Oxidative stress is associated with region-specific neuronal death during thiamine deficiency

Journal of Neuropathology and Experimental Neurology

Volumn 58, Issue 9, 1999, Pages 946-958

  Calingasan, Noel Y ^a   Chun, William J ^a   Park, Larry C H ^a   Uchida, Koji ^b   Gibson, Gary E ^a,c  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NAGOYA UNIVERSITY   (Japan)

^c BURKE MEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

4 Hydroxynonenal; Heine oxygenase 1; Lipid peroxidation; Neurodegeneration; Nitric oxide; Oxidative stress; Thiamine

Indexed keywords

4 HYDROXYNONENAL; HEME OXYGENASE; NITRIC OXIDE SYNTHASE;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENZYME ACTIVITY; LIPID PEROXIDATION; MACROPHAGE; MALE; MICROGLIA; MODEL; MOUSE; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; THALAMUS; THIAMINE DEFICIENCY;

EID: 0032849357     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199909000-00005     Document Type: Article

References (53)

1. Blass JP, Gibson GE. The role of oxidative abnormalities in the pathophysiology of Alzheimer disease. Rev Neurol 1991;147:513-25
2. Smith CD, Carney JM, Starke-Reed PE, Oliver CN, et al. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer Disease. Proc Natl Acad Sci USA 1991;88: 10540-43
3. Hensley K, Carney JM, Mattson MP, el al. A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer Disease. Proc Natl Acad Sci USA 1994;91:3270-74
4. Nixon RA, Cataldo AM. Free radicals, proteolysis and degeneration of neurons in Alzheimer Disease: How essential is the β-amyloid link? Neurobiol Aging 1994;15:463-69
5. Smith MA, Perry G. Free radical damage, iron, and Alzheimer disease. J Neurol Sci 1995;134:92-94
6. Smith MA, Sayre LM, Monnier VM, Perry G. Radical AGEing in Alzheimer Disease. Trends Neurosci 1995;18:172-76
7. Dexter DT, Carter CJ, Wells FR, Javoy-Agid F, Jenner P, Marsden CD. Basal lipid peroxidation in substantia nigra is increased in Parkinson Disease. J Neurochem 1987;52:381-89
8. Beal MF. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 1995;38:357-66
9. Furuta A, Price DL, Pardo CA, et al. Localization of superoxide dismutases in Alzheimer disease and Down syndrome neocortex and hippocampus. Am J Pathol 1995;146:357-67
10. Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993;362:59
11. Gibson GE, Ksiezak-Reding H, Sheu K-FR, Mykytyn V, Blass JP. Correlation of enzymatic, metabolic and behavioral deficits in thiamine deficiency and its reversal. Neurochem Res 1984;9:803-14
12. Butterworth RF. Cerebral thiamine-dependent enzyme changes in experimental Wernicke's encephalopathy. Metab Brain Dis 1986;1: 165-75
13. Calingasan NY, Baker H, Sheu K-FR, Gibson GE. Blood-brain abnormalities in vulnerable brain regions during thiamine deficiency. Exp Neurol 1995;134:64-72
14. Harata N, Iwasaki Y. Evidence for early blood-brain barrier breakdown in experimental thiamine deficiency in the mouse. Metab Brain Dis 1995;10:159-74
15. Calingasan NY, Park LCH, Calo LL, Trifiletti RR, Gandy SE, Gibson GE. Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism. Am J Pathol 1998;153:1381-98
16. Todd KG, Butterworth RF. Early microglial response in experimental thiamine deficiency: An immunohistochemical analysis. Glia 1999;25:190-98
17. Sandau K, Pfeilschifter J, Brune B. Nitrosative and oxidative stress induced heme oxygenase-1 accumulation in rat mesangial cells. Eur J Pharmacol 1998;342:77-84
18. Maines, M. D. Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 1988;2:2557-68
19. Stocker R, Yamamoto Y, McDonagh AF, Glazer AN, Ames BN. Bilirubin is an antioxidant of possible physiological importance. Science 1987;235:1043-46
20. Smith MA, Kutty RK, Richey PL, et al. Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease. Am J Pathol 1994;145:42-47
21. Applegate L, Luscher P, Tyrrell R. Induction of heme oxygenase: A general response to oxidant stress in cultured mammalian cells. Cancer Res 1991;51:974-78
22. Ewing JF, Haber SN, Maines MD. Normal and heat-induced patterns of expression of heme oxygenase-1(HSP32) in rat brain: Hyperthermia causes rapid induction of mRNA and protein. J Neurochem 1992;58:1140-49
23. Kutty RK, Kutty G, Wiggert B, Chader GJ, Darrow RM, Organisciak DT. Induction of heme oxygenase 1 in the retina by intense visible light: Suppression by the antioxidant dimethylthiourea. Proc Natl Acad Sci USA 1995;92:1177-81
24. Shibahara S, Muller RM, Taguchi H. Transcriptional control of rat heme oxygenase by heat shock. J Biol Chem 1987;262:12889-92
25. Kitamura Y, Furukawa M, Matsuoka Y, et al. In vitro and in vivo induction of heme oxygenase-1 in rat glial cells - Possible involvement of nitric oxide production from inducible nitric oxide synthase. Glia 1998;22:138-48
26. Fukuda K, Richmon JD, Sato M, Sharp FR, Panter SS, Noble LJ. Induction of heme oxygenase-1 (HO-1) in glia after traumatic brain injury. Brain Res 1996;736:68-75
27. Matsuoka Y, Kitamura Y, Okazaki M, Sakata M, Tsukuhara T, Taniguchi T. Induction of heme oxygenase-1 and major histocompatibility complex antigens in transient forebrain ischemia. J Cereb Blood Flow Met 1998;18:824-32
28. Takizawa S, Hirabayashi H, Matsushima K, Tokuoka K, Shinohara Y. Induction of heme oxygenase protein protects neurons in cortex and striatum, but not in hippocampus, against transient forebrain ischemia. J Cereb Blood Flow Met 1998;18:559-69
29. Bergeron M, Ferriero DM, Vreman HJ, Stevenson DK, Sharp FR. Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1 (HSP32) in newborn rat brain. J Cereb Blood Flow Met 1997;17:647-58
30. Schipper HM, Cissé S, Stopa EG. Expression of heme oxygenase-1 in the senescent and Alzheimer disease brain. Ann Neurol 1995;37: 758-68
31. Schipper HM, Liberman A, Stopa EG. Neural heme oxygenase-1 expression in idiopathic Parkinson's disease. Exp Neurol 1998;150: 60-68
32. Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radical Biol Med 1991;11:81-128
33. Basu-Modak S, Luscher P and Tyrrell RM. Lipid metabolite involvement in the activation of the human heme oxygenase-1 gene. Free Radical Biol Med 1996;20:887-97
34. Yoritaka A, Hattori N, Uchida K, Tanaka M, Stadtman ER. Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson's disease. Proc Natl Acad Sci USA 1996;93:2696-701
35. Sayre LM, Zolaesque DA, Harris PL, Perry G, Salomon RK, Smith MA. 4-hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem 1997;68:2092-97
36. Hsu S, Raine L, Fanger H. Use of avidin-biotin-peroxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981;29:577-80
37. Mullen RJ, Buck CR, Smith AM. NeuN, a neuronal specific nuclear protein in vertebrates. Development 1992;116:201-11
38. Schmidt-Kastner R, Meller D, Bellander B-M, Stromberg I, Olson L, Ingvar M. A one-step immunohistochemical method for detection of blood-brain barrier disturbances for immunoglobulins in lesioned rat brain with special reference to false positive labelling in immunohistochemistry. J Neurosci Methods 1993;46:121-32
39. Franklin KBJ, Paxinos G. The mouse brain in stereotaxic coordinates. San Diego: Academic Press, 1996
40. Langlais PJ, Anderson G, Guo SX, Bondy SC. Increased cerebral free radical production during thiamine deficiency. Metab Brain Dis 1997;12:137-43
41. Keyse SM, Tyrrell RM. Heme oxygenase is the major 32 kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide and sodium arsenite. Proc Natl Acad Sci USA 1989;86:99-103
42. Keyse SM, Applegate LA, Tromvoukis Y, Tyrrell RM. Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts. Mol Cell Biol 1990;10: 4967-69
43. Tyrrell RM, Applegate LA, Tromvoukis Y. The proximal promoter region of the human heme oxygenase gene contains elements involved in stimulation of transcriptional activity by a variety of agents including oxidants. Carcinogenesis 1993;14:761-65
44. Vile GF, Basu-Modak S, Waltner C, Tyrrell RM. Heme oxygenase-1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proc Natl Acad Sci USA 1994;91:2607-10
45. Wagener FE, de Witte T, Abraham NG. Heme induces the expression of adhesion molecules ICAM-1, VCAM-1, and E selectin in vascular endothelial cells. Proc Soc Exp Biol Med 1997;216:456-63
46. Richmon JD, Fukuda K, Maida N, et al. Induction of heme oxygenase-1 after hyperosmotic opening of the blood-brain barrier. Brain Res 1998;780:108-18
47. Amit J, Zhining D. Age-dependent sensitivity of cultured rat glial cells to bilirubin toxicity. Exp Neurol 1993;121:248-55
48. Braughler JM, Duncan LA, Chase RL. The involvement of iron and lipid peroxidation. Importance of ferric to ferrous ratios in initiation. J Biol Chem 1986;261:10282-89
49. Springer JE, Azbill RD, Mark RJ, Begley JG, Waeg G, Mattson MP. 4-Hydroxynonenal, a lipid peroxidation product, rapidly accumulates following traumatic spinal cord injury and inhibits glutamate uptake. J Neurochem 1997;68:2469-76
50. Langlais PJ, Mair RK. Protective effects of the glutamate antagonist MK-801 on pyrithiamine-induced lesions and amino acid changes in rat brain. J Neurosci 1990;10:1664-74
51. Zhang SX, Weilersbacher GS, Henderson SW, Corso T, Olney JW, Langlais PJ. Excitotoxic cytopathology, progression, and reversibility of thiamine deficiency-induced diencephalic lesions. J Neuropathol Exp Neurol 1995;54:255-67
52. Reif DW. Ferritin as a source of iron for oxidative damage. Free Radical Biol Med 1992;12:417-27
53. Yoshida T, Tanaka M, Sotomatsu A, Hirai S, Okamoto K. Activated microglia cause iron-dependent lipid peroxidation in the presence of ferritin. Neuroreport 1998;9:1929-33