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Volumn 5, Issue 3, 2004, Pages 317-327

B cell receptor signal strength determines B cell fate

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; PROTEIN LMP2A; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS PROTEIN; EBV ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN BARR VIRUS; EBV-ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN-BARR VIRUS; LYMPHOCYTE ANTIGEN RECEPTOR; MATRIX PROTEIN;

EID: 1542377328     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1036     Document Type: Article
Times cited : (486)

References (59)
  • 1
    • 0036217975 scopus 로고    scopus 로고
    • Origins and functions of B-1 cells with notes on the role of CD5
    • Berland, R. & Wortis, H.H. Origins and functions of B-1 cells with notes on the role of CD5. Annu. Rev. Immunol. 20, 253-300 (2002).
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 253-300
    • Berland, R.1    Wortis, H.H.2
  • 2
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky, K. Clonal selection and learning in the antibody system. Nature 381, 751-758 (1996).
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 4
    • 0035887189 scopus 로고    scopus 로고
    • Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow
    • Hao, Z. & Rajewsky, K. Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow. J. Exp. Med. 194, 1151-1164 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 1151-1164
    • Hao, Z.1    Rajewsky, K.2
  • 5
    • 0033697266 scopus 로고    scopus 로고
    • Monomeric and oligomeric complexes of the B cell antigen receptor
    • Schamel, W.W. & Reth, M. Monomeric and oligomeric complexes of the B cell antigen receptor. Immunity 13, 5-14 (2000).
    • (2000) Immunity , vol.13 , pp. 5-14
    • Schamel, W.W.1    Reth, M.2
  • 6
    • 0025267165 scopus 로고
    • The peritoneal Ly-1 (CD5) B cell repertoire is unique among murine B cell repertoires
    • Lalor, P.A. & Morahan, G. The peritoneal Ly-1 (CD5) B cell repertoire is unique among murine B cell repertoires. Eur. J. Immunol. 20, 485-492 (1990).
    • (1990) Eur. J. Immunol. , vol.20 , pp. 485-492
    • Lalor, P.A.1    Morahan, G.2
  • 7
    • 0033516689 scopus 로고    scopus 로고
    • Positive selection of natural autoreactive B cells
    • Hayakawa, K. et al. Positive selection of natural autoreactive B cells. Science 285, 113-116 (1999).
    • (1999) Science , vol.285 , pp. 113-116
    • Hayakawa, K.1
  • 8
    • 0036533387 scopus 로고    scopus 로고
    • Antigen-dependent B-cell development
    • Cariappa, A. & Pillai, S. Antigen-dependent B-cell development. Curr. Opin. Immunol. 14, 241-249 (2002).
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 241-249
    • Cariappa, A.1    Pillai, S.2
  • 9
    • 0035803539 scopus 로고    scopus 로고
    • Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis
    • Bannish, G., Fuentes-Panana, E.M., Cambier, J.C., Pear, W.S. & Monroe, J.G. Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis. J. Exp. Med. 194, 1583-1596 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 1583-1596
    • Bannish, G.1    Fuentes-Panana, E.M.2    Cambier, J.C.3    Pear, W.S.4    Monroe, J.G.5
  • 10
    • 0031053838 scopus 로고    scopus 로고
    • Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone
    • Chen, X., Martin, F., Forbush, K.A., Perlmutter, R.M. & Kearney, J.F. Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone. Int. Immunol. 9, 27-41 (1997).
    • (1997) Int. Immunol. , vol.9 , pp. 27-41
    • Chen, X.1    Martin, F.2    Forbush, K.A.3    Perlmutter, R.M.4    Kearney, J.F.5
  • 12
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M. et al. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102, 553-563 (2000).
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1
  • 13
    • 0033575778 scopus 로고    scopus 로고
    • B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development
    • Lam, K.P. & Rajewsky, K. B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development. J. Exp. Med. 190, 471-477 (1999).
    • (1999) J. Exp. Med. , vol.190 , pp. 471-477
    • Lam, K.P.1    Rajewsky, K.2
  • 14
    • 0033575755 scopus 로고    scopus 로고
    • Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment
    • Watanabe, N. et al. Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment. J. Exp. Med. 190, 461-469 (1999).
    • (1999) J. Exp. Med. , vol.190 , pp. 461-469
    • Watanabe, N.1
  • 15
    • 0035920563 scopus 로고    scopus 로고
    • Interference with immunoglobulin (Ig)α immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igβ cytoplasmic tail
    • Kraus, M. et al. Interference with immunoglobulin (Ig)α immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igβ cytoplasmic tail. J. Exp. Med. 194, 455-469 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 455-469
    • Kraus, M.1
  • 16
    • 0032169313 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals
    • Caldwell, R.G., Wilson, J.B., Anderson, S.J. & Longnecker, R. Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity 9, 405-411 (1998).
    • (1998) Immunity , vol.9 , pp. 405-411
    • Caldwell, R.G.1    Wilson, J.B.2    Anderson, S.J.3    Longnecker, R.4
  • 17
    • 0035126502 scopus 로고    scopus 로고
    • Epstein-Barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR
    • Dykstra, M.L., Longnecker, R. & Pierce, S.K. Epstein-Barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR. Immunity 14, 57-67 (2001).
    • (2001) Immunity , vol.14 , pp. 57-67
    • Dykstra, M.L.1    Longnecker, R.2    Pierce, S.K.3
  • 18
    • 0035817250 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module
    • Engels, N. et al. Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module. J. Exp. Med. 194, 255-264 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 255-264
    • Engels, N.1
  • 19
    • 0028970289 scopus 로고
    • Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases
    • Miller, C.L. et al. Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases. Immunity 2, 155-166 (1995).
    • (1995) Immunity , vol.2 , pp. 155-166
    • Miller, C.L.1
  • 20
    • 0030754766 scopus 로고    scopus 로고
    • The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction
    • Fruehling, S. & Longnecker, R. The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction. Virology 235, 241-251 (1997).
    • (1997) Virology , vol.235 , pp. 241-251
    • Fruehling, S.1    Longnecker, R.2
  • 21
    • 0035054944 scopus 로고    scopus 로고
    • Ontogeny, distribution and function of CD38-expressing B lymphocytes in mice
    • Donis-Hernandez, F.R., Parkhouse, R.M. & Santos-Argumedo, L. Ontogeny, distribution and function of CD38-expressing B lymphocytes in mice. Eur. J. Immunol. 31, 1261-1267 (2001).
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1261-1267
    • Donis-Hernandez, F.R.1    Parkhouse, R.M.2    Santos-Argumedo, L.3
  • 22
    • 0031661310 scopus 로고    scopus 로고
    • Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency
    • Fruehling, S., Swart, R., Dolwick, K.M., Kremmer, E. & Longnecker, R. Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency. J. Virol. 72, 7796-7806 (1998).
    • (1998) J. Virol. , vol.72 , pp. 7796-7806
    • Fruehling, S.1    Swart, R.2    Dolwick, K.M.3    Kremmer, E.4    Longnecker, R.5
  • 23
    • 0025902383 scopus 로고
    • The preference for switching to expression of the IgA isotype of antibody exhibited by B lymphocytes in Peyer's patches is likely due to intrinsic properties of their microenvironment
    • Cebra, J.J., Logan, A.C. & Weinstein, P.D. The preference for switching to expression of the IgA isotype of antibody exhibited by B lymphocytes in Peyer's patches is likely due to intrinsic properties of their microenvironment. Immunol. Res. 10, 393-395 (1991).
    • (1991) Immunol. Res. , vol.10 , pp. 393-395
    • Cebra, J.J.1    Logan, A.C.2    Weinstein, P.D.3
  • 24
    • 0031921084 scopus 로고    scopus 로고
    • The role of complement and complement receptors in induction and regulation of immunity
    • Carroll, M.C. The role of complement and complement receptors in induction and regulation of immunity. Annu. Rev. Immunol. 16, 545-568 (1998).
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 545-568
    • Carroll, M.C.1
  • 25
    • 0023729241 scopus 로고
    • Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
    • Goodnow, C.C. et al. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334, 676-682 (1988).
    • (1988) Nature , vol.334 , pp. 676-682
    • Goodnow, C.C.1
  • 26
    • 0031424315 scopus 로고    scopus 로고
    • Receptor editing in a transgenic mouse model: Site, efficiency, and role in B cell tolerance and antibody diversification
    • Pelanda, R. et al. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity 7, 765-775 (1997).
    • (1997) Immunity , vol.7 , pp. 765-775
    • Pelanda, R.1
  • 27
    • 0342711256 scopus 로고    scopus 로고
    • In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
    • Lam, K.P., Kuhn, R. & Rajewsky, K. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90, 1073-1083 (1997).
    • (1997) Cell , vol.90 , pp. 1073-1083
    • Lam, K.P.1    Kuhn, R.2    Rajewsky, K.3
  • 28
    • 0033808329 scopus 로고    scopus 로고
    • The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo
    • Merchant, M., Caldwell, R.G. & Longnecker, R. The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo. J. Virol. 74, 9115-9124 (2000).
    • (2000) J. Virol. , vol.74 , pp. 9115-9124
    • Merchant, M.1    Caldwell, R.G.2    Longnecker, R.3
  • 29
    • 0033919570 scopus 로고    scopus 로고
    • B-1 cells: The lineage question revisited
    • Herzenberg, L.A. B-1 cells: the lineage question revisited. Immunol. Rev 175, 9-22 (2000).
    • (2000) Immunol. Rev , vol.175 , pp. 9-22
    • Herzenberg, L.A.1
  • 30
    • 0032550355 scopus 로고    scopus 로고
    • B-1 cell development: Evidence for an uncommitted immunoglobulin (Ig)M+ B cell precursor in B-1 cell differentiation
    • Clarke, S.H. & Arnold, L.W. B-1 cell development: evidence for an uncommitted immunoglobulin (Ig)M+ B cell precursor in B-1 cell differentiation. J. Exp. Med. 187, 1325-1334 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 1325-1334
    • Clarke, S.H.1    Arnold, L.W.2
  • 31
    • 0037240911 scopus 로고    scopus 로고
    • Positive selection of anti-thy-1 autoreactive B-1 cells and natural serum autoantibody production independent from bone marrow B cell development
    • Hayakawa, K. et al. Positive selection of anti-thy-1 autoreactive B-1 cells and natural serum autoantibody production independent from bone marrow B cell development. J. Exp. Med. 197, 87-99 (2003).
    • (2003) J. Exp. Med. , vol.197 , pp. 87-99
    • Hayakawa, K.1
  • 32
    • 0036754302 scopus 로고    scopus 로고
    • Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses
    • Balazs, M., Martin, F., Zhou, T. & Kearney, J. Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 17, 341-352 (2002).
    • (2002) Immunity , vol.17 , pp. 341-352
    • Balazs, M.1    Martin, F.2    Zhou, T.3    Kearney, J.4
  • 33
    • 0035803468 scopus 로고    scopus 로고
    • Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen
    • Schneider, P. et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J. Exp. Med. 194, 1691-1697 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 1691-1697
    • Schneider, P.1
  • 34
    • 0035555027 scopus 로고    scopus 로고
    • Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses
    • Girkontaite, I. et al. Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses. Nat. Immunol. 2, 855-862 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 855-862
    • Girkontaite, I.1
  • 35
    • 0034232062 scopus 로고    scopus 로고
    • Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response
    • Guinamard, R., Okigaki, M., Schlessinger, J. & Ravetch, J.V. Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat. Immunol. 1, 31-36 (2000).
    • (2000) Nat. Immunol. , vol.1 , pp. 31-36
    • Guinamard, R.1    Okigaki, M.2    Schlessinger, J.3    Ravetch, J.V.4
  • 36
    • 0037135158 scopus 로고    scopus 로고
    • Integrin-mediated long-term B cell retention in the splenic marginal zone
    • Lu, T.T. & Cyster, J.G. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 297, 409-412 (2002).
    • (2002) Science , vol.297 , pp. 409-412
    • Lu, T.T.1    Cyster, J.G.2
  • 37
    • 0038742790 scopus 로고    scopus 로고
    • Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development
    • Saito, T. et al. Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development. Immunity 18, 675-685 (2003).
    • (2003) Immunity , vol.18 , pp. 675-685
    • Saito, T.1
  • 38
    • 0037404527 scopus 로고    scopus 로고
    • Itchy, a Nedd4 ubiquitin ligase, downregulates latent membrane protein 2A activity in B-cell signaling
    • Ikeda, A., Caldwell, R.G., Longnecker, R. & Ikeda, M. Itchy, a Nedd4 ubiquitin ligase, downregulates latent membrane protein 2A activity in B-cell signaling. J. Virol. 77, 5529-5534 (2003).
    • (2003) J. Virol. , vol.77 , pp. 5529-5534
    • Ikeda, A.1    Caldwell, R.G.2    Longnecker, R.3    Ikeda, M.4
  • 39
    • 0037213918 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A interferes with global transcription factor regulation when expressed during B-lymphocyte development
    • Portis, T. & Longnecker, R. Epstein-Barr virus LMP2A interferes with global transcription factor regulation when expressed during B-lymphocyte development. J. Virol. 77, 105-114 (2003).
    • (2003) J. Virol. , vol.77 , pp. 105-114
    • Portis, T.1    Longnecker, R.2
  • 40
    • 0029558617 scopus 로고
    • The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation
    • Sato, S., Steeber, D.A. & Tedder, T.F. The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation. Proc. Natl. Acad. Sci. USA 92, 11558-11562 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11558-11562
    • Sato, S.1    Steeber, D.A.2    Tedder, T.F.3
  • 41
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi, H. et al. A Toll-like receptor recognizes bacterial DNA. Nature 408, 740-745 (2000).
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1
  • 42
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
    • Hoshino, K. et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162, 3749-3752 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 3749-3752
    • Hoshino, K.1
  • 43
    • 0035810399 scopus 로고    scopus 로고
    • Complement. First of two parts
    • Walport, M.J. Complement. First of two parts. N. Engl. J. Med. 344, 1058-1066 (2001).
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1058-1066
    • Walport, M.J.1
  • 44
    • 0035174046 scopus 로고    scopus 로고
    • Collaboration of epithelial cells with organized mucosal lymphoid tissues
    • Neutra, M.R., Mantis, N.J: & Kraehenbuhl, J.P. Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nat. Immunol. 2, 1004-1009 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 1004-1009
    • Neutra, M.R.1    Mantis, N.J.2    Kraehenbuhl, J.P.3
  • 46
    • 0033103158 scopus 로고    scopus 로고
    • Lymph node germinal centers form in the absence of follicular dendritic cell networks
    • Koni, P.A. & Flavell, R.A. Lymph node germinal centers form in the absence of follicular dendritic cell networks. J. Exp. Med. 189, 855-864 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 855-864
    • Koni, P.A.1    Flavell, R.A.2
  • 47
    • 0033920322 scopus 로고    scopus 로고
    • Development of the antibody repertoire in rabbit: Gut-associated lymphoid tissue, microbes, and selection
    • Lanning, D., Zhu, X., Zhai, S.K. & Knight, K.L. Development of the antibody repertoire in rabbit: gut-associated lymphoid tissue, microbes, and selection. Immunol. Rev. 175, 214-228 (2000).
    • (2000) Immunol. Rev. , vol.175 , pp. 214-228
    • Lanning, D.1    Zhu, X.2    Zhai, S.K.3    Knight, K.L.4
  • 48
    • 0023652339 scopus 로고
    • A hyperconversion mechanism generates the chicken light chain preimmune repertoire
    • Reynaud, C.A., Anquez, V., Grimal, H. & Weill, J.C. A hyperconversion mechanism generates the chicken light chain preimmune repertoire. Cell 48, 379-388 (1987).
    • (1987) Cell , vol.48 , pp. 379-388
    • Reynaud, C.A.1    Anquez, V.2    Grimal, H.3    Weill, J.C.4
  • 49
    • 0025970135 scopus 로고
    • Somatic generation of diversity in a mammalian primary lymphoid organ: The sheep ileal Peyer's patches
    • Reynaud, C.A., Mackay, C.R., Muller, R.G. & Weill, J.C. Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches. Cell 64, 995-1005 (1991).
    • (1991) Cell , vol.64 , pp. 995-1005
    • Reynaud, C.A.1    Mackay, C.R.2    Muller, R.G.3    Weill, J.C.4
  • 50
    • 0037378734 scopus 로고    scopus 로고
    • A new model of sheep Ig diversification: Shifting the emphasis toward combinatorial mechanisms and away from hypermutation
    • Jenne, C.N., Kennedy, L.J., McCullagh, P. & Reynolds, J.D. A new model of sheep Ig diversification: shifting the emphasis toward combinatorial mechanisms and away from hypermutation. J. Immunol. 170, 3739-3750 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 3739-3750
    • Jenne, C.N.1    Kennedy, L.J.2    McCullagh, P.3    Reynolds, J.D.4
  • 51
    • 0035970105 scopus 로고    scopus 로고
    • CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans
    • Weller, S. et al. CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans. Proc. Natl. Acad. Sci. USA 98, 1166-1170 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1166-1170
    • Weller, S.1
  • 52
    • 0031919997 scopus 로고    scopus 로고
    • The origin of Hodgkin and Reed/Sternberg cells in Hodgkin's disease
    • Kueppers, R. & Rajewsky, K. The origin of Hodgkin and Reed/Sternberg cells in Hodgkin's disease. Annu. Rev. Immunol. 16, 471-493 (1998).
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 471-493
    • Kueppers, R.1    Rajewsky, K.2
  • 53
    • 0029952779 scopus 로고    scopus 로고
    • Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells
    • Kanzler, H., Kuppers, R., Hansmann, M.L. & Rajewsky, K. Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. J. Exp. Med. 184, 1495-1505 (1996).
    • (1996) J. Exp. Med. , vol.184 , pp. 1495-1505
    • Kanzler, H.1    Kuppers, R.2    Hansmann, M.L.3    Rajewsky, K.4
  • 54
    • 0030888193 scopus 로고    scopus 로고
    • B cell development under the condition of allelic inclusion
    • Sonoda, E. et al. B cell development under the condition of allelic inclusion. Immunity 6, 225-233 (1997).
    • (1997) Immunity , vol.6 , pp. 225-233
    • Sonoda, E.1
  • 55
    • 0027485834 scopus 로고
    • Manipulation of transgenes by site-specific recombination: Use of Cre recombinase
    • Sauer, B. Manipulation of transgenes by site-specific recombination: use of Cre recombinase. Methods Enzymol. 225, 890-900 (1993).
    • (1993) Methods Enzymol. , vol.225 , pp. 890-900
    • Sauer, B.1
  • 56
    • 0029566108 scopus 로고
    • A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
    • Schwenk, F., Baron, U. & Rajewsky, K. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res. 23, 5080-5081 (1995).
    • (1995) Nucleic Acids Res. , vol.23 , pp. 5080-5081
    • Schwenk, F.1    Baron, U.2    Rajewsky, K.3
  • 57
    • 0029558338 scopus 로고
    • Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity
    • Wessels, M.R. et al. Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity. Proc. Natl. Acad. Sci. USA 92, 11490-11494 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11490-11494
    • Wessels, M.R.1
  • 58
    • 0030249394 scopus 로고    scopus 로고
    • A prematurely expressed Igκ transgene, but not VκJκ gene segment targeted into the Igκ locus, can rescue B cell development in λ5-deficient mice
    • Pelanda, R., Schaal, S., Torres, R.M. & Rajewsky, K. A prematurely expressed Igκ transgene, but not VκJκ gene segment targeted into the Igκ locus, can rescue B cell development in λ5-deficient mice. Immunity 5, 229-239 (1996).
    • (1996) Immunity , vol.5 , pp. 229-239
    • Pelanda, R.1    Schaal, S.2    Torres, R.M.3    Rajewsky, K.4
  • 59
    • 0027528956 scopus 로고
    • Epstein-Barr virus-induced genes: First lymphocyte-specific G protein-coupled peptide receptors
    • Birkenbach, M., Josefsen, K., Yalamanchili, R., Lenoir, G. & Kieff, E. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. J. Virol. 67, 2209-2220 (1993).
    • (1993) J. Virol. , vol.67 , pp. 2209-2220
    • Birkenbach, M.1    Josefsen, K.2    Yalamanchili, R.3    Lenoir, G.4    Kieff, E.5


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