Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid

Science

Volumn 314, Issue 5801, 2006, Pages 1001-1004

  Woodside, Michael T ^a,b   Anthony, Peter C ^b   Behnke Parks, William M ^b   Larizadeh, Kevan ^b   Herschlag, Daniel ^b   Block, Steven M ^b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FREE ENERGY; MACROMOLECULES; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS;

ENERGY BARRIERS; ENERGY LANDSCAPES; HAIRPIN SEQUENCES; OPTICAL FORCE CLAMPS;

NUCLEIC ACIDS;

DNA;

DNA; GENETIC STRUCTURE; MODEL;

ARTICLE; BASE MISPAIRING; BASE PAIRING; DNA DETERMINATION; DNA SEQUENCE; DNA STRUCTURE; ENERGY; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

BASE PAIR MISMATCH; BASE PAIRING; DNA; MODELS, CHEMICAL; NUCLEIC ACID CONFORMATION; THERMODYNAMICS;

EID: 33750970551     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1133601     Document Type: Article

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28. We thank members of the Block lab and the Ribozyme Folding Project for helpful discussions and manuscript comments. Supported by NIH P01-GM066275.