Retained integrity of protein encapsulated in spray-dried chitosan microparticles

Journal of Microencapsulation

Volumn 26, Issue 2, 2009, Pages 111-121

  Kusonwiriyawong, Chirasak ^a,b   Pichayakorn, Wiwat ^a   Lipipun, Vimolmas ^a   Ritthidej, Garnpimol C ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b RANGSIT UNIVERSITY   (Thailand)

Author keywords

Bovine serum albumin; Chitosan; Integrity; Microparticles; Protein; Spray dry

Indexed keywords

BOVINE SERUM ALBUMIN; CHITOSAN;

AIR TEMPERATURE; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; MICROENCAPSULATION; MOLECULAR WEIGHT; PARTICLE SIZE; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; SPRAY DRYING; ZETA POTENTIAL;

ANIMALS; CAPSULES; CATTLE; CHEMISTRY, PHYSICAL; CHITOSAN; CIRCULAR DICHROISM; DRUG COMPOUNDING; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MOLECULAR WEIGHT; PARTICLE SIZE; PROTEINS; SERUM ALBUMIN, BOVINE; TEMPERATURE; TIME FACTORS;

EID: 58149473078     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/02652040802190937     Document Type: Article

References (40)

1. Adler, M. and Lee, G. (1999) Stability and surface activity of lactate dehydrogenase in spray-dried trehalose. J Pharm Sci, 88, pp. 199-208.
2. Ameri, M. and Maa, YF (2006) Spray drying of biopharmaceuticals: Stability and process considerations. Drying Technol, 24, pp. 763-768.
3. Blanco, D. and Alonso, MJ (1997) Development and characterization of protein-loaded poly(lactide-co-glycolide) nanospheres. Eur J Pharm Biopharm, 43, pp. 287-294.
4. Blanco-Prieto, MJ, Campanero, MA, Besseghir, K., Heimgatner, F. and Gander, B. (2004) Importance of single or blended polymer types for controlled in vitro release and plasma levels of a somatostatin analogue entrapped in PLA/PLGA microspheres. J Contr Rel, 96, pp. 437-448.
5. Bosquillon, C., Lombry, C., Preat, V. and Vanbever, R. (2001) Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance. J Contr Rel, 70, pp. 329-339.
6. Broadhead, J., Rouan, SKE, Hau, I. and Rhodes, C. (1994) The effect of process and formulation variables on the properties of spray dried β-galactosidase. J Pharm Pharmacol, 46, pp. 458-467.
7. Broadhead, J., Rouan, SKE and Rhodes, CT (1992) The spray drying of pharmaceuticals. Drug Dev Ind Pharm, 18, pp. 1169-1206.
8. Cegnar, M., Kos, J. and Kristl, J. (2004) Cystatin incorporated in poly(lactide-co-glycolide) nanoparticles: Development and fundamental studies on preservation of its activity. Eur J Pharm Sci, 22, pp. 357-364.
9. Costantino, HR, Johnson, OL and Zale, SE (2004) Relationship between encapsulated drug particle size and initial release of recombinant human growth hormone from biodegradable microspheres. J Pharm Sci, 93, pp. 2624-2634.
10. Faldt, P. and Bergenståhl, B. (1994) The surface composition of spray-dried protein-lactose powders. Colloids Surf A: Physicochem Eng Aspects, 90, pp. 183-190.
11. Griebenow, K. and Klibanov, AM (1995) Lyophilization-induced reversible changes in the secondary structure of proteins. Proc Natl Acad Sci USA, 92, pp. 10969-10976.
12. He, P., Davis, SS and Illum, L. (1999) Chitosan microparticles prepared by spray drying. Int J Pharm, 187, pp. 53-65.
13. Illum, L. (1998) Chitosan and its use as a pharmaceutical excipient. Pharm Res, 15, pp. 1326-1331.
14. Kelly, SM and Price, NC (1997) The application of circular dichroism to studies of protein folding and unfolding. Biochim Biophys Acta, 1338, pp. 161-185.
15. Kim, JH and Bae, YH (2004) Albumin loaded microsphere of amphiphilic poly(ethylene glycol)/poly(alpha-ester) multiblock copolymer. Eur J Pharm Sci, 23, pp. 245-251.
16. Labrude, P., Rasolomanana, M., Vigneron, C., Thirion, C. and Chaillot, B. (1989) Protective effect of sucrose on spray drying of oxyhemoglobin. J Pharm Sci, 78, pp. 223-229.
17. Landstrom, K., Bergenståhl, B., Alsins, J. and Almgren, M. (1999) A fluorescence method for quantitative measurements of specific protein at powder surfaces. Colloids Surf B Biointerfaces, 12, pp. 429-440.
18. Lee, G. (2002) Spray-drying of proteins. Rational design of stable protein formulations: Theory and practice, pp. 135-158. Kluwer, New York
19. Maa, YF and Hsu, CC (1996) Effect of high shear on proteins. Biotechnol Bioeng, 51, pp. 458-465.
20. Maa, YF and Hsu, CC (1997) Protein denaturation by combined effect of shear and air-liquid interface. Biotechnol Bioeng, 54, pp. 503-512.
21. Maa, YF, Nguyen, PT and Hsu, SW (1998) Spray-drying of air-liquid interface sensitive recombinant human growth hormone. J Pharm Sci, 87, pp. 152-159.
22. Malamud, D. and Drysdale, JW (1978) Isoelectric points of proteins: A table. Anal Biochem, 86, pp. 620-647.
23. Mi, FL, Tan, YC, Liang, HF and Sung, HW (2002) In vivo biocompatibility and degradability of a novel injectable-chitosan-based implant. Biomaterials, 23, pp. 181-191.
24. Millqvist-Fureby, A., Malmsten, M. and Bergenståhl, B. (1999) Spray-drying of trypsin-surface characterization and activity preservation. Int J Pharm, 188, pp. 243-253.
25. Mumenthaler, M., Hsu, CC and Pearlman, R. (1994) Feasibility study on spray-drying protein pharmaceuticals: Recombinant human growth hormone and tissue-type plasminogen activator. Pharm Res, 11, pp. 12-20.
26. Pelton, JT and McLean, LR (2000) Spectroscopic methods for analysis of protein secondary structure. Anal Biochem, 277, pp. 167-176.
27. Prestrelski, S., Tedeschi, N., Arakawa, T. and Carpenter, JF (1993) Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers. Biophys J, 65, pp. 661-671.
28. Righetti, PG and Caravaggio, T. (1976) Isoelectric points and molecular weights of proteins: A table. J Chromatog A, 127, pp. 1-28.
29. Sinha, VR, Bansal, K., Kaushik, R., Kumria, R. and Trehan, A. (2004) Poly-epsilon-caprolactone microspheres and nanospheres: An overview. Int J Pharm, 278, pp. 1-23.
30. Sreerama, N. and Woody, RW (2000) Circular dichroism of peptides and proteins. Circular dichroism: Principles and applications, pp. 601-620. Wiley-VCH, New York
31. Ståhl, K., Claesson, M., Lilliehorn, P., Linden, H. and Backstrom, K. (2002) The effect of process variables on the degradation and physical properties of spray dried insulin intended for inhalation. Int J Pharm, 233, pp. 227-237.
32. Tobio, M., Gref, R., Sanchez, A., Langer, R. and Alonso, MJ (1998) Stealth PLA-PEG nanoparticles as protein carriers for nasal administration. Pharm Res, 15, pp. 270-275.
33. Tzannis, ST and Prestrelski, SJ (1999) Activity-stability considerations of trypsinogen during spray drying: Effects of sucrose. J Pharm Sci, 88, pp. 351-359.
34. van de Weert, M., Hoechstetter, J., Hennink, WE and Crommelin, DJA (2000) The effect of a water/organic solvent interface on the structural stability of lysozyme. J Contr Rel, 68, pp. 351-359.
35. Vanbever, R., Mintzes, JD, Wang, J., Nice, J., Chen, D., Batycky, R., Langer, R. and Edwards, DA (1999) Formulation and physical characterization of large porous particles for inhalation. Pharm Res, 16, pp. 1735-1742.
36. Walsh, G. (2005) Biopharmaceuticals: Recent approvals and likely directions. Trends Biotechnol, 23, pp. 553-558.
37. Winters, MA, Knutson, BL, Debenedetti, PG, Sparks, HG, Przybycien, TM, Stevenson, CL and Prestrelski, SJ (1996) Precipitation of proteins in supercritical carbon dioxide. J Pharm Sci, 85, pp. 586-594.
38. Xu, YM and Du, YM (2003) Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles. Int J Pharm, 250, pp. 215-226.
39. Youan, BC (2004) Microencapsulation of superoxide dismutase into biodegradable microparticles by spray-drying. Drug Del, 11, pp. 209-214.
40. Zimmerman, I. (1997) Possibilities and limitations of laser light scattering techniques for particle size analysis. Particle and surface characterization methods, pp. 19-26. Stuttgart, Medpharm