Hydrophilic poly(DL-lactide-co-glycolide) microspheres for the delivery of DNA to human-derived macrophages and dendritic cells

Journal of Controlled Release

Volumn 76, Issue 1-2, 2001, Pages 149-168

  Walter, Elke ^a   Dreher, Donatus ^b   Kok, Menno ^c   Thiele, Lars ^a   Kiama, Stephen Gitahi ^d   Gehr, Peter ^d   Merkle, Hans Peter ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

Dendritic cells; DNA; Macrophages; Poly(lactide co glycolide) (PLGA) microspheres; Toxicity

Indexed keywords

DNA; MICROSPHERE; POLYGLACTIN; POLYMER; POLYMER R202; POLYMER R202H; POLYMER RG502; POLYMER RG502H; POLYMER RG503; POLYMER RG503H; RESOMER; UNCLASSIFIED DRUG;

ACIDITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DENDRITIC CELL; DNA CONTENT; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; DRUG UPTAKE; GENE TARGETING; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNOMODULATION; MACROPHAGE; MICROENCAPSULATION; MOLECULAR WEIGHT; NORMAL HUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; TRANSPORT KINETICS;

CELLS, CULTURED; DENDRITIC CELLS; DNA; HUMANS; LACTIC ACID; MACROPHAGES; MICROSPHERES; PHAGOCYTOSIS; PLASMIDS; POLYGLYCOLIC ACID; POLYMERS; SOLUBILITY;

EID: 0035845758     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00413-8     Document Type: Article

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