecular model for processivity
-
Rief, M. et al. Myosin-V stepping kinetics: a molecular model for processivity. Proc. Natl Acad. Sci. USA 97, 9482-9486 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 9482-9486
-
-
Rief, M.1
-
158
-
-
0032582494
-
Force and velocity measured for single molecules of RNA polymerase
-
Wang, M. D. et al. Force and velocity measured for single molecules of RNA polymerase. Science 282, 902-907 (1998).
-
(1998)
Science
, vol.282
, pp. 902-907
-
-
Wang, M.D.1
-
159
-
-
28844460238
-
Passive all-optical force clamp for high-resolution laser trapping
-
Greenleaf, W. J., Woodside, M. T., Abbondanzieri, E. A. & Block, S. M. Passive all-optical force clamp for high-resolution laser trapping. Phys. Rev. Lett. 95, 208102 (2005).
-
(2005)
Phys. Rev. Lett.
, vol.95
, pp. 208102
-
-
Greenleaf, W.J.1
Woodside, M.T.2
Abbondanzieri, E.A.3
Block, S.M.4
-
160
-
-
28544432440
-
Direct observation of base-pair stepping by RNA polymerase
-
Abbondanzieri, E. A., Greenleaf, W. J., Shaevitz, J. W., Landick, R. & Block, S. M. Direct observation of base-pair stepping by RNA polymerase. Nature 438, 460-465 (2005).
-
(2005)
Nature
, vol.438
, pp. 460-465
-
-
Abbondanzieri, E.A.1
Greenleaf, W.J.2
Shaevitz, J.W.3
Landick, R.4
Block, S.M.5
-
161
-
-
38849204944
-
Direct observation of hierarchical folding in single riboswitch aptamers
-
Greenleaf, W. J., Frieda, K. L., Foster, D. A. N., Woodside, M. T. & Block, S. M. Direct observation of hierarchical folding in single riboswitch aptamers. Science 319, 630-633 (2008).
-
(2008)
Science
, vol.319
, pp. 630-633
-
-
Greenleaf, W.J.1
Frieda, K.L.2
Foster, D.A.N.3
Woodside, M.T.4
Block, S.M.5
-
162
-
-
33750970551
-
Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid
-
Woodside, M. T. et al. Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid. Science 314, 1001-1004 (2006).
-
(2006)
Science
, vol.314
, pp. 1001-1004
-
-
Woodside, M.T.1
-
163
-
-
0031930529
-
Thermal noise limitations on micromechanical experiments
-
Gittes, F. & Schmidt, C. F. Thermal noise limitations on micromechanical experiments. Eur. Biophys. J. 27, 75-81 (1998).
-
(1998)
Eur. Biophys. J.
, vol.27
, pp. 75-81
-
-
Gittes, F.1
Schmidt, C.F.2
-
164
-
-
0031961707
-
-
Laser Tweezers in Cell Biology, Ed. M. P. Sheetz, Academic Press Inc., San Diego, A basic introduction to the analysis of single-molecule optical-trap data and a discussion of relevant noise sources
-
Gittes, F. & Schmidt, C. F. in Methods in Cell Biology, Vol. 55 (Laser Tweezers in Cell Biology) (Ed. M. P. Sheetz) 129-156 (Academic Press Inc., San Diego, 1998). A basic introduction to the analysis of single-molecule optical-trap data and a discussion of relevant noise sources.
-
(1998)
Methods in Cell Biology
, vol.55
, pp. 129-156
-
-
Gittes, F.1
Schmidt, C.F.2
-
165
-
-
0034757969
-
Hidden-Markov methods for the analysis of singlemolecule actomyosin displacement data: The variance-Hidden-Markov method
-
Smith, D. A., Steffen, W., Simmons, R. M. & Sleep, J. Hidden-Markov methods for the analysis of singlemolecule actomyosin displacement data: the variance-Hidden-Markov method. Biophys. J. 81, 2795-2816 (2001).
-
(2001)
Biophys. J.
, vol.81
, pp. 2795-2816
-
-
Smith, D.A.1
Steffen, W.2
Simmons, R.M.3
Sleep, J.4
-
166
-
-
30444437723
-
Two independent mechanical events in the interaction cycle of skeletal muscle myosin with actin
-
Capitanio, M. et al. Two independent mechanical events in the interaction cycle of skeletal muscle myosin with actin. Proc. Natl Acad. Sci. USA 103, 87-92 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 87-92
-
-
Capitanio, M.1
-
167
-
-
44049094435
-
Single-molecule measurement of the stiffness of the rigor myosin head
-
Lewalle, A., Steffen, W., Stevenson, O., Ouyang, Z. Q. & Sleep, J. Single-molecule measurement of the stiffness of the rigor myosin head. Biophys. J. 94, 2160-2169 (2008).
-
(2008)
Biophys. J.
, vol.94
, pp. 2160-2169
-
-
Lewalle, A.1
Steffen, W.2
Stevenson, O.3
Ouyang, Z.Q.4
Sleep, J.5
-
168
-
-
2442609583
-
A monomeric myosin VI with a large working stroke
-
Lister, I. et al. A monomeric myosin VI with a large working stroke. EMBO J. 23, 1729-1738 (2004).
-
(2004)
EMBO J.
, vol.23
, pp. 1729-1738
-
-
Lister, I.1
-
169
-
-
46849089895
-
Myosin I can act as a molecular force sensor
-
Laakso, J. M., Lewis, J. H., Shuman, H. & Ostap, E. M. Myosin I can act as a molecular force sensor. Science 321, 133-136 (2008).
-
(2008)
Science
, vol.321
, pp. 133-136
-
-
Laakso, J.M.1
Lewis, J.H.2
Shuman, H.3
Ostap, E.M.4
-
170
-
-
77049091811
-
The lever arm effects a mechanical asymmetry of the myosin-V-actin bond
-
Gebhardt, J. C. M., Okten, Z. & Rief, M. The lever arm effects a mechanical asymmetry of the myosin-V-actin bond. Biophys. J. 98, 277-281 (2010).
-
(2010)
Biophys. J.
, vol.98
, pp. 277-281
-
-
Gebhardt, J.C.M.1
Okten, Z.2
Rief, M.3
-
171
-
-
77949874333
-
Robust processivity of myosin V under off-axis loads
-
Oguchi, Y. et al. Robust processivity of myosin V under off-axis loads. Nature Chem. Biol. 6, 300-305 (2010).
-
(2010)
Nature Chem. Biol.
, vol.6
, pp. 300-305
-
-
Oguchi, Y.1
-
172
-
-
0037390461
-
Loading direction regulates the affinity of ADP for kinesin
-
Uemura, S. & Ishiwata, S. Loading direction regulates the affinity of ADP for kinesin. Nature Struct. Biol. 10, 308-311 (2003).
-
(2003)
Nature Struct. Biol.
, vol.10
, pp. 308-311
-
-
Uemura, S.1
Ishiwata, S.2
-
173
-
-
0025251665
-
Force generation of organelle transport measured in vivo by an infrared laser trap
-
Ashkin, A., Schutze, K., Dziedzic, J. M., Euteneuer, U. & Schliwa, M. Force generation of organelle transport measured in vivo by an infrared laser trap. Nature 348, 346-348 (1990).
-
(1990)
Nature
, vol.348
, pp. 346-348
-
-
Ashkin, A.1
Schutze, K.2
Dziedzic, J.M.3
Euteneuer, U.4
Schliwa, M.5
-
174
-
-
0032548920
-
Developmental regulation of vesicle transport in Drosophila embryos: Forces and kinetics
-
Welte, M. A., Gross, S. P., Postner, M., Block, S. M. & Wieschaus, E. F. Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics. Cell 92, 547-557 (1998).
-
(1998)
Cell
, vol.92
, pp. 547-557
-
-
Welte, M.A.1
Gross, S.P.2
Postner, M.3
Block, S.M.4
Wieschaus, E.F.5
-
175
-
-
57149145788
-
Consequences of motor copy number on the intracellular transport of Kinesin-1-driven lipid droplets
-
Shubeita, G. T. et al. Consequences of motor copy number on the intracellular transport of Kinesin-1-driven lipid droplets. Cell 135, 1098-1107 (2008).
-
(2008)
Cell
, vol.135
, pp. 1098-1107
-
-
Shubeita, G.T.1
-
176
-
-
0037139923
-
Optical trapping near resonance absorption
-
Agayan, R. R., Gittes, F., Kopelman, R. & Schmidt, C. F. Optical trapping near resonance absorption. Appl. Opt. 41, 2318-2327 (2002).
-
(2002)
Appl. Opt.
, vol.41
, pp. 2318-2327
-
-
Agayan, R.R.1
Gittes, F.2
Kopelman, R.3
Schmidt, C.F.4
-
177
-
-
62549122152
-
The reciprocal coordination and mechanics of molecular motors in living cells
-
Laib, J. A., Marin, J. A., Bloodgood, R. A. & Guilford, W. H. The reciprocal coordination and mechanics of molecular motors in living cells. Proc. Natl Acad. Sci. USA 106, 3190-3195 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 3190-3195
-
-
Laib, J.A.1
Marin, J.A.2
Bloodgood, R.A.3
Guilford, W.H.4
-
178
-
-
67650489044
-
High-resolution probing of cellular force transmission
-
Mizuno, D., Bacabac, R., Tardin, C., Head, D. & Schmidt, C. F. High-resolution probing of cellular force transmission. Phys. Rev. Lett. 102, 168102 (2009).
-
(2009)
Phys. Rev. Lett.
, vol.102
, pp. 168102
-
-
Mizuno, D.1
Bacabac, R.2
Tardin, C.3
Head, D.4
Schmidt, C.F.5
-
179
-
-
33846625096
-
Nonequilibrium mechanics of active cytoskeletal networks
-
Mizuno, D., Tardin, C., Schmidt, C. F. & MacKintosh, F. C. Nonequilibrium mechanics of active cytoskeletal networks. Science 315, 370-373 (2007).
-
(2007)
Science
, vol.315
, pp. 370-373
-
-
Mizuno, D.1
Tardin, C.2
Schmidt, C.F.3
MacKintosh, F.C.4
-
180
-
-
0000534160
-
Position measurement with a resolution and noise-limited instrument
-
Bobroff, N. Position measurement with a resolution and noise-limited instrument. Rev. Sci. Instr. 57, 1152-1157 (1986).
-
(1986)
Rev. Sci. Instr.
, vol.57
, pp. 1152-1157
-
-
Bobroff, N.1
-
181
-
-
0036231415
-
Precise nanometer localization analysis for individual fluorescent probes
-
A fundamental discussion of attainable accuracy in localizing single fluorescent molecules in a microscope
-
Thompson, R. E., Larson, D. R. & Webb, W. W. Precise nanometer localization analysis for individual fluorescent probes. Biophys. J. 82, 2775-2783 (2002). A fundamental discussion of attainable accuracy in localizing single fluorescent molecules in a microscope.
-
(2002)
Biophys. J.
, vol.82
, pp. 2775-2783
-
-
Thompson, R.E.1
Larson, D.R.2
Webb, W.W.3
-
182
-
-
49549091342
-
Protein modification for single molecule fluorescence microscopy
-
Dillingham, M. S. & Wallace, M. I. Protein modification for single molecule fluorescence microscopy. Org. Biomol. Chem. 6, 3031-3037 (2008).
-
(2008)
Org. Biomol. Chem.
, vol.6
, pp. 3031-3037
-
-
Dillingham, M.S.1
Wallace, M.I.2
-
183
-
-
33846499787
-
Characterization and application of single fluorescent nanodiamonds as cellular biomarkers
-
Fu, C. C. et al. Characterization and application of single fluorescent nanodiamonds as cellular biomarkers. Proc. Natl Acad. Sci. USA 104, 727-732 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 727-732
-
-
Fu, C.C.1
-
184
-
-
68649095245
-
Fluorescence and spin properties of defects in single digit nanodiamonds
-
Tisler, J. et al. Fluorescence and spin properties of defects in single digit nanodiamonds. ACS Nano 3, 1959-1965 (2009).
-
(2009)
ACS Nano
, vol.3
, pp. 1959-1965
-
-
Tisler, J.1
-
185
-
-
0037147175
-
Structure-assigned optical spectra of single-walled carbon nanotubes
-
Bachilo, S. M. et al. Structure-assigned optical spectra of single-walled carbon nanotubes. Science 298, 2361-2366 (2002).
-
(2002)
Science
, vol.298
, pp. 2361-2366
-
-
Bachilo, S.M.1
-
186
-
-
0343415156
-
The way things move: Looking under the hood of molecular motor proteins
-
Vale, R. D. & Milligan, R. A. The way things move: looking under the hood of molecular motor proteins. Science 288, 88-95 (2000).
-
(2000)
Science
, vol.288
, pp. 88-95
-
-
Vale, R.D.1
Milligan, R.A.2
-
187
-
-
28844444610
-
High-speed atomic force microscopy for capturing dynamic behavior of protein molecules at work
-
Ando, T. et al. High-speed atomic force microscopy for capturing dynamic behavior of protein molecules at work. e-J. Surf. Sci. Nanotech. 3, 384-392 (2005).
-
(2005)
e-J. Surf. Sci. Nanotech.
, vol.3
, pp. 384-392
-
-
Ando, T.1
|