Myosin I can act as a molecular force sensor

Science

Volumn 321, Issue 5885, 2008, Pages 133-136

  Laakso, Joseph M ^a   Lewis, John H ^a   Shuman, Henry ^a   Ostap, E Michael ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; MYOSIN I;

AUDITORY CUE; KINETICS; MEMBRANE; MOLECULAR ANALYSIS; SENSITIVITY ANALYSIS;

ARTICLE; AUDITORY STIMULATION; CELL SHAPE; EUKARYOTIC CELL; PRIORITY JOURNAL; PROTEIN INTERACTION;

ACTINS; ACTOMYOSIN; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; ANIMALS; BIOPHYSICS; KINETICS; LIKELIHOOD FUNCTIONS; MODELS, BIOLOGICAL; MOLECULAR MOTOR PROTEINS; MONTE CARLO METHOD; MYOSIN TYPE I; OPTICAL TWEEZERS; PROTEIN STRUCTURE, TERTIARY; RABBITS; STRESS, MECHANICAL;

EID: 46849089895     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1159419     Document Type: Article

References (25)

1. J. S. Berg, B. C. Powell, R. E. Cheney, Mol. Biol. Cell 12, 780 (2001).
2. J. R. Holt et al., Cell 108, 371 (2002).
3. C. Batters, M. I. Wallace, L. M. Coluccio, J. E. Molloy, Philos. Trans. R. Soc. London Ser. B 359, 1895 (2004).
4. P. G. Gillespie, J. L. Cyr, Annu. Rev. Physiol. 66, 521 (2004).
5. A. Bose et al., Nature 420, 821 (2002).
6. R. E. McConnell, M. J. Tyska, J. Cell Biol. 177, 671 (2007).
7. D. E. Hokanson, J. M. Laakso, T. Lin, D. Sept, E. M. Ostap, Mol. Biol. Cell 17, 4856 (2006).
8. L. Salas-Cortes et al., J. Cell Sci. 118, 4823 (2005).
9. M. A. Geeves, C. Perreault-Micale, L. M. Coluccio, J. Biol. Chem. 275, 21624 (2000).
10. C. Veigel et al., Nature 398, 530 (1999).
11. J. D. Jontes, E. M. Wilson-Kubalek, R. A. Milligan, Nature 378, 751 (1995).
12. R. F. Siemankowski, M. O. Wiseman, H. D. White, Proc. Natl. Acad. Sci. U.S.A. 82, 658 (1985).
13. J. H. Lewis, T. Lin, D. E. Hokanson, E. M. Ostap, Biochemistry 45, 11589 (2006).
14. C. Veigel, S. Schmitz, F. Wang, J. R. Sellers, Nat. Cell Biol. 7, 861 (2005).
15. J. T. Finer, R. M. Simmons, J. A. Spudich, Nature 368, 113 (1994).
16. T. Lin, N. Tang, E. M. Ostap, J. Biol. Chem. 280, 41562 (2005).
17. See methods in supporting information on Science Online.
18. C. Veigel, J. E. Molloy, S. Schmitz, J. Kendrick-Jones, Nat. Cell Biol. 5, 980 (2003).
19. D. M. Warshaw et al., J. Biol. Chem. 275, 37167 (2000).
20. C. Ruppert, R. Kroschewski, M. Bahler, J. Cell Biol. 120, 1393 (1993).
21. Y. Takagi, E. E. Homsher, Y. E. Goldman, H. Shuman, Biophys. J. 90, 1295 (2006).
22. G. I. Bell, Science 200, 618 (1978).
23. D. Altman, H. L. Sweeney, J. A. Spudich, Cell 116, 737 (2004).
24. D. Tsygankov, M. E. Fisher, Proc. Natl. Acad. Sci. U.S.A. 104, 19321 (2007).
25. We thank T. Lin for technical assistance and Y. E. Goldman for helpful discussions. Supported by NIH grants AR051174 (H.S. and E.M.O.) and GM057247 (E.M.O.).