Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions

Expert Review of Proteomics

Volumn 8, Issue 1, 2011, Pages 43-59

  Chalmers, Michael J ^a   Busby, Scott A ^a   Pascal, Bruce D ^a   West, Graham M ^a   Griffin, Patrick R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

GPCR; HDX; ligand; MS; nuclear receptor; screening

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ALFACIDOL; CALCITRIOL; CALCITRIOL DERIVATIVE; CELL NUCLEUS RECEPTOR; DEXAMETHASONE; DOCETAXEL; ELDECALCITOL; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; FARNESOID X RECEPTOR; FATTY ACID; G PROTEIN COUPLED RECEPTOR; HORMONE RECEPTOR; LAULIMALIDE; LIVER X RECEPTOR; MIFEPRISTONE; N (2 BENZOYLPHENYL) O [2 (METHYL 2 PYRIDINYLAMINO)ETHYL]TYROSINE; OXYSTEROL; PACLITAXEL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PROTEIN KINASE; RETINOID X RECEPTOR; ROSIGLITAZONE; STEROID RECEPTOR; THYROID HORMONE RECEPTOR; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ANTIGEN ANTIBODY REACTION; BINDING SITE; DATA ANALYSIS; DEUTERIUM HYDROGEN EXCHANGE; INFORMATION PROCESSING; LIGAND BINDING; MASS SPECTROMETRY; PROTEIN DOMAIN; PROTEIN INTERACTION; REVIEW;

ANIMALS; DEUTERIUM EXCHANGE MEASUREMENT; HORMONES; HUMANS; HYDROGEN; LIGANDS; MASS SPECTROMETRY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 79951907062     PISSN: 14789450     EISSN: 17448387     Source Type: Journal    
DOI: 10.1586/epr.10.109     Document Type: Review

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