Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by hydrogen exchange mass spectrometry

Analytical Chemistry

Volumn 82, Issue 13, 2010, Pages 5415-5419

  Hebling, Christine M ^a   Morgan, Christopher R ^b   Stafford, Darrel W ^c   Jorgenson, James W ^a   Rand, Kasper D ^b   Engen, John R ^b  

^a University of North Carolina at Chapel Hill   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL PARAMETERS; AQUEOUS ENVIRONMENT; CHROMATOGRAPHIC SEPARATIONS; CONFORMATIONAL ANALYSIS; HYDROGEN EXCHANGE; IN-VIVO; MEMBRANE PROTEIN STRUCTURES; MEMBRANE PROTEINS; MODEL MEMBRANES; MONODISPERSE; NANODISCS; NATIVE CONFORMATION; NATIVE ENVIRONMENT; PHOSPHOLIPID BILAYER; SAMPLE HANDLING; TRANS-MEMBRANE PROTEINS;

BIOLOGICAL MEMBRANES; CONFORMATIONS; DEUTERIUM; HEAVY WATER; LIPID BILAYERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEMBRANES; PHOSPHOLIPIDS;

PROTEINS;

DEUTERIUM OXIDE; GLUTAMYL CARBOXYLASE; LIGASE; MEMBRANE PROTEIN; NANOMATERIAL; PHOSPHOLIPID; LIPID BILAYER;

ARTICLE; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; LIPID BILAYER; MASS SPECTROMETRY; METHODOLOGY; PH; PROCEDURES;

CARBON-CARBON LIGASES; DEUTERIUM EXCHANGE MEASUREMENT; DEUTERIUM OXIDE; HYDROGEN-ION CONCENTRATION; LIPID BILAYERS; MASS SPECTROMETRY; MEMBRANE PROTEINS; NANOSTRUCTURES; PHOSPHOLIPIDS;

EID: 77954193701     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac100962c     Document Type: Article

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