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We thank B. Van Ness for providing us the pSPIg8 plasmid; R. Kühn for the E14 1 ES clone; A Egert for advice and technical help; C. Steinberg for helpful comments and critical reading of the manuscript, R. Torres, Y.-R. Zou, F Huetz, and L Quint for encouragements and discussions; J.-P. De Villartay for phosphorimager quantifications; S. Schaal for bone marrow analysis; and C. Garcia for cell sorting experiments. This work was partly supported by a short-term European Molecular Biology Organization fellowship
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