Analysis of subsecond protein dynamics by amide hydrogen exchange and mass spectrometry using a quenched-flow setup

Protein Science

Volumn 14, Issue 3, 2005, Pages 626-632

  Rist, Wolfgang ^a,c   Rodriguez, Fernanda ^a   Jørgensen, Thomas J D ^b   Mayer, Matthias P ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Amide hydrogen exchange; Mass spectrometry; Protein conformation; Protein folding; Quenched flow

Indexed keywords

BACTERIAL PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR 1; PROTEINASE; RNA POLYMERASE; SIGMA FACTOR;

ALLOSTERISM; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ESCHERICHIA COLI; ION EXCHANGE; MASS SPECTROMETRY; MOLECULAR DYNAMICS; NONHUMAN; NONPHOTOCHEMICAL QUENCHING; PIPETTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; REPRODUCIBILITY;

CHEMISTRY, ANALYTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESCHERICHIA COLI; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SIGMA FACTOR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 14144253195     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.041098305     Document Type: Article

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