Allosteric inhibition of kinesin-5 modulates its processive directional motility

Nature Chemical Biology

Volumn 2, Issue 9, 2006, Pages 480-485

  Kwok, Benjamin H ^a   Kapitein, Lukas C ^b   Kim, Jeffrey H ^a   Peterman, Erwin J G ^b   Schmidt, Christoph F ^b,c   Kapoor, Tarun M ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; EG5 PROTEIN; ENZYME INHIBITOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; KINESIN; KINESIN 5; KINESIN 5 INHIBITOR; MONASTROL; TUBULIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING COMPETITION; CELL DIVISION; CELL MOTILITY; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; ENZYME INHIBITION; EUKARYOTIC CELL; FLUORESCENCE; HYDROLYSIS; MICROTUBULE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; UNSPECIFIED SIDE EFFECT; VERTEBRATE;

EUKARYOTA; VERTEBRATA;

EID: 33747624954     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio812     Document Type: Article

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