Importance of the test medium for the release kinetics of a somatostatin analogue from poly(D,L-lactide-co-glycolide) microspheres

International Journal of Pharmaceutics

Volumn 184, Issue 2, 1999, Pages 243-250

  Blanco Príeto, María J ^a   Besseghir, Kamel ^b   Orsolini, Piero ^b   Heimgartner, Frédéric ^b   Deuschel, Christine ^b   Merkle, Hans P ^a   Nam Trân, Hô ^c   Gander, Bruno ^a  

^a ETH ZURICH   (Switzerland)

^b DEBIOPHARM SA   (Switzerland)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Microencapsulation; Microspheres; Poly(D,L lactide co glycolide); Release kinetics; Solubility; Somatostatin analogue; Stability

Indexed keywords

MICROSPHERE; POLYGLACTIN; SOMATOSTATIN DERIVATIVE; VAPREOTIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAMUSCULAR DRUG ADMINISTRATION; KINETICS; MALE; MICROENCAPSULATION; NONHUMAN; PH; PHARMACOKINETICS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG COMPOUNDING; DRUG STABILITY; HORMONE ANTAGONISTS; KINETICS; LACTIC ACID; MALE; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SOLUTIONS; SOMATOSTATIN;

EID: 2542509770     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00118-0     Document Type: Article

References (26)

1. Blanco-Príeto M.J., Leo E., Delie F., Gulik A., Couvreur P., Fattal E. Study of the influence of several stabilizing agents on the entrapment and in vitro release of pBC 264 from poly(lactide-co-glycolide) microspheres prepared by a W/O/W solvent evaporation method. Pharm. Res. 13:1996;1127-1129.
2. Blanco-Príeto M.J., Fattal E., Gulik A., Dedieu J.C., Roques B.P., Couvreur P. Characterization and morphological analysis of a cholecystokinin derivative peptide-loaded poly(lactide-co-glycolide) microspheres prepared by a water-in-oil-in-water emulsion solvent evaporation method. J. Control. Release. 43:1997;81-87.
3. Blanco-Príeto, M.J., Nam-Trân, Hô, Ngûyen, V.P., Orsolini, P., Besseghir, K., Merkle, H.P., Gander, B., 1998. Thermodynamic parameters for microencapsulation of an octapeptide into PLA/PLGA microspheres. Proceedings of the 2nd World Meeting APGI/APV, Paris, pp. 521-522.
4. Bodmer D., Kissel T., Traechslin E. Factors influencing the release of peptides and proteins from biodegradable depot systems. J. Control. Release. 21:1992;129-138.
5. Conti B., Genta I., Giunchedi P., Modena T. Testing of in vitro dissolution behaviour of microparticulate drug delivery systems. Drug Dev. Ind. Pharm. 21:1995;1223-1233.
6. Gido C., Langguth P., Mutschler E. Predictions of in vivo plasma concentrations from in vitro release kinetics: application to doxepin parenteral (i. m.) suspensions in lipophilic vehicles in dogs. Pharm. Res. 11:1994;800-808.
7. Hashimoto T., Wada T., Fukuda N., Nagaoka A. Effect of thyrotropin-releasing hormone on pentobarbitone-induced sleep in rats: continous treatment with a sustained release injectable formulation. J. Pharm. Pharmacol. 45:1993;94-97.
8. Heya T., Okada H., Ogawa Y., Toguchi H. Factors influencing the profils of TRH release from copoly(D,L-lactic/glycolic acid) microspheres. Int. J. Pharm. 72:1991;199-205.
9. Heya T., Okada H., Ogawa Y., Toguchi H. In vitro and in vivo evaluation of thyrotrophin releasing hormone release from copoly(DL-lactic/glycolic acid) microspheres. J. Pharm. Sci. 83(5):1994;636-640.
10. Johansen, P., Corradin, G., Merkle, H.P., Gander, B., 1998. Release of tetanus toxoid from adjuvants and PLGA microspheres: how experimental set-up and surface adsorption fool the pattern. J. Control. Release 56, 209-217.
11. Kissel T., Brich Z., Bantle S., Lancranjan I., Nimmerfall F., Vit P. Parenteral depot-systems on the basis of biodegradable polyesters. J. Control. Release. 16:1991;27-42.
12. Kurono Y., Furukawa A., Takesue Y., Li F., Ikeda K. Photo-stabilization and solubilization of an aldose reducttase inhibitor, (E)-3-Carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene]rhodanine (ONO-2235), by human serum albumin. Chem. Pharm. Bull. 37(7):1987;3045-3048.
13. Lawter J.R., Brizzolara N.S., Lanzilotti M.G., Morton G.O. Drug release from poly(glycolid-co-lactide) microcapsules. Proc. Int. Symp. Control. Release Bioact. Mater. 14:1987;99-100.
14. Manson-Garcia M., Vaccarella M., Horvath J., Redding T.W., Groot K., Orsolini P., Schally A. Radio-immunoassay for octapeptide analogs of somatostatin: measurement of serum levels after administration of long-acting microcapsule formulations. Proc. Natl. Acad. Sci. U.S.A. 85:1988;5688-5692.
15. Miyamoto M., Hirai K., Takahashi H., Kato K., Nishiyama M., okada H., Nagaoka A. Effect of sustained release formulation of thyrotropin-releasing hormone on learning impairment caused by scopolamine and AF64A in rodents. Eur. J. Pharmacol. 238:1993;181-189.
16. Morlock M., Koll H., Winter G., Kissel T. Microencapsulation of rh-erytropoietin, using biodegradable poly(D,L-lactide-co-glycolide): protein stability and the effects of stabilizing excipients. Eur. J. Pharm. Biopharm. 43:1997;29-36.
17. Ogawa Y., Okada H., Heya T., Shimamoto T. Controlled release of LHRH agonist, leuprolide acetate, from microcapsules; serum drug level profiles and pharmacological effects in animals. J. Pharm. Pharmacol. 41:1989;439-444.
18. Okada H., Heya T., Ogawa Y., Shimamoto T. One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. J. Pharm. Exp. Ther. 244:1988;744-749.
19. Okada H., Heya T., Igari Y., Ogawa Y., Toguchi H., Shimamoto T. One-month release injectable microspheres of leuprolide acetate inhibit steroidogenesis and genital organ growth in rats. Int. J. Pharm. 54:1989;231-239.
20. Park T.G., Lu W., Crotts G. Importance of in vitro experimental conditions on protein release kinetics, stability and polymer degradation in protein encapsulated poly(D,L-lactic acid-co-glycolic acid) microspheres. J. Control. Release. 33:1995;211-222.
21. Rothen-Weinhold A., Besseghir K., Gurny R. Analysis of the influence of polymer characteristics and core loading on the in vivo release of a somatostatin analogue. Eur. J. Pharm. Biopharm. 5:1997;303-313.
22. Russel-Jones G.J., Jeffery H. In vitro characterization of biodegradable microparticles for oral antigen delivery. Proc. Int. Symp. Control. Release Bioact. Mater. 21:1994;873-874.
23. Sanders L.M., Kent J.S., McRae G.I., Vickery B.H., Tice T.R., Lewis D.H. Controlled release of luteinizing hormone-releasing hormone analogue from poly(D,L-lactide-co-glycolide) microspheres. J. Pharm. Sci. 73:1984;1294-1297.
24. Stoeckemann K., Sandow J. Effects of the luteinizing-hormone-releasing hormone (LHRH) antagonist ramorelix (Hoe013) and the LHRH agonist buserelin on dimethylbenz(a)anthracene-induced mammary carcinoma: Studies with slow-release formulations. J. Cancer Res. Clin. Oncol. 119:1993;457-462.
25. Thomasin C., Corradin G., Men Y., Merkle H.P., Gander B. Tetanus toxoid and synthetic malaria antigen containing poly(lactide)/poly(lactide-co-glycolide) microspheres: importance of polymer degradation and antigen release for immune response. J. Control. Release. 41:1996;131-145.
26. Yang J., Cleland J.L. Factor affecting the in vitro release of recombinant human interferon-γ (rhINF-γ) from PLGA microspheres. J. Pharm. Sci. 86:1997;980-994.