Generation of reactive oxygen species by the mitochondrial electron transport chain

Journal of Neurochemistry

Volumn 80, Issue 5, 2002, Pages 780-787

  Liu, Yuanbin ^a   Fiskum, Gary ^b   Schubert, David ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Electron transport chain; Mitochondria; Parkinson's disease; Reactive oxygen species

Indexed keywords

FLAVINE MONONUCLEOTIDE; HYDROGEN PEROXIDE; PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUCCINIC ACID; SUPEROXIDE; UBIQUINONE;

AGING; ANIMAL TISSUE; ARTICLE; ELECTRON TRANSPORT; FLUORESCENCE; MITOCHONDRION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; BRAIN CHEMISTRY; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX III; FLAVIN MONONUCLEOTIDE; HYDROGEN PEROXIDE; MITOCHONDRIA; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION; RATS; REACTIVE OXYGEN SPECIES; SUBCELLULAR FRACTIONS; UBIQUINONE;

ANIMALIA;

EID: 0036319021     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-3042.2002.00744.x     Document Type: Article

References (32)

1. Chronic systemic pesticide exposure reproduces features of Parkinson's disease
2. Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria
3. Mitochondrial production of superoxide anions and its relationship to antimycin insensitive respiration
4. Cellular production of hydrogen peroxide
5. Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria
6. The interaction of energy and electron transfer reactions in mitochondria. I. General properties and nature of the products of succinate-linked reduction of pyridine nucleotide
7. The interaction of energy and electron transfer reactions in mitochondria. IV. The pathway of electron transfer
8. Hydroperoxide metabolism in mammlian organs
9. Generation of hydrogen peroxide by brain mitochondria: The effect of reoxygenation following postdecapitative ischemia
10. The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labeling of a component polypeptide of the oxidase
11. On the virtual existence of superoxide anions in mitochondria: Thoughts regarding its role in pathophysiology
12. New substrates for the fluorometric determination of oxidative enzymes
13. Partial resolution of the enzymes catalyzing oxidative phosphorylation. XV. Reverse electron transfer in the flavin-cytochrome b region of the respiratory chain of beef heart submitochondrial particles
14. Mechanism of action of the hypoglycemic agent diphenyleneiodonium
15. Properties of mitochondria treated with 1-chloro-2,4-dinitrobenzene
16. Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria
17. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial dismutase-deficient mice
18. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
19. 2 release by isolated brain mitochondria in a canine cerebral ischemia/reperfusion model
20. Respiratory chain linked production in pigeon heart mitochondria
21. Superoxide radicals as precursors of mitochondrial hydrogen peroxide
22. Specific labelling of a constituent polypeptide of bovine heart mitochondrial reduced nicotinamideadenine dinucleotide-ubiquinone reductase by the inhibitor diphenyleneiodonium
23. Human complex I deficiency: Clinical spectrum and involvement of oxygen free radicals in the pathogenicity of the defect
24. Oxidative damage and mitochondrial decay in aging
25. The regulation of reactive oxygen species production during programmed cell death
26. Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria
27. Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
28. The preparation of heart mitochondria from laboratory animals
29. δψm-dependent and -independent production of reactive oxygen species by rat brain mitochondria
30. Mitochondrial diseases in man and mouse
31. Thermodynamic relationships in mitochondrial oxidative phosphorylation
32. Pathways of hydrogen peroxide generation in guinea pig cerebral cortex mitochondria