H3K4me3 Stimulates the V(D)J RAG Complex for Both Nicking and Hairpinning in trans in Addition to Tethering in cis: Implications for Translocations

Molecular Cell

Volumn 34, Issue 5, 2009, Pages 535-544

  Shimazaki, Noriko ^a   Tsai, Albert G ^a   Lieber, Michael R ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

DNA; PROTEINS

Indexed keywords

HISTONE; HISTONE H3K4ME3; RAG2 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHROMOSOME TRANSLOCATION; COMPLEX FORMATION; CONTROLLED STUDY; DNA NICK TRANSLATION; ENZYME ACTIVITY; METHYLATION; POINT MUTATION; PROTEIN BINDING; VDJ EXON;

ANIMALS; BINDING SITES; DNA BREAKS, SINGLE-STRANDED; DNA-BINDING PROTEINS; HISTONES; INVERTED REPEAT SEQUENCES; METHYLATION; MICE; MODELS, GENETIC; POINT MUTATION; RECOMBINATION, GENETIC; SUBSTRATE SPECIFICITY; TRANSLOCATION, GENETIC;

EID: 66749124789     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.05.011     Document Type: Article

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