Interhead distance measurements in myosin VI via SHRImP support a simplified hand-over-hand model

Biophysical Journal

Volumn 89, Issue 1, 2005, Pages 413-417

  Balci, Hamza ^a   Ha, Taekjip ^a   Sweeney, H Lee ^b   Selvin, Paul R ^a,c  

^a University of Illinois at Urbana Champaign   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; MYOSIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN ADENOSINE TRIPHOSPHATASE VI; MYOSIN VI; UNCLASSIFIED DRUG;

ARTICLE; BLEACHING; CRYOELECTRON MICROSCOPY; HAND OVER HAND MODEL; IMAGING; MEASUREMENT; MODEL; MOLECULAR DYNAMICS; PROTEIN STRUCTURE; SINGLE MOLECULE HIGH RESOLUTION IMAGING WITH PHOTOBLEACHING; TECHNIQUE;

EID: 23244444140     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.105.060608     Document Type: Article

References (27)

1. Berg, J. S., B. C. Powell, and R. E. Cheney. 2001. A millennial myosin census. Mol. Biol. Cell. 12:780-794.
2. Kellerman, K. A., and K. G. Miller. 1992. An unconventional myosin heavy chain gene from Drosophila melanogaster. J. Cell Biol. 119:823-834.
3. Hasson, T., and M. S. Mooseker. 1994. Porcine myosin VI: characterization of a new mammalian unconventional myosin. J. Cell Biol. 127:425-440.
4. Avraham, K. B., T. Hasson, T. Sobe, B. Balsara, J. R. Testa, A. B. Skvorak, C. C. Morton, N. G. Copeland, and N. A. Jenkins. 1997. Characterization of unconventional MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice. Hum. Mol. Genet. 6:1225-1231.
5. Avraham, K. B., T. Hasson, K. P. Steel, D. M. Kingsley, L. B. Russell, M. S. Mooseker, N. G. Copeland, and N. A. Jenkins. 1995. The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nat. Genet. 11:369-375.
6. Hasson, T., P. G. Gillespie, J. A. Garcia, R. B. MacDonald, Y. Zhao, A. G. Yee, M. S. Mooseker, and D. P. Corey. 1997. Unconventional myosins in inner-ear sensory epithelia. J. Cell Biol. 137:1287-1307.
7. Wells, A. L., A. W. Lin, L. Q. Chen, D. Safer, S. M. Cain, T. Hasson, B. O. Carragher, R. A. Milligan, and H. L. Sweeney. 1999. Myosin VI is an actin-based motor that moves backwards. Nature. 401:505-508.
8. Buss, F., S. D. Arden, M. Lindsay, J. P. Luzio, and J. Kendrick-Jones. 2001. Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis. EMBO J. 20:3676-3684.
9. Aschenbrenner, L., T. Lee, and T. Hasson. 2003. Myo6 facilitates the translocation of endocytic vesicles from cell peripheries. Mol. Biol. Cell. 14:2728-2743.
10. Lister, I., S. Schmitz, M. Walker, J. Trinick, F. Buss, C. Veigel, and J. Kendrick-Jones. 2004. A monomeric myosin VI with a large working stroke. EMBO J. 23:1729-1738.
11. Rock, R. S., S. E. Rice, A. L. Wells, T. J. Purcell, J. A. Spudich, and H. L. Sweeney. 2001. Myosin VI is a processive motor with a large step size. Proc. Natl. Acad. Sci. USA. 98:13655-13659.
12. Nishikawa, S., K. Homma, Y. Komori, M. Iwaki, T. Wazawa, A. Hikikoshi Iwane, J. Saito, R. Ikebe, E. Katayama, T. Yanagida, and M. Ikebe. 2002. Class VI myosin moves processively along actin filaments backward with large steps. Biochem. Biophys. Res. Commun. 290:311-317.
13. Yildiz, A., H. Park, D. Safer, Z. Yang, L. Q. Chen, P. R. Selvin, and H. L. Sweeney. 2004. Myosin VI steps via a hand-over-hand mechanism with its lever arm undergoing fluctuations when attached to actin. J. Biol. Chem. 279:37223-37226.
14. Okten, Z., L. S. Churchman, R. S. Rock, and J. A. Spudich. 2004. Myosin VI walks hand-over-hand along actin. Nat. Struct. Mol. Biol. 11:884-887.
15. Altman, D., H. L. Sweeney, and J. A. Spudich. 2004. The mechanism of myosin VI translocation and its load-induced anchoring. Cell. 116:737-749.
16. Mehta, A. D., R. S. Rock, M. Rief, J. A. Spudich, M. S. Mooseker, and R. E. Cheney. 1999. Myosin V is a processive actin-based motor. Nature. 400:590-593.
17. Yildiz, A., M. Tomishige, R. D. Vale, and P. R. Selvin. 2004. Kinesin walks hand-over-hand. Science. 303:676-678.
18. Yildiz, A., J. N. Forkey, S. A. McKinney, T. Ha, Y. E. Goldman, and P. R. Selvin. 2003. Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization. Science. 300:2061-2065.
19. Sakamoto, T., I. Amitani, E. Yokota, and T. Ando. 2000. Direct observation of processive movement by individual myosin V molecules. Biochem. Biophys. Res. Commun. 272:586-590.
20. Purcell, T. J., C. Morris, J. A. Spudich, and H. L. Sweeney. 2002. Role of the lever arm in the processive stepping of myosin V. Proc. Natl. Acad. Sci. USA. 99:14159-14164.
21. Mehta, A. 2001. Myosin learns to walk. J. Cell Sci. 114:1981-1998.
22. Veigel, C., F. Wang, M. L. Bartoo, J. R. Sellers, and J. E. Molloy. 2002. The gated gait of the processive molecular motor, myosin V. Nat. Cell Biol. 4:59-65.
23. Forkey, J. N., M. E. Quinlan, M. A. Shaw, J. E. Corrie, and Y. E. Goldman. 2003. Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization. Nature. 422:399-404.
24. Warshaw, D. M., G. Kennedy, S. Work, E. Krementsova, S. Beck, and K. Trybus. 2005. Differential labeling of myosin V heads with quantum dots allows direct visualization of hand-over-hand processivity. Biophys. J. 88:L30-L32.
25. Rock, R. S., B. Ramamurthy, A. R. Dunn, S. Beccafico, B. R. Rami, C. Morris, B. J. Spink, C. Franzini-Armstrong, J. A. Spudich, and H. L. Sweeney. 2005. A flexible domain is essential for the large step size and processivity of myosin VI. Mol. Cell. 17:603-609.
26. Gordon, M. P., T. Ha, and P. R. Selvin. 2004. Single-molecule high-resolution imaging with photobleaching. Proc. Natl. Acad. Sci. USA. 101:6462-6465.
27. Qu, X., D. Wu, L. Mets, and N. F. Scherer. 2004. Nanometer-localized multiple single-molecule fluorescence microscopy. Proc. Natl. Acad. Sci. USA. 101:11298-11303.