-
1
-
-
0024408824
-
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
-
Fiorentino, D.F., Bond, M.W. & Mosmann, T.R. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 170, 2081-2095 (1989).
-
(1989)
J. Exp. Med
, vol.170
, pp. 2081-2095
-
-
Fiorentino, D.F.1
Bond, M.W.2
Mosmann, T.R.3
-
2
-
-
0025335354
-
Homology of Cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI
-
Moore, K.W. et al. Homology of Cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science 248, 1230-1234 (1990).
-
(1990)
Science
, vol.248
, pp. 1230-1234
-
-
Moore, K.W.1
-
3
-
-
0035062021
-
Interleukin-10 and the interleukin-10 receptor
-
Moore, K.W., de Waal Malefyt, R., Coffman R. L. & O'Garra, A. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19, 683-765 (2001).
-
(2001)
Annu. Rev. Immunol
, vol.19
, pp. 683-765
-
-
Moore, K.W.1
de Waal Malefyt, R.2
Coffman, R.L.3
O'Garra, A.4
-
4
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn, R., Lohler, J, Rennick, D., Rajewsky, K. & Muller, W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75, 263-274 (1993).
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
5
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen, D. et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 216 1310-1316 (2006).
-
(2006)
J. Clin. Invest
, vol.216
, pp. 1310-1316
-
-
Yen, D.1
-
6
-
-
0041652405
-
Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis
-
Grunig, G. et al. Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis. J. Exp. Med. 185, 1089-1099 (1997).
-
(1997)
J. Exp. Med
, vol.185
, pp. 1089-1099
-
-
Grunig, G.1
-
7
-
-
0029959459
-
+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α
-
106
-
+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α. J. Immunol. 157, 798-805 (106).
-
J. Immunol
, vol.157
, pp. 798-805
-
-
Gazzinelli, R.T.1
-
8
-
-
0031112271
-
IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi
-
Hunter, C.A. et al. IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi. J. Immunol. 158, 3311-3316 (1997).
-
(1997)
J. Immunol
, vol.158
, pp. 3311-3316
-
-
Hunter, C.A.1
-
9
-
-
0030704726
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389, 737-742 (1997).
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
-
11
-
-
1042269477
-
+ regulatory T cells
-
+ regulatory T cells. Int. Immunol. 16, 249-256 (2004).
-
(2004)
Int. Immunol
, vol.16
, pp. 249-256
-
-
Zhang, X.1
-
12
-
-
0034613767
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192, 1213-1222 (2000).
-
(2000)
J. Exp. Med
, vol.192
, pp. 1213-1222
-
-
Jonuleit, H.1
Schmitt, E.2
Schuler, G.3
Knop, J.4
Enk, A.H.5
-
13
-
-
2442450433
-
+ regulatory T cells
-
+ regulatory T cells. J. Immunnol. 172, 5986-5993 (2004).
-
(2004)
J. Immunnol
, vol.172
, pp. 5986-5993
-
-
Vieira, P.L.1
-
14
-
-
0027204621
-
Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
-
Del Prete, G. et al. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J. Immunol. 150, 353-360 (1993).
-
(1993)
J. Immunol
, vol.150
, pp. 353-360
-
-
Del Prete, G.1
-
15
-
-
0029984051
-
Interleukin-12 primes human CD4 and CD8 Tcell clones for high production of both interferon-and interleukin-10
-
Gerosa, F. et al. Interleukin-12 primes human CD4 and CD8 Tcell clones for high production of both interferon-and interleukin-10. J. Exp. Med. 183, 2559-2569 (1996).
-
(1996)
J. Exp. Med
, vol.183
, pp. 2559-2569
-
-
Gerosa, F.1
-
16
-
-
34249678457
-
-
H1 cells control themselves by producing interleukin-10. Nat. Rev. Immunol. 7, 425-428 (2007).
-
H1 cells control themselves by producing interleukin-10. Nat. Rev. Immunol. 7, 425-428 (2007).
-
-
-
-
17
-
-
33847165817
-
Interleukin-10 production by effector T cells: Th1 cells show self control
-
Trinchieri, G. Interleukin-10 production by effector T cells: Th1 cells show self control. J. Exp. Med. 204, 239-243 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 239-243
-
-
Trinchieri, G.1
-
18
-
-
0032872122
-
+ T cell clones producing both interferon-γ and interleukin-10 predominate in bronchoalveolar lavages of active pulmonary tuberculosis patients
-
+ T cell clones producing both interferon-γ and interleukin-10 predominate in bronchoalveolar lavages of active pulmonary tuberculosis patients. Clin. Immunol. 92, 224-234 (1999).
-
(1999)
Clin. Immunol
, vol.92
, pp. 224-234
-
-
Gerosa, F.1
-
19
-
-
0032520148
-
Identification of a T cell subset capable of bath IFN-γ and IL-10 secretion in patients with chronic Borrelia burgdorferi infection
-
Pohl-Koppe, A., Balashov, K.E., Steere, A.C., Logigian, E.L. & Hafler, D.A. Identification of a T cell subset capable of bath IFN-γ and IL-10 secretion in patients with chronic Borrelia burgdorferi infection. J. Immunol. 160, 1864-1810 (1998).
-
(1998)
J. Immunol
, vol.160
, pp. 1864-1810
-
-
Pohl-Koppe, A.1
Balashov, K.E.2
Steere, A.C.3
Logigian, E.L.4
Hafler, D.A.5
-
20
-
-
33847163271
-
-
+CD25-Foxp3-Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J. Exp. Med. 204, 285-297 (2007).
-
+CD25-Foxp3-Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J. Exp. Med. 204, 285-297 (2007).
-
-
-
-
21
-
-
33847144180
-
+Foxp3- Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
-
+Foxp3- Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J. Exp. Med. 204, 273-283 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 273-283
-
-
Jaskovic, D.1
-
23
-
-
0034687402
-
Development of Th1 -type immune responses requires the type 1 cytokine receptor TCCR
-
Chen, Q. et al. Development of Th1 -type immune responses requires the type 1 cytokine receptor TCCR. Nature 407, 916-920 (2000).
-
(2000)
Nature
, vol.407
, pp. 916-920
-
-
Chen, Q.1
-
24
-
-
33747588291
-
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
-
Batten, M. et al. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat. Immunol. 7, 929-936 (2006).
-
(2006)
Nat. Immunol
, vol.7
, pp. 929-936
-
-
Batten, M.1
-
25
-
-
34250005444
-
H17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited.by IL-27/STAT1
-
H17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited.by IL-27/STAT1. Nat. Med. 13, 711-718 (2007).
-
(2007)
Nat. Med
, vol.13
, pp. 711-718
-
-
Amadi-Obi, A.1
-
26
-
-
34247523141
-
Discovery and biology of IL-23 and IL-27; related but functionally distinct regulators of inflammation
-
Kastelein, R.A., Hunter, C.A. & Cua, D.J. Discovery and biology of IL-23 and IL-27; related but functionally distinct regulators of inflammation. Annu. Rev. Immunol. 25, 221-242 (2007).
-
(2007)
Annu. Rev. Immunol
, vol.25
, pp. 221-242
-
-
Kastelein, R.A.1
Hunter, C.A.2
Cua, D.J.3
-
27
-
-
0345570521
-
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
-
Villarino, A. et al. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 19, 645-655 (2003).
-
(2003)
Immunity
, vol.19
, pp. 645-655
-
-
Villarino, A.1
-
28
-
-
33747593830
-
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
-
Stumhofer, J.S. et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat. Immunol. 7, 937-945 (2006).
-
(2006)
Nat. Immunol
, vol.7
, pp. 937-945
-
-
Stumhofer, J.S.1
-
29
-
-
20444375878
-
Positive and negative, regulation of the IL-27 receptor during lymphoid cel activation
-
Villarino, A.V. et al. Positive and negative, regulation of the IL-27 receptor during lymphoid cel activation. J. Immunol. 174 7684-7691 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 7684-7691
-
-
Villarino, A.V.1
-
30
-
-
0348223787
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198, 1875-1886 (2003).
-
(2003)
J. Exp. Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
-
32
-
-
33646577466
-
H17 and regulatory T cells
-
H17 and regulatory T cells. Nature 441, 235-238 (2006).
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
-
33
-
-
34447567140
-
IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1
-
Neufert, C. et al. IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1. Eur. J. Immunol. 37, 1809-1816. (2007).
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 1809-1816
-
-
Neufert, C.1
-
34
-
-
34547232503
-
H17 cells
-
H17 cells. Nature 448, 484-487 (2007).
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
-
35
-
-
20944435271
-
Stat3 is required for ALK-Mediated lymphomagenesis and provides a possible therapeutic target
-
Chiarle, R. et al. Stat3 is required for ALK-Mediated lymphomagenesis and provides a possible therapeutic target. Nat. Med. 11, 623-629 (2005).
-
(2005)
Nat. Med
, vol.11
, pp. 623-629
-
-
Chiarle, R.1
-
36
-
-
0037018104
-
+ T cells; is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
+ T cells; is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195, 603-616 (2002).
-
(2002)
J. Exp. Med
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
-
37
-
-
10744221849
-
WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production
-
Hamano, S. et al. WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production. Immunity 19, 657-667 (2003).
-
(2003)
Immunity
, vol.19
, pp. 657-667
-
-
Hamano, S.1
-
38
-
-
30344488706
-
Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to Leishmenia donovani infection but develop severe liver immunopathology
-
Rosas, L.E. et al. Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to Leishmenia donovani infection but develop severe liver immunopathology. Am. J. Pathol. 168, 158-169 (2006).
-
(2006)
Am. J. Pathol
, vol.168
, pp. 158-169
-
-
Rosas, L.E.1
-
39
-
-
22144487678
-
A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis
-
Wilson, E.H., Wille-Reece, U., Dzierszinski, F. & Hunter, C.A. A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis. J. Neuroimmunol. 165, 63-44 (2005).
-
(2005)
J. Neuroimmunol
, vol.165
, pp. 63-44
-
-
Wilson, E.H.1
Wille-Reece, U.2
Dzierszinski, F.3
Hunter, C.A.4
-
40
-
-
21844444831
-
New IL-12-fimily members: IL-23 and IL-27, cytokines with divergent functions
-
Hunter, C.A. New IL-12-fimily members: IL-23 and IL-27, cytokines with divergent functions. Nat. Rev. Immunol. 5, 521-531 (2005).
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 521-531
-
-
Hunter, C.A.1
-
41
-
-
0034651850
-
A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages
-
Brightbill, H.D., Plevy, S.E., Modlin, R.L. & Smale, S.T. A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages. J. Immunol. 164, 1940-1951 (2000),
-
(2000)
J. Immunol
, vol.164
, pp. 1940-1951
-
-
Brightbill, H.D.1
Plevy, S.E.2
Modlin, R.L.3
Smale, S.T.4
-
42
-
-
33744783446
-
Lipopolysaccharide-induced transcriptional activation of interleukin-10 is mediated by MAPK- and NF-κB-induced CCAAT/enhancer-binding protein δ in mouse macrophages
-
Liu, Y.W., Chen, C.C., Tseng, H.P. & Chang, W.C. Lipopolysaccharide-induced transcriptional activation of interleukin-10 is mediated by MAPK- and NF-κB-induced CCAAT/enhancer-binding protein δ in mouse macrophages. Cell. Signal. 18, 1492-1500 (2006).
-
(2006)
Cell. Signal
, vol.18
, pp. 1492-1500
-
-
Liu, Y.W.1
Chen, C.C.2
Tseng, H.P.3
Chang, W.C.4
-
43
-
-
21244502077
-
ERK activation following macrophage FcγR ligation leads to chromatin modifications at the IL-10 locus
-
Lucas, M., Zhang, X., Prasanna, V. & Mosser, D.M. ERK activation following macrophage FcγR ligation leads to chromatin modifications at the IL-10 locus. J. Immunol. 175, 469-477 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 469-477
-
-
Lucas, M.1
Zhang, X.2
Prasanna, V.3
Mosser, D.M.4
-
45
-
-
0344304399
-
-
+ T cells through Stat1-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. USA 100, 15047-15052 (2003).
-
+ T cells through Stat1-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. USA 100, 15047-15052 (2003).
-
-
-
-
46
-
-
0038544646
-
IFN-α induces the human IL-10 gene by recruiting bath IFN regulatory factor 1 and Stat3
-
Ziegler-Heitbrock, L. et al. IFN-α induces the human IL-10 gene by recruiting bath IFN regulatory factor 1 and Stat3. J. Immunol. 171, 285-290 (2003).
-
(2003)
J. Immunol
, vol.171
, pp. 285-290
-
-
Ziegler-Heitbrock, L.1
-
47
-
-
0027972046
-
An interleukin-4-induced transcription factor: IL,4
-
Hou, J. et al. An interleukin-4-induced transcription factor: IL,4. Stat. Sci. 265, 1701-1706 (1994).
-
(1994)
Stat. Sci
, vol.265
, pp. 1701-1706
-
-
Hou, J.1
-
48
-
-
0028943484
-
-
Jacobson, N.G. et al. Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stal:4. J. Exp. Med. 181 1755-1762 (1995).
-
Jacobson, N.G. et al. Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stal:4. J. Exp. Med. 181 1755-1762 (1995).
-
-
-
-
49
-
-
33744479688
-
Selective regulatory function of Socs3 in the formation of IL-17- secreting T cells
-
Chen, Z. et al. Selective regulatory function of Socs3 in the formation of IL-17- secreting T cells. Proc. Natl. Acad. Sci. USA 103, 8137-8142 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8137-8142
-
-
Chen, Z.1
-
50
-
-
34247122412
-
Stat3 and Stat4 direct develepment of IL-17-secreting Th cells
-
Mathur, A.N. et al. Stat3 and Stat4 direct develepment of IL-17-secreting Th cells. J. Immunol. 178, 4901-4907 (2007).
-
(2007)
J. Immunol
, vol.178
, pp. 4901-4907
-
-
Mathur, A.N.1
-
51
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-βl gene results in multifocal inflammatory disease
-
Shull, M.M. et al. Targeted disruption of the mouse transforming growth factor-βl gene results in multifocal inflammatory disease. Nature 359, 693-699 (1992).
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
-
52
-
-
0023273817
-
Inhibition of cytokine production by cyclosporin A and transforming growth factor β
-
Espevik, T. et al. Inhibition of cytokine production by cyclosporin A and transforming growth factor β. J. Exp. Med. 166, 571-576 (1987).
-
(1987)
J. Exp. Med
, vol.166
, pp. 571-576
-
-
Espevik, T.1
-
53
-
-
0025741792
-
Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor β (TGF-β)
-
Silva, J.S., Twardzik, D.R. & Reed, S-G. Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor β (TGF-β). J. Exp. Med. 174, 539-545 (1991).
-
(1991)
J. Exp. Med
, vol.174
, pp. 539-545
-
-
Silva, J.S.1
Twardzik, D.R.2
Reed, S.-G.3
-
54
-
-
0028987734
-
-
Hunter, C.A., Bermudez, L., Beernink, H., Waegell, W. &Remington J.S. Transforming growth factor-β inhibits interlukin-12-induced production of interferon-γ by natural killer cells: A role for transforming growth factor-β in the regulation of T cell-independent pesistance to Toxoplasma-gondii. Eur. J. Immunol. 25, 994-1-1000 (1995).
-
Hunter, C.A., Bermudez, L., Beernink, H., Waegell, W. &Remington J.S. Transforming growth factor-β inhibits interlukin-12-induced production of interferon-γ by natural killer cells: A role for transforming growth factor-β in the regulation of T cell-independent pesistance to Toxoplasma-gondii. Eur. J. Immunol. 25, 994-1-1000 (1995).
-
-
-
-
55
-
-
0024353079
-
-
Mosmann, T.R. & Coffman, R.L. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7, 145-178 (1989).
-
Mosmann, T.R. & Coffman, R.L. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7, 145-178 (1989).
-
-
-
-
56
-
-
0029144414
-
High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane
-
Cohen, S.B. et al. High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane. Arthritis Rheum. 38, 946-952 (1995).
-
(1995)
Arthritis Rheum
, vol.38
, pp. 946-952
-
-
Cohen, S.B.1
-
57
-
-
0036338213
-
STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation
-
Lee, C.K. et al. STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation. Immunity 17, 63-72 (2002).
-
(2002)
Immunity
, vol.17
, pp. 63-72
-
-
Lee, C.K.1
-
58
-
-
0020570088
-
Western blot analysis of the antigens of Taxoplasma gondii recognized by human IgM and IgG antibodies
-
Sharma, S.D., Mullenax, J., Araujo, F.G., Erlich, H.A. & Remington, J.S. Western blot analysis of the antigens of Taxoplasma gondii recognized by human IgM and IgG antibodies. J. Immunol. 131, 977-983 (1983).
-
(1983)
J. Immunol
, vol.131
, pp. 977-983
-
-
Sharma, S.D.1
Mullenax, J.2
Araujo, F.G.3
Erlich, H.A.4
Remington, J.S.5
|