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Volumn 24, Issue 6, 2010, Pages 359-377

Systemic and mucosal delivery of drugs within polymeric microparticles produced by spray drying

Author keywords

drug carriers; drug delivery systems; microparticles

Indexed keywords

ALGINIC ACID; AMIOCA; AMPICILLIN; ANTIBIOTIC AGENT; ASCORBIC ACID; BECLOMETASONE DIPROPIONATE; BETAMETHASONE; BUDESONIDE; CARBOMER; CARBOPOL 974P; CHITOSAN; DICLOFENAC; DIFLUNISAL; EUDRAGIT; EUDRAGIT RS; EUDRAGIT RS 30D; FLUCONAZOLE; GELATIN; HEPARIN; HONOKIOL; HYDROCORTISONE; HYDROCORTISONE ACETATE; KETOPROFEN; METHACRYLIC ACID DERIVATIVE; MOXIFLOXACIN; PANTOPRAZOLE; PARACETAMOL; PIROXICAM; POLYESTER; POLYMER; POLYMYXIN B; TERBUTALINE SULFATE; THEOPHYLLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VACCINE;

EID: 78049523942     PISSN: 11738804     EISSN: 1179190X     Source Type: Journal    
DOI: 10.2165/11539070-000000000-00000     Document Type: Review
Times cited : (34)

References (164)
  • 1
    • 0036155431 scopus 로고    scopus 로고
    • Protein immobilization in crosslinked alginate microparticles
    • Jan-Feb
    • Coppi G, Iannuccelli V, Leo E, et al. Protein immobilization in crosslinked alginate microparticles. J Microencapsul 2002 Jan-Feb; 19 (1): 37-44
    • (2002) J Microencapsul , vol.19 , Issue.1 , pp. 37-44
    • Coppi, G.1    Iannuccelli, V.2    Leo, E.3
  • 2
    • 33847394433 scopus 로고    scopus 로고
    • Topical iodine facilitates transdermal delivery of insulin
    • Apr
    • Sintov AC, Wormser U. Topical iodine facilitates transdermal delivery of insulin. J Control Release 2007 Apr; 118 (2): 185-8
    • (2007) J Control Release , vol.118 , Issue.2 , pp. 185-8
    • Sintov, A.C.1    Wormser, U.2
  • 3
    • 33344477288 scopus 로고    scopus 로고
    • Influence of deposition and spray pattern of nasal powders on insulin bioavailability
    • Pringels E, Callens C, Vervaet C, et al. Influence of deposition and spray pattern of nasal powders on insulin bioavailability. Int J Pharm 2006; 310 (1-2): 1-7
    • (2006) Int J Pharm , vol.310 , Issue.1-2 , pp. 1-7
    • Pringels, E.1    Callens, C.2    Vervaet, C.3
  • 4
    • 0035806263 scopus 로고    scopus 로고
    • Effect of additives on insulin absorption from intratracheally administered dry powders in rats
    • Jun 4
    • Todo H, Okamoto H, Iida K, et al. Effect of additives on insulin absorption from intratracheally administered dry powders in rats. Int J Pharm 2001 Jun 4; 220 (1-2): 101-10
    • (2001) Int J Pharm , vol.220 , Issue.1-2 , pp. 101-10
    • Todo, H.1    Okamoto, H.2    Iida, K.3
  • 5
    • 0034607427 scopus 로고    scopus 로고
    • In vivo effects of highly purified docosahexaenoic acid on rectal insulin absorption
    • Apr 5
    • Onuki Y, Morishita M, Takayama K, et al. In vivo effects of highly purified docosahexaenoic acid on rectal insulin absorption. Int J Pharm 2000 Apr 5; 198 (2): 147-56
    • (2000) Int J Pharm , vol.198 , Issue.2 , pp. 147-56
    • Onuki, Y.1    Morishita, M.2    Takayama, K.3
  • 6
    • 33846543799 scopus 로고    scopus 로고
    • Oral delivery of insulin associated to polymeric nanoparticles in diabetic rats
    • Feb 12;
    • Damge C, Maincent P, Ubrich N. Oral delivery of insulin associated to polymeric nanoparticles in diabetic rats. J Control Release 2007 Feb 12; 117 (2): 163-70
    • (2007) J Control Release , vol.117 , Issue.2 , pp. 163-70
    • Damge, C.1    Maincent, P.2    Ubrich, N.3
  • 7
    • 15544362279 scopus 로고    scopus 로고
    • Polymeric particlesto improve oral bioavailability of peptide drugs
    • Delie F,Blanco-Prieto MJ. Polymeric particlesto improve oral bioavailability of peptide drugs. Molecules 2005; 10: 65-80
    • (2005) Molecules , vol.10 , pp. 65-80
    • Delie, F.1    Blanco-Prieto, M.J.2
  • 8
    • 33748752402 scopus 로고    scopus 로고
    • Is the oral route possible for peptide and protein drug delivery?
    • Oct
    • Morishita M, Peppas NA. Is the oral route possible for peptide and protein drug delivery? Drug Discov Today 2006 Oct; 11 (19-20): 905-10
    • (2006) Drug Discov Today , vol.11 , Issue.19-20 , pp. 905-10
    • Morishita, M.1    Peppas, N.A.2
  • 9
    • 22244488749 scopus 로고    scopus 로고
    • Oral delivery of peptide drugs: Barriers and developments
    • Hamman JH, Enslin GM, Kotze AF. Oral delivery of peptide drugs: barriers and developments. BioDrugs 2005; 19 (3): 165-77
    • (2005) BioDrugs , vol.19 , Issue.3 , pp. 165-77
    • Hamman, J.H.1    Enslin, G.M.2    Kotze, A.F.3
  • 10
    • 33645034817 scopus 로고    scopus 로고
    • Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles
    • Mar
    • Pinto Reis C, Neufeld RJ, Ribeiro AJ, et al. Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine 2006 Mar; 2 (1): 8-21
    • (2006) Nanomedicine , vol.2 , Issue.1 , pp. 8-21
    • Pinto Reis, C.1    Neufeld, R.J.2    Ribeiro, A.J.3
  • 11
    • 18144385104 scopus 로고    scopus 로고
    • Novel sustained release microspheres for pulmonary drug delivery
    • May 5
    • Cook RO, Pannu RK, Kellaway IW. Novel sustained release microspheres for pulmonary drug delivery. J Control Release 2005 May 5; 104 (1): 79-90
    • (2005) J Control Release , vol.104 , Issue.1 , pp. 79-90
    • Cook, R.O.1    Pannu, R.K.2    Kellaway, I.W.3
  • 12
    • 0035966497 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticles as drug delivery devices
    • Jan 29
    • Soppimath KS, Aminabhavi TM, Kulkarni AR, et al. Biodegradable polymeric nanoparticles as drug delivery devices. J Control Release 2001 Jan 29; 70 (1-2): 1-20
    • (2001) J Control Release , vol.70 , Issue.1-2 , pp. 1-20
    • Soppimath, K.S.1    Aminabhavi, T.M.2    Kulkarni, A.R.3
  • 13
    • 33751253462 scopus 로고    scopus 로고
    • Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
    • des Rieux A, Fievez V, Garinot M, et al Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach. J Control Release 2006; 116(1): 1-27
    • (2006) J Control Release , vol.116 , Issue.1 , pp. 1-27
    • Des Rieux, A.1    Fievez, V.2    Garinot, M.3
  • 14
    • 34547592146 scopus 로고    scopus 로고
    • Of proteins in biodegradable polymeric microparticles using electrospray in the Taylor cone-jet mode
    • CH. Encapsulation Aug 1
    • Xie J, Wang CH. Encapsulation of proteins in biodegradable polymeric microparticles using electrospray in the Taylor cone-jet mode. Biotechnol Bioeng 2007 Aug 1; 97 (5): 1278-90
    • (2007) Biotechnol Bioeng , vol.97 , Issue.5 , pp. 1278-90
    • Xie, J.1    Wang, C.H.2
  • 15
    • 0032121878 scopus 로고    scopus 로고
    • Microencapsulation by spray-drying
    • Re MI. Microencapsulation by spray-drying. Drying Technol 1998; 16 (16): 1195-36
    • (1998) Drying Technol , vol.16 , Issue.16 , pp. 1195-36
    • Re, M.I.1
  • 16
    • 0142184041 scopus 로고    scopus 로고
    • Chitosan: An attractive biocompatible polymer for microencapsulation
    • Oct
    • Peniche C, Arguelles-Monal W, Peniche H, et al. Chitosan: an attractive biocompatible polymer for microencapsulation. Macromol Biosci 2003 Oct; 3 (10): 511-20
    • (2003) Macromol Biosci , vol.3 , Issue.10 , pp. 511-20
    • Peniche, C.1    Arguelles-Monal, W.2    Peniche, H.3
  • 17
    • 33748784063 scopus 로고    scopus 로고
    • Targeted gene delivery with trisaccharide-substituted chitosan oligomers in vitro and after lung administration in vivo
    • Sep 28
    • Issa MM, Koping-Hoggard M, Tommeraas K, et al. Targeted gene delivery with trisaccharide-substituted chitosan oligomers in vitro and after lung administration in vivo. J Control Release 2006 Sep 28; 115 (1): 103-12
    • (2006) J Control Release , vol.115 , Issue.1 , pp. 103-12
    • Issa, M.M.1    Koping-Hoggard, M.2    Tommeraas, K.3
  • 18
    • 37849015123 scopus 로고    scopus 로고
    • Chitosan microspheres for intrapulmonary administration of moxifloxacin: Interaction with biomembrane models and in vitro permeation studies
    • Ventura CA, Tommasini S, Crupi E, et al. Chitosan microspheres for intrapulmonary administration of moxifloxacin: interaction with biomembrane models and in vitro permeation studies. EurJPharm Sci 2008;68(2): 235-44
    • (2008) EurJPharm Sci , vol.68 , Issue.2 , pp. 235-44
    • Ventura, C.A.1    Tommasini, S.2    Crupi, E.3
  • 19
    • 33846496876 scopus 로고    scopus 로고
    • Preparation of redispersible dry nanocapsules by means of spray-drying: Development and characterisation
    • Feb
    • Tewa-Tagne P, Briancon S, Fessi H. Preparation of redispersible dry nanocapsules by means of spray-drying: development and characterisation. Eur J Pharm Sci 2007 Feb; 30 (2): 124-35
    • (2007) Eur J Pharm Sci , vol.30 , Issue.2 , pp. 124-35
    • Tewa-Tagne, P.1    Briancon, S.2    Fessi, H.3
  • 20
    • 27744602789 scopus 로고    scopus 로고
    • Preparation of cross-linked chitosan microspheres by spray drying: Effect of cross-linking agent on the properties of spray dried microspheres
    • Jun
    • Desai KG, Park HJ. Preparation of cross-linked chitosan microspheres by spray drying: effect of cross-linking agent on the properties of spray dried microspheres. J Microencapsul 2005 Jun; 22 (4): 377-95
    • (2005) J Microencapsul , vol.22 , Issue.4 , pp. 377-95
    • Desai, K.G.1    Park, H.J.2
  • 21
    • 53649104479 scopus 로고    scopus 로고
    • Controlled release of drugs from multicomponent biomaterials
    • Nov
    • Zalfen AM, Nizet D, Jerome C, et al. Controlled release of drugs from multicomponent biomaterials. Acta Biomater 2008 Nov; 4 (6): 1788-96
    • (2008) Acta Biomater , vol.4 , Issue.6 , pp. 1788-96
    • Zalfen, A.M.1    Nizet, D.2    Jerome, C.3
  • 22
    • 1142309558 scopus 로고    scopus 로고
    • Lectin-mediated drug targeting: History and applications
    • Bies C, Lehr C, Woodley JF. Lectin-mediated drug targeting: history and applications. Adv Drug Deliv Rev 2004; 56 (4): 425-35
    • (2004) Adv Drug Deliv Rev , vol.56 , Issue.4 , pp. 425-35
    • Bies, C.1    Lehr, C.2    Woodley, J.F.3
  • 23
    • 33748795860 scopus 로고    scopus 로고
    • Microparticle-based technologies for vaccines
    • Sep
    • O'Hagan DT, Singh M, Ulmer JB. Microparticle-based technologies for vaccines. Methods 2006 Sep; 40 (1): 10-9
    • (2006) Methods , vol.40 , Issue.1 , pp. 10-9
    • O'Hagan, D.T.1    Singh, M.2    Ulmer, J.B.3
  • 24
    • 35349027729 scopus 로고    scopus 로고
    • Nanoparticles and microparticles as vaccine-delivery systems
    • Oct
    • Singh M, Chakrapani A, O'Hagan D. Nanoparticles and microparticles as vaccine-delivery systems. Expert Rev Vaccines 2007 Oct; 6 (5): 797-808
    • (2007) Expert Rev Vaccines , vol.6 , Issue.5 , pp. 797-808
    • Singh, M.1    Chakrapani, A.2    O'Hagan, D.3
  • 25
    • 60149111908 scopus 로고    scopus 로고
    • Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
    • Feb 27
    • Lai SK, Wang YY, Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv Drug Deliv Rev 2009 Feb 27; 61 (2): 158-71
    • (2009) Adv Drug Deliv Rev , vol.61 , Issue.2 , pp. 158-71
    • Lai, S.K.1    Wang, Y.Y.2    Hanes, J.3
  • 27
    • 0041334256 scopus 로고    scopus 로고
    • Control of the morphology of nanostructured particles prepared by the spray drying of a nanoparticle sol
    • Sep 15
    • Iskandar F, Gradon L, Okuyama K. Control of the morphology of nanostructured particles prepared by the spray drying of a nanoparticle sol. J Colloid Interface Sci 2003 Sep 15; 265 (2): 296-303
    • (2003) J Colloid Interface Sci , vol.265 , Issue.2 , pp. 296-303
    • Iskandar, F.1    Gradon, L.2    Okuyama, K.3
  • 28
    • 0031780284 scopus 로고    scopus 로고
    • Effect of spray drying and subsequent processing conditionson residual moisture content and physical/biochemical stability of protein inhalation powders
    • May
    • Maa YF, Nguyen PA, Andya JD, et al. Effect of spray drying and subsequent processing conditionson residual moisture content and physical/biochemical stability of protein inhalation powders. Pharm Res 1998 May; 15 (5): 768-75
    • (1998) Pharm Res , vol.15 , Issue.5 , pp. 768-75
    • Maa, Y.F.1    Nguyen, P.A.2    Andya, J.D.3
  • 29
    • 0031393964 scopus 로고    scopus 로고
    • The effect of operating and formulation variables on the morphology of spray-dried protein particles
    • Aug
    • Maa YF, Costantino HR, Nguyen PA, et al. The effect of operating and formulation variables on the morphology of spray-dried protein particles. Pharm Dev Technol 1997 Aug; 2 (3): 213-23
    • (1997) Pharm Dev Technol , vol.2 , Issue.3 , pp. 213-23
    • Maa, Y.F.1    Costantino, H.R.2    Nguyen, P.A.3
  • 30
    • 0034331056 scopus 로고    scopus 로고
    • Biopharmaceutical powders: Particle formation and formulation considerations
    • Nov
    • Maa YF, Prestrelski SJ. Biopharmaceutical powders: particle formation and formulation considerations. Curr Pharm Biotechnol 2000 Nov; 1 (3): 283-302
    • (2000) Curr Pharm Biotechnol , vol.1 , Issue.3 , pp. 283-302
    • Maa, Y.F.1    Prestrelski, S.J.2
  • 31
    • 0034712966 scopus 로고    scopus 로고
    • Parameters influencing the antigen release from spray-dried poly(DL-lactide) microparticles
    • Apr 25
    • Baras B, Benoit MA, Gillard J. Parameters influencing the antigen release from spray-dried poly(DL-lactide) microparticles. Int J Pharm 2000 Apr 25; 200 (1): 133-45
    • (2000) Int J Pharm , vol.200 , Issue.1 , pp. 133-45
    • Baras, B.1    Benoit, M.A.2    Gillard, J.3
  • 32
    • 0037295176 scopus 로고    scopus 로고
    • Preparation of nanoparticles via spray route
    • Okuyama K, Lenggoro IW. Preparation of nanoparticles via spray route. Chem Eng Sci 2003; 58: 537-47
    • (2003) Chem Eng Sci , vol.58 , pp. 537-47
    • Okuyama, K.1    Lenggoro, I.W.2
  • 33
    • 33645707180 scopus 로고    scopus 로고
    • Formulating drug delivery systems by spray drying
    • Re M. Formulating drug delivery systems by spray drying. Drying Technol 2006; 24 (4): 433-46
    • (2006) Drying Technol , vol.24 , Issue.4 , pp. 433-46
    • Re, M.1
  • 34
    • 33745547366 scopus 로고    scopus 로고
    • Review and current status of emulsion/dispersion technology using an internal gelation process for the design of alginate particles
    • May
    • Reis CP, Neufeld RJ, Vilela S, et al. Review and current status of emulsion/dispersion technology using an internal gelation process for the design of alginate particles. J Microencapsul 2006 May; 23 (3): 245-57
    • (2006) J Microencapsul , vol.23 , Issue.3 , pp. 245-57
    • Reis, C.P.1    Neufeld, R.J.2    Vilela, S.3
  • 35
    • 0033791218 scopus 로고    scopus 로고
    • Technological considerations related to the up-scaling of protein microencapsulation by spray-drying
    • Nov
    • Johansen P, Merkle HP, Gander B. Technological considerations related to the up-scaling of protein microencapsulation by spray-drying. Eur J Pharm Biopharm 2000 Nov; 50 (3): 413-7
    • (2000) Eur J Pharm Biopharm , vol.50 , Issue.3 , pp. 413-7
    • Johansen, P.1    Merkle, H.P.2    Gander, B.3
  • 36
    • 0034837639 scopus 로고    scopus 로고
    • Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres
    • Sep
    • Lam XM, Duenas ET, Cleland JL. Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres. J Pharm Sci 2001 Sep; 90 (9): 1356-65
    • (2001) J Pharm Sci , vol.90 , Issue.9 , pp. 1356-65
    • Lam, X.M.1    Duenas, E.T.2    Cleland, J.L.3
  • 37
    • 64649107435 scopus 로고    scopus 로고
    • Preparation and characterization of starch-poly-epsilon-caprolactone microparticles incorporating bioactive agents for drug delivery and tissue engineering applications
    • May
    • Balmayor ER, Tuzlakoglu K, Azevedo HS, et al. Preparation and characterization of starch-poly-epsilon-caprolactone microparticles incorporating bioactive agents for drug delivery and tissue engineering applications. Acta Biomater 2009 May; 5 (4): 1035-45
    • (2009) Acta Biomater , vol.5 , Issue.4 , pp. 1035-45
    • Balmayor, E.R.1    Tuzlakoglu, K.2    Azevedo, H.S.3
  • 38
    • 41349110165 scopus 로고    scopus 로고
    • Preparation, characterization and antibacterial activities of chitosan, N-trimethyl chitosan (TMC) and N-diethylmethyl chitosan (DEMC) nanoparticles loaded with insulin using both the ionotropic gelation and polyelectrolyte complexation methods
    • May 1
    • Sadeghi AM, Dorkoosh FA, Avadi MR, et al. Preparation, characterization and antibacterial activities of chitosan, N-trimethyl chitosan (TMC) and N-diethylmethyl chitosan (DEMC) nanoparticles loaded with insulin using both the ionotropic gelation and polyelectrolyte complexation methods. Int J Pharm 2008 May 1; 355 (1-2): 299-306
    • (2008) Int J Pharm , vol.355 , Issue.1-2 , pp. 299-306
    • Sadeghi, A.M.1    Dorkoosh, F.A.2    Avadi, M.R.3
  • 39
    • 67650806122 scopus 로고    scopus 로고
    • Particle characterization of poorly water-soluble drugs using a spray freeze drying technique
    • Jul
    • Kondo M, Niwa T, Okamoto H, et al. Particle characterization of poorly water-soluble drugs using a spray freeze drying technique. Chem Pharm Bull (Tokyo) 2009 Jul; 57 (7): 657-62
    • (2009) Chem Pharm Bull (Tokyo) , vol.57 , Issue.7 , pp. 657-62
    • Kondo, M.1    Niwa, T.2    Okamoto, H.3
  • 40
    • 54949117110 scopus 로고    scopus 로고
    • Quality by design: Spray drying of insulin intended for inhalation
    • Nov
    • Maltesen MJ, Bjerregaard S, Hovgaard L, et al. Quality by design: spray drying of insulin intended for inhalation. Eur J Pharm Biopharm 2008 Nov; 70 (3): 828-38
    • (2008) Eur J Pharm Biopharm , vol.70 , Issue.3 , pp. 828-38
    • Maltesen, M.J.1    Bjerregaard, S.2    Hovgaard, L.3
  • 41
    • 58149473078 scopus 로고    scopus 로고
    • Retained integrity of protein encapsulated in spray-dried chitosan microparticles
    • Mar
    • Kusonwiriyawong C, Pichayakorn W, Lipipun V, et al. Retained integrity of protein encapsulated in spray-dried chitosan microparticles. J Micro-encapsul 2009 Mar; 26 (2): 111-21
    • (2009) J Micro-encapsul , vol.26 , Issue.2 , pp. 111-21
    • Kusonwiriyawong, C.1    Pichayakorn, W.2    Lipipun, V.3
  • 42
    • 33750015976 scopus 로고    scopus 로고
    • Spray-dried microparticles containing polymeric nanocapsules: Formulation aspects, liquid phase interactions and particles characteristics
    • Tewa-Tagne P, Briançon S, Fessi H. Spray-dried microparticles containing polymeric nanocapsules: formulation aspects, liquid phase interactions and particles characteristics. Int J Pharm 2006; 325 (1-2): 63-74
    • (2006) Int J Pharm , vol.325 , Issue.1-2 , pp. 63-74
    • Tewa-Tagne, P.1    Briançon, S.2    Fessi, H.3
  • 43
    • 0031881636 scopus 로고    scopus 로고
    • PDLLA microspheres containing steroids: Spray-drying, o/w and w/o/w emulsifications as preparation methods
    • Mar-Apr
    • Giunchedi P, Alpar HO, Conte U. PDLLA microspheres containing steroids: spray-drying, o/w and w/o/w emulsifications as preparation methods. J Microencapsul 1998 Mar-Apr; 15 (2): 185-95
    • (1998) J Microencapsul , vol.15 , Issue.2 , pp. 185-95
    • Giunchedi, P.1    Alpar, H.O.2    Conte, U.3
  • 44
    • 77953662360 scopus 로고    scopus 로고
    • Optimization of experimental parameters for the production of LMWH-loaded polymeric microspheres
    • Feb 6
    • Motlekar N, Youan BB. Optimization of experimental parameters for the production of LMWH-loaded polymeric microspheres. Drug Des Devel Ther 2009 Feb 6; 2: 39-47
    • (2009) Drug des Devel Ther , vol.2 , pp. 39-47
    • Motlekar, N.1    Youan, B.B.2
  • 45
    • 0037093745 scopus 로고    scopus 로고
    • Spray-dryed bupivacaine-loaded microspheres: In vitro evaluation and biopharmaceutics of bupivacaine following brachial plexus administration in sheep
    • May 15
    • Le Corre P, Estebe JP, Clement R, et al. Spray-dryed bupivacaine-loaded microspheres: in vitro evaluation and biopharmaceutics of bupivacaine following brachial plexus administration in sheep. Int J Pharm 2002 May 15; 238 (1-2): 191-203
    • (2002) Int J Pharm , vol.238 , Issue.1-2 , pp. 191-203
    • Le Corre, P.1    Estebe, J.P.2    Clement, R.3
  • 46
    • 0030885012 scopus 로고    scopus 로고
    • Biodegradable microspheres for the intravitreal administration of acyclovir: In vitro/in vivo evaluation
    • Conti B, Bucolo C, Giannavola C, et al. Biodegradable microspheres for the intravitreal administration of acyclovir: in vitro/in vivo evaluation. Eur J Pharm Sci 1997; 5: 287-93
    • (1997) Eur J Pharm Sci , vol.5 , pp. 287-93
    • Conti, B.1    Bucolo, C.2    Giannavola, C.3
  • 47
    • 0032904287 scopus 로고    scopus 로고
    • Modulation of rifampicin release from spray-dried microspheres using combinations of poly-(DL-lactide)
    • May-Jun
    • Bain DF, Munday DL, Smith A. Modulation of rifampicin release from spray-dried microspheres using combinations of poly-(DL-lactide). J Microencapsul 1999 May-Jun; 16 (3): 369-85
    • (1999) J Microencapsul , vol.16 , Issue.3 , pp. 369-85
    • Bain, D.F.1    Munday, D.L.2    Smith, A.3
  • 48
    • 0033976485 scopus 로고    scopus 로고
    • Vaccine properties of antigens entrapped in microparticles produced by spray-drying technique and using various polyester polymers
    • Feb 14
    • Baras B, Benoit M, Poulain-Godefroy O, et al. Vaccine properties of antigens entrapped in microparticles produced by spray-drying technique and using various polyester polymers. Vaccine 2000 Feb 14; 18 (15): 1495-505
    • (2000) Vaccine , vol.18 , Issue.15 , pp. 1495-505
    • Baras, B.1    Benoit, M.2    Poulain-Godefroy, O.3
  • 49
    • 0028157782 scopus 로고
    • Piroxicam release from spray-dried biodegradable microspheres
    • Jan
    • Wagenaar BW, Muller BW. Piroxicam release from spray-dried biodegradable microspheres. Biomaterials 1994 Jan; 15 (1): 49-54
    • (1994) Biomaterials , vol.15 , Issue.1 , pp. 49-54
    • Wagenaar, B.W.1    Muller, B.W.2
  • 50
    • 0036658042 scopus 로고    scopus 로고
    • Effects of fabrication conditions on the characteristics of etanidazole spray-dried microspheres
    • Jul-Aug
    • Wang FJ, Wang CH. Effects of fabrication conditions on the characteristics of etanidazole spray-dried microspheres. J Microencapsul 2002 Jul-Aug; 19 (4): 495-510
    • (2002) J Microencapsul , vol.19 , Issue.4 , pp. 495-510
    • Wang, F.J.1    Wang, C.H.2
  • 51
    • 0032781744 scopus 로고    scopus 로고
    • Microencapsulation of erythromycin and clarithromycin using a spray-drying technique
    • Sep-Oct
    • Zgoulli S, Grek V, Barre G, et al. Microencapsulation of erythromycin and clarithromycin using a spray-drying technique. J Microencapsul 1999 Sep-Oct; 16 (5): 565-71
    • (1999) J Microencapsul , vol.16 , Issue.5 , pp. 565-71
    • Zgoulli, S.1    Grek, V.2    Barre, G.3
  • 52
    • 0031840056 scopus 로고    scopus 로고
    • Preparation and characterization of ampicillin loaded methylpyrrolidinone chitosan and chitosan microspheres
    • Jan-Feb
    • Giunchedi P, Genta I, Conti B, et al. Preparation and characterization of ampicillin loaded methylpyrrolidinone chitosan and chitosan microspheres. Biomaterials 1998 Jan-Feb; 19 (1-3): 157-61
    • (1998) Biomaterials , vol.19 , Issue.1-3 , pp. 157-61
    • Giunchedi, P.1    Genta, I.2    Conti, B.3
  • 53
    • 33744761444 scopus 로고    scopus 로고
    • Spray drying of biopharmaceuticals: Stability and process considerations
    • Ameri M, Yuh-Fun Maa. Spray drying of biopharmaceuticals: stability and process considerations. Drying Technol 2006; 24 (6): 763-8
    • (2006) Drying Technol , vol.24 , Issue.6 , pp. 763-8
    • Ameri, M.1    Yuh-Fun, Maa.2
  • 54
    • 0034768026 scopus 로고    scopus 로고
    • Spray-dried insulin particles retain biological activity in rapid in-vitro assay
    • Oct
    • Patel N, Craddock BL, Staniforth JN, et al. Spray-dried insulin particles retain biological activity in rapid in-vitro assay. J Pharm Pharmacol 2001 Oct; 53 (10): 1415-8
    • (2001) J Pharm Pharmacol , vol.53 , Issue.10 , pp. 1415-8
    • Patel, N.1    Craddock, B.L.2    Staniforth, J.N.3
  • 55
    • 33750804217 scopus 로고    scopus 로고
    • Particle engineering techniques for inhaled biopharmaceuticals
    • Oct 31
    • Shoyele SA, Cawthorne S. Particle engineering techniques for inhaled biopharmaceuticals. Adv Drug Deliv Rev 2006 Oct 31; 58 (9-10): 1009-29
    • (2006) Adv Drug Deliv Rev , vol.58 , Issue.9-10 , pp. 1009-29
    • Shoyele, S.A.1    Cawthorne, S.2
  • 56
    • 0037372407 scopus 로고    scopus 로고
    • Optimizing formulation factors in preparing chitosan microparticles by spray-drying method
    • Mar-Apr
    • Huang YC, Chiang CH, Yeh MK. Optimizing formulation factors in preparing chitosan microparticles by spray-drying method. J Microencapsul 2003 Mar-Apr; 20 (2): 247-60
    • (2003) J Microencapsul , vol.20 , Issue.2 , pp. 247-60
    • Huang, Y.C.1    Chiang, C.H.2    Yeh, M.K.3
  • 57
    • 0037148657 scopus 로고    scopus 로고
    • The effect of process variables on the degradation and physical properties of spray dried insulin intended for inhalation
    • Feb 21
    • Stahl K, Claesson M, Lilliehorn P, et al. The effect of process variables on the degradation and physical properties of spray dried insulin intended for inhalation. Int J Pharm 2002 Feb 21; 233 (1-2): 227-37
    • (2002) Int J Pharm , vol.233 , Issue.1-2 , pp. 227-37
    • Stahl, K.1    Claesson, M.2    Lilliehorn, P.3
  • 58
    • 42049094490 scopus 로고    scopus 로고
    • Pharmaceutical particle engineering via spray drying
    • May
    • Vehring R. Pharmaceutical particle engineering via spray drying. Pharm Res 2008 May; 25 (5): 999-1022
    • (2008) Pharm Res , vol.25 , Issue.5 , pp. 999-1022
    • Vehring, R.1
  • 59
    • 0025931678 scopus 로고
    • Preparation of coated particles using a spray drying process with an aqueous system
    • Wan LSC, Heng PWS, Chia CGH. Preparation of coated particles using a spray drying process with an aqueous system. Int J Pharm 1991; 77 (2-3): 183-91
    • (1991) Int J Pharm , vol.77 , Issue.2-3 , pp. 183-91
    • Lsc, W.1    Pws, H.2    Chia, C.G.H.3
  • 60
    • 0034255285 scopus 로고    scopus 로고
    • Development of spray-dried acetaminophen microparticles using experimental designs
    • Aug 10
    • Billon A, Bataille B, Cassanas G, et al. Development of spray-dried acetaminophen microparticles using experimental designs. Int J Pharm 2000 Aug 10; 203 (1-2): 159-68
    • (2000) Int J Pharm , vol.203 , Issue.1-2 , pp. 159-68
    • Billon, A.1    Bataille, B.2    Cassanas, G.3
  • 61
    • 33751334375 scopus 로고    scopus 로고
    • Formulation and testing of vancomycin loaded albumin microspheres prepared by spray-drying
    • Sep
    • Nettey H, Haswani D, Oettinger CW, et al. Formulation and testing of vancomycin loaded albumin microspheres prepared by spray-drying. J Mi-croencapsul 2006 Sep; 23 (6): 632-42
    • (2006) J Mi-croencapsul , vol.23 , Issue.6 , pp. 632-42
    • Nettey, H.1    Haswani, D.2    Oettinger, C.W.3
  • 62
    • 45749086939 scopus 로고    scopus 로고
    • Preparation and in vivo evaluation of piroxicam-loaded gelatin microcapsule by spray drying technique
    • Jun
    • Piao MG, Yang CW, Li DX, et al. Preparation and in vivo evaluation of piroxicam-loaded gelatin microcapsule by spray drying technique. Biol Pharm Bull 2008 Jun; 31 (6): 1284-7
    • (2008) Biol Pharm Bull , vol.31 , Issue.6 , pp. 1284-7
    • Piao, M.G.1    Yang, C.W.2    Li, D.X.3
  • 63
    • 31144448189 scopus 로고    scopus 로고
    • Spray-dried chitosan/ethylcellulose microspheres for nasal drug delivery: Swelling study and evaluation of in vitro drug release properties
    • Aug
    • Martinac A, Filipovic-Grcic J, Perissutti B, et al. Spray-dried chitosan/ethylcellulose microspheres for nasal drug delivery: swelling study and evaluation of in vitro drug release properties. J Microencapsul 2005 Aug; 22 (5): 549-61
    • (2005) J Microencapsul , vol.22 , Issue.5 , pp. 549-61
    • Martinac, A.1    Filipovic-Grcic, J.2    Perissutti, B.3
  • 64
    • 0035118776 scopus 로고    scopus 로고
    • Preparation and analgesic activity of Eudragit RS100 microparticles containing diflunisal
    • Jan-Mar
    • Pignatello R, Amico D, Chiechio S, et al. Preparation and analgesic activity of Eudragit RS100 microparticles containing diflunisal. Drug Deliv 2001 Jan-Mar; 8 (1): 35-45
    • (2001) Drug Deliv , vol.8 , Issue.1 , pp. 35-45
    • Pignatello, R.1    Amico, D.2    Chiechio, S.3
  • 65
    • 0036155736 scopus 로고    scopus 로고
    • Gastro-resistant microspheres containing ketoprofen
    • Jan-Feb
    • Palmieri GF, Bonacucina G, Di Martino P, et al. Gastro-resistant microspheres containing ketoprofen. J Microencapsul 2002 Jan-Feb; 19 (1): 111-9
    • (2002) J Microencapsul , vol.19 , Issue.1 , pp. 111-9
    • Palmieri, G.F.1    Bonacucina, G.2    Di Martino, P.3
  • 66
    • 0037151472 scopus 로고    scopus 로고
    • Spray dried Eudragit microparticles as encapsulation devices for vitamin C
    • Aug 21
    • Esposito E, Cervellati F, Menegatti E, et al. Spray dried Eudragit microparticles as encapsulation devices for vitamin C. Int J Pharm 2002 Aug 21; 242 (1-2): 329-34
    • (2002) Int J Pharm , vol.242 , Issue.1-2 , pp. 329-34
    • Esposito, E.1    Cervellati, F.2    Menegatti, E.3
  • 67
    • 0034061648 scopus 로고    scopus 로고
    • Production of Eudragit microparticles by spray-drying technique: Influence of experimental parameters on morphological and dimensional characteristics
    • Esposito E, Roncarati R, Cortesi R, et al. Production of Eudragit microparticles by spray-drying technique: influence of experimental parameters on morphological and dimensional characteristics. Pharm Dev Technol 2000; 5 (2): 267-78
    • (2000) Pharm Dev Technol , vol.5 , Issue.2 , pp. 267-78
    • Esposito, E.1    Roncarati, R.2    Cortesi, R.3
  • 68
    • 0032855232 scopus 로고    scopus 로고
    • Microencapsulation of DNA using poly(DL-lactide-co-glycolide): Stability issues and release characteristics
    • Sep 20
    • Walter E, Moelling K, Pavlovic J, et al. Microencapsulation of DNA using poly(DL-lactide-co-glycolide): stability issues and release characteristics. J Control Release 1999 Sep 20; 61 (3): 361-74
    • (1999) J Control Release , vol.61 , Issue.3 , pp. 361-74
    • Walter, E.1    Moelling, K.2    Pavlovic, J.3
  • 69
    • 0037151568 scopus 로고    scopus 로고
    • Development of microparticles prepared by spray-drying as a vaccine delivery system against brucellosis
    • Aug 21
    • Murillo M, Gamazo C, Goni M, et al. Development of microparticles prepared by spray-drying as a vaccine delivery system against brucellosis. Int J Pharm 2002 Aug 21; 242 (1-2): 341-4
    • (2002) Int J Pharm , vol.242 , Issue.1-2 , pp. 341-4
    • Murillo, M.1    Gamazo, C.2    Goni, M.3
  • 70
    • 34248996631 scopus 로고    scopus 로고
    • Formulation of spray-dried phenytoin loaded poly(epsilon-caprolactone) microcarrier intended for brain delivery to treat epilepsy
    • May
    • Li Z, Li Q, Simon S, et al. Formulation of spray-dried phenytoin loaded poly(epsilon-caprolactone) microcarrier intended for brain delivery to treat epilepsy. J Pharm Sci 2007 May; 96 (5): 1018-30
    • (2007) J Pharm Sci , vol.96 , Issue.5 , pp. 1018-30
    • Li, Z.1    Li, Q.2    Simon, S.3
  • 71
    • 50149117923 scopus 로고    scopus 로고
    • Water-free microencapsulation of proteins within PLGA microparticles by spray drying using PEG-assisted protein solubilization technique in organic solvent
    • Sep
    • Mok H, Park TG. Water-free microencapsulation of proteins within PLGA microparticles by spray drying using PEG-assisted protein solubilization technique in organic solvent. Eur J Pharm Biopharm 2008 Sep; 70 (1): 137-44
    • (2008) Eur J Pharm Biopharm , vol.70 , Issue.1 , pp. 137-44
    • Mok, H.1    Park, T.G.2
  • 72
    • 0346099210 scopus 로고    scopus 로고
    • Poly(s-caprolactone) and Eudragit® microparticles containing fludrocortisone acetate
    • Gibaud S, Jabir Al Awwadi N, Ducki C, et al. Poly(s-caprolactone) and Eudragit® microparticles containing fludrocortisone acetate. Int J Pharm 2004; 269 (2): 491-508
    • (2004) Int J Pharm , vol.269 , Issue.2 , pp. 491-508
    • Gibaud, S.1    Jabir Al Awwadi, N.2    Ducki, C.3
  • 73
    • 40749083239 scopus 로고    scopus 로고
    • Engineering of poly(epsilon-caprolactone) microcarriers to modulate protein encapsulation capability and release kinetic
    • Apr
    • Coccoli V, Luciani A, Orsi S, et al. Engineering of poly(epsilon- caprolactone) microcarriers to modulate protein encapsulation capability and release kinetic. J Mater Sci Mater Med 2008 Apr; 19 (4): 1703-11
    • (2008) J Mater Sci Mater Med , vol.19 , Issue.4 , pp. 1703-11
    • Coccoli, V.1    Luciani, A.2    Orsi, S.3
  • 74
    • 18044391067 scopus 로고    scopus 로고
    • Formulation, characterization, and evaluation of ketorolac tromethamine-loaded biodegradable microspheres
    • May-Jun
    • Sinha VR, Trehan A. Formulation, characterization, and evaluation of ketorolac tromethamine-loaded biodegradable microspheres. Drug Deliv 2005 May-Jun; 12(3): 133-9
    • (2005) Drug Deliv , vol.12 , Issue.3 , pp. 133-9
    • Sinha, V.R.1    Trehan, A.2
  • 75
    • 0028244475 scopus 로고
    • Cellulose acetate butyrate and polycaprolactone for ketoprofen spray-dried microsphere preparation
    • Jul-Aug
    • Giunchedi P, Conti B, Maggi L, et al. Cellulose acetate butyrate and polycaprolactone for ketoprofen spray-dried microsphere preparation. J Microencapsul 1994 Jul-Aug; 11 (4): 381-93
    • (1994) J Microencapsul , vol.11 , Issue.4 , pp. 381-93
    • Giunchedi, P.1    Conti, B.2    Maggi, L.3
  • 76
    • 33751219844 scopus 로고    scopus 로고
    • Effect of formulation variables on the prediction of release from microparticles with experimental design
    • Dec 5
    • Luzardo-Alvarez A, Almeida-Prieto S, Fraga-Lopez F, et al. Effect of formulation variables on the prediction of release from microparticles with experimental design. J Appl Polym Sci 2006 Dec 5; 102 (5): 4546-53
    • (2006) J Appl Polym Sci , vol.102 , Issue.5 , pp. 4546-53
    • Luzardo-Alvarez, A.1    Almeida-Prieto, S.2    Fraga-Lopez, F.3
  • 77
    • 0042971718 scopus 로고    scopus 로고
    • Oral insulin: A perspective
    • Jan 1
    • Raj NKK, Sharma CP. Oral insulin: a perspective. J Biomater Appl 2003 Jan 1; 17 (3): 183-96
    • (2003) J Biomater Appl , vol.17 , Issue.3 , pp. 183-96
    • Nkk, R.1    Sharma, C.P.2
  • 78
    • 15544385237 scopus 로고    scopus 로고
    • Biodegradable polymers for microencapsulation of drugs
    • Jan 31
    • Park JH, Ye M, Park K. Biodegradable polymers for microencapsulation of drugs. Molecules 2005 Jan 31; 10 (1): 146-61
    • (2005) Molecules , vol.10 , Issue.1 , pp. 146-61
    • Park, J.H.1    Ye, M.2    Park, K.3
  • 79
    • 44649091155 scopus 로고    scopus 로고
    • A comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins
    • Sivadas N, O'Rourke D, Tobin A, et al. A comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins. Int J Pharm 2008; 358 (1-2): 159-67
    • (2008) Int J Pharm , vol.358 , Issue.1-2 , pp. 159-67
    • Sivadas, N.1    O'Rourke, D.2    Tobin, A.3
  • 80
    • 0033937214 scopus 로고    scopus 로고
    • Influence of various technological parameters on the preparation of spray-dried poly(epsilon-caprolactone) micro-particles containing a model antigen
    • Jul-Aug
    • Baras B, Benoit MA, Gillard J. Influence of various technological parameters on the preparation of spray-dried poly(epsilon-caprolactone) micro-particles containing a model antigen. J Microencapsul 2000 Jul-Aug; 17 (4): 485-98
    • (2000) J Microencapsul , vol.17 , Issue.4 , pp. 485-98
    • Baras, B.1    Benoit, M.A.2    Gillard, J.3
  • 81
    • 0032403502 scopus 로고    scopus 로고
    • Microparticles and polymers for the mucosal delivery of vaccines
    • O'Hagan DT. Microparticles and polymers for the mucosal delivery of vaccines. Adv Drug Deliv Rev 1998; 34 (2-3): 305-20
    • (1998) Adv Drug Deliv Rev , vol.34 , Issue.2-3 , pp. 305-20
    • O'Hagan, D.T.1
  • 82
    • 0035940318 scopus 로고    scopus 로고
    • Microparticles for intranasal immunization
    • Sep 23
    • Vajdy M, O'Hagan DT. Microparticles for intranasal immunization. Adv Drug Deliv Rev 2001 Sep 23; 51 (1-3): 127-41
    • (2001) Adv Drug Deliv Rev , vol.51 , Issue.1-3 , pp. 127-41
    • Vajdy, M.1    O'Hagan, D.T.2
  • 84
    • 0037472115 scopus 로고    scopus 로고
    • Chitosan-based gastrointestinal delivery systems
    • Apr 29
    • Hejazi R, Amiji M. Chitosan-based gastrointestinal delivery systems. J Control Release 2003 Apr 29; 89 (2): 151-65
    • (2003) J Control Release , vol.89 , Issue.2 , pp. 151-65
    • Hejazi, R.1    Amiji, M.2
  • 85
    • 38349080964 scopus 로고    scopus 로고
    • Preparation and characterization of theophylline loaded chitosan/beta-cyclodextrin microspheres
    • Jan
    • Zhang WF, Chen XG, Li PW, et al. Preparation and characterization of theophylline loaded chitosan/beta-cyclodextrin microspheres. J Mater Sci Mater Med 2008 Jan; 19 (1): 305-10
    • (2008) J Mater Sci Mater Med , vol.19 , Issue.1 , pp. 305-10
    • Zhang, W.F.1    Chen, X.G.2    Li, P.W.3
  • 86
    • 15044355133 scopus 로고    scopus 로고
    • Pharmacological activity of peroral chitosan-insulin nanoparticles in diabetic rats
    • Apr 11
    • Ma Z, Lim TM, Lim LY. Pharmacological activity of peroral chitosan-insulin nanoparticles in diabetic rats. Int J Pharm 2005 Apr 11; 293 (1-2): 271-80
    • (2005) Int J Pharm , vol.293 , Issue.1-2 , pp. 271-80
    • Ma, Z.1    Lim, T.M.2    Lim, L.Y.3
  • 87
    • 33846410236 scopus 로고    scopus 로고
    • Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery
    • Jan
    • Lin YH, Mi FL, Chen CT, et al. Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery. Biomacromolecules 2007 Jan; 8 (1): 146-52
    • (2007) Biomacromolecules , vol.8 , Issue.1 , pp. 146-52
    • Lin, Y.H.1    Mi, F.L.2    Chen, C.T.3
  • 88
    • 0037027876 scopus 로고    scopus 로고
    • Bioadhesive polysaccharide in protein delivery system: Chitosan nanoparticles improve the intestinal absorption of insulin in vivo
    • Dec 5
    • Pan Y, Li YJ, Zhao HY, et al. Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int J Pharm 2002 Dec 5; 249 (1-2): 139-47
    • (2002) Int J Pharm , vol.249 , Issue.1-2 , pp. 139-47
    • Pan, Y.1    Li, Y.J.2    Zhao, H.Y.3
  • 89
    • 0037820592 scopus 로고    scopus 로고
    • The characteristics of betamethasoneloaded chitosan microparticles by spray-drying method
    • Jul-Aug
    • Huang YC, Yeh MK, Cheng SN, et al. The characteristics of betamethasoneloaded chitosan microparticles by spray-drying method. J Microencapsul 2003 Jul-Aug; 20 (4): 459-72
    • (2003) J Microencapsul , vol.20 , Issue.4 , pp. 459-72
    • Huang, Y.C.1    Yeh, M.K.2    Cheng, S.N.3
  • 90
    • 37849013757 scopus 로고    scopus 로고
    • Chitosan-based spray-dried respirable powders for sustained delivery of terbutaline sulfate
    • Feb
    • Learoyd TP, Burrows JL, French E, et al. Chitosan-based spray-dried respirable powders for sustained delivery of terbutaline sulfate. Eur J Pharm Biopharm 2008 Feb; 68 (2): 224-34
    • (2008) Eur J Pharm Biopharm , vol.68 , Issue.2 , pp. 224-34
    • Learoyd, T.P.1    Burrows, J.L.2    French, E.3
  • 91
    • 0344352463 scopus 로고    scopus 로고
    • Protein release from alginate matrices
    • May 4
    • Wee S, Gombotz WR. Protein release from alginate matrices. Adv Drug Deliv Rev 1998 May 4; 31 (3): 267-85
    • (1998) Adv Drug Deliv Rev , vol.31 , Issue.3 , pp. 267-85
    • Wee, S.1    Gombotz, W.R.2
  • 92
    • 33748631285 scopus 로고    scopus 로고
    • Characterization of insulin-loaded alginate nanoparticles produced by ionotropic pre-gelation through DSC and FTIR studies
    • Sarmento B, Ferreira D, Veiga F, et al. Characterization of insulin-loaded alginate nanoparticles produced by ionotropic pre-gelation through DSC and FTIR studies. Carbohydr Polym 2006; 66 (1): 1-7
    • (2006) Carbohydr Polym , vol.66 , Issue.1 , pp. 1-7
    • Sarmento, B.1    Ferreira, D.2    Veiga, F.3
  • 93
    • 33746474818 scopus 로고    scopus 로고
    • Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan-a review
    • George M, Abraham TE. Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan-a review. J Control Release 2006; 114 (1): 1-14
    • (2006) J Control Release , vol.114 , Issue.1 , pp. 1-14
    • George, M.1    Abraham, T.E.2
  • 94
    • 33748321119 scopus 로고    scopus 로고
    • Alginate hydrogels as biomaterials
    • Aug 7
    • Augst AD, Kong HJ, Mooney DJ. Alginate hydrogels as biomaterials. Macromol Biosci 2006 Aug 7; 6 (8): 623-33
    • (2006) Macromol Biosci , vol.6 , Issue.8 , pp. 623-33
    • Augst, A.D.1    Kong, H.J.2    Mooney, D.J.3
  • 95
    • 0023865866 scopus 로고
    • Alginates
    • Gacesa P. Alginates. Carbohydr Polym 1988; 8 (3): 161-82
    • (1988) Carbohydr Polym , vol.8 , Issue.3 , pp. 161-82
    • Gacesa, P.1
  • 96
    • 42649137232 scopus 로고    scopus 로고
    • Targeted delivery of nanoparticles for the treatment of lung diseases
    • May 22
    • Azarmi S, Roa WH, Lobenberg R. Targeted delivery of nanoparticles for the treatment of lung diseases. Adv Drug Deliv Rev 2008 May 22; 60 (8): 863-75
    • (2008) Adv Drug Deliv Rev , vol.60 , Issue.8 , pp. 863-75
    • Azarmi, S.1    Roa, W.H.2    Lobenberg, R.3
  • 97
    • 42949108724 scopus 로고    scopus 로고
    • Back to basics: The development of a simple, homogenous, two-component dry-powder inhaler formulation for the delivery of budesonide using miscible vinyl polymers
    • Mar
    • Buttini F, Colombo P, Wenger MP, et al. Back to basics: the development of a simple, homogenous, two-component dry-powder inhaler formulation for the delivery of budesonide using miscible vinyl polymers. J Pharm Sci 2008 Mar; 97 (3): 1257-67
    • (2008) J Pharm Sci , vol.97 , Issue.3 , pp. 1257-67
    • Buttini, F.1    Colombo, P.2    Wenger, M.P.3
  • 98
    • 43049085459 scopus 로고    scopus 로고
    • Preparation and properties of inhalable nanocomposite particles: Effects of the size, weight ratio of the primary nanoparticles in nanocomposite particles and temperature at a spray-dryer inlet upon properties of nanocomposite particles
    • Jun 15
    • Tomoda K, Ohkoshi T, Nakajima T, et al. Preparation and properties of inhalable nanocomposite particles: effects of the size, weight ratio of the primary nanoparticles in nanocomposite particles and temperature at a spray-dryer inlet upon properties of nanocomposite particles. Colloids Surf B Biointerfaces 2008 Jun 15; 64 (1): 70-6
    • (2008) Colloids Surf B Biointerfaces , vol.64 , Issue.1 , pp. 70-6
    • Tomoda, K.1    Ohkoshi, T.2    Nakajima, T.3
  • 99
    • 0036632415 scopus 로고    scopus 로고
    • Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying
    • Jul-Aug
    • Seville PC, Kellaway IW, Birchall JC. Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying. J Gene Med 2002 Jul-Aug; 4 (4): 428-37
    • (2002) J Gene Med , vol.4 , Issue.4 , pp. 428-37
    • Seville, P.C.1    Kellaway, I.W.2    Birchall, J.C.3
  • 100
    • 70349312538 scopus 로고    scopus 로고
    • Preparation of honokiol-loaded chitosan microparticles via spray-drying method intended for pulmonary delivery
    • Apr
    • Li X, Guo Q, Zheng X, et al. Preparation of honokiol-loaded chitosan microparticles via spray-drying method intended for pulmonary delivery. Drug Deliv 2009 Apr; 16 (3): 160-6
    • (2009) Drug Deliv , vol.16 , Issue.3 , pp. 160-6
    • Li, X.1    Guo, Q.2    Zheng, X.3
  • 101
    • 54549092578 scopus 로고    scopus 로고
    • Modified release of beclometasone dipropionate from chitosan-based spray-dried respirable powders
    • Learoyd TP, Burrows JL, French E, et al. Modified release of beclometasone dipropionate from chitosan-based spray-dried respirable powders. Powder Technol 2008; 187 (3): 231-8
    • (2008) Powder Technol , vol.187 , Issue.3 , pp. 231-8
    • Learoyd, T.P.1    Burrows, J.L.2    French, E.3
  • 102
    • 1642528390 scopus 로고    scopus 로고
    • Fluconazole encapsulation in PLGA microspheres by spray-drying
    • Mar
    • Rivera PA, Martinez-Oharriz MC, Rubio M, et al. Fluconazole encapsulation in PLGA microspheres by spray-drying. J Microencapsul 2004 Mar; 21 (2): 203-11
    • (2004) J Microencapsul , vol.21 , Issue.2 , pp. 203-11
    • Rivera, P.A.1    Martinez-Oharriz, M.C.2    Rubio, M.3
  • 103
    • 36249017868 scopus 로고    scopus 로고
    • Nanoparticles for drug delivery to the lungs
    • Dec
    • Sung JC, Pulliam BL, Edwards DA. Nanoparticles for drug delivery to the lungs. Trends Biotechnol 2007 Dec; 25 (12): 563-70
    • (2007) Trends Biotechnol , vol.25 , Issue.12 , pp. 563-70
    • Sung, J.C.1    Pulliam, B.L.2    Edwards, D.A.3
  • 104
    • 20744434748 scopus 로고    scopus 로고
    • Microencapsulated chitosan nanoparticles for lung protein delivery
    • Jul-Aug
    • Grenha A, Seijo B, Remunan-Lopez C. Microencapsulated chitosan nanoparticles for lung protein delivery. Eur J Pharm Sci 2005 Jul-Aug; 25 (4-5): 427-37
    • (2005) Eur J Pharm Sci , vol.25 , Issue.4-5 , pp. 427-37
    • Grenha, A.1    Seijo, B.2    Remunan-Lopez, C.3
  • 105
    • 52449086630 scopus 로고    scopus 로고
    • Cospray dried antibiotics for dry powder lung delivery
    • Aug
    • Adi H, Young PM, Chan HK, et al. Cospray dried antibiotics for dry powder lung delivery. J Pharm Sci 2008 Aug; 97 (8): 3356-66
    • (2008) J Pharm Sci , vol.97 , Issue.8 , pp. 3356-66
    • Adi, H.1    Young, P.M.2    Chan, H.K.3
  • 106
    • 41549155028 scopus 로고    scopus 로고
    • Microspheres containing lipid/chitosan nanoparticles complexes for pulmonary delivery of therapeutic proteins
    • May
    • Grenha A, Remunan-Lopez C, Carvalho EL, et al. Microspheres containing lipid/chitosan nanoparticles complexes for pulmonary delivery of therapeutic proteins. Eur J Pharm Biopharm 2008 May; 69 (1): 83-93
    • (2008) Eur J Pharm Biopharm , vol.69 , Issue.1 , pp. 83-93
    • Grenha, A.1    Remunan-Lopez, C.2    Carvalho, E.L.3
  • 108
    • 34548031589 scopus 로고    scopus 로고
    • Peptide drug delivery strategies for the treatment of diabetes
    • Aug
    • Sadrzadeh N, Glembourtt MJ, Stevenson CL. Peptide drug delivery strategies for the treatment of diabetes. J Pharm Sci 2007 Aug; 96 (8): 1925-54
    • (2007) J Pharm Sci , vol.96 , Issue.8 , pp. 1925-54
    • Sadrzadeh, N.1    Glembourtt, M.J.2    Stevenson, C.L.3
  • 109
    • 0032403533 scopus 로고    scopus 로고
    • Oral particulate delivery: Status and future trends
    • Dec 1
    • Chen H, Langer R. Oral particulate delivery: status and future trends. Adv Drug Deliv Rev 1998 Dec 1; 34 (2-3): 339-50
    • (1998) Adv Drug Deliv Rev , vol.34 , Issue.2-3 , pp. 339-50
    • Chen, H.1    Langer, R.2
  • 110
    • 33645037815 scopus 로고    scopus 로고
    • Ionotropic cross-linked chitosan microspheres for controlled release of ampicillin
    • Anal AK, Stevens WF, Remunan-Lopez C. Ionotropic cross-linked chitosan microspheres for controlled release of ampicillin. Int J Pharm 2006; 312 (1-2): 166-73
    • (2006) Int J Pharm , vol.312 , Issue.1-2 , pp. 166-73
    • Anal, A.K.1    Stevens, W.F.2    Remunan-Lopez, C.3
  • 111
    • 0034756313 scopus 로고    scopus 로고
    • Production of insulin-loaded poly(-ethylene glycol)/poly(l-lactide) (PEG/PLA) nanoparticles by gas antisolvent techniques
    • Oct
    • Elvassore N, Bertucco A, Caliceti P. Production of insulin-loaded poly(-ethylene glycol)/poly(l-lactide) (PEG/PLA) nanoparticles by gas antisolvent techniques. J Pharm Sci 2001 Oct; 90 (10): 1628-36
    • (2001) J Pharm Sci , vol.90 , Issue.10 , pp. 1628-36
    • Elvassore, N.1    Bertucco, A.2    Caliceti, P.3
  • 112
    • 33750107814 scopus 로고    scopus 로고
    • Microcapsules formulated in the enteric coating copolymer Eudragit L100 as delivery systems for oral vaccination against infections by gastrointestinal nematode parasites
    • Sep
    • Dea-Ayuela MA, Rama-Iniguez S, Torrado-Santiago S, et al. Microcapsules formulated in the enteric coating copolymer Eudragit L100 as delivery systems for oral vaccination against infections by gastrointestinal nematode parasites. J Drug Target 2006 Sep; 14 (8): 567-75
    • (2006) J Drug Target , vol.14 , Issue.8 , pp. 567-75
    • Dea-Ayuela, M.A.1    Rama-Iniguez, S.2    Torrado-Santiago, S.3
  • 113
    • 0035083556 scopus 로고    scopus 로고
    • Spray-drying as a method for microparticulate controlled release systems preparation: Advantages and limits. I. Water-soluble drugs
    • Palmieri GF, Bonacucina G, Di Martino P, et al. Spray-drying as a method for microparticulate controlled release systems preparation: advantages and limits. I. Water-soluble drugs. Drug Dev Ind Pharm 2001; 27 (3): 195-204
    • (2001) Drug Dev Ind Pharm , vol.27 , Issue.3 , pp. 195-204
    • Palmieri, G.F.1    Bonacucina, G.2    Di Martino, P.3
  • 114
    • 33845712848 scopus 로고    scopus 로고
    • Spray drying conditions and encapsulating composition effects on formation and properties of sodium diclofenac micro-particles
    • Rattes ALR, Oliveira WP. Spray drying conditions and encapsulating composition effects on formation and properties of sodium diclofenac micro-particles. Powder Technology 2007; 171 (1): 7-14
    • (2007) Powder Technology , vol.171 , Issue.1 , pp. 7-14
    • Alr, R.1    Oliveira, W.P.2
  • 115
    • 77956397487 scopus 로고    scopus 로고
    • Effects of microwave on drug-release responses of spray-dried alginate microspheres
    • Epub 2010 Apr 12
    • Mardziah RE, Wong TW. Effects of microwave on drug-release responses of spray-dried alginate microspheres. Drug Dev Ind Pharm. Epub 2010 Apr 12
    • Drug Dev Ind Pharm.
    • Mardziah, R.E.1    Wong, T.W.2
  • 116
    • 77949894716 scopus 로고    scopus 로고
    • Bioefficacy of budesonide loaded crosslinked polyelectrolyte microparticles in rat model of induced colitis
    • Dec
    • Simonoska Crcarevska M, Glavas Dodov M, Petrusevska G, et al. Bioefficacy of budesonide loaded crosslinked polyelectrolyte microparticles in rat model of induced colitis. J Drug Target 2009 Dec; 17 (10): 788-802
    • (2009) J Drug Target , vol.17 , Issue.10 , pp. 788-802
    • Simonoska Crcarevska, M.1    Glavas Dodov, M.2    Petrusevska, G.3
  • 117
    • 39849085517 scopus 로고    scopus 로고
    • Chitosan coated Ca-alginate microparticles loaded with budesonide for delivery to the inflamed colonic mucosa
    • Simonoska Crcarevska M, Glavas Dodov M, Goracinova K. Chitosan coated Ca-alginate microparticles loaded with budesonide for delivery to the inflamed colonic mucosa. Eur J Pharm Biopharm 2008; 68 (3): 565-78
    • (2008) Eur J Pharm Biopharm , vol.68 , Issue.3 , pp. 565-78
    • Simonoska Crcarevska, M.1    Glavas Dodov, M.2    Goracinova, K.3
  • 118
    • 38349181604 scopus 로고    scopus 로고
    • Toxicity and gut associated lymphoid tissue translocation of polymyxin B orally administered by alginate/chitosan microparticles in rats
    • Jan
    • Coppi G, Bondi M, Coppi A, et al. Toxicity and gut associated lymphoid tissue translocation of polymyxin B orally administered by alginate/chitosan microparticles in rats. J Pharm Pharmacol 2008 Jan; 60 (1): 21-6
    • (2008) J Pharm Pharmacol , vol.60 , Issue.1 , pp. 21-6
    • Coppi, G.1    Bondi, M.2    Coppi, A.3
  • 119
    • 33744754708 scopus 로고    scopus 로고
    • Effect of manufacturing parameters on the characteristics of vitamin C encapsulated tripolyphosphate-chitosan microspheres prepared by spray-drying
    • Feb
    • Desai KG, Park HJ. Effect of manufacturing parameters on the characteristics of vitamin C encapsulated tripolyphosphate-chitosan microspheres prepared by spray-drying. J Microencapsul 2006 Feb; 23 (1): 91-103
    • (2006) J Microencapsul , vol.23 , Issue.1 , pp. 91-103
    • Desai, K.G.1    Park, H.J.2
  • 120
    • 33749593093 scopus 로고    scopus 로고
    • Sodium pantoprazole-loaded enteric microparticles preparedbyspray drying: Effect of the scaleofproduction and process validation
    • Oct 31
    • Raffin RP, Jornada DS, Re MI, et al. Sodium pantoprazole-loaded enteric microparticles preparedbyspray drying: effect of the scaleofproduction and process validation. Int J Pharm 2006 Oct 31; 324 (1): 10-8
    • (2006) Int J Pharm , vol.324 , Issue.1 , pp. 10-8
    • Raffin, R.P.1    Jornada, D.S.2    Re, M.I.3
  • 121
    • 12144273501 scopus 로고    scopus 로고
    • Etal. Alginate microparticles for Polymyxin B Peyer's patches uptake: Microparticles for antibiotic oral administration
    • Dec
    • Coppi G, Iannuccelli V, Sala N, etal. Alginate microparticles for Polymyxin B Peyer's patches uptake: microparticles for antibiotic oral administration. J Microencapsul 2004 Dec; 21 (8): 829-39
    • (2004) J Microencapsul , vol.21 , Issue.8 , pp. 829-39
    • Coppi, G.1    Iannuccelli, V.2    Sala, N.3
  • 122
    • 0037369394 scopus 로고    scopus 로고
    • Compressed biodegradable matrices of spray-dried PLGA microspheres for the modified release of ketoprofen
    • Mar-Apr
    • Gavini E, Sanna V, Juliano C, et al. Compressed biodegradable matrices of spray-dried PLGA microspheres for the modified release of ketoprofen. J Microencapsul 2003 Mar-Apr; 20 (2): 193-201
    • (2003) J Microencapsul , vol.20 , Issue.2 , pp. 193-201
    • Gavini, E.1    Sanna, V.2    Juliano, C.3
  • 123
    • 0035187727 scopus 로고    scopus 로고
    • Spray-dried microspheres containing ketoprofen formulated into capsules and tablets
    • Jan-Feb
    • Moretti MD, Gavini E, Juliano C, et al. Spray-dried microspheres containing ketoprofen formulated into capsules and tablets. J Microencapsul 2001 Jan-Feb; 18 (1): 111-21
    • (2001) J Microencapsul , vol.18 , Issue.1 , pp. 111-21
    • Moretti, M.D.1    Gavini, E.2    Juliano, C.3
  • 124
    • 58149271083 scopus 로고    scopus 로고
    • Pectin-based microspheres for colonspecific delivery of vancomycin
    • Jan
    • Bigucci F, Luppi B, Monaco L, et al. Pectin-based microspheres for colonspecific delivery of vancomycin. J Pharm Pharmacol 2009 Jan; 61 (1): 41-6
    • (2009) J Pharm Pharmacol , vol.61 , Issue.1 , pp. 41-6
    • Bigucci, F.1    Luppi, B.2    Monaco, L.3
  • 125
    • 0032473392 scopus 로고    scopus 로고
    • Design of microencapsulated chitosan microspheres for colonic drug delivery
    • Lorenzo-Lamosa ML, Remunan-Lopez C, Vila-Jato JL, et al. Design of microencapsulated chitosan microspheres for colonic drug delivery. J Control Release 1998; 52 (1-2): 109-18
    • (1998) J Control Release , vol.52 , Issue.1-2 , pp. 109-18
    • Lorenzo-Lamosa, M.L.1    Remunan-Lopez, C.2    Vila-Jato, J.L.3
  • 126
    • 0034049555 scopus 로고    scopus 로고
    • Spray-dried lactose composite particles containing an ion complex of alginate-chitosan for designing a dry-coated tablet having a time-controlled releasing function
    • Jan
    • Takeuchi H, Yasuji T, Yamamoto H, et al. Spray-dried lactose composite particles containing an ion complex of alginate-chitosan for designing a dry-coated tablet having a time-controlled releasing function. Pharm Res 2000 Jan; 17 (1): 94-9
    • (2000) Pharm Res , vol.17 , Issue.1 , pp. 94-9
    • Takeuchi, H.1    Yasuji, T.2    Yamamoto, H.3
  • 127
    • 36048993052 scopus 로고    scopus 로고
    • 5-ASA loaded chitosan-Ca-alginate microparticles: Preparation and physicochemical characterization
    • Dec 10
    • Mladenovska K, Cruaud O, Richomme P, et al. 5-ASA loaded chitosan-Ca-alginate microparticles: preparation and physicochemical characterization. Int J Pharm 2007 Dec 10; 345 (1-2): 59-69
    • (2007) Int J Pharm , vol.345 , Issue.1-2 , pp. 59-69
    • Mladenovska, K.1    Cruaud, O.2    Richomme, P.3
  • 128
    • 33846186854 scopus 로고    scopus 로고
    • Novel colon-specific microspheres with highly dispersed hydroxycamptothecin cores: Their preparation, release behavior, and therapeutic efficiency against colonic cancer
    • Dec
    • Lu B, Zhang Z. Novel colon-specific microspheres with highly dispersed hydroxycamptothecin cores: their preparation, release behavior, and therapeutic efficiency against colonic cancer. J Pharm Sci 2006 Dec; 95 (12): 2619-30
    • (2006) J Pharm Sci , vol.95 , Issue.12 , pp. 2619-30
    • Lu, B.1    Zhang, Z.2
  • 129
    • 1442359755 scopus 로고    scopus 로고
    • PLGA microspheres for the ocular delivery of a peptide drug, vancomycin using emulsification/spray-drying as the preparation method: In vitro/in vivo studies
    • Mar
    • Gavini E, Chetoni P, Cossu M, et al. PLGA microspheres for the ocular delivery of a peptide drug, vancomycin using emulsification/spray-drying as the preparation method: in vitro/in vivo studies. Eur J Pharm Biopharm 2004 Mar; 57 (2): 207-12
    • (2004) Eur J Pharm Biopharm , vol.57 , Issue.2 , pp. 207-12
    • Gavini, E.1    Chetoni, P.2    Cossu, M.3
  • 130
    • 55149113724 scopus 로고    scopus 로고
    • Brain uptakeof an anti-ischemic agent by nasal administration of microparticles
    • Nov
    • Dalpiaz A, GaviniE,ColomboG, et al. Brain uptakeof an anti-ischemic agent by nasal administration of microparticles. J Pharm Sci 2008 Nov; 97 (11): 4889-903
    • (2008) J Pharm Sci , vol.97 , Issue.11 , pp. 4889-903
    • Dalpiaz, A.1    Gavini, E.2    Colombo, G.3
  • 131
    • 37848999302 scopus 로고    scopus 로고
    • Spray-dried microspheres based on methylpyrrolidinone chitosan as new carrier for nasal administration of metoclopramide
    • Feb
    • Gavini E, Rassu G, Muzzarelli C, et al. Spray-dried microspheres based on methylpyrrolidinone chitosan as new carrier for nasal administration of metoclopramide. Eur J Pharm Biopharm 2008 Feb; 68 (2): 245-52
    • (2008) Eur J Pharm Biopharm , vol.68 , Issue.2 , pp. 245-52
    • Gavini, E.1    Rassu, G.2    Muzzarelli, C.3
  • 132
    • 0023205098 scopus 로고
    • Bioadhesive microspheres as a potential nasal drug delivery system
    • Illum L, Jørgensen H, Bisgaard H, et al. Bioadhesive microspheres as a potential nasal drug delivery system. Int J Pharm 1987; 39 (3): 189-99
    • (1987) Int J Pharm , vol.39 , Issue.3 , pp. 189-99
    • Illum, L.1    Jørgensen, H.2    Bisgaard, H.3
  • 133
    • 26444507776 scopus 로고    scopus 로고
    • Chitosan and poly(methyl vinyl ether-co-maleic anhydride) microparticles as nasal sustained delivery systems
    • Cerchiara T, Luppi B, Chidichimo G, et al. Chitosan and poly(methyl vinyl ether-co-maleic anhydride) microparticles as nasal sustained delivery systems. Eur J Pharm Biopharm 2005; 61 (3): 195-200
    • (2005) Eur J Pharm Biopharm , vol.61 , Issue.3 , pp. 195-200
    • Cerchiara, T.1    Luppi, B.2    Chidichimo, G.3
  • 134
    • 70349120301 scopus 로고    scopus 로고
    • Preparation of zolmitriptan-chitosan microparticlesby spray drying for nasal delivery
    • Oct 8
    • Alhalaweh A, Andersson S, Velaga SP. Preparation of zolmitriptan-chitosan microparticlesby spray drying for nasal delivery. Eur J Pharm Sci 2009 Oct 8; 38 (3): 206-14
    • (2009) Eur J Pharm Sci , vol.38 , Issue.3 , pp. 206-14
    • Alhalaweh, A.1    Andersson, S.2    Velaga, S.P.3
  • 135
    • 68649123770 scopus 로고    scopus 로고
    • Effect on the nasal bioavailability of co-processing drug and bioadhesive carrier via spray-drying
    • Sep 8
    • Coucke D, Vervaet C, Foreman P, et al. Effect on the nasal bioavailability of co-processing drug and bioadhesive carrier via spray-drying. Int J Pharm 2009 Sep 8; 379 (1): 67-71
    • (2009) Int J Pharm , vol.379 , Issue.1 , pp. 67-71
    • Coucke, D.1    Vervaet, C.2    Foreman, P.3
  • 136
    • 70449411953 scopus 로고    scopus 로고
    • Formulation and evaluation of nasal mucoadhesive microspheres of sumatriptan succinate
    • Dec
    • Jain SA, Chauk DS, Mahajan HS, et al. Formulation and evaluation of nasal mucoadhesive microspheres of sumatriptan succinate. J Microencapsul 2009 Dec; 26 (8): 711-21
    • (2009) J Microencapsul , vol.26 , Issue.8 , pp. 711-21
    • Jain, S.A.1    Chauk, D.S.2    Mahajan, H.S.3
  • 137
    • 61649108379 scopus 로고    scopus 로고
    • The effect of chitosan molecular weight on the characteristics of spray-dried methotrexate-loaded chitosan microspheres for nasal administration
    • Mar
    • Sun Y, Cui F, Shi K, et al. The effect of chitosan molecular weight on the characteristics of spray-dried methotrexate-loaded chitosan microspheres for nasal administration. Drug Dev Ind Pharm 2009 Mar; 35 (3): 379-86
    • (2009) Drug Dev Ind Pharm , vol.35 , Issue.3 , pp. 379-86
    • Sun, Y.1    Cui, F.2    Shi, K.3
  • 138
    • 13544275751 scopus 로고    scopus 로고
    • Development and bioadhesive properties of chitosan-ethylcellulose microspheres for nasal delivery
    • Mar 3
    • Martinac A, Filipovic-Grcic J, Voinovich D, et al. Development and bioadhesive properties of chitosan-ethylcellulose microspheres for nasal delivery. Int J Pharm 2005 Mar 3; 291 (1-2): 69-77
    • (2005) Int J Pharm , vol.291 , Issue.1-2 , pp. 69-77
    • Martinac, A.1    Filipovic-Grcic, J.2    Voinovich, D.3
  • 139
    • 0041967089 scopus 로고    scopus 로고
    • Mucoadhesive microspheres containing gentamicin sulfate for nasal administration: Preparation and in vitro characterization
    • Jan
    • Hascicek C, Gonul N, Erk N. Mucoadhesive microspheres containing gentamicin sulfate for nasal administration: preparation and in vitro characterization. Farmaco 2003 Jan; 58 (1): 11-6
    • (2003) Farmaco , vol.58 , Issue.1 , pp. 11-6
    • Hascicek, C.1    Gonul, N.2    Erk, N.3
  • 140
    • 63149131275 scopus 로고    scopus 로고
    • Development and testing of particulate formulations for the nasal delivery of antibodies
    • Apr 17
    • Kaye RS, Purewal TS, Alpar OH. Development and testing of particulate formulations for the nasal delivery of antibodies. JControl Release 2009 Apr 17; 135 (2): 127-35
    • (2009) JControl Release , vol.135 , Issue.2 , pp. 127-35
    • Kaye, R.S.1    Purewal, T.S.2    Alpar, O.H.3
  • 141
    • 77949716923 scopus 로고    scopus 로고
    • Optimization of prednisolone acetateloaded chitosan microspheres using a 2(3) factorial design for preventing restenosis
    • Apr
    • Sarisozen C, Arica B, Orman MN, et al. Optimization of prednisolone acetateloaded chitosan microspheres using a 2(3) factorial design for preventing restenosis. Drug Deliv 2010 Apr; 17 (3): 178-86
    • (2010) Drug Deliv , vol.17 , Issue.3 , pp. 178-86
    • Sarisozen, C.1    Arica, B.2    Orman, M.N.3
  • 142
    • 70350671701 scopus 로고    scopus 로고
    • Preparation and characterization of spray-dried mucoadhesive microspheres of aceclofenac
    • Oct
    • Nagda C, Chotai NP, Patel U, et al. Preparation and characterization of spray-dried mucoadhesive microspheres of aceclofenac. Drug Dev Ind Pharm 2009 Oct; 35 (10): 1155-66
    • (2009) Drug Dev Ind Pharm , vol.35 , Issue.10 , pp. 1155-66
    • Nagda, C.1    Chotai, N.P.2    Patel, U.3
  • 143
    • 70449346695 scopus 로고    scopus 로고
    • Preparation and evaluation of microspheres prepared from novel polyester-ibuprofen conjugates blended with non-conjugated ibuprofen
    • Dec
    • Thompson CJ, Hansford D, Higgins S, et al. Preparation and evaluation of microspheres prepared from novel polyester-ibuprofen conjugates blended with non-conjugated ibuprofen. J Microencapsul 2009 Dec; 26 (8): 676-83
    • (2009) J Microencapsul , vol.26 , Issue.8 , pp. 676-83
    • Thompson, C.J.1    Hansford, D.2    Higgins, S.3
  • 144
    • 47249107745 scopus 로고    scopus 로고
    • Dextrin-microencapsulated porphyrin: Luminescent properties
    • Luz PP, Neri CR, Serra OA. Dextrin-microencapsulated porphyrin: luminescent properties. Ann N Y Acad Sci 2008; 1130: 91-6
    • (2008) Ann N y Acad Sci , vol.1130 , pp. 91-6
    • Luz, P.P.1    Neri, C.R.2    Serra, O.A.3
  • 145
    • 52449107294 scopus 로고    scopus 로고
    • Ketotifen-loaded microspheres prepared by spray-drying poly(DL-lactide) and poly(DL-lactide-co-glycolide) polymers: Characterization and in vivo evaluation
    • Aug
    • Guerrero S, MunizE, TeijonC,et al. Ketotifen-loaded microspheres prepared by spray-drying poly(D,L-lactide) and poly(D,L-lactide-co-glycolide) polymers: characterization and in vivo evaluation. J Pharm Sci 2008 Aug; 97 (8): 3153-69
    • (2008) J Pharm Sci , vol.97 , Issue.8 , pp. 3153-69
    • Guerrero, S.1    Muniz, E.2    Teijon, C.3
  • 146
    • 55849152841 scopus 로고    scopus 로고
    • Microencapsulation of doxycycline into poly(lactide-co-glycolide) by spray drying technique: Effect of polymer molecular weight on process parameters
    • Patel P, Mundargi RC, Babu VR, et al. Microencapsulation of doxycycline into poly(lactide-co-glycolide) by spray drying technique: effect of polymer molecular weight on process parameters. J Appl Polym Sci 2008; 108 (6): 4038-46
    • (2008) J Appl Polym Sci , vol.108 , Issue.6 , pp. 4038-46
    • Patel, P.1    Mundargi, R.C.2    Babu, V.R.3
  • 147
    • 30844456231 scopus 로고    scopus 로고
    • 5-Fluorouracil-loaded microspheres prepared by spray-drying poly(D,L-lactide) and poly(lactide-co-glycolide) polymers: Characterization and drug release
    • Sep
    • Blanco MD, Sastre RL, Teijon C, et al. 5-Fluorouracil-loaded microspheres prepared by spray-drying poly(D,L-lactide) and poly(lactide-co-glycolide) polymers: characterization and drug release. J Microencapsul 2005 Sep; 22 (6): 671-82
    • (2005) J Microencapsul , vol.22 , Issue.6 , pp. 671-82
    • Blanco, M.D.1    Sastre, R.L.2    Teijon, C.3
  • 148
    • 2642539356 scopus 로고    scopus 로고
    • Microencapsulation of superoxide dismutase into biodegradable microparticles by spray-drying
    • May-Jun
    • Youan BB. Microencapsulation of superoxide dismutase into biodegradable microparticles by spray-drying. Drug Deliv 2004 May-Jun; 11 (3): 209-14
    • (2004) Drug Deliv , vol.11 , Issue.3 , pp. 209-14
    • Youan, B.B.1
  • 149
    • 0037768717 scopus 로고    scopus 로고
    • Poly(lactide-co-glycolide) microspheres containing bupivacaine: Comparison between gamma and beta irradiation effects
    • Jul 31
    • Montanari L, Cilurzo F, Selmin F, et al. Poly(lactide-co-glycolide) microspheres containing bupivacaine: comparison between gamma and beta irradiation effects. J Control Release 2003 Jul 31; 90 (3): 281-90
    • (2003) J Control Release , vol.90 , Issue.3 , pp. 281-90
    • Montanari, L.1    Cilurzo, F.2    Selmin, F.3
  • 150
    • 0037224140 scopus 로고    scopus 로고
    • Etanidazole-loaded microspheres fabricated by spraydrying different poly(lactide/glycolide) polymers: Effects on microsphere properties
    • Wang FJ, Wang CH. Etanidazole-loaded microspheres fabricated by spraydrying different poly(lactide/glycolide) polymers: effects on microsphere properties. J Biomater Sci Polym Ed 2003; 14 (2): 157-83
    • (2003) J Biomater Sci Polym Ed , vol.14 , Issue.2 , pp. 157-83
    • Wang, F.J.1    Wang, C.H.2
  • 151
    • 0342656967 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of a somatostatin analogue released from PLGA microspheres
    • Jun 15
    • Blanco-Prieto MJ, Besseghir K, Zerbe O, et al. In vitro and in vivo evaluation of a somatostatin analogue released from PLGA microspheres. J Control Release 2000 Jun 15; 67 (1): 19-28
    • (2000) J Control Release , vol.67 , Issue.1 , pp. 19-28
    • Blanco-Prieto, M.J.1    Besseghir, K.2    Zerbe, O.3
  • 152
    • 2542509770 scopus 로고    scopus 로고
    • Importance of the test medium for the release kinetics of a somatostatin analogue from poly-(D,L-lactide-co-glycolide) microspheres
    • Jul 20
    • Blanco-Prieto MJ, Besseghir K, Orsolini P, et al. Importance of the test medium for the release kinetics of a somatostatin analogue from poly-(D,L-lactide-co-glycolide) microspheres. Int J Pharm 1999 Jul 20; 184 (2): 243-50
    • (1999) Int J Pharm , vol.184 , Issue.2 , pp. 243-50
    • Blanco-Prieto, M.J.1    Besseghir, K.2    Orsolini, P.3
  • 153
    • 0031757305 scopus 로고    scopus 로고
    • Comparative study of 'in vitro' release of anti-inflammatory drugs from polylactide-co-glycolide micro-spheres
    • Castelli F, Conti B, Maccarrone DE, et al. Comparative study of 'in vitro' release of anti-inflammatory drugs from polylactide-co-glycolide micro-spheres. Int J Pharm 1998; 176 (1): 85-98
    • (1998) Int J Pharm , vol.176 , Issue.1 , pp. 85-98
    • Castelli, F.1    Conti, B.2    Maccarrone, D.E.3
  • 154
    • 0032737783 scopus 로고    scopus 로고
    • Chitosan microspheres: Modification of polymeric chem-physical properties of spray-dried microspheres to control the release of antibiotic drug
    • Mi F, Wong T, Shyu S, et al. Chitosan microspheres: modification of polymeric chem-physical properties of spray-dried microspheres to control the release of antibiotic drug. J Appl Polym Sci 1999; 71 (5): 747-59
    • (1999) J Appl Polym Sci , vol.71 , Issue.5 , pp. 747-59
    • Mi, F.1    Wong, T.2    Shyu, S.3
  • 155
    • 0030604683 scopus 로고    scopus 로고
    • Release ofdiltiazem from Eudragit microparticles prepared by spray-drying
    • KristmundsdottirT, Gudmundsson OS, Ingvarsdottir K. Release ofdiltiazem from Eudragit microparticles prepared by spray-drying. Int J Pharm 1996; 137 (2): 159-65
    • (1996) Int J Pharm , vol.137 , Issue.2 , pp. 159-65
    • Kristmundsdottir, T.1    Gudmundsson, O.S.2    Ingvarsdottir, K.3
  • 156
    • 0028307671 scopus 로고
    • Spray-dried albumin microspheres for the intra-articular delivery of dexamethasone
    • Jul-Aug
    • Pavanetto F, Genta I, Giunchedi P, et al. Spray-dried albumin microspheres for the intra-articular delivery of dexamethasone. J Microencapsul 1994 Jul-Aug; 11 (4): 445-54
    • (1994) J Microencapsul , vol.11 , Issue.4 , pp. 445-54
    • Pavanetto, F.1    Genta, I.2    Giunchedi, P.3
  • 157
    • 0027373002 scopus 로고
    • Evaluation of spray drying as a method for polylactide and polylactide-co-glycolide microsphere preparation
    • Oct-Dec
    • Pavanetto F, Genta I, Giunchedi P, et al. Evaluation of spray drying as a method for polylactide and polylactide-co-glycolide microsphere preparation. J Microencapsul 1993 Oct-Dec; 10 (4): 487-97
    • (1993) J Microencapsul , vol.10 , Issue.4 , pp. 487-97
    • Pavanetto, F.1    Genta, I.2    Giunchedi, P.3
  • 159
    • 0038784350 scopus 로고    scopus 로고
    • Encapsulation of plasmid DNA in PLGA-stearylamine microspheres: A comparison of solvent evaporation and spray-drying methods
    • May-Jun
    • Atuah KN, Walter E, Merkle HP, et al. Encapsulation of plasmid DNA in PLGA-stearylamine microspheres: a comparison of solvent evaporation and spray-drying methods. J Microencapsul 2003 May-Jun; 20 (3): 387-99
    • (2003) J Microencapsul , vol.20 , Issue.3 , pp. 387-99
    • Atuah, K.N.1    Walter, E.2    Merkle, H.P.3
  • 160
    • 70449558745 scopus 로고    scopus 로고
    • Formulation and in vitro characterization of spray-dried antisense oligonucleotide to NF-kappaB encapsulated albumin microspheres
    • Dec
    • Gayakwad SG, Bejugam NK, Akhavein N, et al. Formulation and in vitro characterization of spray-dried antisense oligonucleotide to NF-kappaB encapsulated albumin microspheres. J Microencapsul 2009 Dec; 26 (8): 692-700
    • (2009) J Microencapsul , vol.26 , Issue.8 , pp. 692-700
    • Gayakwad, S.G.1    Bejugam, N.K.2    Akhavein, N.3
  • 161
    • 22244459855 scopus 로고    scopus 로고
    • Comparative study of DNA encapsulation into PLGA microparticles using modified double emulsion methods and spray drying techniques
    • May
    • Oster CG, Kissel T. Comparative study of DNA encapsulation into PLGA microparticles using modified double emulsion methods and spray drying techniques. J Microencapsul 2005 May; 22 (3): 235-44
    • (2005) J Microencapsul , vol.22 , Issue.3 , pp. 235-44
    • Oster, C.G.1    Kissel, T.2
  • 162
    • 0842325074 scopus 로고    scopus 로고
    • Cationic stearylaminecontaining biodegradable microparticles for DNA delivery
    • Feb
    • Kusonwiriyawong C, Atuah K, Alpar OH, et al. Cationic stearylaminecontaining biodegradable microparticles for DNA delivery.J Microencapsul 2004 Feb; 21 (1): 25-36
    • (2004) J Microencapsul , vol.21 , Issue.1 , pp. 25-36
    • Kusonwiriyawong, C.1    Atuah, K.2    Alpar, O.H.3
  • 163
    • 0035845758 scopus 로고    scopus 로고
    • Hydrophilic poly(DL-lactide-co-glycolide) microspheres for the delivery of DNA to human-derived macrophages and dendritic cells
    • Sep 11
    • Walter E, Dreher D, Kok M, et al. Hydrophilic poly(DL-lactide-co- glycolide) microspheres for the delivery of DNA to human-derived macrophages and dendritic cells. J Control Release 2001 Sep 11; 76 (1-2): 149-68
    • (2001) J Control Release , vol.76 , Issue.1-2 , pp. 149-68
    • Walter, E.1    Dreher, D.2    Kok, M.3
  • 164
    • 0141798534 scopus 로고    scopus 로고
    • Statistical modeling of protein spray drying at the lab scale
    • Prinn KB, Costantino HR, Tracy M. Statistical modeling of protein spray drying at the lab scale. AAPS PharmSciTech 2002; 3 (1): E4
    • (2002) AAPS PharmSciTech , vol.3 , Issue.1
    • Prinn, K.B.1    Costantino, H.R.2    Tracy, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.