메뉴 건너뛰기




Volumn 90, Issue 6, 1997, Pages 1073-1083

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

EID: 0342711256     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80373-6     Document Type: Article
Times cited : (953)

References (53)
  • 1
    • 0025811882 scopus 로고
    • The SCID mouse mutant: Definition, characterization, and potential uses
    • Bosma, M.J., and Carroll, A.M. (1991). The SCID mouse mutant: definition, characterization, and potential uses. Annu. Rev. Immunol. 9, 323-350.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 323-350
    • Bosma, M.J.1    Carroll, A.M.2
  • 2
    • 0029003671 scopus 로고
    • Transitional B cells are the target of negative selection in the B cell compartment
    • Carsetti, R., Köhler, G., and Lamers, M.C. (1995). Transitional B cells are the target of negative selection in the B cell compartment. J. Exp. Med. 181, 2129-2140.
    • (1995) J. Exp. Med. , vol.181 , pp. 2129-2140
    • Carsetti, R.1    Köhler, G.2    Lamers, M.C.3
  • 3
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • Cyster, J.G., Hartley, S.B., and Goodnow, C.C. (1994). Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 371, 389-395.
    • (1994) Nature , vol.371 , pp. 389-395
    • Cyster, J.G.1    Hartley, S.B.2    Goodnow, C.C.3
  • 5
    • 0030265732 scopus 로고    scopus 로고
    • Ig light chains are secreted predominantly as monomers
    • Dul, J.L., Aviel, S., Melnick, J., and Argon, Y. (1996). Ig light chains are secreted predominantly as monomers. J. Immunol. 157, 2969-2975.
    • (1996) J. Immunol. , vol.157 , pp. 2969-2975
    • Dul, J.L.1    Aviel, S.2    Melnick, J.3    Argon, Y.4
  • 6
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay, D., Saunders, T., Camper, S., and Weigert, M. (1993). Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177, 999-1008.
    • (1993) J. Exp. Med. , vol.177 , pp. 999-1008
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 7
    • 0029913115 scopus 로고    scopus 로고
    • Regulation of an early developmental checkpoint in the B cell pathway by Igβ
    • Gong, S., and Nussenzweig, M.C. (1996). Regulation of an early developmental checkpoint in the B cell pathway by Igβ. Science 272, 411-414.
    • (1996) Science , vol.272 , pp. 411-414
    • Gong, S.1    Nussenzweig, M.C.2
  • 9
    • 0027280936 scopus 로고
    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
    • Gu, H., Zou, Y.R., and Rajewsky, K. (1993). Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73, 1155-1164.
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.R.2    Rajewsky, K.3
  • 10
    • 0030460833 scopus 로고    scopus 로고
    • Neoteny in lymphocytes: Rag1 and rag2 expression in germinal center B cells
    • Han, S., Zheng, B., Schatz, D.G., Spanopoulou, E., and Kelsoe, G. (1996). Neoteny in lymphocytes: rag1 and rag2 expression in germinal center B cells. Science 274, 2094-2097.
    • (1996) Science , vol.274 , pp. 2094-2097
    • Han, S.1    Zheng, B.2    Schatz, D.G.3    Spanopoulou, E.4    Kelsoe, G.5
  • 11
    • 0027447188 scopus 로고
    • Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
    • Hartley, S.B., Cooke, M.P., Fulcher, D.A., Harris, A.W., Cory, S., Basten, A., and Goodnow, C.C. (1993). Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell 72, 325-335.
    • (1993) Cell , vol.72 , pp. 325-335
    • Hartley, S.B.1    Cooke, M.P.2    Fulcher, D.A.3    Harris, A.W.4    Cory, S.5    Basten, A.6    Goodnow, C.C.7
  • 12
    • 0030475466 scopus 로고    scopus 로고
    • Reexpression of rag-1 and rag-2 genes in activated mature mouse B cells
    • Hikida, M., Mori, M., Takai, T., Tomochika, K., Hamatani, K., and Ohmori, H. (1996). Reexpression of rag-1 and rag-2 genes in activated mature mouse B cells. Science 274, 2092-2094.
    • (1996) Science , vol.274 , pp. 2092-2094
    • Hikida, M.1    Mori, M.2    Takai, T.3    Tomochika, K.4    Hamatani, K.5    Ohmori, H.6
  • 14
    • 0022616253 scopus 로고
    • Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defense strategy
    • Kärre, K., Ljunggren, H.G., Piontek, G., and Kiessling, R. (1986). Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defense strategy. Nature 319, 675-678.
    • (1986) Nature , vol.319 , pp. 675-678
    • Kärre, K.1    Ljunggren, H.G.2    Piontek, G.3    Kiessling, R.4
  • 15
    • 0028872616 scopus 로고
    • Development and selection of T cells: Facts and puzzles
    • Kisielow, P., and von Boehmer, H. (1995). Development and selection of T cells: facts and puzzles. Adv. Immunol. 58, 87-209.
    • (1995) Adv. Immunol. , vol.58 , pp. 87-209
    • Kisielow, P.1    Von Boehmer, H.2
  • 17
    • 0025852445 scopus 로고
    • A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene
    • Kitamura, D., Roes, J., Kühn, R., and Rajewsky, K. (1991). A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature 350, 423-426.
    • (1991) Nature , vol.350 , pp. 423-426
    • Kitamura, D.1    Roes, J.2    Kühn, R.3    Rajewsky, K.4
  • 18
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on b cells undergoing apoptosis
    • Koopman, G., Reutelingsperger, C.P.M., Kuijten, G.A.M., Keehnen, R.M.J., Pals, ST., and van Oers, M.H.J. (1994). Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84, 1415-1420.
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.M.2    Kuijten, G.A.M.3    Keehnen, R.M.J.4    Pals, S.T.5    Van Oers, M.H.J.6
  • 19
    • 0029155706 scopus 로고
    • Inducible gene targeting in mice
    • Kühn, R., Schwenk, F., Aguet, M., and Rajewsky, K. (1995). Inducible gene targeting in mice. Science 269, 1427-1429.
    • (1995) Science , vol.269 , pp. 1427-1429
    • Kühn, R.1    Schwenk, F.2    Aguet, M.3    Rajewsky, K.4
  • 20
    • 0029913687 scopus 로고    scopus 로고
    • Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/fas-mediated apoptosis
    • Lagresle, C., Mondiere, P., Bella, C., Krammer, P.M., and Defrance, T. (1996). Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/fas-mediated apoptosis. J. Exp. Med. 183, 1377-1388.
    • (1996) J. Exp. Med. , vol.183 , pp. 1377-1388
    • Lagresle, C.1    Mondiere, P.2    Bella, C.3    Krammer, P.M.4    Defrance, T.5
  • 21
    • 0025880648 scopus 로고
    • MHC class I deficiency: Susceptibility to natural killer (NK) cells and impaired NK activity
    • Liao, N.-S., Bix, M., Zijilstra, M., Jaenisch, R., and Raulet, D. (1991). MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253, 199-202.
    • (1991) Science , vol.253 , pp. 199-202
    • Liao, N.-S.1    Bix, M.2    Zijilstra, M.3    Jaenisch, R.4    Raulet, D.5
  • 22
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin, S., Reutelingsperger, C., McGahon, A., Rader, J., van Schie, R., LaFace, D., and Green, D. (1995). Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182, 1545-1556.
    • (1995) J. Exp. Med. , vol.182 , pp. 1545-1556
    • Martin, S.1    Reutelingsperger, C.2    McGahon, A.3    Rader, J.4    Van Schie, R.5    LaFace, D.6    Green, D.7
  • 23
    • 0024521441 scopus 로고
    • bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation
    • McDonnell, T.J., Deane, N., Platt, F.M., Nunez, G., Jaeger, U., Mckearn, J.P., and Korsmeyer, S.J. (1989). bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 57, 79-88.
    • (1989) Cell , vol.57 , pp. 79-88
    • McDonnell, T.J.1    Deane, N.2    Platt, F.M.3    Nunez, G.4    Jaeger, U.5    McKearn, J.P.6    Korsmeyer, S.J.7
  • 24
    • 0026317875 scopus 로고
    • Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting
    • Mombaerts, P., Clarke, A.R., Hooper, M.L., and Tonegawa, S. (1991). Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting. Proc. Natl. Acad. Sci. USA 88, 3084-3087.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3084-3087
    • Mombaerts, P.1    Clarke, A.R.2    Hooper, M.L.3    Tonegawa, S.4
  • 26
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata, S., and Golstein, P. (1995). The Fas death factor. Science 267, 1449-1456.
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 27
    • 0030249394 scopus 로고    scopus 로고
    • A prematurely expressed Igk transgene, but not a VkJk gene segment targeted into the Igk locus, can rescue B cell development in λ5-deficient mice
    • Pelanda, R., Schaal, S., Torres, R.M., and Rajewsky, K. (1996). A prematurely expressed Igk transgene, but not a VkJk gene segment targeted into the Igk locus, can rescue B cell development in λ5-deficient mice. Immunity 5, 229-239.
    • (1996) Immunity , vol.5 , pp. 229-239
    • Pelanda, R.1    Schaal, S.2    Torres, R.M.3    Rajewsky, K.4
  • 28
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky, K. (1996). Clonal selection and learning in the antibody system. Nature 381, 751-758.
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 29
    • 0029076561 scopus 로고
    • CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells
    • Rathmell, J.C., Cooke, M.P., Ho, W.Y., Grein, J., Townsend, S.E., Davis, M.M., and Goodnow, C.C. (1995). CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. Nature 376, 181-184.
    • (1995) Nature , vol.376 , pp. 181-184
    • Rathmell, J.C.1    Cooke, M.P.2    Ho, W.Y.3    Grein, J.4    Townsend, S.E.5    Davis, M.M.6    Goodnow, C.C.7
  • 30
    • 0030592564 scopus 로고    scopus 로고
    • Expansion or elimination of B cells in vivo: Dual roles for CD40-and Fas (CD95)-ligands modulated by the B cell antigen receptor
    • Rathmell, J.C., Townsend, S.E., Xu, J., Flavell, R.A., and Goodnow, C.C. (1996). Expansion or elimination of B cells in vivo: dual roles for CD40-and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 87, 319-329.
    • (1996) Cell , vol.87 , pp. 319-329
    • Rathmell, J.C.1    Townsend, S.E.2    Xu, J.3    Flavell, R.A.4    Goodnow, C.C.5
  • 31
    • 0018179467 scopus 로고
    • Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response
    • Reth, M., Hämmerling, G.J., and Rajewsky, K. (1978). Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response. Eur. J. Immunol. 8, 393-400.
    • (1978) Eur. J. Immunol. , vol.8 , pp. 393-400
    • Reth, M.1    Hämmerling, G.J.2    Rajewsky, K.3
  • 32
    • 0018578942 scopus 로고
    • Analysis of the repertoire of anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in C57BL/6 mice by cell fusion. II. Characterization of idiotypes by monoclonal anti-idiotope antibodies
    • Reth, M., Imanishi-Kari, T., and Rajewsky, K. (1979). Analysis of the repertoire of anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in C57BL/6 mice by cell fusion. II. Characterization of idiotypes by monoclonal anti-idiotope antibodies. Eur. J. Immunol. 9, 1004-1013.
    • (1979) Eur. J. Immunol. , vol.9 , pp. 1004-1013
    • Reth, M.1    Imanishi-Kari, T.2    Rajewsky, K.3
  • 33
    • 0030890949 scopus 로고    scopus 로고
    • Initiation and processing of signals from the B cell antigen receptor
    • Reth, M., and Wienands, J. (1997). Initiation and processing of signals from the B cell antigen receptor. Annu. Rev. Immunol. 15, 453-479.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 453-479
    • Reth, M.1    Wienands, J.2
  • 34
  • 35
    • 0028176654 scopus 로고
    • Heavy-chain directed B-cell maturation: Continuous clonal selection beginning at the pre-B cell stage
    • Schwartz, R.S., and Stollar, B.D. (1994). Heavy-chain directed B-cell maturation: continuous clonal selection beginning at the pre-B cell stage. Immunol. Today 15, 27-32.
    • (1994) Immunol. Today , vol.15 , pp. 27-32
    • Schwartz, R.S.1    Stollar, B.D.2
  • 36
    • 0029566108 scopus 로고
    • A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
    • Schwenk, F., Baron, U., and Rajewsky, K. (1995). A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res. 23, 5080-5081.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 5080-5081
    • Schwenk, F.1    Baron, U.2    Rajewsky, K.3
  • 40
    • 0028297141 scopus 로고
    • Bcl-2 expression promotes B-but not T-lymphoid development in scid mice
    • Strasser, A., Harris, A.W., Corcoran, L.M., and Gory, S. (1994). Bcl-2 expression promotes B-but not T-lymphoid development in scid mice. Nature 368, 457-460.
    • (1994) Nature , vol.368 , pp. 457-460
    • Strasser, A.1    Harris, A.W.2    Corcoran, L.M.3    Gory, S.4
  • 44
    • 0027691148 scopus 로고
    • Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus
    • Taki, S., Meiering, M., and Rajewsky, K. (1993). Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus. Science 262, 1268-1271.
    • (1993) Science , vol.262 , pp. 1268-1271
    • Taki, S.1    Meiering, M.2    Rajewsky, K.3
  • 45
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone marrow B cells
    • Tiegs, S.L., Russell, D.M., and Nemazee, D. (1993). Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177, 1009-1020.
    • (1993) J. Exp. Med. , vol.177 , pp. 1009-1020
    • Tiegs, S.L.1    Russell, D.M.2    Nemazee, D.3
  • 46
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. (1983). Somatic generation of antibody diversity. Nature 302, 575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 47
    • 0030058466 scopus 로고    scopus 로고
    • Aberrant B cell development and immune response in mice with a compromised B cell antigen receptor
    • Torres, M., Flaswinkel, H., Reth, M., and Rajewsky, K. (1996). Aberrant B cell development and immune response in mice with a compromised B cell antigen receptor. Science 272, 1804-1808.
    • (1996) Science , vol.272 , pp. 1804-1808
    • Torres, M.1    Flaswinkel, H.2    Reth, M.3    Rajewsky, K.4
  • 49
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux, D.L., Gory, S., and Adams, J.M. (1988). Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335, 440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Gory, S.2    Adams, J.M.3
  • 50
  • 53
    • 0030939476 scopus 로고    scopus 로고
    • Constitutive Bcl-2 expression during immunoglobulin heavy chain-promoted B cell differentiation expands novel precursor B cells
    • Young, F., Mizoguchi, E., Bhan, A.K., and Alt, F.W. (1997). Constitutive Bcl-2 expression during immunoglobulin heavy chain-promoted B cell differentiation expands novel precursor B cells. Immunity 6, 23-33.
    • (1997) Immunity , vol.6 , pp. 23-33
    • Young, F.1    Mizoguchi, E.2    Bhan, A.K.3    Alt, F.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.