Dynamics of the β2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange

Analytical Chemistry

Volumn 82, Issue 3, 2010, Pages 1100-1108

  Zhang, Xi ^a   Chien, Ellen Y T ^b   Chalmers, Michael J ^a   Pascal, Bruce D ^a   Gatchalian, Jovylyn ^b   Stevens, Raymond C ^b   Griffin, Patrick R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; DEUTERIUM EXCHANGE; DYNAMIC REGION; EXPERIMENTAL CONDITIONS; G-PROTEIN COUPLED RECEPTORS; HYDROGEN-DEUTERIUM EXCHANGE; MEMBRANE PROTEINS; STABILIZING LIGANDS; STRUCTURE DETERMINATION; THERMAL PARAMETERS;

AMIDES; CHEMICAL MODIFICATION; DEUTERIUM; LIGANDS; MASS SPECTROMETRY; PROTEINS;

CRYSTAL STRUCTURE;

BETA 2 ADRENERGIC RECEPTOR; CARAZOLOL; DEUTERIUM; HYDROGEN; PROPANOLAMINE DERIVATIVE;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; DRUG POTENTIATION; HUMAN; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; DEUTERIUM; DEUTERIUM EXCHANGE MEASUREMENT; HUMANS; HYDROGEN; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PROPANOLAMINES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, BETA-2;

EID: 76149083241     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac902484p     Document Type: Article

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