-
2
-
-
0013816340
-
Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues
-
Pernis B, Chiappino G, Kelus AS, Gell PG. Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues. J Exp Med 1965 122:853 876.
-
(1965)
J Exp Med
, vol.122
, pp. 853-876
-
-
Pernis, B.1
Chiappino, G.2
Kelus, A.S.3
Gell, P.G.4
-
3
-
-
0035936833
-
Contribution of receptor editing to the antibody repertoire
-
Casellas R, et al. Contribution of receptor editing to the antibody repertoire. Science 2001 291:1541 1544.
-
(2001)
Science
, vol.291
, pp. 1541-1544
-
-
Casellas, R.1
-
4
-
-
0013839509
-
Differential activity of allelic gamma-globulin genes in antibody-producing cells
-
Weiler E. Differential activity of allelic gamma-globulin genes in antibody-producing cells. Proc Natl Acad Sci USA 1965 54:1765 1772.
-
(1965)
Proc Natl Acad Sci USA
, vol.54
, pp. 1765-1772
-
-
Weiler, E.1
-
5
-
-
0034650907
-
Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expressing B cells in mice
-
Barreto V, Cumano A. Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expressing B cells in mice. J Immunol 2000 164:893 899.
-
(2000)
J Immunol
, vol.164
, pp. 893-899
-
-
Barreto, V.1
Cumano, A.2
-
6
-
-
0032007002
-
Precursor B cells showing H chain allelic inclusion display allelic exclusion at the level of pre-B cell receptor surface expression
-
ten Boekel E, Melchers F, Rolink AG. Precursor B cells showing H chain allelic inclusion display allelic exclusion at the level of pre-B cell receptor surface expression. Immunity 1998 8:199 207.
-
(1998)
Immunity
, vol.8
, pp. 199-207
-
-
Ten Boekel, E.1
Melchers, F.2
Rolink, A.G.3
-
7
-
-
0030888193
-
B cell development under the condition of allelic inclusion
-
Sonoda E, et al. B cell development under the condition of allelic inclusion. Immunity 1997 6:225 233.
-
(1997)
Immunity
, vol.6
, pp. 225-233
-
-
Sonoda, E.1
-
8
-
-
0033918082
-
Mutually exclusive expression of odorant receptor transgenes
-
Serizawa S, et al. Mutually exclusive expression of odorant receptor transgenes. Nat Neurosci 2000 3:687 693.
-
(2000)
Nat Neurosci
, vol.3
, pp. 687-693
-
-
Serizawa, S.1
-
9
-
-
0027981484
-
Allelic inactivation regulates olfactory receptor gene expression
-
Chess A, Simon I, Cedar H, Axel R. Allelic inactivation regulates olfactory receptor gene expression. Cell 1994 78:823 834.
-
(1994)
Cell
, vol.78
, pp. 823-834
-
-
Chess, A.1
Simon, I.2
Cedar, H.3
Axel, R.4
-
10
-
-
0032142799
-
Regulation of IL-4 expression by activation of individual alleles
-
Riviere I, Sunshine MJ, Littman DR. Regulation of IL-4 expression by activation of individual alleles. Immunity 1998 9:217 228.
-
(1998)
Immunity
, vol.9
, pp. 217-228
-
-
Riviere, I.1
Sunshine, M.J.2
Littman, D.R.3
-
11
-
-
0028980998
-
Allelic exclusion of Ly49-family genes encoding class i MHC-specific receptors on NK cells
-
Held W, Roland J, Raulet DH. Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells. Nature 1995 376:355 358.
-
(1995)
Nature
, vol.376
, pp. 355-358
-
-
Held, W.1
Roland, J.2
Raulet, D.H.3
-
12
-
-
0038731119
-
Monoallelic expression of the murine gene encoding Toll-like receptor 4
-
Pereira JP, Girard R, Chaby R, Cumano A, Vieira P. Monoallelic expression of the murine gene encoding Toll-like receptor 4. Nat Immunol 2003 4:464 470.
-
(2003)
Nat Immunol
, vol.4
, pp. 464-470
-
-
Pereira, J.P.1
Girard, R.2
Chaby, R.3
Cumano, A.4
Vieira, P.5
-
13
-
-
0025809321
-
Parental imprinting of the mouse H19 gene
-
Bartolomei MS, Zemel S, Tilghman SM. Parental imprinting of the mouse H19 gene. Nature 1991 351:153 155.
-
(1991)
Nature
, vol.351
, pp. 153-155
-
-
Bartolomei, M.S.1
Zemel, S.2
Tilghman, S.M.3
-
14
-
-
0025967857
-
Parental imprinting of the mouse insulin-like growth factor II gene
-
DeChiara TM, Robertson EJ, Efstratiadis A. Parental imprinting of the mouse insulin-like growth factor II gene. Cell 1991 64:849 859.
-
(1991)
Cell
, vol.64
, pp. 849-859
-
-
Dechiara, T.M.1
Robertson, E.J.2
Efstratiadis, A.3
-
16
-
-
0242468050
-
Regulating antigen-receptor gene assembly
-
Schlissel MS. Regulating antigen-receptor gene assembly. Nat Rev Immunol 2003 3:890 899.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 890-899
-
-
Schlissel, M.S.1
-
17
-
-
0021983551
-
Developmentally controlled and tissue-specific expression of unrearranged VH gene segments
-
Yancopoulos GD, Alt FW. Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell 1985 40:271 281.
-
(1985)
Cell
, vol.40
, pp. 271-281
-
-
Yancopoulos, G.D.1
Alt, F.W.2
-
18
-
-
0029894165
-
Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
-
Stanhope-Baker P, Hudson KM, Shaffer AL, Constantinescu A, Schlissel MS. Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro. Cell 1996 85:887 897.
-
(1996)
Cell
, vol.85
, pp. 887-897
-
-
Stanhope-Baker, P.1
Hudson, K.M.2
Shaffer, A.L.3
Constantinescu, A.4
Schlissel, M.S.5
-
19
-
-
0021442649
-
Ordered rearrangement of immunoglobulin heavy chain variable region segments
-
Alt FW, et al. Ordered rearrangement of immunoglobulin heavy chain variable region segments. EMBO J 1984 3:1209 1219.
-
(1984)
EMBO J
, vol.3
, pp. 1209-1219
-
-
Alt, F.W.1
-
20
-
-
0028466384
-
Analysis of the B-cell progenitor compartment at the level of single cells
-
Ehlich A, Martin V, Muller W, Rajewsky K. Analysis of the B-cell progenitor compartment at the level of single cells. Curr Biol 1994 4:573 583.
-
(1994)
Curr Biol
, vol.4
, pp. 573-583
-
-
Ehlich, A.1
Martin, V.2
Muller, W.3
Rajewsky, K.4
-
21
-
-
0027476466
-
Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development
-
Ehlich A, Schaal S, Gu H, Kitamura D, Muller W, Rajewsky K. Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development. Cell 1993 72:695 704.
-
(1993)
Cell
, vol.72
, pp. 695-704
-
-
Ehlich, A.1
Schaal, S.2
Gu, H.3
Kitamura, D.4
Muller, W.5
Rajewsky, K.6
-
22
-
-
0029063042
-
The status of Ig loci rearrangements in single cells from different stages of B cell development
-
ten Boekel E, Melchers F, Rolink A. The status of Ig loci rearrangements in single cells from different stages of B cell development. Int Immunol 1995 7:1013 1019.
-
(1995)
Int Immunol
, vol.7
, pp. 1013-1019
-
-
Ten, B.E.1
Melchers, F.2
Rolink, A.3
-
23
-
-
0019846013
-
Organization and reorganization of immunoglobulin genes in A-MULV-transformed cells: Rearrangement of heavy but not light chain genes
-
Alt F, Rosenberg N, Lewis S, Thomas E, Baltimore D. Organization and reorganization of immunoglobulin genes in A-MULV-transformed cells: rearrangement of heavy but not light chain genes. Cell 1981 27:381 390.
-
(1981)
Cell
, vol.27
, pp. 381-390
-
-
Alt, F.1
Rosenberg, N.2
Lewis, S.3
Thomas, E.4
Baltimore, D.5
-
24
-
-
0028784187
-
Surrogate light chain-dependent selection of Ig heavy chain v regions
-
Keyna U, Beck-Engeser GB, Jongstra J, Applequist SE, Jäck HM. Surrogate light chain-dependent selection of Ig heavy chain V regions. J Immunol 1995 155:5536 5542.
-
(1995)
J Immunol
, vol.155
, pp. 5536-5542
-
-
Keyna, U.1
Beck-Engeser, G.B.2
Jongstra, J.3
Applequist, S.E.4
Jäck, H.M.5
-
25
-
-
0032529224
-
Pre-B cell receptor-mediated selection of pre-B cells synthesizing functional mu heavy chains
-
Kline GH, et al. Pre-B cell receptor-mediated selection of pre-B cells synthesizing functional mu heavy chains. J Immunol 1998 161:1608 1618.
-
(1998)
J Immunol
, vol.161
, pp. 1608-1618
-
-
Kline, G.H.1
-
26
-
-
0023061742
-
Organization of the murine Ig-related lambda 5 gene transcribed selectively in pre-B lymphocytes
-
Kudo A, Sakaguchi N, Melchers F. Organization of the murine Ig-related lambda 5 gene transcribed selectively in pre-B lymphocytes. EMBO J 1987 6:103 107.
-
(1987)
EMBO J
, vol.6
, pp. 103-107
-
-
Kudo, A.1
Sakaguchi, N.2
Melchers, F.3
-
27
-
-
0023268632
-
Formation of disulphide-linked 22 tetramers in pre-B cells by the 18K -immunoglobulin light chain
-
Pillai S, Baltimore D. Formation of disulphide-linked 22 tetramers in pre-B cells by the 18K -immunoglobulin light chain. Nature 1987 329:172 174.
-
(1987)
Nature
, vol.329
, pp. 172-174
-
-
Pillai, S.1
Baltimore, D.2
-
28
-
-
32544435585
-
Powered by pairing: The surrogate light chain amplifies immunoglobulin heavy chain signaling and pre-selects the antibody repertoire
-
Vettermann C, Herrmann K, Jäck HM. Powered by pairing: the surrogate light chain amplifies immunoglobulin heavy chain signaling and pre-selects the antibody repertoire. Semin Immunol 2006 18:44 55.
-
(2006)
Semin Immunol
, vol.18
, pp. 44-55
-
-
Vettermann, C.1
Herrmann, K.2
Jäck, H.M.3
-
29
-
-
0027499537
-
Receptor editing: An approach by autoreactive B cells to escape tolerance
-
Gay D, Saunders T, Camper S, Weigert M. Receptor editing: an approach by autoreactive B cells to escape tolerance. J Exp Med 1993 177:999 1008.
-
(1993)
J Exp Med
, vol.177
, pp. 999-1008
-
-
Gay, D.1
Saunders, T.2
Camper, S.3
Weigert, M.4
-
30
-
-
0029164869
-
Light chain replacement: A new model for antibody gene rearrangement
-
Prak EL, Weigert M. Light chain replacement: a new model for antibody gene rearrangement. J Exp Med 1995 182:541 548.
-
(1995)
J Exp Med
, vol.182
, pp. 541-548
-
-
Prak, E.L.1
Weigert, M.2
-
31
-
-
0027532192
-
B lymphocytes may escape tolerance by revising their antigen receptors
-
Radic MZ, Erikson J, Litwin S, Weigert M. B lymphocytes may escape tolerance by revising their antigen receptors. J Exp Med 1993 177:1165 1173.
-
(1993)
J Exp Med
, vol.177
, pp. 1165-1173
-
-
Radic, M.Z.1
Erikson, J.2
Litwin, S.3
Weigert, M.4
-
32
-
-
0027478391
-
Receptor editing in self-reactive bone marrow B cells
-
Tiegs SL, Russell DM, Nemazee D. Receptor editing in self-reactive bone marrow B cells. J Exp Med 1993 177:1009 1020.
-
(1993)
J Exp Med
, vol.177
, pp. 1009-1020
-
-
Tiegs, S.L.1
Russell, D.M.2
Nemazee, D.3
-
33
-
-
17644363655
-
Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo
-
Novobrantseva T, et al. Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo. Int Immunol 2005 17:343 350.
-
(2005)
Int Immunol
, vol.17
, pp. 343-350
-
-
Novobrantseva, T.1
-
34
-
-
0030997499
-
Editing disease-associated autoantibodies
-
Chen C, Prak EL, Weigert M. Editing disease-associated autoantibodies. Immunity 1997 6:97 105.
-
(1997)
Immunity
, vol.6
, pp. 97-105
-
-
Chen, C.1
Prak, E.L.2
Weigert, M.3
-
35
-
-
0031424315
-
Receptor editing in a transgenic mouse model: Site, efficiency, and role in B cell tolerance and antibody diversification
-
Pelanda R, Schwers S, Sonoda E, Torres RM, Nemazee D, Rajewsky K. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity 1997 7:765 775.
-
(1997)
Immunity
, vol.7
, pp. 765-775
-
-
Pelanda, R.1
Schwers, S.2
Sonoda, E.3
Torres, R.M.4
Nemazee, D.5
Rajewsky, K.6
-
36
-
-
0022375583
-
Double recombination of a single immunoglobulin kappa-chain allele: Implications for the mechanism of rearrangement
-
Feddersen RM, Van Ness BG. Double recombination of a single immunoglobulin kappa-chain allele: implications for the mechanism of rearrangement. Proc Natl Acad Sci USA 1985 82:4793 4797.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 4793-4797
-
-
Feddersen, R.M.1
Van Ness, B.G.2
-
37
-
-
0023578923
-
How immunoglobulin v kappa genes rearrange
-
Shapiro MA, Weigert M. How immunoglobulin V kappa genes rearrange. J Immunol 1987 139:3834 3839.
-
(1987)
J Immunol
, vol.139
, pp. 3834-3839
-
-
Shapiro, M.A.1
Weigert, M.2
-
38
-
-
0342711256
-
In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
-
Lam KP, Kuhn R, Rajewsky K. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 1997 90:1073 1083.
-
(1997)
Cell
, vol.90
, pp. 1073-1083
-
-
Lam, K.P.1
Kuhn, R.2
Rajewsky, K.3
-
39
-
-
26044467886
-
Antibodies, immunoglobulin genes and the bursa of Fabricius in chicken B cell development
-
Ratcliffe MJ. Antibodies, immunoglobulin genes and the bursa of Fabricius in chicken B cell development. Dev Comp Immunol 2006 30:101 118.
-
(2006)
Dev Comp Immunol
, vol.30
, pp. 101-118
-
-
Ratcliffe, M.J.1
-
40
-
-
70349570161
-
V(D)J recombination: Of mice and sharks
-
Hsu E. V(D)J recombination: of mice and sharks. Adv Exp Med Biol 2009 650:166 179.
-
(2009)
Adv Exp Med Biol
, vol.650
, pp. 166-179
-
-
Hsu, E.1
-
41
-
-
3142598845
-
Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes to the allelic exclusion of light-chain expression
-
Liang HE, Hsu LY, Cado D, Schlissel MS. Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes to the allelic exclusion of light-chain expression. Cell 2004 118:19 29.
-
(2004)
Cell
, vol.118
, pp. 19-29
-
-
Liang, H.E.1
Hsu, L.Y.2
Cado, D.3
Schlissel, M.S.4
-
42
-
-
45549086756
-
Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments
-
Schlimgen RJ, Reddy KL, Singh H, Krangel MS. Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. Nat Immunol 2008 9:802 809.
-
(2008)
Nat Immunol
, vol.9
, pp. 802-809
-
-
Schlimgen, R.J.1
Reddy, K.L.2
Singh, H.3
Krangel, M.S.4
-
43
-
-
0019151843
-
Transcription of mouse kappa chain genes: Implications for allelic exclusion
-
Perry RP, et al. Transcription of mouse kappa chain genes: implications for allelic exclusion. Proc Natl Acad Sci USA 1980 77:1937 1941.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1937-1941
-
-
Perry, R.P.1
-
44
-
-
0035829551
-
Asynchronous replication and allelic exclusion in the immune system
-
Mostoslavsky R, et al. Asynchronous replication and allelic exclusion in the immune system. Nature 2001 414:221 225.
-
(2001)
Nature
, vol.414
, pp. 221-225
-
-
Mostoslavsky, R.1
-
45
-
-
0025439518
-
The protection: The unit of humoral immunity selected by evolution
-
Cohn M, Langman RE. The protection: the unit of humoral immunity selected by evolution. Immunol Rev 1990 115:11 147.
-
(1990)
Immunol Rev
, vol.115
, pp. 11-147
-
-
Cohn, M.1
Langman, R.E.2
-
46
-
-
0019494043
-
Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression
-
Coleclough C, Perry RP, Karjalainen K, Weigert M. Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression. Nature 1981 290:372 378.
-
(1981)
Nature
, vol.290
, pp. 372-378
-
-
Coleclough, C.1
Perry, R.P.2
Karjalainen, K.3
Weigert, M.4
-
47
-
-
0026698261
-
Allelic exclusion model questioned
-
Wabl M, Steinberg C. Allelic exclusion model questioned. Nature 1992 359:370 371.
-
(1992)
Nature
, vol.359
, pp. 370-371
-
-
Wabl, M.1
Steinberg, C.2
-
48
-
-
0020471790
-
Multiple immunoglobulin heavy-chain gene transcripts in Abelson murine leukemia virus-transformed lymphoid cell lines
-
Alt FW, Rosenberg N, Enea V, Siden E, Baltimore D. Multiple immunoglobulin heavy-chain gene transcripts in Abelson murine leukemia virus-transformed lymphoid cell lines. Mol Cell Biol 1982 2:386 400.
-
(1982)
Mol Cell Biol
, vol.2
, pp. 386-400
-
-
Alt, F.W.1
Rosenberg, N.2
Enea, V.3
Siden, E.4
Baltimore, D.5
-
49
-
-
0018929067
-
Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain
-
Alt FW, Enea V, Bothwell AL, Baltimore D. Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain. Cell 1980 21:1 12.
-
(1980)
Cell
, vol.21
, pp. 1-12
-
-
Alt, F.W.1
Enea, V.2
Bothwell, A.L.3
Baltimore, D.4
-
50
-
-
0033198563
-
Frequencies of multiple IgL chain gene rearrangements in single normal or kappaL chain-deficient B lineage cells
-
Yamagami T, ten Boekel E, Andersson J, Rolink A, Melchers F. Frequencies of multiple IgL chain gene rearrangements in single normal or kappaL chain-deficient B lineage cells. Immunity 1999 11:317 327.
-
(1999)
Immunity
, vol.11
, pp. 317-327
-
-
Yamagami, T.1
Ten Boekel, E.2
Andersson, J.3
Rolink, A.4
Melchers, F.5
-
51
-
-
67349228524
-
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci
-
Hewitt SL, et al. RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol 2009 10:655 664.
-
(2009)
Nat Immunol
, vol.10
, pp. 655-664
-
-
Hewitt, S.L.1
-
53
-
-
0023123376
-
Allelic inclusion in a pre-B-cell line that generates immunoglobulin heavy chain genes in vitro
-
Beck-Engeser G, Jäck HM, Wabl M. Allelic inclusion in a pre-B-cell line that generates immunoglobulin heavy chain genes in vitro. Proc Natl Acad Sci USA 1987 84:1060 1064.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 1060-1064
-
-
Beck-Engeser, G.1
Jäck, H.M.2
Wabl, M.3
-
54
-
-
0019188771
-
Immunoglobulin chain loss in hybridoma lines
-
Kohler G. Immunoglobulin chain loss in hybridoma lines. Proc Natl Acad Sci USA 1980 77:2197 2199.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 2197-2199
-
-
Kohler, G.1
-
55
-
-
0026583842
-
Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion
-
Kitamura D, Rajewsky K. Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion. Nature 1992 356:154 156.
-
(1992)
Nature
, vol.356
, pp. 154-156
-
-
Kitamura, D.1
Rajewsky, K.2
-
56
-
-
0029886467
-
Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development
-
Loffert D, Ehlich A, Muller W, Rajewsky K. Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development. Immunity 1996 4:133 144.
-
(1996)
Immunity
, vol.4
, pp. 133-144
-
-
Loffert, D.1
Ehlich, A.2
Muller, W.3
Rajewsky, K.4
-
57
-
-
46749088320
-
The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis
-
Neubert K, et al. The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis. Nat Med 2008 14:748 755.
-
(2008)
Nat Med
, vol.14
, pp. 748-755
-
-
Neubert, K.1
-
58
-
-
60549108600
-
A role for the IgH intronic enhancer e mu in enforcing allelic exclusion
-
Li F, Eckhardt LA. A role for the IgH intronic enhancer E mu in enforcing allelic exclusion. J Exp Med 2009 206:153 167.
-
(2009)
J Exp Med
, vol.206
, pp. 153-167
-
-
Li, F.1
Eckhardt, L.A.2
-
59
-
-
0037023361
-
Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
-
Kosak ST, et al. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 2002 296:158 162.
-
(2002)
Science
, vol.296
, pp. 158-162
-
-
Kosak, S.T.1
-
60
-
-
13944262010
-
Epigenetic ontogeny of the Igk locus during B cell development
-
Goldmit M, et al. Epigenetic ontogeny of the Igk locus during B cell development. Nat Immunol 2005 6:198 203.
-
(2005)
Nat Immunol
, vol.6
, pp. 198-203
-
-
Goldmit, M.1
-
61
-
-
0035879185
-
Chromatin remodeling at the Ig loci prior to V(D)J recombination
-
Maes J, O'Neill LP, Cavelier P, Turner BM, Rougeon F, Goodhardt M. Chromatin remodeling at the Ig loci prior to V(D)J recombination. J Immunol 2001 167:866 874.
-
(2001)
J Immunol
, vol.167
, pp. 866-874
-
-
Maes, J.1
O'Neill, L.P.2
Cavelier, P.3
Turner, B.M.4
Rougeon, F.5
Goodhardt, M.6
-
62
-
-
38449089992
-
Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus
-
Fitzsimmons SP, Bernstein RM, Max EE, Skok JA, Shapiro MA. Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus. J Immunol 2007 179:5264 5273.
-
(2007)
J Immunol
, vol.179
, pp. 5264-5273
-
-
Fitzsimmons, S.P.1
Bernstein, R.M.2
Max, E.E.3
Skok, J.A.4
Shapiro, M.A.5
-
63
-
-
0141705373
-
Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4
-
Morshead KB, Ciccone DN, Taverna SD, Allis CD, Oettinger MA. Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc Natl Acad Sci USA 2003 100:11577 11582.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11577-11582
-
-
Morshead, K.B.1
Ciccone, D.N.2
Taverna, S.D.3
Allis, C.D.4
Oettinger, M.A.5
-
64
-
-
0035282573
-
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
-
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 2001 410:116 120.
-
(2001)
Nature
, vol.410
, pp. 116-120
-
-
Lachner, M.1
O'Carroll, D.2
Rea, S.3
Mechtler, K.4
Jenuwein, T.5
-
65
-
-
0035815360
-
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
-
Nakayama J, Rice JC, Strahl BD, Allis CD, Grewal SI. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 2001 292:110 113.
-
(2001)
Science
, vol.292
, pp. 110-113
-
-
Nakayama, J.1
Rice, J.C.2
Strahl, B.D.3
Allis, C.D.4
Grewal, S.I.5
-
66
-
-
0347539781
-
Histone H2AH2B dimer exchange by ATP-dependent chromatin remodeling activities
-
Bruno M, Flaus A, Stockdale C, Rencurel C, Ferreira H, Owen-Hughes T. Histone H2AH2B dimer exchange by ATP-dependent chromatin remodeling activities. Mol Cell 2003 12:1599 1606.
-
(2003)
Mol Cell
, vol.12
, pp. 1599-1606
-
-
Bruno, M.1
Flaus, A.2
Stockdale, C.3
Rencurel, C.4
Ferreira, H.5
Owen-Hughes, T.6
-
67
-
-
0037292355
-
SWISNF unwraps, slides, and rewraps the nucleosome
-
Kassabov SR, Zhang B, Persinger J, Bartholomew B. SWISNF unwraps, slides, and rewraps the nucleosome. Mol Cell 2003 11:391 403.
-
(2003)
Mol Cell
, vol.11
, pp. 391-403
-
-
Kassabov, S.R.1
Zhang, B.2
Persinger, J.3
Bartholomew, B.4
-
68
-
-
0033524939
-
Histone octamer transfer by a chromatin-remodeling complex
-
Lorch Y, Zhang M, Kornberg RD. Histone octamer transfer by a chromatin-remodeling complex. Cell 1999 96:389 392.
-
(1999)
Cell
, vol.96
, pp. 389-392
-
-
Lorch, Y.1
Zhang, M.2
Kornberg, R.D.3
-
70
-
-
0033584369
-
Nucleosome mobilization catalysed by the yeast SWISNF complex
-
Whitehouse I, Flaus A, Cairns BR, White MF, Workman JL, Owen-Hughes T. Nucleosome mobilization catalysed by the yeast SWISNF complex. Nature 1999 400:784 787.
-
(1999)
Nature
, vol.400
, pp. 784-787
-
-
Whitehouse, I.1
Flaus, A.2
Cairns, B.R.3
White, M.F.4
Workman, J.L.5
Owen-Hughes, T.6
-
71
-
-
0034704815
-
The Gcn5 bromodomain co-ordinates nucleosome remodelling
-
Syntichaki P, Topalidou I, Thireos G. The Gcn5 bromodomain co-ordinates nucleosome remodelling. Nature 2000 404:414 417.
-
(2000)
Nature
, vol.404
, pp. 414-417
-
-
Syntichaki, P.1
Topalidou, I.2
Thireos, G.3
-
72
-
-
0036847620
-
Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes
-
Hassan AH, et al. Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes. Cell 2002 111:369 379.
-
(2002)
Cell
, vol.111
, pp. 369-379
-
-
Hassan, A.H.1
-
73
-
-
0034175813
-
Stimulation of V(D)J recombination by histone acetylation
-
McBlane F, Boyes J. Stimulation of V(D)J recombination by histone acetylation. Curr Biol 2000 10:483 486.
-
(2000)
Curr Biol
, vol.10
, pp. 483-486
-
-
McBlane, F.1
Boyes, J.2
-
74
-
-
0033168204
-
Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase
-
Golding A, Chandler S, Ballestar E, Wolffe AP, Schlissel MS. Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase. EMBO J 1999 18:3712 3723.
-
(1999)
EMBO J
, vol.18
, pp. 3712-3723
-
-
Golding, A.1
Chandler, S.2
Ballestar, E.3
Wolffe, A.P.4
Schlissel, M.S.5
-
75
-
-
0032239155
-
Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1
-
Kwon J, Imbalzano AN, Matthews A, Oettinger MA. Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1. Mol Cell 1998 2:829 839.
-
(1998)
Mol Cell
, vol.2
, pp. 829-839
-
-
Kwon, J.1
Imbalzano, A.N.2
Matthews, A.3
Oettinger, M.A.4
-
76
-
-
0033638506
-
Histone acetylation and hSWISNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA
-
Kwon J, Morshead KB, Guyon JR, Kingston RE, Oettinger MA. Histone acetylation and hSWISNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol Cell 2000 6:1037 1048.
-
(2000)
Mol Cell
, vol.6
, pp. 1037-1048
-
-
Kwon, J.1
Morshead, K.B.2
Guyon, J.R.3
Kingston, R.E.4
Oettinger, M.A.5
-
77
-
-
50249154114
-
Activation of 1223-RSS-dependent RAG cleavage by hSWISNF complex in the absence of transcription
-
Du H, Ishii H, Pazin MJ, Sen R. Activation of 1223-RSS-dependent RAG cleavage by hSWISNF complex in the absence of transcription. Mol Cell 2008 31:641 649.
-
(2008)
Mol Cell
, vol.31
, pp. 641-649
-
-
Du, H.1
Ishii, H.2
Pazin, M.J.3
Sen, R.4
-
78
-
-
4143089242
-
ATP-dependent remodeling by SWISNF and ISWI proteins stimulates V(D)J cleavage of 5 S arrays
-
Patenge N, Elkin SK, Oettinger MA. ATP-dependent remodeling by SWISNF and ISWI proteins stimulates V(D)J cleavage of 5 S arrays. J Biol Chem 2004 279:35360 35367.
-
(2004)
J Biol Chem
, vol.279
, pp. 35360-35367
-
-
Patenge, N.1
Elkin, S.K.2
Oettinger, M.A.3
-
79
-
-
33745839365
-
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
-
Wysocka J, et al. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 2006 442:86 90.
-
(2006)
Nature
, vol.442
, pp. 86-90
-
-
Wysocka, J.1
-
80
-
-
0037229028
-
Pax5 is required for recombination of transcribed, acetylated, 5′ IgH v gene segments
-
Hesslein DG, Pflugh DL, Chowdhury D, Bothwell AL, Sen R, Schatz DG. Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments. Genes Dev 2003 17:37 42.
-
(2003)
Genes Dev
, vol.17
, pp. 37-42
-
-
Hesslein, D.G.1
Pflugh, D.L.2
Chowdhury, D.3
Bothwell, A.L.4
Sen, R.5
Schatz, D.G.6
-
81
-
-
0037125979
-
Regulation of V(D)J recombination: A dominant role for promoter positioning in gene segment accessibility
-
Sikes ML, Meade A, Tripathi R, Krangel MS, Oltz EM. Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility. Proc Natl Acad Sci USA 2002 99:12309 12314.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12309-12314
-
-
Sikes, M.L.1
Meade, A.2
Tripathi, R.3
Krangel, M.S.4
Oltz, E.M.5
-
82
-
-
70350462285
-
Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci
-
Beck K, Peak MM, Ota T, Nemazee D, Murre C. Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci. J Exp Med 2009 206:2271 2284.
-
(2009)
J Exp Med
, vol.206
, pp. 2271-2284
-
-
Beck, K.1
Peak, M.M.2
Ota, T.3
Nemazee, D.4
Murre, C.5
-
83
-
-
0037232230
-
A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines
-
Muljo SA, Schlissel MS. A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines. Nat Immunol 2003 4:31 37.
-
(2003)
Nat Immunol
, vol.4
, pp. 31-37
-
-
Muljo, S.A.1
Schlissel, M.S.2
-
84
-
-
34548262714
-
Transcriptome analysis in primary B lymphoid precursors following induction of the pre-B cell receptor
-
Schuh W, Meister S, Herrmann K, Bradl H, Jack HM. Transcriptome analysis in primary B lymphoid precursors following induction of the pre-B cell receptor. Mol Immunol 2008 45:362 375.
-
(2008)
Mol Immunol
, vol.45
, pp. 362-375
-
-
Schuh, W.1
Meister, S.2
Herrmann, K.3
Bradl, H.4
Jack, H.M.5
-
85
-
-
0024435908
-
Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription
-
Schlissel MS, Baltimore D. Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription. Cell 1989 58:1001 1007.
-
(1989)
Cell
, vol.58
, pp. 1001-1007
-
-
Schlissel, M.S.1
Baltimore, D.2
-
86
-
-
34848911602
-
Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4
-
Vermeulen M, et al. Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4. Cell 2007 131:58 69.
-
(2007)
Cell
, vol.131
, pp. 58-69
-
-
Vermeulen, M.1
-
87
-
-
0036097492
-
Essential roles of the kappa light chain intronic enhancer and 3′ enhancer in kappa rearrangement and demethylation
-
Inlay M, Alt FW, Baltimore D, Xu Y. Essential roles of the kappa light chain intronic enhancer and 3′ enhancer in kappa rearrangement and demethylation. Nat Immunol 2002 3:463 468.
-
(2002)
Nat Immunol
, vol.3
, pp. 463-468
-
-
Inlay, M.1
Alt, F.W.2
Baltimore, D.3
Xu, Y.4
-
88
-
-
0033519234
-
A targeted deletion of a region upstream from the Jkappa cluster impairs kappa chain rearrangement in cis in mice and in the 103bcl2 cell line
-
Cocea L, et al. A targeted deletion of a region upstream from the Jkappa cluster impairs kappa chain rearrangement in cis in mice and in the 103bcl2 cell line. J Exp Med 1999 189:1443 1450.
-
(1999)
J Exp Med
, vol.189
, pp. 1443-1450
-
-
Cocea, L.1
-
89
-
-
0029983577
-
Rearrangement-enhancing element upstream of the mouse immunoglobulin kappa chain J cluster
-
Ferradini L, Gu H, De Smet A, Rajewsky K, Reynaud CA, Weill JC. Rearrangement-enhancing element upstream of the mouse immunoglobulin kappa chain J cluster. Science 1996 271:1416 1420.
-
(1996)
Science
, vol.271
, pp. 1416-1420
-
-
Ferradini, L.1
Gu, H.2
De Smet, A.3
Rajewsky, K.4
Reynaud, C.A.5
Weill, J.C.6
-
90
-
-
0029030481
-
The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate
-
Fernex C, Capone M, Ferrier P. The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate. Mol Cell Biol 1995 15:3217 3226.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3217-3226
-
-
Fernex, C.1
Capone, M.2
Ferrier, P.3
-
91
-
-
33748850103
-
Regulation of T cell receptor-alpha gene recombination by transcription
-
Abarrategui I, Krangel MS. Regulation of T cell receptor-alpha gene recombination by transcription. Nat Immunol 2006 7:1109 1115.
-
(2006)
Nat Immunol
, vol.7
, pp. 1109-1115
-
-
Abarrategui, I.1
Krangel, M.S.2
-
92
-
-
0033166761
-
A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme
-
Wittschieben BO, et al. A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme. Mol Cell 1999 4:123 128.
-
(1999)
Mol Cell
, vol.4
, pp. 123-128
-
-
Wittschieben, B.O.1
-
93
-
-
0037524702
-
The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: Linking transcriptional elongation to histone methylation
-
Krogan NJ, et al. The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 2003 11:721 729.
-
(2003)
Mol Cell
, vol.11
, pp. 721-729
-
-
Krogan, N.J.1
-
94
-
-
0344022572
-
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity
-
Ng HH, Robert F, Young RA, Struhl K. Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity. Mol Cell 2003 11:709 719.
-
(2003)
Mol Cell
, vol.11
, pp. 709-719
-
-
Ng, H.H.1
Robert, F.2
Young, R.A.3
Struhl, K.4
-
95
-
-
0041828954
-
FACT facilitates transcription-dependent nucleosome alteration
-
Belotserkovskaya R, Oh S, Bondarenko VA, Orphanides G, Studitsky VM, Reinberg D. FACT facilitates transcription-dependent nucleosome alteration. Science 2003 301:1090 1093.
-
(2003)
Science
, vol.301
, pp. 1090-1093
-
-
Belotserkovskaya, R.1
Oh, S.2
Bondarenko, V.A.3
Orphanides, G.4
Studitsky, V.M.5
Reinberg, D.6
-
96
-
-
33646141366
-
Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II
-
Schwabish MA, Struhl K. Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II. Mol Cell 2006 22:415 422.
-
(2006)
Mol Cell
, vol.22
, pp. 415-422
-
-
Schwabish, M.A.1
Struhl, K.2
-
97
-
-
9144274420
-
Evidence for distinct mechanisms facilitating transcript elongation through chromatin in vivo
-
Kristjuhan A, Svejstrup JQ. Evidence for distinct mechanisms facilitating transcript elongation through chromatin in vivo. EMBO J 2004 23:4243 4252.
-
(2004)
EMBO J
, vol.23
, pp. 4243-4252
-
-
Kristjuhan, A.1
Svejstrup, J.Q.2
-
98
-
-
58849152743
-
Biallelic, ubiquitous transcription from the distal germline Ig locus promoter during B cell development
-
Amin RH, et al. Biallelic, ubiquitous transcription from the distal germline Ig locus promoter during B cell development. Proc Natl Acad Sci USA 2009 106:522 527.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 522-527
-
-
Amin, R.H.1
-
99
-
-
58849149380
-
A reappraisal of evidence for probabilistic models of allelic exclusion
-
Taylor B, Cobb BS, Bruno L, Webster Z, Fisher AG, Merkenschlager M. A reappraisal of evidence for probabilistic models of allelic exclusion. Proc Natl Acad Sci USA 2009 106:516 521.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 516-521
-
-
Taylor, B.1
Cobb, B.S.2
Bruno, L.3
Webster, Z.4
Fisher, A.G.5
Merkenschlager, M.6
-
100
-
-
0345268756
-
Biallelic germline transcription at the kappa immunoglobulin locus
-
Singh N, Bergman Y, Cedar H, Chess A. Biallelic germline transcription at the kappa immunoglobulin locus. J Exp Med 2003 197:743 750.
-
(2003)
J Exp Med
, vol.197
, pp. 743-750
-
-
Singh, N.1
Bergman, Y.2
Cedar, H.3
Chess, A.4
-
101
-
-
34948910234
-
Transcription of productive and nonproductive VDJ-recombined alleles after IgH allelic exclusion
-
Daly J, Licence S, Nanou A, Morgan G, Martensson IL. Transcription of productive and nonproductive VDJ-recombined alleles after IgH allelic exclusion. EMBO J 2007 26:4273 4282.
-
(2007)
EMBO J
, vol.26
, pp. 4273-4282
-
-
Daly, J.1
Licence, S.2
Nanou, A.3
Morgan, G.4
Martensson, I.L.5
-
102
-
-
2942691957
-
Antisense intergenic transcription in V(D)J recombination
-
Bolland DJ, et al. Antisense intergenic transcription in V(D)J recombination. Nat Immunol 2004 5:630 637.
-
(2004)
Nat Immunol
, vol.5
, pp. 630-637
-
-
Bolland, D.J.1
-
103
-
-
37249041657
-
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination
-
Matthews AG, et al. RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature 2007 450:1106 1110.
-
(2007)
Nature
, vol.450
, pp. 1106-1110
-
-
Matthews, A.G.1
-
104
-
-
23844471918
-
A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination
-
West KL, et al. A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination. Immunity 2005 23:203 212.
-
(2005)
Immunity
, vol.23
, pp. 203-212
-
-
West, K.L.1
-
105
-
-
35349024178
-
A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement
-
Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S. A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity 2007 27:561 571.
-
(2007)
Immunity
, vol.27
, pp. 561-571
-
-
Liu, Y.1
Subrahmanyam, R.2
Chakraborty, T.3
Sen, R.4
Desiderio, S.5
-
106
-
-
66749124789
-
H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: Implications for translocations
-
Shimazaki N, Tsai AG, Lieber MR. H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations. Mol Cell 2009 34:535 544.
-
(2009)
Mol Cell
, vol.34
, pp. 535-544
-
-
Shimazaki, N.1
Tsai, A.G.2
Lieber, M.R.3
-
107
-
-
0036850786
-
The 'dispensable' portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development
-
Liang HE, Hsu LY, Cado D, Cowell LG, Kelsoe G, Schlissel MS. The 'dispensable' portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development. Immunity 2002 17:639 651.
-
(2002)
Immunity
, vol.17
, pp. 639-651
-
-
Liang, H.E.1
Hsu, L.Y.2
Cado, D.3
Cowell, L.G.4
Kelsoe, G.5
Schlissel, M.S.6
-
108
-
-
0037417795
-
Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice
-
Akamatsu Y, et al. Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice. Proc Natl Acad Sci USA 2003 100:1209 1214.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1209-1214
-
-
Akamatsu, Y.1
-
109
-
-
33847334699
-
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
-
Heintzman ND, et al. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet 2007 39:311 318.
-
(2007)
Nat Genet
, vol.39
, pp. 311-318
-
-
Heintzman, N.D.1
-
110
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells
-
Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 2007 130:77 88.
-
(2007)
Cell
, vol.130
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
111
-
-
37649026007
-
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2
-
Ramon-Maiques S, et al. The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc Natl Acad Sci USA 2007 104:18993 18998.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 18993-18998
-
-
Ramon-Maiques, S.1
-
112
-
-
12344270023
-
Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene
-
Roldan E, et al. Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene. Nat Immunol 2005 6:31 41.
-
(2005)
Nat Immunol
, vol.6
, pp. 31-41
-
-
Roldan, E.1
-
113
-
-
33645983936
-
A recombination silencer that specifies heterochromatin positioning and ikaros association in the immunoglobulin kappa locus
-
Liu Z, et al. A recombination silencer that specifies heterochromatin positioning and ikaros association in the immunoglobulin kappa locus. Immunity 2006 24:405 415.
-
(2006)
Immunity
, vol.24
, pp. 405-415
-
-
Liu, Z.1
-
114
-
-
0037031831
-
Chromatin structural analyses of the mouse Igkappa gene locus reveal new hypersensitive sites specifying a transcriptional silencer and enhancer
-
Liu ZM, George-Raizen JB, Li S, Meyers KC, Chang MY, Garrard WT. Chromatin structural analyses of the mouse Igkappa gene locus reveal new hypersensitive sites specifying a transcriptional silencer and enhancer. J Biol Chem 2002 277:32640 32649.
-
(2002)
J Biol Chem
, vol.277
, pp. 32640-32649
-
-
Liu, Z.M.1
George-Raizen, J.B.2
Li, S.3
Meyers, K.C.4
Chang, M.Y.5
Garrard, W.T.6
-
115
-
-
59849122478
-
Cutting edge: Developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development
-
Degner SC, Wong TP, Jankevicius G, Feeney AJ. Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. J Immunol 2009 182:44 48.
-
(2009)
J Immunol
, vol.182
, pp. 44-48
-
-
Degner, S.C.1
Wong, T.P.2
Jankevicius, G.3
Feeney, A.J.4
-
116
-
-
0035554683
-
Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes
-
Skok JA, et al. Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes. Nat Immunol 2001 2:848 854.
-
(2001)
Nat Immunol
, vol.2
, pp. 848-854
-
-
Skok, J.A.1
-
117
-
-
0038387866
-
Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication
-
Azuara V, et al. Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication. Nat Cell Biol 2003 5:668 674.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 668-674
-
-
Azuara, V.1
-
119
-
-
0036792721
-
Differential accessibility at the kappa chain locus plays a role in allelic exclusion
-
Goldmit M, Schlissel M, Cedar H, Bergman Y. Differential accessibility at the kappa chain locus plays a role in allelic exclusion. EMBO J 2002 21:5255 5261.
-
(2002)
EMBO J
, vol.21
, pp. 5255-5261
-
-
Goldmit, M.1
Schlissel, M.2
Cedar, H.3
Bergman, Y.4
-
120
-
-
0025828597
-
A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci
-
Engler P, et al. A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci. Cell 1991 65:939 947.
-
(1991)
Cell
, vol.65
, pp. 939-947
-
-
Engler, P.1
-
121
-
-
0026507505
-
CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication
-
Hsieh CL, Lieber MR. CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication. EMBO J 1992 11:315 325.
-
(1992)
EMBO J
, vol.11
, pp. 315-325
-
-
Hsieh, C.L.1
Lieber, M.R.2
-
122
-
-
0041852607
-
Effect of CpG methylation on RAG1RAG2 reactivity: Implications of direct and indirect mechanisms for controlling V(D)J cleavage
-
Nakase H, Takahama Y, Akamatsu Y. Effect of CpG methylation on RAG1RAG2 reactivity: implications of direct and indirect mechanisms for controlling V(D)J cleavage. EMBO Rep 2003 4:774 780.
-
(2003)
EMBO Rep
, vol.4
, pp. 774-780
-
-
Nakase, H.1
Takahama, Y.2
Akamatsu, Y.3
-
123
-
-
0033601073
-
Methylation-induced repression - Belts, braces, and chromatin
-
Bird AP, Wolffe AP. Methylation-induced repression - belts, braces, and chromatin. Cell 1999 99:451 454.
-
(1999)
Cell
, vol.99
, pp. 451-454
-
-
Bird, A.P.1
Wolffe, A.P.2
-
124
-
-
0030038608
-
A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus
-
Kirillov A, Kistler B, Mostoslavsky R, Cedar H, Wirth T, Bergman Y. A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus. Nat Genet 1996 13:435 441.
-
(1996)
Nat Genet
, vol.13
, pp. 435-441
-
-
Kirillov, A.1
Kistler, B.2
Mostoslavsky, R.3
Cedar, H.4
Wirth, T.5
Bergman, Y.6
-
125
-
-
0032526136
-
Kappa chain monoallelic demethylation and the establishment of allelic exclusion
-
Mostoslavsky R, et al. Kappa chain monoallelic demethylation and the establishment of allelic exclusion. Genes Dev 1998 12:1801 1811.
-
(1998)
Genes Dev
, vol.12
, pp. 1801-1811
-
-
Mostoslavsky, R.1
-
126
-
-
67349211157
-
Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals
-
Derudder E, et al. Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals. Nat Immunol 2009 10:647 654.
-
(2009)
Nat Immunol
, vol.10
, pp. 647-654
-
-
Derudder, E.1
-
127
-
-
33750836920
-
VH replacement rescues progenitor B cells with two nonproductive VDJ alleles
-
Lutz J, Muller W, Jack HM. VH replacement rescues progenitor B cells with two nonproductive VDJ alleles. J Immunol 2006 177:7007 7014.
-
(2006)
J Immunol
, vol.177
, pp. 7007-7014
-
-
Lutz, J.1
Muller, W.2
Jack, H.M.3
-
128
-
-
33746004544
-
Antibody repertoires generated by VH replacement and direct VH to JH joining
-
Koralov SB, Novobrantseva TI, Konigsmann J, Ehlich A, Rajewsky K. Antibody repertoires generated by VH replacement and direct VH to JH joining. Immunity 2006 25:43 53.
-
(2006)
Immunity
, vol.25
, pp. 43-53
-
-
Koralov, S.B.1
Novobrantseva, T.I.2
Konigsmann, J.3
Ehlich, A.4
Rajewsky, K.5
-
129
-
-
0022502863
-
Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma
-
Kleinfield R, Hardy RR, Tarlinton D, Dangl J, Herzenberg LA, Weigert M. Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma. Nature 1986 322:843 846.
-
(1986)
Nature
, vol.322
, pp. 843-846
-
-
Kleinfield, R.1
Hardy, R.R.2
Tarlinton, D.3
Dangl, J.4
Herzenberg, L.A.5
Weigert, M.6
-
130
-
-
0022557584
-
A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production
-
Reth M, Gehrmann P, Petrac E, Wiese P. A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production. Nature 1986 322:840 842.
-
(1986)
Nature
, vol.322
, pp. 840-842
-
-
Reth, M.1
Gehrmann, P.2
Petrac, E.3
Wiese, P.4
-
131
-
-
0023189116
-
Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu
-
Nussenzweig MC, et al. Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu. Science 1987 236:816 819.
-
(1987)
Science
, vol.236
, pp. 816-819
-
-
Nussenzweig, M.C.1
-
132
-
-
0022385230
-
A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes
-
Weaver D, Costantini F, Imanishi-Kari T, Baltimore D. A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes. Cell 1985 42:117 127.
-
(1985)
Cell
, vol.42
, pp. 117-127
-
-
Weaver, D.1
Costantini, F.2
Imanishi-Kari, T.3
Baltimore, D.4
-
133
-
-
0023685531
-
Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains
-
Manz J, Denis K, Witte O, Brinster R, Storb U. Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains. J Exp Med 1988 168:1363 1381.
-
(1988)
J Exp Med
, vol.168
, pp. 1363-1381
-
-
Manz, J.1
Denis, K.2
Witte, O.3
Brinster, R.4
Storb, U.5
-
134
-
-
0021680505
-
Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice
-
Ritchie KA, Brinster RL, Storb U. Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice. Nature 1984 312:517 520.
-
(1984)
Nature
, vol.312
, pp. 517-520
-
-
Ritchie, K.A.1
Brinster, R.L.2
Storb, U.3
-
135
-
-
0023513562
-
Expression of immunoglobulin delta chain causes allelic exclusion in transgenic mice
-
Iglesias A, Lamers M, Kohler G. Expression of immunoglobulin delta chain causes allelic exclusion in transgenic mice. Nature 1987 330:482 484.
-
(1987)
Nature
, vol.330
, pp. 482-484
-
-
Iglesias, A.1
Lamers, M.2
Kohler, G.3
-
136
-
-
0030249394
-
A prematurely expressed Ig(kappa) transgene, but not V(kappa)J(kappa) gene segment targeted into the Ig(kappa) locus, can rescue B cell development in lambda5-deficient mice
-
Pelanda R, Schaal S, Torres RM, Rajewsky K. A prematurely expressed Ig(kappa) transgene, but not V(kappa)J(kappa) gene segment targeted into the Ig(kappa) locus, can rescue B cell development in lambda5-deficient mice. Immunity 1996 5:229 239.
-
(1996)
Immunity
, vol.5
, pp. 229-239
-
-
Pelanda, R.1
Schaal, S.2
Torres, R.M.3
Rajewsky, K.4
-
137
-
-
0037396717
-
Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion
-
Schweighoffer E, Vanes L, Mathiot A, Nakamura T, Tybulewicz VL. Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion. Immunity 2003 18:523 533.
-
(2003)
Immunity
, vol.18
, pp. 523-533
-
-
Schweighoffer, E.1
Vanes, L.2
Mathiot, A.3
Nakamura, T.4
Tybulewicz, V.L.5
-
138
-
-
3843100621
-
The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells
-
Meade J, Tybulewicz VL, Turner M. The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells. Eur J Immunol 2004 34:1102 1110.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1102-1110
-
-
Meade, J.1
Tybulewicz, V.L.2
Turner, M.3
-
139
-
-
0028828269
-
Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement
-
Grawunder U, et al. Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement. Immunity 1995 3:601 608.
-
(1995)
Immunity
, vol.3
, pp. 601-608
-
-
Grawunder, U.1
-
140
-
-
0027275497
-
The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver
-
Li YS, Hayakawa K, Hardy RR. The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. J Exp Med 1993 178:951 960.
-
(1993)
J Exp Med
, vol.178
, pp. 951-960
-
-
Li, Y.S.1
Hayakawa, K.2
Hardy, R.R.3
-
141
-
-
2942642372
-
Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components
-
Galler GR, Mundt C, Parker M, Pelanda R, Martensson IL, Winkler TH. Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components. J Exp Med 2004 199:1523 1532.
-
(2004)
J Exp Med
, vol.199
, pp. 1523-1532
-
-
Galler, G.R.1
Mundt, C.2
Parker, M.3
Pelanda, R.4
Martensson, I.L.5
Winkler, T.H.6
-
142
-
-
0032958092
-
Distinct factors regulate the murine RAG-2 promoter in B- and T-cell lines
-
Lauring J, Schlissel MS. Distinct factors regulate the murine RAG-2 promoter in B- and T-cell lines. Mol Cell Biol 1999 19:2601 2612.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2601-2612
-
-
Lauring, J.1
Schlissel, M.S.2
-
143
-
-
0037079724
-
Cooperative binding of c-Myb and Pax-5 activates the RAG-2 promoter in immature B cells
-
Kishi H, et al. Cooperative binding of c-Myb and Pax-5 activates the RAG-2 promoter in immature B cells. Blood 2002 99:576 583.
-
(2002)
Blood
, vol.99
, pp. 576-583
-
-
Kishi, H.1
-
144
-
-
0036784604
-
Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells
-
Jin ZX, Kishi H, Wei XC, Matsuda T, Saito S, Muraguchi A. Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells. J Immunol 2002 169:3783 3792.
-
(2002)
J Immunol
, vol.169
, pp. 3783-3792
-
-
Jin, Z.X.1
Kishi, H.2
Wei, X.C.3
Matsuda, T.4
Saito, S.5
Muraguchi, A.6
-
145
-
-
44049091757
-
Foxo1 directly regulates the transcription of recombination-activating genes during B cell development
-
Amin RH, Schlissel MS. Foxo1 directly regulates the transcription of recombination-activating genes during B cell development. Nat Immunol 2008 9:613 622.
-
(2008)
Nat Immunol
, vol.9
, pp. 613-622
-
-
Amin, R.H.1
Schlissel, M.S.2
-
146
-
-
56349127778
-
Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation
-
Dengler HS, et al. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol 2008 9:1388 1398.
-
(2008)
Nat Immunol
, vol.9
, pp. 1388-1398
-
-
Dengler, H.S.1
-
147
-
-
0027296517
-
Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation
-
Lin WC, Desiderio S. Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation. Science 1993 260:953 959.
-
(1993)
Science
, vol.260
, pp. 953-959
-
-
Lin, W.C.1
Desiderio, S.2
-
148
-
-
0033427205
-
Cyclin ACDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair
-
Lee J, Desiderio S. Cyclin ACDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair. Immunity 1999 11:771 781.
-
(1999)
Immunity
, vol.11
, pp. 771-781
-
-
Lee, J.1
Desiderio, S.2
-
149
-
-
20444403003
-
Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle
-
Jiang H, et al. Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle. Mol Cell 2005 18:699 709.
-
(2005)
Mol Cell
, vol.18
, pp. 699-709
-
-
Jiang, H.1
-
150
-
-
0029978830
-
The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression
-
Grawunder U, Schatz DG, Leu TM, Rolink A, Melchers F. The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression. J Exp Med 1996 183:1731 1737.
-
(1996)
J Exp Med
, vol.183
, pp. 1731-1737
-
-
Grawunder, U.1
Schatz, D.G.2
Leu, T.M.3
Rolink, A.4
Melchers, F.5
-
151
-
-
0030498092
-
A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle
-
Li Z, Dordai DI, Lee J, Desiderio S. A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle. Immunity 1996 5:575 589.
-
(1996)
Immunity
, vol.5
, pp. 575-589
-
-
Li, Z.1
Dordai, D.I.2
Lee, J.3
Desiderio, S.4
-
152
-
-
0028135022
-
TCR selection and allelic exclusion in RAG transgenic mice that exhibit abnormal T cell localization in lymph nodes and lymphatics
-
Wayne J, et al. TCR selection and allelic exclusion in RAG transgenic mice that exhibit abnormal T cell localization in lymph nodes and lymphatics. J Immunol 1994 153:5491 5502.
-
(1994)
J Immunol
, vol.153
, pp. 5491-5502
-
-
Wayne, J.1
-
153
-
-
0033215223
-
The roles of preB and B cell receptors in the stepwise allelic exclusion of mouse IgH and L chain gene loci
-
Melchers F, ten Boekel E, Yamagami T, Andersson J, Rolink A. The roles of preB and B cell receptors in the stepwise allelic exclusion of mouse IgH and L chain gene loci. Semin Immunol 1999 11:307 317.
-
(1999)
Semin Immunol
, vol.11
, pp. 307-317
-
-
Melchers, F.1
Ten Boekel, E.2
Yamagami, T.3
Andersson, J.4
Rolink, A.5
-
154
-
-
0027274745
-
Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci
-
Rolink A, Grawunder U, Haasner D, Strasser A, Melchers F. Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci. J Exp Med 1993 178:1263 1270.
-
(1993)
J Exp Med
, vol.178
, pp. 1263-1270
-
-
Rolink, A.1
Grawunder, U.2
Haasner, D.3
Strasser, A.4
Melchers, F.5
-
155
-
-
0033549813
-
Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization
-
Yu W, et al. Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization. Nature 1999 400:682 687.
-
(1999)
Nature
, vol.400
, pp. 682-687
-
-
Yu, W.1
-
156
-
-
1542377316
-
Targeted inhibition of V(D)J recombination by a histone methyltransferase
-
Osipovich O, et al. Targeted inhibition of V(D)J recombination by a histone methyltransferase. Nat Immunol 2004 5:309 316.
-
(2004)
Nat Immunol
, vol.5
, pp. 309-316
-
-
Osipovich, O.1
-
157
-
-
0026534145
-
Chromosomal position of rearranging gene segments influences allelic exclusion in transgenic mice
-
Costa TE, Suh H, Nussenzweig MC. Chromosomal position of rearranging gene segments influences allelic exclusion in transgenic mice. Proc Natl Acad Sci USA 1992 89:2205 2208.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2205-2208
-
-
Costa, T.E.1
Suh, H.2
Nussenzweig, M.C.3
-
158
-
-
77949811269
-
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci
-
Hewitt SL, et al. RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol 2010 11:355 356.
-
(2010)
Nat Immunol
, vol.11
, pp. 355-356
-
-
Hewitt, S.L.1
-
159
-
-
33750091312
-
Generation of heavy-chain-only antibodies in mice
-
Janssens R, et al. Generation of heavy-chain-only antibodies in mice. Proc Natl Acad Sci USA 2006 103:15130 15135.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15130-15135
-
-
Janssens, R.1
-
160
-
-
26844518737
-
Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens
-
Liu S, et al. Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens. J Immunol 2005 175:5067 5076.
-
(2005)
J Immunol
, vol.175
, pp. 5067-5076
-
-
Liu, S.1
-
161
-
-
17444424575
-
A role for nuclear factor kappa Brel transcription factors in the regulation of the recombinase activator genes
-
Verkoczy L, et al. A role for nuclear factor kappa Brel transcription factors in the regulation of the recombinase activator genes. Immunity 2005 22:519 531.
-
(2005)
Immunity
, vol.22
, pp. 519-531
-
-
Verkoczy, L.1
-
162
-
-
34248216554
-
Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection
-
Verkoczy L, et al. Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection. J Immunol 2007 178:6332 6341.
-
(2007)
J Immunol
, vol.178
, pp. 6332-6341
-
-
Verkoczy, L.1
-
163
-
-
0031019217
-
Changes in locus-specific V(D)J recombinase activity induced by immunoglobulin gene products during B cell development
-
Constantinescu A, Schlissel MS. Changes in locus-specific V(D)J recombinase activity induced by immunoglobulin gene products during B cell development. J Exp Med 1997 185:609 620.
-
(1997)
J Exp Med
, vol.185
, pp. 609-620
-
-
Constantinescu, A.1
Schlissel, M.S.2
-
164
-
-
5044220453
-
A stepwise epigenetic process controls immunoglobulin allelic exclusion
-
Bergman Y, Cedar H. A stepwise epigenetic process controls immunoglobulin allelic exclusion. Nat Rev Immunol 2004 4:753 761.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 753-761
-
-
Bergman, Y.1
Cedar, H.2
-
165
-
-
33846438984
-
Igkappa allelic inclusion is a consequence of receptor editing
-
Casellas R, Zhang Q, Zheng NY, Mathias MD, Smith K, Wilson PC. Igkappa allelic inclusion is a consequence of receptor editing. J Exp Med 2007 204:153 160.
-
(2007)
J Exp Med
, vol.204
, pp. 153-160
-
-
Casellas, R.1
Zhang, Q.2
Zheng, N.Y.3
Mathias, M.D.4
Smith, K.5
Wilson, P.C.6
-
166
-
-
16544395692
-
Autoreactivity and allelic inclusion in a B cell nuclear transfer mouse
-
Gerdes T, Wabl M. Autoreactivity and allelic inclusion in a B cell nuclear transfer mouse. Nat Immunol 2004 5:1282 1287.
-
(2004)
Nat Immunol
, vol.5
, pp. 1282-1287
-
-
Gerdes, T.1
Wabl, M.2
-
167
-
-
0041732283
-
The nonimmunoglobulin portion of lambda5 mediates cell-autonomous pre-B cell receptor signaling
-
Ohnishi K, Melchers F. The nonimmunoglobulin portion of lambda5 mediates cell-autonomous pre-B cell receptor signaling. Nat Immunol 2003 4:849 856.
-
(2003)
Nat Immunol
, vol.4
, pp. 849-856
-
-
Ohnishi, K.1
Melchers, F.2
-
168
-
-
0025955367
-
Heparin alters the expression of different forms of immunoglobulin mu heavy chains and their associated proteins by pre-B cell lines and normal Ly-1 (CD5+) B cells
-
Chen J, Herzenberg LA, Herzenberg LA. Heparin alters the expression of different forms of immunoglobulin mu heavy chains and their associated proteins by pre-B cell lines and normal Ly-1 (CD5+) B cells. Int Immunol 1991 3:1117 1127.
-
(1991)
Int Immunol
, vol.3
, pp. 1117-1127
-
-
Chen, J.1
Herzenberg, L.A.2
Herzenberg, L.A.3
-
169
-
-
51549120217
-
A unique role for the lambda5 nonimmunoglobulin tail in early B lymphocyte development
-
Vettermann C, Herrmann K, Albert C, Roth E, Bosl MR, Jack HM. A unique role for the lambda5 nonimmunoglobulin tail in early B lymphocyte development. J Immunol 2008 181:3232 3242.
-
(2008)
J Immunol
, vol.181
, pp. 3232-3242
-
-
Vettermann, C.1
Herrmann, K.2
Albert, C.3
Roth, E.4
Bosl, M.R.5
Jack, H.M.6
-
170
-
-
0026721377
-
Exclusion and inclusion of alpha and beta T cell receptor alleles
-
Borgulya P, Kishi H, Uematsu Y, von Boehmer H. Exclusion and inclusion of alpha and beta T cell receptor alleles. Cell 1992 69:529 537.
-
(1992)
Cell
, vol.69
, pp. 529-537
-
-
Borgulya, P.1
Kishi, H.2
Uematsu, Y.3
Von Boehmer, H.4
-
171
-
-
0024294021
-
The joining of germ-line v alpha to J alpha genes replaces the preexisting v alpha-J alpha complexes in a T cell receptor alpha, beta positive T cell line
-
Marolleau JP, et al. The joining of germ-line V alpha to J alpha genes replaces the preexisting V alpha-J alpha complexes in a T cell receptor alpha, beta positive T cell line. Cell 1988 55:291 300.
-
(1988)
Cell
, vol.55
, pp. 291-300
-
-
Marolleau, J.P.1
-
172
-
-
0025791952
-
T cell receptor genes in a series of class i major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: Implications for T cell allelic exclusion and antigen-specific repertoire
-
Casanova JL, Romero P, Widmann C, Kourilsky P, Maryanski JL. T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire. J Exp Med 1991 174:1371 1383.
-
(1991)
J Exp Med
, vol.174
, pp. 1371-1383
-
-
Casanova, J.L.1
Romero, P.2
Widmann, C.3
Kourilsky, P.4
Maryanski, J.L.5
-
173
-
-
0027422750
-
Expression of two T cell receptor alpha chains: Dual receptor T cells
-
Padovan E, Casorati G, Dellabona P, Meyer S, Brockhaus M, Lanzavecchia A. Expression of two T cell receptor alpha chains: dual receptor T cells. Science 1993 262:422 424.
-
(1993)
Science
, vol.262
, pp. 422-424
-
-
Padovan, E.1
Casorati, G.2
Dellabona, P.3
Meyer, S.4
Brockhaus, M.5
Lanzavecchia, A.6
-
174
-
-
0027451442
-
Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice
-
Heath WR, Miller JF. Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice. J Exp Med 1993 178:1807 1811.
-
(1993)
J Exp Med
, vol.178
, pp. 1807-1811
-
-
Heath, W.R.1
Miller, J.F.2
-
175
-
-
0029037740
-
Expression of two T cell receptor alpha chains on the surface of normal murine T cells
-
Heath WR, Carbone FR, Bertolino P, Kelly J, Cose S, Miller JF. Expression of two T cell receptor alpha chains on the surface of normal murine T cells. Eur J Immunol 1995 25:1617 1623.
-
(1995)
Eur J Immunol
, vol.25
, pp. 1617-1623
-
-
Heath, W.R.1
Carbone, F.R.2
Bertolino, P.3
Kelly, J.4
Cose, S.5
Miller, J.F.6
-
176
-
-
0011955092
-
Deletions of kappa chain constant region genes in mouse lambda chain-producing B cells involve intrachromosomal DNA recombinations similar to V-J joining
-
Moore MW, Durdik J, Persiani DM, Selsing E. Deletions of kappa chain constant region genes in mouse lambda chain-producing B cells involve intrachromosomal DNA recombinations similar to V-J joining. Proc Natl Acad Sci USA 1985 82:6211 6215.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 6211-6215
-
-
Moore, M.W.1
Durdik, J.2
Persiani, D.M.3
Selsing, E.4
-
177
-
-
0025093522
-
Murine lambda gene rearrangements: The stochastic model prevails over the ordered model
-
Nadel B, Cazenave PA, Sanchez P. Murine lambda gene rearrangements: the stochastic model prevails over the ordered model. EMBO J 1990 9:435 440.
-
(1990)
EMBO J
, vol.9
, pp. 435-440
-
-
Nadel, B.1
Cazenave, P.A.2
Sanchez, P.3
-
178
-
-
0027447365
-
Gene targeting in the Ig kappa locus: Efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa
-
Zou YR, Takeda S, Rajewsky K. Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa. EMBO J 1993 12:811 820.
-
(1993)
EMBO J
, vol.12
, pp. 811-820
-
-
Zou, Y.R.1
Takeda, S.2
Rajewsky, K.3
-
179
-
-
0032487518
-
Receptor editing occurs frequently during normal B cell development
-
Retter MW, Nemazee D. Receptor editing occurs frequently during normal B cell development. J Exp Med 1998 188:1231 1238.
-
(1998)
J Exp Med
, vol.188
, pp. 1231-1238
-
-
Retter, M.W.1
Nemazee, D.2
-
180
-
-
33748992038
-
Receptor editing in lymphocyte development and central tolerance
-
Nemazee D. Receptor editing in lymphocyte development and central tolerance. Nat Rev Immunol 2006 6:728 740.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 728-740
-
-
Nemazee, D.1
-
181
-
-
39149143650
-
Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production
-
Vela JL, Ait-Azzouzene D, Duong BH, Ota T, Nemazee D. Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production. Immunity 2008 28:161 170.
-
(2008)
Immunity
, vol.28
, pp. 161-170
-
-
Vela, J.L.1
Ait-Azzouzene, D.2
Duong, B.H.3
Ota, T.4
Nemazee, D.5
-
182
-
-
0020468006
-
Amplification of immunoglobulin lambda constant genes in populations of wild mice
-
Scott CL, Mushinski JF, Huppi K, Weigert M, Potter M. Amplification of immunoglobulin lambda constant genes in populations of wild mice. Nature 1982 300:757 760.
-
(1982)
Nature
, vol.300
, pp. 757-760
-
-
Scott, C.L.1
Mushinski, J.F.2
Huppi, K.3
Weigert, M.4
Potter, M.5
-
183
-
-
0024566249
-
A linkage map of the mouse immunoglobulin lambda light chain locus
-
Carson S, Wu GE. A linkage map of the mouse immunoglobulin lambda light chain locus. Immunogenetics 1989 29:173 179.
-
(1989)
Immunogenetics
, vol.29
, pp. 173-179
-
-
Carson, S.1
Wu, G.E.2
-
184
-
-
0025730210
-
V lambda-J lambda rearrangements are restricted within a V-J-C recombination unit in the mouse
-
Sanchez P, Nadel B, Cazenave PA. V lambda-J lambda rearrangements are restricted within a V-J-C recombination unit in the mouse. Eur J Immunol 1991 21:907 911.
-
(1991)
Eur J Immunol
, vol.21
, pp. 907-911
-
-
Sanchez, P.1
Nadel, B.2
Cazenave, P.A.3
-
185
-
-
0025788230
-
Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain
-
Ramsden DA, Wu GE. Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain. Proc Natl Acad Sci USA 1991 88:10721 10725.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10721-10725
-
-
Ramsden, D.A.1
Wu, G.E.2
-
186
-
-
0033181345
-
Four of five RAG-expressing JCkappa- small pre-BII cells have no L chain gene rearrangements: Detection by high-efficiency single cell PCR
-
Yamagami T, ten Boekel E, Schaniel C, Andersson J, Rolink A, Melchers F. Four of five RAG-expressing JCkappa- small pre-BII cells have no L chain gene rearrangements: detection by high-efficiency single cell PCR. Immunity 1999 11:309 316.
-
(1999)
Immunity
, vol.11
, pp. 309-316
-
-
Yamagami, T.1
Ten Boekel, E.2
Schaniel, C.3
Andersson, J.4
Rolink, A.5
Melchers, F.6
-
187
-
-
0024362521
-
Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene
-
Hagman J, et al. Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene. J Exp Med 1989 169:1911 1929.
-
(1989)
J Exp Med
, vol.169
, pp. 1911-1929
-
-
Hagman, J.1
-
188
-
-
0024523366
-
Isotype exclusion and transgene down-regulation in immunoglobulin-lambda transgenic mice
-
Neuberger MS, Caskey HM, Pettersson S, Williams GT, Surani MA. Isotype exclusion and transgene down-regulation in immunoglobulin-lambda transgenic mice. Nature 1989 338:350 352.
-
(1989)
Nature
, vol.338
, pp. 350-352
-
-
Neuberger, M.S.1
Caskey, H.M.2
Pettersson, S.3
Williams, G.T.4
Surani, M.A.5
-
189
-
-
33746595677
-
Consequences of receptor editing at the lambda locus: Multireactivity and light chain secretion
-
Doyle CM, Han J, Weigert MG, Prak ET. Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion. Proc Natl Acad Sci USA 2006 103:11264 11269.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11264-11269
-
-
Doyle, C.M.1
Han, J.2
Weigert, M.G.3
Prak, E.T.4
-
190
-
-
0037121975
-
Anti-DNA B cells in MRLlpr mice show altered differentiation and editing pattern
-
Li Y, Li H, Ni D, Weigert M. Anti-DNA B cells in MRLlpr mice show altered differentiation and editing pattern. J Exp Med 2002 196:1543 1552.
-
(2002)
J Exp Med
, vol.196
, pp. 1543-1552
-
-
Li, Y.1
Li, H.2
Ni, D.3
Weigert, M.4
-
191
-
-
0037148509
-
Autoreactive B cells in the marginal zone that express dual receptors
-
Li Y, Li H, Weigert M. Autoreactive B cells in the marginal zone that express dual receptors. J Exp Med 2002 195:181 188.
-
(2002)
J Exp Med
, vol.195
, pp. 181-188
-
-
Li, Y.1
Li, H.2
Weigert, M.3
-
192
-
-
1342342916
-
Editing anti-DNA B cells by Vlambdax
-
Li Y, Louzoun Y, Weigert M. Editing anti-DNA B cells by Vlambdax. J Exp Med 2004 199:337 346.
-
(2004)
J Exp Med
, vol.199
, pp. 337-346
-
-
Li, Y.1
Louzoun, Y.2
Weigert, M.3
-
193
-
-
34548712495
-
Ig allotypic inclusion does not prevent B cell development or response
-
Velez MG, et al. Ig allotypic inclusion does not prevent B cell development or response. J Immunol 2007 179:1049 1057.
-
(2007)
J Immunol
, vol.179
, pp. 1049-1057
-
-
Velez, M.G.1
-
194
-
-
7444270297
-
One neuron-one receptor rule in the mouse olfactory system
-
Serizawa S, Miyamichi K, Sakano H. One neuron-one receptor rule in the mouse olfactory system. Trends Genet 2004 20:648 653.
-
(2004)
Trends Genet
, vol.20
, pp. 648-653
-
-
Serizawa, S.1
Miyamichi, K.2
Sakano, H.3
-
195
-
-
0023235280
-
Allelic exclusion frequency analysis and molecular characteristics of immunoglobulins secreted by the hybridomas expressing both allelic genes
-
Cherepakhin VV, Jackubov LZ, Ibraghimov AR, Rokhlin OV. Allelic exclusion frequency analysis and molecular characteristics of immunoglobulins secreted by the hybridomas expressing both allelic genes. Immunol Lett 1987 15:33 39.
-
(1987)
Immunol Lett
, vol.15
, pp. 33-39
-
-
Cherepakhin, V.V.1
Jackubov, L.Z.2
Ibraghimov, A.R.3
Rokhlin, O.V.4
-
196
-
-
0032076047
-
Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors
-
Sarukhan A, Garcia C, Lanoue A, von Boehmer H. Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors. Immunity 1998 8:563 570.
-
(1998)
Immunity
, vol.8
, pp. 563-570
-
-
Sarukhan, A.1
Garcia, C.2
Lanoue, A.3
Von Boehmer, H.4
-
197
-
-
33645856486
-
Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation
-
Paus D, Phan TG, Chan TD, Gardam S, Basten A, Brink R. Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation. J Exp Med 2006 203:1081 1091.
-
(2006)
J Exp Med
, vol.203
, pp. 1081-1091
-
-
Paus, D.1
Phan, T.G.2
Chan, T.D.3
Gardam, S.4
Basten, A.5
Brink, R.6
-
198
-
-
1542377328
-
B cell receptor signal strength determines B cell fate
-
Casola S, et al. B cell receptor signal strength determines B cell fate. Nat Immunol 2004 5:317 327.
-
(2004)
Nat Immunol
, vol.5
, pp. 317-327
-
-
Casola, S.1
-
199
-
-
0027174495
-
Affinity maturation leads to differential expression of multiple copies of a kappa light-chain transgene
-
Lozano F, Rada C, Jarvis JM, Milstein C. Affinity maturation leads to differential expression of multiple copies of a kappa light-chain transgene. Nature 1993 363:271 273.
-
(1993)
Nature
, vol.363
, pp. 271-273
-
-
Lozano, F.1
Rada, C.2
Jarvis, J.M.3
Milstein, C.4
-
200
-
-
67650457059
-
Mechanisms promoting translocations in editing and switching peripheral B cells
-
Wang JH, et al. Mechanisms promoting translocations in editing and switching peripheral B cells. Nature 2009 460:231 236.
-
(2009)
Nature
, vol.460
, pp. 231-236
-
-
Wang, J.H.1
-
201
-
-
0030764978
-
V(D)J recombinase activity in a subset of germinal center B lymphocytes
-
Han S, Dillon SR, Zheng B, Shimoda M, Schlissel MS, Kelsoe G. V(D)J recombinase activity in a subset of germinal center B lymphocytes. Science 1997 278:301 305.
-
(1997)
Science
, vol.278
, pp. 301-305
-
-
Han, S.1
Dillon, S.R.2
Zheng, B.3
Shimoda, M.4
Schlissel, M.S.5
Kelsoe, G.6
-
202
-
-
0030803748
-
V(D)J recombination in mature B cells: A mechanism for altering antibody responses
-
Papavasiliou F, et al. V(D)J recombination in mature B cells: a mechanism for altering antibody responses. Science 1997 278:298 301.
-
(1997)
Science
, vol.278
, pp. 298-301
-
-
Papavasiliou, F.1
-
203
-
-
0030460833
-
Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells
-
Han S, Zheng B, Schatz DG, Spanopoulou E, Kelsoe G. Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. Science 1996 274:2094 2097.
-
(1996)
Science
, vol.274
, pp. 2094-2097
-
-
Han, S.1
Zheng, B.2
Schatz, D.G.3
Spanopoulou, E.4
Kelsoe, G.5
-
204
-
-
0024473375
-
Only DFL16, DSP2, and DQ52 gene families exist in mouse immunoglobulin heavy chain diversity gene loci, of which DFL16 and DSP2 originate from the same primordial DH gene
-
Ichihara Y, Hayashida H, Miyazawa S, Kurosawa Y. Only DFL16, DSP2, and DQ52 gene families exist in mouse immunoglobulin heavy chain diversity gene loci, of which DFL16 and DSP2 originate from the same primordial DH gene. Eur J Immunol 1989 19:1849 1854.
-
(1989)
Eur J Immunol
, vol.19
, pp. 1849-1854
-
-
Ichihara, Y.1
Hayashida, H.2
Miyazawa, S.3
Kurosawa, Y.4
-
205
-
-
0025758239
-
B cell development regulated by gene rearrangement: Arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames
-
Gu H, Kitamura D, Rajewsky K. B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames. Cell 1991 65:47 54.
-
(1991)
Cell
, vol.65
, pp. 47-54
-
-
Gu, H.1
Kitamura, D.2
Rajewsky, K.3
-
206
-
-
0030765923
-
Changes in the V(H) gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor
-
ten Boekel E, Melchers F, Rolink AG. Changes in the V(H) gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor. Immunity 1997 7:357 368.
-
(1997)
Immunity
, vol.7
, pp. 357-368
-
-
Ten Boekel, E.1
Melchers, F.2
Rolink, A.G.3
|