SCOPUS 정보 검색 플랫폼

Volumn 84, Issue SUPPL. 37, 2001, Pages 89-98

High resolution, high-throughput amide Deuterium Exchange-Mass Spectrometry (DXMS) determination of protein binding site structure and dynamics: Utility in pharmaceutical design

(2) Woods Jr , Virgil L a Hamuro, Yoshitomo a

a UNIVERSITY OF CALIFORNIA SAN DIEGO (United States)

Author keywords

Drug discovery combinatorial chemistry; Euterium exchange; Hydrogen exchange; Mass spectrometry; Protein dynamics; Protein function; Protein structure; Proteomics

Indexed keywords

AMIDE; DEUTERIUM; HYDROGEN; PROTEIN; DISULFIDE; PEPTIDE HYDROLASE; PROTEOME;

BINDING SITE; COMBINATORIAL CHEMISTRY; CONFERENCE PAPER; DRUG DESIGN; DRUG RESEARCH; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN STRUCTURE; RECEPTOR BINDING; THERMODYNAMICS; AFFINITY CHROMATOGRAPHY; ARTICLE; AUTOMATION; CHEMISTRY; FORECASTING; METABOLISM; METHODOLOGY; OXIDATION REDUCTION REACTION; PHARMACEUTICS; PROTEIN CONFORMATION;

AMIDES; AUTOMATION; BINDING SITES; CHROMATOGRAPHY, AFFINITY; DEUTERIUM; DISULFIDES; DRUG DESIGN; FORECASTING; MASS SPECTROMETRY; OXIDATION-REDUCTION; PEPTIDE HYDROLASES; PROTEIN CONFORMATION; PROTEOME; TECHNOLOGY, PHARMACEUTICAL; THERMODYNAMICS;

EID: 0035753065 PISSN: 07302312 EISSN: None Source Type: Journal
DOI: 10.1002/jcb.10069 Document Type: Conference Paper

Times cited : (125)

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