-
2
-
-
0035920510
-
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
-
Bensinger SJ, Bandeira A, Jordan MS, Caton AJ, Laufer TM. Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells. J Exp Med 2001 194 : 427 438.
-
(2001)
J Exp Med
, vol.194
, pp. 427-438
-
-
Bensinger, S.J.1
Bandeira, A.2
Jordan, M.S.3
Caton, A.J.4
Laufer, T.M.5
-
3
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan MS, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001 2 : 301 306.
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
4
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen W, et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003 198 : 1875 1886.
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
-
5
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 441 : 235 238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
-
6
-
-
2142645808
-
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
-
Fantini MC, Becker C, Monteleone G, Pallone F, Galle PR, Neurath MF. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J Immunol 2004 172 : 5149 5153.
-
(2004)
J Immunol
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
Becker, C.2
Monteleone, G.3
Pallone, F.4
Galle, P.R.5
Neurath, M.F.6
-
7
-
-
27944455288
-
Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen
-
Knoechel B, Lohr J, Kahn E, Bluestone JA, Abbas AK. Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J Exp Med 2005 202 : 1375 1386.
-
(2005)
J Exp Med
, vol.202
, pp. 1375-1386
-
-
Knoechel, B.1
Lohr, J.2
Kahn, E.3
Bluestone, J.A.4
Abbas, A.K.5
-
8
-
-
46749126890
-
Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation
-
Curotto de Lafaille MA, Kutchukhidze N, Shen S, Ding Y, Yee H, Lafaille JJ. Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation. Immunity 2008 29 : 114 126.
-
(2008)
Immunity
, vol.29
, pp. 114-126
-
-
Curotto De Lafaille, M.A.1
Kutchukhidze, N.2
Shen, S.3
Ding, Y.4
Yee, H.5
Lafaille, J.J.6
-
9
-
-
39549099367
-
Dendritic cells are specialized accessory cells along with TGF- for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3 precursors
-
Yamazaki S, Bonito AJ, Spisek R, Dhodapkar M, Inaba K, Steinman RM. Dendritic cells are specialized accessory cells along with TGF- for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3 precursors. Blood 2007 110 : 4293 4302.
-
(2007)
Blood
, vol.110
, pp. 4293-4302
-
-
Yamazaki, S.1
Bonito, A.J.2
Spisek, R.3
Dhodapkar, M.4
Inaba, K.5
Steinman, R.M.6
-
10
-
-
34547769253
-
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
-
Benson MJ, Pino-Lagos K, Rosemblatt M, Noelle RJ. All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med 2007 204 : 1765 1774.
-
(2007)
J Exp Med
, vol.204
, pp. 1765-1774
-
-
Benson, M.J.1
Pino-Lagos, K.2
Rosemblatt, M.3
Noelle, R.J.4
-
11
-
-
48249147441
-
Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells
-
Wang L, Pino-Lagos K, de Vries VC, Guleria I, Sayegh MH, Noelle RJ. Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells. Proc Natl Acad Sci USA 2008 105 : 9331 9336.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9331-9336
-
-
Wang, L.1
Pino-Lagos, K.2
De Vries, V.C.3
Guleria, I.4
Sayegh, M.H.5
Noelle, R.J.6
-
12
-
-
12344307563
-
Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus
-
Liang S, Alard P, Zhao Y, Parnell S, Clark SL, Kosiewicz MM. Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus. J Exp Med 2005 201 : 127 137.
-
(2005)
J Exp Med
, vol.201
, pp. 127-137
-
-
Liang, S.1
Alard, P.2
Zhao, Y.3
Parnell, S.4
Clark, S.L.5
Kosiewicz, M.M.6
-
13
-
-
33644835247
-
TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells
-
Zheng SG, Wang JH, Stohl W, Kim KS, Gray JD, Horwitz DA. TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells. J Immunol 2006 176 : 3321 3329.
-
(2006)
J Immunol
, vol.176
, pp. 3321-3329
-
-
Zheng, S.G.1
Wang, J.H.2
Stohl, W.3
Kim, K.S.4
Gray, J.D.5
Horwitz, D.A.6
-
14
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M, Bluestone JA, Barriot S, Megret J, Bach JF, Chatenoud L. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 2003 9 : 1202 1208.
-
(2003)
Nat Med
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Barriot, S.3
Megret, J.4
Bach, J.F.5
Chatenoud, L.6
-
15
-
-
3242677686
-
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
-
Latchman YE, et al. PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proc Natl Acad Sci USA 2004 101 : 10691 10696.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10691-10696
-
-
Latchman, Y.E.1
-
16
-
-
15544369658
-
Host-bacterial mutualism in the human intestine
-
Backhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. Host-bacterial mutualism in the human intestine. Science 2005 307 : 1915 1920.
-
(2005)
Science
, vol.307
, pp. 1915-1920
-
-
Backhed, F.1
Ley, R.E.2
Sonnenburg, J.L.3
Peterson, D.A.4
Gordon, J.I.5
-
17
-
-
33845428754
-
Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii
-
Heimesaat MM, et al. Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii. J Immunol 2006 177 : 8785 8795.
-
(2006)
J Immunol
, vol.177
, pp. 8785-8795
-
-
Heimesaat, M.M.1
-
18
-
-
0035871705
-
Unique functions of CD11b+, CD8 alpha+, and double-negative Peyer's patch dendritic cells
-
Iwasaki A, Kelsall BL. Unique functions of CD11b+, CD8 alpha+, and double-negative Peyer's patch dendritic cells. J Immunol 2001 166 : 4884 4890.
-
(2001)
J Immunol
, vol.166
, pp. 4884-4890
-
-
Iwasaki, A.1
Kelsall, B.L.2
-
19
-
-
0038316325
-
Anatomical basis of tolerance and immunity to intestinal antigens
-
Mowat AM. Anatomical basis of tolerance and immunity to intestinal antigens. Nat Rev Immunol 2003 3 : 331 341.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 331-341
-
-
Mowat, A.M.1
-
21
-
-
44349167059
-
Dendritic cells in intestinal immune regulation
-
Coombes JL, Powrie F. Dendritic cells in intestinal immune regulation. Nat Rev Immunol 2008 8 : 435 446.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 435-446
-
-
Coombes, J.L.1
Powrie, F.2
-
22
-
-
0027301264
-
Localization of transforming growth factor beta isoforms in the normal murine small intestine and colon
-
Barnard JA, Warwick GJ, Gold LI. Localization of transforming growth factor beta isoforms in the normal murine small intestine and colon. Gastroenterology 1993 105 : 67 73.
-
(1993)
Gastroenterology
, vol.105
, pp. 67-73
-
-
Barnard, J.A.1
Warwick, G.J.2
Gold, L.I.3
-
23
-
-
18244387204
-
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells
-
Rimoldi M, et al. Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells. Nat Immunol 2005 6 : 507 514.
-
(2005)
Nat Immunol
, vol.6
, pp. 507-514
-
-
Rimoldi, M.1
-
24
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
-
Sun CM, et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med 2007 204 : 1775 1785.
-
(2007)
J Exp Med
, vol.204
, pp. 1775-1785
-
-
Sun, C.M.1
-
25
-
-
34547788180
-
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β- and retinoic acid-dependent mechanism
-
Coombes JL, et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β- and retinoic acid-dependent mechanism. J Exp Med 2007 204 : 1757 1764.
-
(2007)
J Exp Med
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
-
26
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
Mucida D, et al. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007 317 : 256 260.
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
-
27
-
-
22144479379
-
Oral tolerance in the absence of naturally occurring Tregs
-
Mucida D, Kutchukhidze N, Erazo A, Russo M, Lafaille JJ, Curotto de Lafaille MA. Oral tolerance in the absence of naturally occurring Tregs. J Clin Invest 2005 115 : 1923 1933.
-
(2005)
J Clin Invest
, vol.115
, pp. 1923-1933
-
-
Mucida, D.1
Kutchukhidze, N.2
Erazo, A.3
Russo, M.4
Lafaille, J.J.5
Curotto De Lafaille, M.A.6
-
28
-
-
34548764423
-
Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
-
Denning TL, Wang YC, Patel SR, Williams IR, Pulendran B. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nat Immunol 2007 8 : 1086 1094.
-
(2007)
Nat Immunol
, vol.8
, pp. 1086-1094
-
-
Denning, T.L.1
Wang, Y.C.2
Patel, S.R.3
Williams, I.R.4
Pulendran, B.5
-
29
-
-
34548208943
-
Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice
-
Travis MA, et al. Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice. Nature 2007 449 : 361 365.
-
(2007)
Nature
, vol.449
, pp. 361-365
-
-
Travis, M.A.1
-
30
-
-
35649024275
-
Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins
-
Lacy-Hulbert A, et al. Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins. Proc Natl Acad Sci USA 2007 104 : 15823 15828.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15823-15828
-
-
Lacy-Hulbert, A.1
-
31
-
-
70049099836
-
Intestinal lamina propria dendritic cell subsets have different origin and functions
-
Varol C, et al. Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity 2009 31 : 502 512.
-
(2009)
Immunity
, vol.31
, pp. 502-512
-
-
Varol, C.1
-
32
-
-
70049098070
-
Origin of the lamina propria dendritic cell network
-
Bogunovic M, et al. Origin of the lamina propria dendritic cell network. Immunity 2009 31 : 513 525.
-
(2009)
Immunity
, vol.31
, pp. 513-525
-
-
Bogunovic, M.1
-
33
-
-
69549084637
-
A role for CD47 in the development of experimental colitis mediated by SIRPalpha+CD103- dendritic cells
-
Fortin G, et al. A role for CD47 in the development of experimental colitis mediated by SIRPalpha+CD103- dendritic cells. J Exp Med 2009 206 : 1995 2011.
-
(2009)
J Exp Med
, vol.206
, pp. 1995-2011
-
-
Fortin, G.1
-
34
-
-
26844538936
-
Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing
-
Johansson-Lindbom B, et al. Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing. J Exp Med 2005 202 : 1063 1073.
-
(2005)
J Exp Med
, vol.202
, pp. 1063-1073
-
-
Johansson-Lindbom, B.1
-
35
-
-
0036099957
-
Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin
-
Stagg AJ, Kamm MA, Knight SC. Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin. Eur J Immunol 2002 32 : 1445 1454.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1445-1454
-
-
Stagg, A.J.1
Kamm, M.A.2
Knight, S.C.3
-
36
-
-
0141449950
-
Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): Requirement for GALT dendritic cells and adjuvant
-
Johansson-Lindbom B, Svensson M, Wurbel MA, Malissen B, Marquez G, Agace W. Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant. J Exp Med 2003 198 : 963 969.
-
(2003)
J Exp Med
, vol.198
, pp. 963-969
-
-
Johansson-Lindbom, B.1
Svensson, M.2
Wurbel, M.A.3
Malissen, B.4
Marquez, G.5
Agace, W.6
-
37
-
-
0038264036
-
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
-
Mora JR, et al. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 2003 424 : 88 93.
-
(2003)
Nature
, vol.424
, pp. 88-93
-
-
Mora, J.R.1
-
38
-
-
0042866144
-
Trophic and cytoprotective nutrition for intestinal adaptation, mucosal repair, and barrier function
-
Ziegler TR, Evans ME, Fernandez-Estivariz C, Jones DP. Trophic and cytoprotective nutrition for intestinal adaptation, mucosal repair, and barrier function. Annu Rev Nutr 2003 23 : 229 261.
-
(2003)
Annu Rev Nutr
, vol.23
, pp. 229-261
-
-
Ziegler, T.R.1
Evans, M.E.2
Fernandez-Estivariz, C.3
Jones, D.P.4
-
39
-
-
5644300399
-
Retinoic acid imprints gut-homing specificity on T cells
-
Iwata M, Hirakiyama A, Eshima Y, Kagechika H, Kato C, Song SY. Retinoic acid imprints gut-homing specificity on T cells. Immunity 2004 21 : 527 538.
-
(2004)
Immunity
, vol.21
, pp. 527-538
-
-
Iwata, M.1
Hirakiyama, A.2
Eshima, Y.3
Kagechika, H.4
Kato, C.5
Song, S.Y.6
-
40
-
-
33751223544
-
Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
-
Mora JR, et al. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science 2006 314 : 1157 1160.
-
(2006)
Science
, vol.314
, pp. 1157-1160
-
-
Mora, J.R.1
-
41
-
-
34249710939
-
Induction of organ-selective CD4(+) regulatory T cell homing
-
Siewert C, et al. Induction of organ-selective CD4(+) regulatory T cell homing. Eur J Immunol 2007 37 : 978 989.
-
(2007)
Eur J Immunol
, vol.37
, pp. 978-989
-
-
Siewert, C.1
-
42
-
-
35748934494
-
Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells
-
Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol 2007 179 : 3724 3733.
-
(2007)
J Immunol
, vol.179
, pp. 3724-3733
-
-
Kang, S.G.1
Lim, H.W.2
Andrisani, O.M.3
Broxmeyer, H.E.4
Kim, C.H.5
-
43
-
-
34548762585
-
Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation
-
Schambach F, Schupp M, Lazar MA, Reiner SL. Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation. Eur J Immunol 2007 37 : 2396 2399.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2396-2399
-
-
Schambach, F.1
Schupp, M.2
Lazar, M.A.3
Reiner, S.L.4
-
44
-
-
38949164425
-
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
-
Elias KM, et al. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 2008 111 : 1013 1020.
-
(2008)
Blood
, vol.111
, pp. 1013-1020
-
-
Elias, K.M.1
-
45
-
-
55549084247
-
Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells
-
Hill JA, et al. Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells. Immunity 2008 29 : 758 770.
-
(2008)
Immunity
, vol.29
, pp. 758-770
-
-
Hill, J.A.1
-
46
-
-
0030584795
-
Vitamin A down-regulation of IFN-gamma synthesis in cloned mouse Th1 lymphocytes depends on the CD28 costimulatory pathway
-
Cantorna MT, Nashold FE, Chun TY, Hayes CE. Vitamin A down-regulation of IFN-gamma synthesis in cloned mouse Th1 lymphocytes depends on the CD28 costimulatory pathway. J Immunol 1996 156 : 2674 2679.
-
(1996)
J Immunol
, vol.156
, pp. 2674-2679
-
-
Cantorna, M.T.1
Nashold, F.E.2
Chun, T.Y.3
Hayes, C.E.4
-
47
-
-
36749007248
-
Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells
-
Wei J, Duramad O, Perng OA, Reiner SL, Liu YJ, Qin FX. Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells. Proc Natl Acad Sci USA 2007 104 : 18169 18174.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 18169-18174
-
-
Wei, J.1
Duramad, O.2
Perng, O.A.3
Reiner, S.L.4
Liu, Y.J.5
Qin, F.X.6
-
48
-
-
64049110576
-
Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells
-
author reply 472-473.
-
Mucida D, et al. Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells. Immunity 2009 30 : 471 472 author reply 472-473.
-
(2009)
Immunity
, vol.30
, pp. 471-472
-
-
Mucida, D.1
-
49
-
-
35748968209
-
In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid
-
Saurer L, McCullough KC, Summerfield A. In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid. J Immunol 2007 179 : 3504 3514.
-
(2007)
J Immunol
, vol.179
, pp. 3504-3514
-
-
Saurer, L.1
McCullough, K.C.2
Summerfield, A.3
-
50
-
-
58149145656
-
Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo
-
Hammerschmidt SI, et al. Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo. J Exp Med 2008 205 : 2483 2490.
-
(2008)
J Exp Med
, vol.205
, pp. 2483-2490
-
-
Hammerschmidt, S.I.1
-
51
-
-
64149088746
-
Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity
-
Manicassamy S, et al. Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nat Med 2009 15 : 401 409.
-
(2009)
Nat Med
, vol.15
, pp. 401-409
-
-
Manicassamy, S.1
-
52
-
-
63649135273
-
GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity
-
Yokota A, et al. GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity. Int Immunol 2009 21 : 361 377.
-
(2009)
Int Immunol
, vol.21
, pp. 361-377
-
-
Yokota, A.1
-
53
-
-
33646596928
-
Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE
-
Liu Y, Teige I, Birnir B, Issazadeh-Navikas S. Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE. Nat Med 2006 12 : 518 525.
-
(2006)
Nat Med
, vol.12
, pp. 518-525
-
-
Liu, Y.1
Teige, I.2
Birnir, B.3
Issazadeh-Navikas, S.4
-
54
-
-
37349033910
-
Induction of regulatory T cells by physiological level estrogen
-
Tai P, et al. Induction of regulatory T cells by physiological level estrogen. J Cell Physiol 2008 214 : 456 464.
-
(2008)
J Cell Physiol
, vol.214
, pp. 456-464
-
-
Tai, P.1
-
55
-
-
34748873441
-
Regulatory T cells and infection: A dangerous necessity
-
Belkaid Y. Regulatory T cells and infection: a dangerous necessity. Nat Rev Immunol 2007 7 : 875 888.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 875-888
-
-
Belkaid, Y.1
-
56
-
-
46249099691
-
Trypanosoma cruzi induces regulatory dendritic cells in vitro
-
Poncini CV, Alba Soto CD, Batalla E, Solana ME, Gonzalez Cappa SM. Trypanosoma cruzi induces regulatory dendritic cells in vitro. Infect Immun 2008 76 : 2633 2641.
-
(2008)
Infect Immun
, vol.76
, pp. 2633-2641
-
-
Poncini, C.V.1
Alba Soto, C.D.2
Batalla, E.3
Solana, M.E.4
Gonzalez Cappa, S.M.5
-
57
-
-
24944466472
-
Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection
-
Walther M, et al. Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity 2005 23 : 287 296.
-
(2005)
Immunity
, vol.23
, pp. 287-296
-
-
Walther, M.1
-
58
-
-
34250658895
-
Role of TGF-beta and PGE2 in T cell responses during Plasmodium yoelii infection
-
Ocana-Morgner C, Wong KA, Lega F, Dotor J, Borras-Cuesta F, Rodriguez A. Role of TGF-beta and PGE2 in T cell responses during Plasmodium yoelii infection. Eur J Immunol 2007 37 : 1562 1574.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1562-1574
-
-
Ocana-Morgner, C.1
Wong, K.A.2
Lega, F.3
Dotor, J.4
Borras-Cuesta, F.5
Rodriguez, A.6
-
59
-
-
34447575642
-
Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection
-
Finney CA, Taylor MD, Wilson MS, Maizels RM. Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection. Eur J Immunol 2007 37 : 1874 1886.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1874-1886
-
-
Finney, C.A.1
Taylor, M.D.2
Wilson, M.S.3
Maizels, R.M.4
-
60
-
-
27144486144
-
Suppression of allergic airway inflammation by helminth-induced regulatory T cells
-
Wilson MS, Taylor MD, Balic A, Finney CA, Lamb JR, Maizels RM. Suppression of allergic airway inflammation by helminth-induced regulatory T cells. J Exp Med 2005 202 : 1199 1212.
-
(2005)
J Exp Med
, vol.202
, pp. 1199-1212
-
-
Wilson, M.S.1
Taylor, M.D.2
Balic, A.3
Finney, C.A.4
Lamb, J.R.5
Maizels, R.M.6
-
61
-
-
57449084307
-
Expansion of Foxp3+ regulatory T cells in mice infected with the filarial parasite Brugia malayi
-
McSorley HJ, Harcus YM, Murray J, Taylor MD, Maizels RM. Expansion of Foxp3+ regulatory T cells in mice infected with the filarial parasite Brugia malayi. J Immunol 2008 181 : 6456 6466.
-
(2008)
J Immunol
, vol.181
, pp. 6456-6466
-
-
McSorley, H.J.1
Harcus, Y.M.2
Murray, J.3
Taylor, M.D.4
Maizels, R.M.5
-
62
-
-
61449211034
-
Regulatory T cells: A role in the control of helminth-driven intestinal pathology and worm survival
-
D'Elia R, Behnke JM, Bradley JE, Else KJ. Regulatory T cells: a role in the control of helminth-driven intestinal pathology and worm survival. J Immunol 2009 182 : 2340 2348.
-
(2009)
J Immunol
, vol.182
, pp. 2340-2348
-
-
D'Elia, R.1
Behnke, J.M.2
Bradley, J.E.3
Else, K.J.4
-
63
-
-
40949164727
-
CTLA-4 and CD4+ CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo
-
Taylor MD, et al. CTLA-4 and CD4+ CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo. J Immunol 2007 179 : 4626 4634.
-
(2007)
J Immunol
, vol.179
, pp. 4626-4634
-
-
Taylor, M.D.1
-
64
-
-
67650355471
-
Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity
-
Hewitson JP, Grainger JR, Maizels RM. Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity. Mol Biochem Parasitol 2009 167 : 1 11.
-
(2009)
Mol Biochem Parasitol
, vol.167
, pp. 1-11
-
-
Hewitson, J.P.1
Grainger, J.R.2
Maizels, R.M.3
-
65
-
-
9244249137
-
Selective maturation of dendritic cells by Nippostrongylus brasiliensis-secreted proteins drives Th2 immune responses
-
Balic A, Harcus Y, Holland MJ, Maizels RM. Selective maturation of dendritic cells by Nippostrongylus brasiliensis-secreted proteins drives Th2 immune responses. Eur J Immunol 2004 34 : 3047 3059.
-
(2004)
Eur J Immunol
, vol.34
, pp. 3047-3059
-
-
Balic, A.1
Harcus, Y.2
Holland, M.J.3
Maizels, R.M.4
-
66
-
-
34447547494
-
Impairment of dendritic cell function by excretory-secretory products: A potential mechanism for nematode-induced immunosuppression
-
Segura M, Su Z, Piccirillo C, Stevenson MM. Impairment of dendritic cell function by excretory-secretory products: a potential mechanism for nematode-induced immunosuppression. Eur J Immunol 2007 37 : 1887 1904.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1887-1904
-
-
Segura, M.1
Su, Z.2
Piccirillo, C.3
Stevenson, M.M.4
-
67
-
-
75149186869
-
Daf-7-related TGF-beta homologues from Trichostrongyloid nematodes show contrasting life-cycle expression patterns
-
McSorley HJ, et al. daf-7-related TGF-beta homologues from Trichostrongyloid nematodes show contrasting life-cycle expression patterns. Parasitology 2009 137 : 159 171.
-
(2009)
Parasitology
, vol.137
, pp. 159-171
-
-
McSorley, H.J.1
-
68
-
-
0030848465
-
A member of the TGF-beta receptor gene family in the parasitic nematode Brugia pahangi
-
Gomez-Escobar N, van den Biggelaar A, Maizels R. A member of the TGF-beta receptor gene family in the parasitic nematode Brugia pahangi. Gene 1997 199 : 101 109.
-
(1997)
Gene
, vol.199
, pp. 101-109
-
-
Gomez-Escobar, N.1
Van Den Biggelaar, A.2
Maizels, R.3
-
69
-
-
0033785339
-
Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi
-
Gomez-Escobar N, Gregory WF, Maizels RM. Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi. Infect Immun 2000 68 : 6402 6410.
-
(2000)
Infect Immun
, vol.68
, pp. 6402-6410
-
-
Gomez-Escobar, N.1
Gregory, W.F.2
Maizels, R.M.3
-
70
-
-
0029052370
-
The gp15/400 polyprotein antigen of Brugia malayi binds fatty acids and retinoids
-
Kennedy MW, Allen JE, Wright AS, McCruden AB, Cooper A. The gp15/400 polyprotein antigen of Brugia malayi binds fatty acids and retinoids. Mol Biochem Parasitol 1995 71 : 41 50.
-
(1995)
Mol Biochem Parasitol
, vol.71
, pp. 41-50
-
-
Kennedy, M.W.1
Allen, J.E.2
Wright, A.S.3
McCruden, A.B.4
Cooper, A.5
-
71
-
-
43749120513
-
The secretome of the filarial parasite, Brugia malayi: Proteomic profile of adult excretory-secretory products
-
Hewitson JP, et al. The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory-secretory products. Mol Biochem Parasitol 2008 160 : 8 21.
-
(2008)
Mol Biochem Parasitol
, vol.160
, pp. 8-21
-
-
Hewitson, J.P.1
-
72
-
-
33847269251
-
Debugging how bacteria manipulate the immune response
-
Sansonetti PJ, Di Santo JP. Debugging how bacteria manipulate the immune response. Immunity 2007 26 : 149 161.
-
(2007)
Immunity
, vol.26
, pp. 149-161
-
-
Sansonetti, P.J.1
Di Santo, J.P.2
-
74
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997 388 : 394 397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway, Jr.C.A.3
-
75
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004 118 : 229 241.
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
76
-
-
33845910419
-
Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement
-
Chieppa M, Rescigno M, Huang AY, Germain RN. Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement. J Exp Med 2006 203 : 2841 2852.
-
(2006)
J Exp Med
, vol.203
, pp. 2841-2852
-
-
Chieppa, M.1
Rescigno, M.2
Huang, A.Y.3
Germain, R.N.4
-
77
-
-
2442660296
-
Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy
-
Bashir ME, Louie S, Shi HN, Nagler-Anderson C. Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy. J Immunol 2004 172 : 6978 6987.
-
(2004)
J Immunol
, vol.172
, pp. 6978-6987
-
-
Bashir, M.E.1
Louie, S.2
Shi, H.N.3
Nagler-Anderson, C.4
-
78
-
-
33745851174
-
Toll-like receptors on regulatory T cells: Expanding immune regulation
-
Sutmuller RP, Morgan ME, Netea MG, Grauer O, Adema GJ. Toll-like receptors on regulatory T cells: expanding immune regulation. Trends Immunol 2006 27 : 387 393.
-
(2006)
Trends Immunol
, vol.27
, pp. 387-393
-
-
Sutmuller, R.P.1
Morgan, M.E.2
Netea, M.G.3
Grauer, O.4
Adema, G.J.5
-
79
-
-
0037450804
-
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
-
Caramalho I, Lopes-Carvalho T, Ostler D, Zelenay S, Haury M, Demengeot J. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med 2003 197 : 403 411.
-
(2003)
J Exp Med
, vol.197
, pp. 403-411
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
Zelenay, S.4
Haury, M.5
Demengeot, J.6
-
80
-
-
29144534608
-
Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells
-
Crellin NK, Garcia RV, Hadisfar O, Allan SE, Steiner TS, Levings MK. Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J Immunol 2005 75 : 8051 8059.
-
(2005)
J Immunol
, vol.75
, pp. 8051-8059
-
-
Crellin, N.K.1
Garcia, R.V.2
Hadisfar, O.3
Allan, S.E.4
Steiner, T.S.5
Levings, M.K.6
-
81
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
Pasare C, Medzhitov R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 2003 299 : 1033 1036.
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
82
-
-
23944509107
-
Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function
-
Peng G, et al. Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science 2005 309 : 1380 1384.
-
(2005)
Science
, vol.309
, pp. 1380-1384
-
-
Peng, G.1
-
83
-
-
32444432610
-
Toll-like receptor 2 controls expansion and function of regulatory T cells
-
Sutmuller RP, et al. Toll-like receptor 2 controls expansion and function of regulatory T cells. J Clin Invest 2006 116 : 485 494.
-
(2006)
J Clin Invest
, vol.116
, pp. 485-494
-
-
Sutmuller, R.P.1
-
84
-
-
33646487278
-
Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells
-
Liu H, Komai-Koma M, Xu D, Liew FY. Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci USA 2006 103 : 7048 7053.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7048-7053
-
-
Liu, H.1
Komai-Koma, M.2
Xu, D.3
Liew, F.Y.4
-
85
-
-
33846703313
-
CpG DNA inhibits CD4+CD25+ Treg suppression through direct MyD88-dependent costimulation of effector CD4+ T cells
-
Larosa DF, Gelman AE, Rahman AH, Zhang J, Turka LA, Walsh PT. CpG DNA inhibits CD4+CD25+ Treg suppression through direct MyD88-dependent costimulation of effector CD4+ T cells. Immunol Lett 2007 108 : 183 188.
-
(2007)
Immunol Lett
, vol.108
, pp. 183-188
-
-
Larosa, D.F.1
Gelman, A.E.2
Rahman, A.H.3
Zhang, J.4
Turka, L.A.5
Walsh, P.T.6
-
86
-
-
33845578705
-
Immunomodulatory effects associated with a live vaccine against Leishmania major containing CpG oligodeoxynucleotides
-
Wu W, Weigand L, Belkaid Y, Mendez S. Immunomodulatory effects associated with a live vaccine against Leishmania major containing CpG oligodeoxynucleotides. Eur J Immunol 2006 36 : 3238 3247.
-
(2006)
Eur J Immunol
, vol.36
, pp. 3238-3247
-
-
Wu, W.1
Weigand, L.2
Belkaid, Y.3
Mendez, S.4
-
87
-
-
3242732415
-
Crohn's disease is associated with a toll-like receptor-9 polymorphism
-
Torok HP, Glas J, Tonenchi L, Bruennler G, Folwaczny M, Folwaczny C. Crohn's disease is associated with a toll-like receptor-9 polymorphism. Gastroenterology 2004 127 : 365 366.
-
(2004)
Gastroenterology
, vol.127
, pp. 365-366
-
-
Torok, H.P.1
Glas, J.2
Tonenchi, L.3
Bruennler, G.4
Folwaczny, M.5
Folwaczny, C.6
-
88
-
-
53349164200
-
Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses
-
Hall JA, et al. Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses. Immunity 2008 29 : 637 649.
-
(2008)
Immunity
, vol.29
, pp. 637-649
-
-
Hall, J.A.1
-
89
-
-
31844433093
-
Activation of toll-like receptor 9 by DNA from different bacterial species
-
Dalpke A, Frank J, Peter M, Heeg K. Activation of toll-like receptor 9 by DNA from different bacterial species. Infect Immun 2006 74 : 940 946.
-
(2006)
Infect Immun
, vol.74
, pp. 940-946
-
-
Dalpke, A.1
Frank, J.2
Peter, M.3
Heeg, K.4
-
90
-
-
33751551466
-
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
-
Lee J, et al. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol 2006 8 : 1327 1336.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1327-1336
-
-
Lee, J.1
-
91
-
-
34248397191
-
Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA
-
Ewaschuk JB, Backer JL, Churchill TA, Obermeier F, Krause DO, Madsen KL. Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA. Infect Immun 2007 75 : 2572 2579.
-
(2007)
Infect Immun
, vol.75
, pp. 2572-2579
-
-
Ewaschuk, J.B.1
Backer, J.L.2
Churchill, T.A.3
Obermeier, F.4
Krause, D.O.5
Madsen, K.L.6
-
92
-
-
14644403009
-
Toll-like receptor 9-induced type i IFN protects mice from experimental colitis
-
Katakura K, Lee J, Rachmilewitz D, Li G, Eckmann L, Raz E. Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J Clin Invest 2005 115 : 695 702.
-
(2005)
J Clin Invest
, vol.115
, pp. 695-702
-
-
Katakura, K.1
Lee, J.2
Rachmilewitz, D.3
Li, G.4
Eckmann, L.5
Raz, E.6
-
93
-
-
0035843993
-
Commensal host-bacterial relationships in the gut
-
Hooper LV, Gordon JI. Commensal host-bacterial relationships in the gut. Science 2001 292 : 1115 1118.
-
(2001)
Science
, vol.292
, pp. 1115-1118
-
-
Hooper, L.V.1
Gordon, J.I.2
-
94
-
-
33745594044
-
The gut flora as a forgotten organ
-
O'Hara AM, Shanahan F. The gut flora as a forgotten organ. EMBO Rep 2006 7 : 688 693.
-
(2006)
EMBO Rep
, vol.7
, pp. 688-693
-
-
O'Hara, A.M.1
Shanahan, F.2
-
95
-
-
10744233159
-
Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis
-
Rachmilewitz D, et al. Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. Gastroenterology 2004 126 : 520 528.
-
(2004)
Gastroenterology
, vol.126
, pp. 520-528
-
-
Rachmilewitz, D.1
-
96
-
-
0036241068
-
Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis
-
Rachmilewitz D, et al. Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis. Gastroenterology 2002 122 : 1428 1441.
-
(2002)
Gastroenterology
, vol.122
, pp. 1428-1441
-
-
Rachmilewitz, D.1
-
97
-
-
20244372724
-
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
-
Fukata M, et al. Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol 2005 288 : G1055 G1065.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
-
-
Fukata, M.1
-
98
-
-
33644775552
-
The role of Toll-like receptors in immune disorders
-
Uematsu S, Akira S. The role of Toll-like receptors in immune disorders. Expert Opin Biol Ther 2006 6 : 203 214.
-
(2006)
Expert Opin Biol Ther
, vol.6
, pp. 203-214
-
-
Uematsu, S.1
Akira, S.2
-
99
-
-
2342442430
-
Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease
-
Ott SJ, et al. Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut 2004 53 : 685 693.
-
(2004)
Gut
, vol.53
, pp. 685-693
-
-
Ott, S.J.1
-
100
-
-
3242737791
-
Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer
-
Martin HM, et al. Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer. Gastroenterology 2004 127 : 80 93.
-
(2004)
Gastroenterology
, vol.127
, pp. 80-93
-
-
Martin, H.M.1
-
101
-
-
0038349279
-
Regulatory and functional co-operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn's disease
-
Barnich N, Boudeau J, Claret L, Darfeuille-Michaud A. Regulatory and functional co-operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn's disease. Mol Microbiol 2003 48 : 781 794.
-
(2003)
Mol Microbiol
, vol.48
, pp. 781-794
-
-
Barnich, N.1
Boudeau, J.2
Claret, L.3
Darfeuille-Michaud, A.4
-
102
-
-
22144476548
-
Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease
-
Swidsinski A, Weber J, Loening-Baucke V, Hale LP, Lochs H. Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol 2005 43 : 3380 3389.
-
(2005)
J Clin Microbiol
, vol.43
, pp. 3380-3389
-
-
Swidsinski, A.1
Weber, J.2
Loening-Baucke, V.3
Hale, L.P.4
Lochs, H.5
-
103
-
-
0035056544
-
Genetically related Escherichia coli strains associated with Crohn's disease
-
Masseret E, et al. Genetically related Escherichia coli strains associated with Crohn's disease. Gut 2001 48 : 320 325.
-
(2001)
Gut
, vol.48
, pp. 320-325
-
-
Masseret, E.1
-
104
-
-
0037302961
-
Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon
-
Seksik P, et al. Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon. Gut 2003 52 : 237 242.
-
(2003)
Gut
, vol.52
, pp. 237-242
-
-
Seksik, P.1
-
105
-
-
4143069158
-
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
-
Darfeuille-Michaud A, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology 2004 127 : 412 421.
-
(2004)
Gastroenterology
, vol.127
, pp. 412-421
-
-
Darfeuille-Michaud, A.1
-
106
-
-
0032514616
-
Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs
-
Krieg AM, et al. Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs. Proc Natl Acad Sci USA 1998 95 : 12631 12636.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12631-12636
-
-
Krieg, A.M.1
-
107
-
-
0034932263
-
Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs
-
Chen Y, et al. Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs. Gene Ther 2001 8 : 1024 1032.
-
(2001)
Gene Ther
, vol.8
, pp. 1024-1032
-
-
Chen, Y.1
-
108
-
-
0033762213
-
Requirements for effective inhibition of immunostimulatory CpG motifs by neutralizing motifs
-
Zhao H, Cheng SH, Yew NS. Requirements for effective inhibition of immunostimulatory CpG motifs by neutralizing motifs. Antisense Nucleic Acid Drug Dev 2000 10 : 381 389.
-
(2000)
Antisense Nucleic Acid Drug Dev
, vol.10
, pp. 381-389
-
-
Zhao, H.1
Cheng, S.H.2
Yew, N.S.3
-
109
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006 24 : 179 189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
110
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn T, et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 2007 448 : 484 487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
-
111
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva R, et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007 448 : 480 483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
-
112
-
-
33747593830
-
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
-
Stumhofer JS, et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol 2006 7 : 937 945.
-
(2006)
Nat Immunol
, vol.7
, pp. 937-945
-
-
Stumhofer, J.S.1
-
113
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007 8 : 967 974.
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
-
114
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol 2005 6 : 1219 1227.
-
(2005)
Nat Immunol
, vol.6
, pp. 1219-1227
-
-
Kretschmer, K.1
Apostolou, I.2
Hawiger, D.3
Khazaie, K.4
Nussenzweig, M.C.5
Von Boehmer, H.6
-
115
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005 22 : 329 341.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
116
-
-
48749107414
-
Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii
-
Dunay IR, et al. Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii. Immunity 2008 29 : 306 317.
-
(2008)
Immunity
, vol.29
, pp. 306-317
-
-
Dunay, I.R.1
-
117
-
-
70449532980
-
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
-
Oldenhove G, et al. Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity 2009 31 : 772 786.
-
(2009)
Immunity
, vol.31
, pp. 772-786
-
-
Oldenhove, G.1
-
118
-
-
41549160626
-
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis
-
Izcue A, et al. Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis. Immunity 2008 28 : 559 570.
-
(2008)
Immunity
, vol.28
, pp. 559-570
-
-
Izcue, A.1
-
119
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
-
Zheng Y, et al. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature 2009 458 : 351 356.
-
(2009)
Nature
, vol.458
, pp. 351-356
-
-
Zheng, Y.1
-
120
-
-
65749103365
-
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
-
Koch MA, Tucker-Heard G, Perdue NR, Killebrew JR, Urdahl KB, Campbell DJ. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat Immunol 2009 10 : 1 7.
-
(2009)
Nat Immunol
, vol.10
, pp. 1-7
-
-
Koch, M.A.1
Tucker-Heard, G.2
Perdue, N.R.3
Killebrew, J.R.4
Urdahl, K.B.5
Campbell, D.J.6
-
121
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee YK, et al. Late developmental plasticity in the T helper 17 lineage. Immunity 2009 30 : 92 107.
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
-
122
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
-
Wei G, et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 2009 30 : 155 167.
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
-
123
-
-
34249799285
-
Cutting edge: Regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta
-
Xu L, Kitani A, Fuss I, Strober W. Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J Immunol 2007 178 : 6725 6729.
-
(2007)
J Immunol
, vol.178
, pp. 6725-6729
-
-
Xu, L.1
Kitani, A.2
Fuss, I.3
Strober, W.4
-
124
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
-
Yang XO, et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 2008 28 : 29 39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
-
125
-
-
9244223651
-
Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity
-
Stock P, Akbari O, Berry G, Freeman GJ, Dekruyff RH, Umetsu DT. Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nat Immunol 2004 5 : 1149 1156.
-
(2004)
Nat Immunol
, vol.5
, pp. 1149-1156
-
-
Stock, P.1
Akbari, O.2
Berry, G.3
Freeman, G.J.4
Dekruyff, R.H.5
Umetsu, D.T.6
-
126
-
-
22344434572
-
IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
-
Sawitzki B, Kingsley CI, Oliveira V, Karim M, Herber M, Wood KJ. IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo. J Exp Med 2005 201 : 1925 1935.
-
(2005)
J Exp Med
, vol.201
, pp. 1925-1935
-
-
Sawitzki, B.1
Kingsley, C.I.2
Oliveira, V.3
Karim, M.4
Herber, M.5
Wood, K.J.6
-
127
-
-
33645102841
-
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires
-
Hsieh CS, Zheng Y, Liang Y, Fontenot JD, Rudensky AY. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat Immunol 2006 7 : 401 410.
-
(2006)
Nat Immunol
, vol.7
, pp. 401-410
-
-
Hsieh, C.S.1
Zheng, Y.2
Liang, Y.3
Fontenot, J.D.4
Rudensky, A.Y.5
-
128
-
-
69049107358
-
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
-
Zhou X, et al. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nat Immunol 2009 10 : 1000 1007.
-
(2009)
Nat Immunol
, vol.10
, pp. 1000-1007
-
-
Zhou, X.1
-
129
-
-
4544241811
-
Tolerance, not immunity, crucially depends on IL-2
-
Malek TR, Bayer AL. Tolerance, not immunity, crucially depends on IL-2. Nat Rev Immunol 2004 4 : 665 674.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 665-674
-
-
Malek, T.R.1
Bayer, A.L.2
-
130
-
-
33745296472
-
Indexation as a novel mechanism of lymphocyte homeostasis: The number of CD4+CD25+ regulatory T cells is indexed to the number of IL-2-producing cells
-
Almeida AR, Zaragoza B, Freitas AA. Indexation as a novel mechanism of lymphocyte homeostasis: the number of CD4+CD25+ regulatory T cells is indexed to the number of IL-2-producing cells. J Immunol 2006 177 : 192 200.
-
(2006)
J Immunol
, vol.177
, pp. 192-200
-
-
Almeida, A.R.1
Zaragoza, B.2
Freitas, A.A.3
-
131
-
-
27744461314
-
IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508
-
Hwang ES, Hong JH, Glimcher LH. IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508. J Exp Med 2005 202 : 1289 1300.
-
(2005)
J Exp Med
, vol.202
, pp. 1289-1300
-
-
Hwang, E.S.1
Hong, J.H.2
Glimcher, L.H.3
-
132
-
-
33846419491
-
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals
-
Villarino AV, et al. Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals. J Exp Med 2007 204 : 65 71.
-
(2007)
J Exp Med
, vol.204
, pp. 65-71
-
-
Villarino, A.V.1
-
133
-
-
43049174722
-
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
-
Tang Q, et al. Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity 2008 28 : 687 697.
-
(2008)
Immunity
, vol.28
, pp. 687-697
-
-
Tang, Q.1
-
134
-
-
51549104932
-
IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development
-
Vang KB, Yang J, Mahmud SA, Burchill MA, Vegoe AL, Farrar MA. IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development. J Immunol 2008 181 : 3285 3290.
-
(2008)
J Immunol
, vol.181
, pp. 3285-3290
-
-
Vang, K.B.1
Yang, J.2
Mahmud, S.A.3
Burchill, M.A.4
Vegoe, A.L.5
Farrar, M.A.6
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