-
1
-
-
0024353079
-
Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann, T.R., and R.L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
-
(1989)
Annu. Rev. Immunol
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
2
-
-
33847206969
-
IL-17 family cytokines and the expanding diversity of effector T cell lineages
-
Weaver, C.T., R.D. Hatton, P.R. Mangan, and L.E. Harrington. 2007. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25:821-852.
-
(2007)
Annu. Rev. Immunol
, vol.25
, pp. 821-852
-
-
Weaver, C.T.1
Hatton, R.D.2
Mangan, P.R.3
Harrington, L.E.4
-
3
-
-
34247523141
-
Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation
-
Kastelein, R.A., C.A. Hunter, and D.J. Cua. 2007. Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Annu. Rev. Immunol. 25:221-242.
-
(2007)
Annu. Rev. Immunol
, vol.25
, pp. 221-242
-
-
Kastelein, R.A.1
Hunter, C.A.2
Cua, D.J.3
-
4
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva, R., X.O. Yang, G. Martinez, Y. Zhang, A.D. Panopoulos, L. Ma, K. Schluns, Q. Tian, S.S. Watowich, A.M. Jetten, and C. Dong. 2007. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature. 448:480-483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
Zhang, Y.4
Panopoulos, A.D.5
Ma, L.6
Schluns, K.7
Tian, Q.8
Watowich, S.S.9
Jetten, A.M.10
Dong, C.11
-
5
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn, T., E. Bettelli, W. Gao, A. Awasthi, A. Jager, T.B. Strom, M. Oukka, and V.K. Kuchroo. 2007. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature. 448:484-487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
Awasthi, A.4
Jager, A.5
Strom, T.B.6
Oukka, M.7
Kuchroo, V.K.8
-
6
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou, L., I.I. Ivanov, R. Spolski, R. Min, K. Shenderov, T. Egawa, D.E. Levy, W.J. Leonard, and D.R. Littman. 2007. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 8:967-974.
-
(2007)
Nat. Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
Levy, D.E.7
Leonard, W.J.8
Littman, D.R.9
-
7
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi, S. 2004. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22:531-562.
-
(2004)
Annu. Rev. Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
8
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux, H., A. O'Garra, M. Bigler, M. Rouleau, S. Antonenko, J.E. de Vries, and M.G. Roncarolo. 1997. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature. 389:737-742.
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
de Vries, J.E.6
Roncarolo, M.G.7
-
9
-
-
0038631849
-
Type 1 T-regulatory cells: Their role in the control of immune responses
-
Groux, H. 2003. Type 1 T-regulatory cells: their role in the control of immune responses. Transplantation. 75:8S-12S.
-
(2003)
Transplantation
, vol.75
-
-
Groux, H.1
-
10
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli, E., Y. Carrier, W. Gao, T. Korn, T.B. Strom, M. Oukka, H.L. Weiner, and V.K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
11
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan, P.R., L.E. Harrington, D.B. O'Quinn, W.S. Helms, D.C. Bullard, C.O. Elson, R.D. Hatton, S.M. Wahl, T.R. Schoeb, and C.T. Weaver. 2006. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature. 441:231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
Schoeb, T.R.9
Weaver, C.T.10
-
12
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen, M., R.J. Hocking, C.J. Atkins, R.M. Locksley, and B. Stockinger. 2006. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 24:179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
13
-
-
36248965294
-
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology
-
McGeachy, M.J., K.S. Bak-Jensen, Y. Chen, C.M. Tato, W. Blumenschein, T. McClanahan, and D.J. Cua. 2007. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat. Immunol. 8:1390-1397.
-
(2007)
Nat. Immunol
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
Bak-Jensen, K.S.2
Chen, Y.3
Tato, C.M.4
Blumenschein, W.5
McClanahan, T.6
Cua, D.J.7
-
14
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn, R., J. Lohler, D. Rennick, K. Rajewsky, and W. Muller. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 75:263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
15
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen, D., J. Cheung, H. Scheerens, F. Poulet, T. McClanahan, B. McKenzie, M.A. Kleinschek, A. Owyang, J. Mattson, W. Blumenschein, et al. 2006. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 116:1310-1316.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
-
16
-
-
34249678457
-
T(H)1 cells control themselves by producing interleukin-10
-
O'Garra, A., and P. Vieira. 2007. T(H)1 cells control themselves by producing interleukin-10. Nat. Rev. Immunol. 7:425-428.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 425-428
-
-
O'Garra, A.1
Vieira, P.2
-
17
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer, J.S., J.S. Silver, A. Laurence, P.M. Porrett, T.H. Harris, L.A. Turka, M. Ernst, C.J. Saris, J.J. O'Shea, and C.A. Hunter. 2007. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat. Immunol. 8:1363-1371.
-
(2007)
Nat. Immunol
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
Porrett, P.M.4
Harris, T.H.5
Turka, L.A.6
Ernst, M.7
Saris, C.J.8
O'Shea, J.J.9
Hunter, C.A.10
-
18
-
-
36248970702
-
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
-
Fitzgerald, D.C., G.X. Zhang, M. El-Behi, Z. Fonseca-Kelly, H. Li, S. Yu, C.J. Saris, B. Gran, B. Ciric, and A. Rostami. 2007. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat. Immunol. 8:1372-1379.
-
(2007)
Nat. Immunol
, vol.8
, pp. 1372-1379
-
-
Fitzgerald, D.C.1
Zhang, G.X.2
El-Behi, M.3
Fonseca-Kelly, Z.4
Li, H.5
Yu, S.6
Saris, C.J.7
Gran, B.8
Ciric, B.9
Rostami, A.10
-
19
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10-producing antiinflammatory T cells
-
Awasthi, A., Y. Carrier, J.P. Peron, E. Bettelli, M. Kamanaka, R.A. Flavell, V.K. Kuchroo, M. Oukka, and H.L. Weiner. 2007. A dominant function for interleukin 27 in generating interleukin 10-producing antiinflammatory T cells. Nat. Immunol. 8:1380-1389.
-
(2007)
Nat. Immunol
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
Carrier, Y.2
Peron, J.P.3
Bettelli, E.4
Kamanaka, M.5
Flavell, R.A.6
Kuchroo, V.K.7
Oukka, M.8
Weiner, H.L.9
-
20
-
-
0348223787
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198:1875-1886.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
21
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
Mucida, D., Y. Park, G. Kim, O. Turovskaya, I. Scott, M. Kronenberg, and H. Cheroutre. 2007. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science. 317:256-260.
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
Cheroutre, H.7
-
22
-
-
34547769253
-
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
-
Benson, M.J., K. Pino-Lagos, M. Rosemblatt, and R.J. Noelle. 2007. All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J. Exp. Med. 204:1765-1774.
-
(2007)
J. Exp. Med
, vol.204
, pp. 1765-1774
-
-
Benson, M.J.1
Pino-Lagos, K.2
Rosemblatt, M.3
Noelle, R.J.4
-
23
-
-
34247271308
-
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
-
Williams, L.M., and A.Y. Rudensky. 2007. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat. Immunol. 8:277-284.
-
(2007)
Nat. Immunol
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
24
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor Foxp3
-
Fontenot, J.D., J.P. Rasmussen, L.M. Williams, J.L. Dooley, A.G. Farr, and A.Y. Rudensky. 2005. Regulatory T cell lineage specification by the forkhead transcription factor Foxp3. Immunity. 22:329-341.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
25
-
-
33846423147
-
+ regulatory T cells induces a scurfy-like disease
-
+ regulatory T cells induces a scurfy-like disease. J. Exp. Med. 204:57-63.
-
(2007)
J. Exp. Med
, vol.204
, pp. 57-63
-
-
Lahl, K.1
Loddenkemper, C.2
Drouin, C.3
Freyer, J.4
Arnason, J.5
Eberl, G.6
Hamann, A.7
Wagner, H.8
Huehn, J.9
Sparwasser, T.10
-
26
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M.E., E.W. Jeffery, K.A. Hjerrild, B. Paeper, L.B. Clark, S.A. Yasayko, J.E. Wilkinson, D. Galas, S.F. Ziegler, and F. Ramsdell. 2001. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27:68-73.
-
(2001)
Nat. Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
Wilkinson, J.E.7
Galas, D.8
Ziegler, S.F.9
Ramsdell, F.10
-
27
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C.L., Y. Chen, W.M. Blumenschein, J. Mattson, B. Basham, J.D. Sedgwick, T. McClanahan, R.A. Kastelein, and D.J. Cua. 2005. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201:233-240.
-
(2005)
J. Exp. Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
28
-
-
33750142276
-
Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
-
Veldhoen, M., R.J. Hocking, R.A. Flavell, and B. Stockinger. 2006. Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease. Nat. Immunol. 7:1151-1156.
-
(2006)
Nat. Immunol
, vol.7
, pp. 1151-1156
-
-
Veldhoen, M.1
Hocking, R.J.2
Flavell, R.A.3
Stockinger, B.4
-
29
-
-
0346962972
-
Divergent proand antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
Murphy, C.A., C.L. Langrish, Y. Chen, W. Blumenschein, T. McClanahan, R.A. Kastelein, J.D. Sedgwick, and D.J. Cua. 2003. Divergent proand antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J. Exp. Med. 198:1951-1957.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.5
Kastelein, R.A.6
Sedgwick, J.D.7
Cua, D.J.8
-
30
-
-
33750505009
-
Interleukin-23 drives innate and T cell-mediated intestinal inflammation
-
Hue, S., P. Ahern, S. Buonocore, M.C. Kullberg, D.J. Cua, B.S. McKenzie, F. Powrie, and K.J. Maloy. 2006. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J. Exp. Med. 203:2473-2483.
-
(2006)
J. Exp. Med
, vol.203
, pp. 2473-2483
-
-
Hue, S.1
Ahern, P.2
Buonocore, S.3
Kullberg, M.C.4
Cua, D.J.5
McKenzie, B.S.6
Powrie, F.7
Maloy, K.J.8
-
31
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr, R.H., K.D. Taylor, S.R. Brant, J.D. Rioux, M.S. Silverberg, M.J. Daly, A.H. Steinhart, C. Abraham, M. Regueiro, A. Griffiths, et al. 2006. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 314:1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
-
32
-
-
33645521806
-
Antibody-independent, interleukin-17A- mediated, cross-serotype immunity to pneumococci in mice immunized intranasally with the cell wall polysaccharide
-
Malley, R., A. Srivastava, M. Lipsitch, C.M. Thompson, C. Watkins, A. Tzianabos, and P.W. Anderson. 2006. Antibody-independent, interleukin-17A- mediated, cross-serotype immunity to pneumococci in mice immunized intranasally with the cell wall polysaccharide. Infect. Immun. 74:2187-2195.
-
(2006)
Infect. Immun
, vol.74
, pp. 2187-2195
-
-
Malley, R.1
Srivastava, A.2
Lipsitch, M.3
Thompson, C.M.4
Watkins, C.5
Tzianabos, A.6
Anderson, P.W.7
-
33
-
-
25144515561
-
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae
-
Happel, K.I., P.J. Dubin, M. Zheng, N. Ghilardi, C. Lockhart, L.J. Quinton, A.R. Odden, J.E. Shellito, G.J. Bagby, S. Nelson, and J.K. Kolls. 2005. Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. J. Exp. Med. 202:761-769.
-
(2005)
J. Exp. Med
, vol.202
, pp. 761-769
-
-
Happel, K.I.1
Dubin, P.J.2
Zheng, M.3
Ghilardi, N.4
Lockhart, C.5
Quinton, L.J.6
Odden, A.R.7
Shellito, J.E.8
Bagby, G.J.9
Nelson, S.10
Kolls, J.K.11
-
34
-
-
34248562792
-
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
-
Khader, S.A., G.K. Bell, J.E. Pearl, J.J. Fountain, J. Rangel-Moreno, G.E. Cilley, F. Shen, S.M. Eaton, S.L. Gaffen, S.L. Swain, et al. 2007. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat. Immunol. 8:369-377.
-
(2007)
Nat. Immunol
, vol.8
, pp. 369-377
-
-
Khader, S.A.1
Bell, G.K.2
Pearl, J.E.3
Fountain, J.J.4
Rangel-Moreno, J.5
Cilley, G.E.6
Shen, F.7
Eaton, S.M.8
Gaffen, S.L.9
Swain, S.L.10
-
35
-
-
35348915412
-
IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance
-
Zelante, T., A. De Luca, P. Bonifazi, C. Montagnoli, S. Bozza, S. Moretti, M.L. Belladonna, C. Vacca, C. Conte, P. Mosci, et al. 2007. IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur. J. Immunol. 37:2695-2706.
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 2695-2706
-
-
Zelante, T.1
De Luca, A.2
Bonifazi, P.3
Montagnoli, C.4
Bozza, S.5
Moretti, S.6
Belladonna, M.L.7
Vacca, C.8
Conte, C.9
Mosci, P.10
-
36
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez, E.V., L. Rivino, J. Geginat, D. Jarrossay, M. Gattorno, A. Lanzavecchia, F. Sallusto, and G. Napolitani. 2007. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol. 8:639-646.
-
(2007)
Nat. Immunol
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
Jarrossay, D.4
Gattorno, M.5
Lanzavecchia, A.6
Sallusto, F.7
Napolitani, G.8
-
37
-
-
34748873441
-
Regulatory T cells and infection: A dangerous necessity
-
Belkaid, Y. 2007. Regulatory T cells and infection: a dangerous necessity. Nat. Rev. Immunol. 7:875-888.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 875-888
-
-
Belkaid, Y.1
-
38
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid, Y., C.A. Piccirillo, S. Mendez, E.M. Shevach, and D.L. Sacks. 2002. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature. 420:502-507.
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
39
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, I.I., B.S. McKenzie, L. Zhou, C.E. Tadokoro, A. Lepelley, J.J. Lafaille, D.J. Cua, and D.R. Littman. 2006. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell. 126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
40
-
-
1042291142
-
General method for the modification of different BAC types and the rapid generation of BAC transgenic mice
-
Sparwasser, T., S. Gong, J.Y. Li, and G. Eberl. 2004. General method for the modification of different BAC types and the rapid generation of BAC transgenic mice. Genesis. 38:39-50.
-
(2004)
Genesis
, vol.38
, pp. 39-50
-
-
Sparwasser, T.1
Gong, S.2
Li, J.Y.3
Eberl, G.4
-
41
-
-
0346496018
-
An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells
-
Eberl, G., S. Marmon, M.J. Sunshine, P.D. Rennert, Y. Choi, and D.R. Littman. 2004. An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5:64-73.
-
(2004)
Nat. Immunol
, vol.5
, pp. 64-73
-
-
Eberl, G.1
Marmon, S.2
Sunshine, M.J.3
Rennert, P.D.4
Choi, Y.5
Littman, D.R.6
-
42
-
-
3042720708
-
Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells
-
Eberl, G., and D.R. Littman. 2004. Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells. Science. 305:248-251.
-
(2004)
Science
, vol.305
, pp. 248-251
-
-
Eberl, G.1
Littman, D.R.2
-
43
-
-
0037370324
-
Inducible costimulator is essential for collagen-induced arthritis
-
Nurieva, R.I., P. Treuting, J. Duong, R.A. Flavell, and C. Dong. 2003. Inducible costimulator is essential for collagen-induced arthritis. J. Clin. Invest. 111:701-706.
-
(2003)
J. Clin. Invest
, vol.111
, pp. 701-706
-
-
Nurieva, R.I.1
Treuting, P.2
Duong, J.3
Flavell, R.A.4
Dong, C.5
-
44
-
-
36549019912
-
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
-
Hirota, K., H. Yoshitomi, M. Hashimoto, S. Maeda, S. Teradaira, N. Sugimoto, T. Yamaguchi, T. Nomura, H. Ito, T. Nakamura, et al. 2007. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J. Exp. Med. 204:2803-2812.
-
(2007)
J. Exp. Med
, vol.204
, pp. 2803-2812
-
-
Hirota, K.1
Yoshitomi, H.2
Hashimoto, M.3
Maeda, S.4
Teradaira, S.5
Sugimoto, N.6
Yamaguchi, T.7
Nomura, T.8
Ito, H.9
Nakamura, T.10
-
45
-
-
1942501856
-
Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways
-
Prause, O., S. Bozinovski, G.P. Anderson, and A. Linden. 2004. Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways. Thorax. 59:313-317.
-
(2004)
Thorax
, vol.59
, pp. 313-317
-
-
Prause, O.1
Bozinovski, S.2
Anderson, G.P.3
Linden, A.4
-
46
-
-
26844554064
-
Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis
-
Koenders, M.I., J.K. Kolls, B. Oppers-Walgreen, L. van den Bersselaar, L.A. Joosten, J.R. Schurr, P. Schwarzenberger, W.B. van den Berg, and E. Lubberts. 2005. Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis. Arthritis Rheum. 52:3239-3247.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3239-3247
-
-
Koenders, M.I.1
Kolls, J.K.2
Oppers-Walgreen, B.3
van den Bersselaar, L.4
Joosten, L.A.5
Schurr, J.R.6
Schwarzenberger, P.7
van den Berg, W.B.8
Lubberts, E.9
-
47
-
-
0031036347
-
A new class of membrane-bound chemokine with a CX3C motif
-
Bazan, J.F., K.B. Bacon, G. Hardiman, W. Wang, K. Soo, D. Rossi, D.R. Greaves, A. Zlotnik, and T.J. Schall. 1997. A new class of membrane-bound chemokine with a CX3C motif. Nature. 385:640-644.
-
(1997)
Nature
, vol.385
, pp. 640-644
-
-
Bazan, J.F.1
Bacon, K.B.2
Hardiman, G.3
Wang, W.4
Soo, K.5
Rossi, D.6
Greaves, D.R.7
Zlotnik, A.8
Schall, T.J.9
-
48
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato, F., L. Cosmi, V. Santarlasci, L. Maggi, F. Liotta, B. Mazzinghi, E. Parente, L. Fili, S. Ferri, F. Frosali, et al. 2007. Phenotypic and functional features of human Th17 cells. J. Exp. Med. 204:1849-1861.
-
(2007)
J. Exp. Med
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
Parente, E.7
Fili, L.8
Ferri, S.9
Frosali, F.10
-
49
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson, N.J., K. Boniface, J.R. Chan, B.S. McKenzie, W.M. Blumenschein, J.D. Mattson, B. Basham, K. Smith, T. Chen, F. Morel, et al. 2007. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat. Immunol. 8:950-957.
-
(2007)
Nat. Immunol
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
Boniface, K.2
Chan, J.R.3
McKenzie, B.S.4
Blumenschein, W.M.5
Mattson, J.D.6
Basham, B.7
Smith, K.8
Chen, T.9
Morel, F.10
-
50
-
-
0035107851
-
CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses
-
Varona, R., R. Villares, L. Carramolino, I. Goya, A. Zaballos, J. Gutierrez, M. Torres, A.C. Martinez, and G. Marquez. 2001. CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses. J. Clin. Invest. 107:37-45.
-
(2001)
J. Clin. Invest
, vol.107
, pp. 37-45
-
-
Varona, R.1
Villares, R.2
Carramolino, L.3
Goya, I.4
Zaballos, A.5
Gutierrez, J.6
Torres, M.7
Martinez, A.C.8
Marquez, G.9
-
51
-
-
33746860835
-
An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locus
-
Brockschnieder, D., Y. Pechmann, E. Sonnenberg-Riethmacher, and D. Riethmacher. 2006. An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locus. Genesis. 44:322-327.
-
(2006)
Genesis
, vol.44
, pp. 322-327
-
-
Brockschnieder, D.1
Pechmann, Y.2
Sonnenberg-Riethmacher, E.3
Riethmacher, D.4
-
52
-
-
0027340690
-
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias
-
Moser, A.R., E.M. Mattes, W.F. Dove, M.J. Lindstrom, J.D. Haag, and M.N. Gould. 1993. ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias. Proc. Natl. Acad. Sci. USA. 90:8977-8981.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8977-8981
-
-
Moser, A.R.1
Mattes, E.M.2
Dove, W.F.3
Lindstrom, M.J.4
Haag, J.D.5
Gould, M.N.6
-
53
-
-
34249806717
-
Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment
-
Kryczek, I., S. Wei, L. Zou, S. Altuwaijri, W. Szeliga, J. Kolls, A. Chang, and W. Zou. 2007. Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment. J. Immunol. 178:6730-6733.
-
(2007)
J. Immunol
, vol.178
, pp. 6730-6733
-
-
Kryczek, I.1
Wei, S.2
Zou, L.3
Altuwaijri, S.4
Szeliga, W.5
Kolls, J.6
Chang, A.7
Zou, W.8
-
54
-
-
15944425718
-
CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset
-
Kleinewietfeld, M., F. Puentes, G. Borsellino, L. Battistini, O. Rotzschke, and K. Falk. 2005. CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset. Blood. 105:2877-2886.
-
(2005)
Blood
, vol.105
, pp. 2877-2886
-
-
Kleinewietfeld, M.1
Puentes, F.2
Borsellino, G.3
Battistini, L.4
Rotzschke, O.5
Falk, K.6
-
55
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H., Z. Li, X.O. Yang, S.H. Chang, R. Nurieva, Y.H. Wang, Y. Wang, L. Hood, Z. Zhu, Q. Tian, and C. Dong. 2005. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6:1133-1141.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
56
-
-
3242741987
-
ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: Increased ICOS expression enhances the effector function of both Th1 and Th2 cells
-
Wassink, L., P.L. Vieira, H.H. Smits, G.A. Kingsbury, A.J. Coyle, M.L. Kapsenberg, and E.A. Wierenga. 2004. ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells. J. Immunol. 173:1779-1786.
-
(2004)
J. Immunol
, vol.173
, pp. 1779-1786
-
-
Wassink, L.1
Vieira, P.L.2
Smits, H.H.3
Kingsbury, G.A.4
Coyle, A.J.5
Kapsenberg, M.L.6
Wierenga, E.A.7
-
57
-
-
33746534417
-
IL-23 promotes tumour incidence and growth
-
Langowski, J.L., X. Zhang, L. Wu, J.D. Mattson, T. Chen, K. Smith, B. Basham, T. McClanahan, R.A. Kastelein, and M. Oft. 2006. IL-23 promotes tumour incidence and growth. Nature. 442:461-465.
-
(2006)
Nature
, vol.442
, pp. 461-465
-
-
Langowski, J.L.1
Zhang, X.2
Wu, L.3
Mattson, J.D.4
Chen, T.5
Smith, K.6
Basham, B.7
McClanahan, T.8
Kastelein, R.A.9
Oft, M.10
-
58
-
-
38449093216
-
Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells
-
Roark, C.L., J.D. French, M.A. Taylor, A.M. Bendele, W.K. Born, and R.L. O'Brien. 2007. Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells. J. Immunol. 179:5576-5583.
-
(2007)
J. Immunol
, vol.179
, pp. 5576-5583
-
-
Roark, C.L.1
French, J.D.2
Taylor, M.A.3
Bendele, A.M.4
Born, W.K.5
O'Brien, R.L.6
-
59
-
-
33749138039
-
IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection
-
Lockhart, E., A.M. Green, and J.L. Flynn. 2006. IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J. Immunol. 177:4662-4669.
-
(2006)
J. Immunol
, vol.177
, pp. 4662-4669
-
-
Lockhart, E.1
Green, A.M.2
Flynn, J.L.3
-
60
-
-
33947195292
-
IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection
-
Umemura, M., A. Yahagi, S. Hamada, M.D. Begum, H. Watanabe, K. Kawakami, T. Suda, K. Sudo, S. Nakae, Y. Iwakura, and G. Matsuzaki. 2007. IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection. J. Immunol. 178:3786-3796.
-
(2007)
J. Immunol
, vol.178
, pp. 3786-3796
-
-
Umemura, M.1
Yahagi, A.2
Hamada, S.3
Begum, M.D.4
Watanabe, H.5
Kawakami, K.6
Suda, T.7
Sudo, K.8
Nakae, S.9
Iwakura, Y.10
Matsuzaki, G.11
-
61
-
-
33947677787
-
Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production
-
Shibata, K., H. Yamada, H. Hara, K. Kishihara, and Y. Yoshikai. 2007. Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. J. Immunol. 178:4466-4472.
-
(2007)
J. Immunol
, vol.178
, pp. 4466-4472
-
-
Shibata, K.1
Yamada, H.2
Hara, H.3
Kishihara, K.4
Yoshikai, Y.5
-
63
-
-
0035252656
-
Hijacking and exploitation of IL-10 by intracellular pathogens
-
Redpath, S., P. Ghazal, and N.R. Gascoigne. 2001. Hijacking and exploitation of IL-10 by intracellular pathogens. Trends Microbiol. 9:86-92.
-
(2001)
Trends Microbiol
, vol.9
, pp. 86-92
-
-
Redpath, S.1
Ghazal, P.2
Gascoigne, N.R.3
|