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Volumn 66, Issue 19, 2009, Pages 3149-3160

Faithful after break-up: Suppression of chromosomal translocations

Author keywords

Chromosomal translocation; DNA repair; Double strand break; End joining; Homologous recombination

Indexed keywords

CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; DNA REPAIR; DNA STRAND BREAKAGE; DNA SYNTHESIS; DOUBLE STRANDED DNA BREAK; GENE FUNCTION; GENE REPRESSION; HUMAN; NONHUMAN; REVIEW; SACCHAROMYCES CEREVISIAE; SISTER CHROMATID; YEAST;

EID: 70349319253     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-009-0068-5     Document Type: Review
Times cited : (10)

References (127)
  • 1
    • 29444434887 scopus 로고    scopus 로고
    • Causes of oncogenic chromosomal translocation
    • 16257470 1:CAS:528:DC%2BD28Xkt1Wr
    • PD Aplan 2006 Causes of oncogenic chromosomal translocation Trends Genet 22 46 55 16257470 1:CAS:528:DC%2BD28Xkt1Wr
    • (2006) Trends Genet , vol.22 , pp. 46-55
    • Aplan, P.D.1
  • 2
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • 7969446 1:CAS:528:DyaK2cXmvFyjt7c%3D
    • TH Rabbitts 1994 Chromosomal translocations in human cancer Nature 372 143 149 7969446 1:CAS:528:DyaK2cXmvFyjt7c%3D
    • (1994) Nature , vol.372 , pp. 143-149
    • Rabbitts, T.H.1
  • 3
    • 0022847986 scopus 로고
    • Chromosomal approaches to the molecular basis of neoplasia
    • 3321306 1:STN:280:DyaL1c%2FpvVyisQ%3D%3D
    • PC Nowell CM Croce 1986 Chromosomal approaches to the molecular basis of neoplasia Symp Fundam Cancer Res 39 17 29 3321306 1:STN:280: DyaL1c%2FpvVyisQ%3D%3D
    • (1986) Symp Fundam Cancer Res , vol.39 , pp. 17-29
    • Nowell, P.C.1    Croce, C.M.2
  • 4
    • 33747873409 scopus 로고    scopus 로고
    • Chromatin structural elements and chromosomal translocations in leukemia
    • 1:CAS:528:DC%2BD28XptFSrt7c%3D
    • Y Zhang JD Rowley 2006 Chromatin structural elements and chromosomal translocations in leukemia DNA Repair (Amst) 5 1282 1297 1:CAS:528: DC%2BD28XptFSrt7c%3D
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1282-1297
    • Zhang, Y.1    Rowley, J.D.2
  • 5
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • 9708741 1:CAS:528:DyaK1cXlsVWjsL4%3D
    • SE Lee JK Moore A Holmes K Umezu RD Kolodner JE Haber 1998 Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage Cell 94 399 409 9708741 1:CAS:528:DyaK1cXlsVWjsL4%3D
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.D.5    Haber, J.E.6
  • 6
    • 38049115657 scopus 로고    scopus 로고
    • The mechanism of human nonhomologous DNA end joining
    • 17999957 1:CAS:528:DC%2BD1cXhtVOnug%3D%3D
    • MR Lieber 2008 The mechanism of human nonhomologous DNA end joining J Biol Chem 283 1 5 17999957 1:CAS:528:DC%2BD1cXhtVOnug%3D%3D
    • (2008) J Biol Chem , vol.283 , pp. 1-5
    • Lieber, M.R.1
  • 7
    • 33747877763 scopus 로고    scopus 로고
    • Transpositions and translocations induced by site-specific double-strand breaks in budding yeast
    • 1:CAS:528:DC%2BD28XptFSrtL8%3D
    • JE Haber 2006 Transpositions and translocations induced by site-specific double-strand breaks in budding yeast DNA Repair (Amst) 5 998 1009 1:CAS:528:DC%2BD28XptFSrtL8%3D
    • (2006) DNA Repair (Amst) , vol.5 , pp. 998-1009
    • Haber, J.E.1
  • 8
    • 54849404458 scopus 로고    scopus 로고
    • MMEJ repair of double-strand breaks (director's cut): Deleted sequences and alternative endings
    • 18809224 1:CAS:528:DC%2BD1cXhtlaqurbO
    • M McVey SE Lee 2008 MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings Trends Genet 24 529 538 18809224 1:CAS:528:DC%2BD1cXhtlaqurbO
    • (2008) Trends Genet , vol.24 , pp. 529-538
    • McVey, M.1    Lee, S.E.2
  • 9
    • 10344263324 scopus 로고    scopus 로고
    • Recombination proteins in yeast
    • 15568977 1:CAS:528:DC%2BD2MXltlOqtA%3D%3D
    • BO Krogh LS Symington 2004 Recombination proteins in yeast Annu Rev Genet 38 233 271 15568977 1:CAS:528:DC%2BD2MXltlOqtA%3D%3D
    • (2004) Annu Rev Genet , vol.38 , pp. 233-271
    • Krogh, B.O.1    Symington, L.S.2
  • 10
    • 29244463205 scopus 로고    scopus 로고
    • Nonhomologous end joining in yeast
    • 16285867 1:CAS:528:DC%2BD28Xlt1WrtQ%3D%3D
    • JM Daley PL Palmbos D Wu TE Wilson 2005 Nonhomologous end joining in yeast Annu Rev Genet 39 431 451 16285867 1:CAS:528:DC%2BD28Xlt1WrtQ%3D%3D
    • (2005) Annu Rev Genet , vol.39 , pp. 431-451
    • Daley, J.M.1    Palmbos, P.L.2    Wu, D.3    Wilson, T.E.4
  • 11
    • 0034732239 scopus 로고    scopus 로고
    • DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
    • 10761921 1:CAS:528:DC%2BD3cXisFSrtrg%3D
    • MJ Difilippantonio J Zhu HT Chen E Meffre MC Nussenzweig EE Max T Ried A Nussenzweig 2000 DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation Nature 404 510 514 10761921 1:CAS:528: DC%2BD3cXisFSrtrg%3D
    • (2000) Nature , vol.404 , pp. 510-514
    • Difilippantonio, M.J.1    Zhu, J.2    Chen, H.T.3    Meffre, E.4    Nussenzweig, M.C.5    Max, E.E.6    Ried, T.7    Nussenzweig, A.8
  • 12
    • 33747888634 scopus 로고    scopus 로고
    • Modeling oncogenic translocations: Distinct roles for double-strand break repair pathways in translocation formation in mammalian cells
    • 1:CAS:528:DC%2BD28XptFSrsbY%3D
    • DM Weinstock CA Richardson B Elliott M Jasin 2006 Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells DNA Repair (Amst) 5 1065 1074 1:CAS:528:DC%2BD28XptFSrsbY%3D
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1065-1074
    • Weinstock, D.M.1    Richardson, C.A.2    Elliott, B.3    Jasin, M.4
  • 13
    • 0034612308 scopus 로고    scopus 로고
    • The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations
    • 10823907 1:CAS:528:DC%2BD3cXktFais7o%3D
    • DO Ferguson JM Sekiguchi S Chang KM Frank Y Gao RA DePinho FW Alt 2000 The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations Proc Natl Acad Sci USA 97 6630 6633 10823907 1:CAS:528:DC%2BD3cXktFais7o%3D
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6630-6633
    • Ferguson, D.O.1    Sekiguchi, J.M.2    Chang, S.3    Frank, K.M.4    Gao, Y.5    Depinho, R.A.6    Alt, F.W.7
  • 14
    • 0037178722 scopus 로고    scopus 로고
    • Maintenance of genome stability in Saccharomyces cerevisiae
    • 12142524 1:CAS:528:DC%2BD38XlslWkur0%3D
    • RD Kolodner CD Putnam K Myung 2002 Maintenance of genome stability in Saccharomyces cerevisiae Science 297 552 557 12142524 1:CAS:528: DC%2BD38XlslWkur0%3D
    • (2002) Science , vol.297 , pp. 552-557
    • Kolodner, R.D.1    Putnam, C.D.2    Myung, K.3
  • 15
    • 0347416973 scopus 로고    scopus 로고
    • Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms
    • 14690603 1:CAS:528:DC%2BD2cXhsVOlug%3D%3D
    • M Lopes C Cotta-Ramusino G Liberi M Foiani 2003 Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms Mol Cell 12 1499 1510 14690603 1:CAS:528:DC%2BD2cXhsVOlug%3D%3D
    • (2003) Mol Cell , vol.12 , pp. 1499-1510
    • Lopes, M.1    Cotta-Ramusino, C.2    Liberi, G.3    Foiani, M.4
  • 16
    • 0035830498 scopus 로고    scopus 로고
    • Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae
    • 11239397 1:CAS:528:DC%2BD3MXis1ejsb4%3D
    • K Myung A Datta RD Kolodner 2001 Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae Cell 104 397 408 11239397 1:CAS:528:DC%2BD3MXis1ejsb4%3D
    • (2001) Cell , vol.104 , pp. 397-408
    • Myung, K.1    Datta, A.2    Kolodner, R.D.3
  • 17
    • 14844286404 scopus 로고    scopus 로고
    • Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites
    • 15766523 1:CAS:528:DC%2BD2MXis1yhsb8%3D
    • FJ Lemoine NP Degtyareva K Lobachev TD Petes 2005 Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites Cell 120 587 598 15766523 1:CAS:528: DC%2BD2MXis1yhsb8%3D
    • (2005) Cell , vol.120 , pp. 587-598
    • Lemoine, F.J.1    Degtyareva, N.P.2    Lobachev, K.3    Petes, T.D.4
  • 18
  • 19
    • 30944462801 scopus 로고    scopus 로고
    • Cycles of chromosome instability are associated with a fragile site and are increased by defects in DNA replication and checkpoint controls in yeast
    • 16384935 1:CAS:528:DC%2BD28XptlKjtw%3D%3D
    • A Admire L Shanks N Danzl M Wang U Weier W Stevens E Hunt T Weinert 2006 Cycles of chromosome instability are associated with a fragile site and are increased by defects in DNA replication and checkpoint controls in yeast Genes Dev 20 159 173 16384935 1:CAS:528:DC%2BD28XptlKjtw%3D%3D
    • (2006) Genes Dev , vol.20 , pp. 159-173
    • Admire, A.1    Shanks, L.2    Danzl, N.3    Wang, M.4    Weier, U.5    Stevens, W.6    Hunt, E.7    Weinert, T.8
  • 20
    • 0014697617 scopus 로고
    • Delayed radiation effects in atomic-bomb survivors. Major observations by the Atomic Bomb Casualty Commission are evaluated
    • 4898614 1:STN:280:DyaE3c%2Fgt1ejsw%3D%3D
    • RW Miller 1969 Delayed radiation effects in atomic-bomb survivors. Major observations by the Atomic Bomb Casualty Commission are evaluated Science 166 569 574 4898614 1:STN:280:DyaE3c%2Fgt1ejsw%3D%3D
    • (1969) Science , vol.166 , pp. 569-574
    • Miller, R.W.1
  • 21
    • 33748138991 scopus 로고    scopus 로고
    • Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations
    • 1:CAS:528:DC%2BD28XptFSrt7o%3D
    • MR Lieber K Yu SC Raghavan 2006 Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations DNA Repair (Amst) 5 1234 1245 1:CAS:528:DC%2BD28XptFSrt7o%3D
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1234-1245
    • Lieber, M.R.1    Yu, K.2    Raghavan, S.C.3
  • 22
    • 33747882412 scopus 로고    scopus 로고
    • Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: New insights and new questions
    • 1:CAS:528:DC%2BD28XptFSrtrw%3D
    • PA Sung J Libura C Richardson 2006 Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions DNA Repair (Amst) 5 1109 1118 1:CAS:528:DC%2BD28XptFSrtrw%3D
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1109-1118
    • Sung, P.A.1    Libura, J.2    Richardson, C.3
  • 23
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • 10357855 1:STN:280:DyaK1M3os1eksA%3D%3D
    • F Paques JE Haber 1999 Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae Microbiol Mol Biol Rev 63 349 404 10357855 1:STN:280:DyaK1M3os1eksA%3D%3D
    • (1999) Microbiol Mol Biol Rev , vol.63 , pp. 349-404
    • Paques, F.1    Haber, J.E.2
  • 24
    • 33745872612 scopus 로고    scopus 로고
    • Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein
    • 16809776 1:CAS:528:DC%2BD28XmvFyht7k%3D
    • KH Schmidt J Wu RD Kolodner 2006 Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein Mol Cell Biol 26 5406 5420 16809776 1:CAS:528: DC%2BD28XmvFyht7k%3D
    • (2006) Mol Cell Biol , vol.26 , pp. 5406-5420
    • Schmidt, K.H.1    Wu, J.2    Kolodner, R.D.3
  • 25
    • 50249159576 scopus 로고    scopus 로고
    • Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast
    • 18591249 1:CAS:528:DC%2BD1cXhtVersLrE
    • FJ Lemoine NP Degtyareva RJ Kokoska TD Petes 2008 Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast Mol Cell Biol 28 5359 5368 18591249 1:CAS:528:DC%2BD1cXhtVersLrE
    • (2008) Mol Cell Biol , vol.28 , pp. 5359-5368
    • Lemoine, F.J.1    Degtyareva, N.P.2    Kokoska, R.J.3    Petes, T.D.4
  • 26
    • 49349085284 scopus 로고    scopus 로고
    • Chromosome fusions following telomere loss are mediated by single-strand annealing
    • 18722173 1:CAS:528:DC%2BD1cXhtVyksbvI
    • X Wang P Baumann 2008 Chromosome fusions following telomere loss are mediated by single-strand annealing Mol Cell 31 463 473 18722173 1:CAS:528:DC%2BD1cXhtVyksbvI
    • (2008) Mol Cell , vol.31 , pp. 463-473
    • Wang, X.1    Baumann, P.2
  • 28
    • 10944219768 scopus 로고    scopus 로고
    • Control of sister chromatid recombination by histone H2AX
    • 15610743 1:CAS:528:DC%2BD2MXjvVWjuw%3D%3D
    • A Xie N Puget I Shim S Odate I Jarzyna CH Bassing FW Alt R Scully 2004 Control of sister chromatid recombination by histone H2AX Mol Cell 16 1017 1025 15610743 1:CAS:528:DC%2BD2MXjvVWjuw%3D%3D
    • (2004) Mol Cell , vol.16 , pp. 1017-1025
    • Xie, A.1    Puget, N.2    Shim, I.3    Odate, S.4    Jarzyna, I.5    Bassing, C.H.6    Alt, F.W.7    Scully, R.8
  • 29
    • 0242605613 scopus 로고    scopus 로고
    • Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast
    • 12820977 1:CAS:528:DC%2BD3sXltlSrsr0%3D
    • S Gonzalez-Barrera F Cortes-Ledesma RE Wellinger A Aguilera 2003 Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast Mol Cell 11 1661 1671 12820977 1:CAS:528:DC%2BD3sXltlSrsr0%3D
    • (2003) Mol Cell , vol.11 , pp. 1661-1671
    • Gonzalez-Barrera, S.1    Cortes-Ledesma, F.2    Wellinger, R.E.3    Aguilera, A.4
  • 30
    • 0346351375 scopus 로고
    • A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
    • 4140506 1:STN:280:DyaE2M%2FmsFGmsg%3D%3D
    • RS Chaganti S Schonberg J German 1974 A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes Proc Natl Acad Sci USA 71 4508 4512 4140506 1:STN:280:DyaE2M%2FmsFGmsg%3D%3D
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 4508-4512
    • Chaganti, R.S.1    Schonberg, S.2    German, J.3
  • 31
    • 0031888685 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae RAD9 checkpoint reduces the DNA damage-associated stimulation of directed translocations
    • 9488434 1:CAS:528:DyaK1cXhtleitb4%3D
    • M Fasullo T Bennett P AhChing J Koudelik 1998 The Saccharomyces cerevisiae RAD9 checkpoint reduces the DNA damage-associated stimulation of directed translocations Mol Cell Biol 18 1190 1200 9488434 1:CAS:528: DyaK1cXhtleitb4%3D
    • (1998) Mol Cell Biol , vol.18 , pp. 1190-1200
    • Fasullo, M.1    Bennett, T.2    Ahching, P.3    Koudelik, J.4
  • 32
    • 36148992972 scopus 로고    scopus 로고
    • Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication
    • 17905819 1:CAS:528:DC%2BD2sXht1yktbrE
    • F Cortes-Ledesma C Tous A Aguilera 2007 Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication Nucleic Acids Res 35 6560 6570 17905819 1:CAS:528:DC%2BD2sXht1yktbrE
    • (2007) Nucleic Acids Res , vol.35 , pp. 6560-6570
    • Cortes-Ledesma, F.1    Tous, C.2    Aguilera, A.3
  • 33
    • 34250211440 scopus 로고    scopus 로고
    • Chromosome segregation and double-strand break repair-a complex connection
    • 17466504
    • L Strom C Sjogren 2007 Chromosome segregation and double-strand break repair-a complex connection Curr Opin Cell Biol 19 344 349 17466504
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 344-349
    • Strom, L.1    Sjogren, C.2
  • 34
    • 0037459376 scopus 로고    scopus 로고
    • Chromosomal cohesin forms a ring
    • 12654244 1:CAS:528:DC%2BD3sXivVWjsb0%3D
    • S Gruber CH Haering K Nasmyth 2003 Chromosomal cohesin forms a ring Cell 112 765 777 12654244 1:CAS:528:DC%2BD3sXivVWjsb0%3D
    • (2003) Cell , vol.112 , pp. 765-777
    • Gruber, S.1    Haering, C.H.2    Nasmyth, K.3
  • 35
    • 0036242551 scopus 로고    scopus 로고
    • Molecular architecture of SMC proteins and the yeast cohesin complex
    • 11983169 1:CAS:528:DC%2BD38XjsFWgsLk%3D
    • CH Haering J Lowe A Hochwagen K Nasmyth 2002 Molecular architecture of SMC proteins and the yeast cohesin complex Mol Cell 9 773 788 11983169 1:CAS:528:DC%2BD38XjsFWgsLk%3D
    • (2002) Mol Cell , vol.9 , pp. 773-788
    • Haering, C.H.1    Lowe, J.2    Hochwagen, A.3    Nasmyth, K.4
  • 36
    • 47549115780 scopus 로고    scopus 로고
    • The cohesin ring concatenates sister DNA molecules
    • 18596691 1:CAS:528:DC%2BD1cXosFCqt74%3D
    • CH Haering AM Farcas P Arumugam J Metson K Nasmyth 2008 The cohesin ring concatenates sister DNA molecules Nature 454 297 301 18596691 1:CAS:528:DC%2BD1cXosFCqt74%3D
    • (2008) Nature , vol.454 , pp. 297-301
    • Haering, C.H.1    Farcas, A.M.2    Arumugam, P.3    Metson, J.4    Nasmyth, K.5
  • 37
    • 33750021276 scopus 로고    scopus 로고
    • Evidence that loading of cohesin onto chromosomes involves opening of its SMC hinge
    • 17081975 1:CAS:528:DC%2BD28Xht1WhtbbJ
    • S Gruber P Arumugam Y Katou D Kuglitsch W Helmhart K Shirahige K Nasmyth 2006 Evidence that loading of cohesin onto chromosomes involves opening of its SMC hinge Cell 127 523 537 17081975 1:CAS:528:DC%2BD28Xht1WhtbbJ
    • (2006) Cell , vol.127 , pp. 523-537
    • Gruber, S.1    Arumugam, P.2    Katou, Y.3    Kuglitsch, D.4    Helmhart, W.5    Shirahige, K.6    Nasmyth, K.7
  • 38
    • 10944232673 scopus 로고    scopus 로고
    • Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair
    • 15610742
    • L Strom HB Lindroos K Shirahige C Sjogren 2004 Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair Mol Cell 16 1003 1015 15610742
    • (2004) Mol Cell , vol.16 , pp. 1003-1015
    • Strom, L.1    Lindroos, H.B.2    Shirahige, K.3    Sjogren, C.4
  • 39
    • 10944262393 scopus 로고    scopus 로고
    • DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain
    • 15610741
    • E Unal A Arbel-Eden U Sattler R Shroff M Lichten JE Haber D Koshland 2004 DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain Mol Cell 16 991 1002 15610741
    • (2004) Mol Cell , vol.16 , pp. 991-1002
    • Unal, E.1    Arbel-Eden, A.2    Sattler, U.3    Shroff, R.4    Lichten, M.5    Haber, J.E.6    Koshland, D.7
  • 40
    • 34447549077 scopus 로고    scopus 로고
    • Postreplicative formation of cohesion is required for repair and induced by a single DNA break
    • 17626884
    • L Strom C Karlsson HB Lindroos S Wedahl Y Katou K Shirahige C Sjogren 2007 Postreplicative formation of cohesion is required for repair and induced by a single DNA break Science 317 242 245 17626884
    • (2007) Science , vol.317 , pp. 242-245
    • Strom, L.1    Karlsson, C.2    Lindroos, H.B.3    Wedahl, S.4    Katou, Y.5    Shirahige, K.6    Sjogren, C.7
  • 44
    • 34547907083 scopus 로고    scopus 로고
    • RSC functions as an early double-strand-break sensor in the cell's response to DNA damage
    • 17689960 1:CAS:528:DC%2BD2sXpt1Knsrk%3D
    • B Liang J Qiu K Ratnakumar BC Laurent 2007 RSC functions as an early double-strand-break sensor in the cell's response to DNA damage Curr Biol 17 1432 1437 17689960 1:CAS:528:DC%2BD2sXpt1Knsrk%3D
    • (2007) Curr Biol , vol.17 , pp. 1432-1437
    • Liang, B.1    Qiu, J.2    Ratnakumar, K.3    Laurent, B.C.4
  • 46
    • 11244269445 scopus 로고    scopus 로고
    • The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
    • 15549137 1:CAS:528:DC%2BD2cXhtVGitr7F
    • Y Aylon B Liefshitz M Kupiec 2004 The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle EMBO J 23 4868 4875 15549137 1:CAS:528:DC%2BD2cXhtVGitr7F
    • (2004) EMBO J , vol.23 , pp. 4868-4875
    • Aylon, Y.1    Liefshitz, B.2    Kupiec, M.3
  • 47
    • 53349162987 scopus 로고    scopus 로고
    • CDK targets Sae2 to control DNA-end resection and homologous recombination
    • 18716619 1:CAS:528:DC%2BD1cXhtF2hsbjL
    • P Huertas F Cortes-Ledesma AA Sartori A Aguilera SP Jackson 2008 CDK targets Sae2 to control DNA-end resection and homologous recombination Nature 455 689 692 18716619 1:CAS:528:DC%2BD1cXhtF2hsbjL
    • (2008) Nature , vol.455 , pp. 689-692
    • Huertas, P.1    Cortes-Ledesma, F.2    Sartori, A.A.3    Aguilera, A.4    Jackson, S.P.5
  • 48
    • 53649090109 scopus 로고    scopus 로고
    • DNA helicases Sgs1 and BLM promote DNA double-strand break resection
    • 18923075 1:CAS:528:DC%2BD1cXht12ht7zF
    • S Gravel JR Chapman C Magill SP Jackson 2008 DNA helicases Sgs1 and BLM promote DNA double-strand break resection Genes Dev 22 2767 2772 18923075 1:CAS:528:DC%2BD1cXht12ht7zF
    • (2008) Genes Dev , vol.22 , pp. 2767-2772
    • Gravel, S.1    Chapman, J.R.2    Magill, C.3    Jackson, S.P.4
  • 49
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • 18806779 1:CAS:528:DC%2BD1cXht1WktLfP
    • EP Mimitou LS Symington 2008 Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing Nature 455 770 774 18806779 1:CAS:528: DC%2BD1cXht1WktLfP
    • (2008) Nature , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 50
    • 51549095956 scopus 로고    scopus 로고
    • Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
    • 18805091 1:CAS:528:DC%2BD1cXht1Sns7rM
    • Z Zhu WH Chung EY Shim SE Lee G Ira 2008 Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends Cell 134 981 994 18805091 1:CAS:528:DC%2BD1cXht1Sns7rM
    • (2008) Cell , vol.134 , pp. 981-994
    • Zhu, Z.1    Chung, W.H.2    Shim, E.Y.3    Lee, S.E.4    Ira, G.5
  • 51
    • 34447129653 scopus 로고    scopus 로고
    • Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination
    • 17589524 1:CAS:528:DC%2BD2sXnt1KgsrY%3D
    • Y Zhang ML Hefferin L Chen EY Shim HM Tseng Y Kwon P Sung SE Lee AE Tomkinson 2007 Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination Nat Struct Mol Biol 14 639 646 17589524 1:CAS:528:DC%2BD2sXnt1KgsrY%3D
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 639-646
    • Zhang, Y.1    Hefferin, M.L.2    Chen, L.3    Shim, E.Y.4    Tseng, H.M.5    Kwon, Y.6    Sung, P.7    Lee, S.E.8    Tomkinson, A.E.9
  • 52
    • 39549114009 scopus 로고    scopus 로고
    • Differential regulation of the cellular response to DNA double-strand breaks in G1
    • 18406328 1:CAS:528:DC%2BD1cXkvFegurc%3D
    • JH Barlow M Lisby R Rothstein 2008 Differential regulation of the cellular response to DNA double-strand breaks in G1 Mol Cell 30 73 85 18406328 1:CAS:528:DC%2BD1cXkvFegurc%3D
    • (2008) Mol Cell , vol.30 , pp. 73-85
    • Barlow, J.H.1    Lisby, M.2    Rothstein, R.3
  • 53
    • 33644691699 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends
    • 16162495 1:CAS:528:DC%2BD2MXht1SktLvL
    • M Clerici D Mantiero G Lucchini MP Longhese 2005 The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends J Biol Chem 280 38631 38638 16162495 1:CAS:528:DC%2BD2MXht1SktLvL
    • (2005) J Biol Chem , vol.280 , pp. 38631-38638
    • Clerici, M.1    Mantiero, D.2    Lucchini, G.3    Longhese, M.P.4
  • 55
    • 46949098616 scopus 로고    scopus 로고
    • Break dosage, cell cycle stage and DNA replication influence DNA double strand break response
    • 18511906 1:CAS:528:DC%2BD1cXot1emsLg%3D
    • C Zierhut JF Diffley 2008 Break dosage, cell cycle stage and DNA replication influence DNA double strand break response EMBO J 27 1875 1885 18511906 1:CAS:528:DC%2BD1cXot1emsLg%3D
    • (2008) EMBO J , vol.27 , pp. 1875-1885
    • Zierhut, C.1    Diffley, J.F.2
  • 56
    • 48649086824 scopus 로고    scopus 로고
    • The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle
    • 18600234 1:CAS:528:DC%2BD1cXpt1Snt7w%3D
    • M Clerici D Mantiero I Guerini G Lucchini MP Longhese 2008 The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle EMBO Rep 9 810 818 18600234 1:CAS:528:DC%2BD1cXpt1Snt7w%3D
    • (2008) EMBO Rep , vol.9 , pp. 810-818
    • Clerici, M.1    Mantiero, D.2    Guerini, I.3    Lucchini, G.4    Longhese, M.P.5
  • 59
    • 58149151222 scopus 로고    scopus 로고
    • Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae
    • 1:CAS:528:DC%2BD1MXktleqsA%3D%3D
    • BM Wasko CL Holland MA Resnick LK Lewis 2009 Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae DNA Repair (Amst) 8 162 169 1:CAS:528:DC%2BD1MXktleqsA%3D%3D
    • (2009) DNA Repair (Amst) , vol.8 , pp. 162-169
    • Wasko, B.M.1    Holland, C.L.2    Resnick, M.A.3    Lewis, L.K.4
  • 60
    • 0033008194 scopus 로고    scopus 로고
    • Homology search and choice of homologous partner during mitotic recombination
    • 10330153 1:CAS:528:DyaK1MXjt1yjur0%3D
    • O Inbar M Kupiec 1999 Homology search and choice of homologous partner during mitotic recombination Mol Cell Biol 19 4134 4142 10330153 1:CAS:528:DyaK1MXjt1yjur0%3D
    • (1999) Mol Cell Biol , vol.19 , pp. 4134-4142
    • Inbar, O.1    Kupiec, M.2
  • 61
    • 59249107930 scopus 로고    scopus 로고
    • Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair
    • 19165339
    • ME Budd JL Campbell 2009 Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair PLoS ONE 4 e4267 19165339
    • (2009) PLoS ONE , vol.4 , pp. 4267
    • Budd, M.E.1    Campbell, J.L.2
  • 62
    • 0026530911 scopus 로고
    • Characterization of double-strand break-induced recombination: Homology requirements and single-stranded DNA formation
    • 1732731 1:CAS:528:DyaK3sXitVKksrg%3D
    • N Sugawara JE Haber 1992 Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation Mol Cell Biol 12 563 575 1732731 1:CAS:528:DyaK3sXitVKksrg%3D
    • (1992) Mol Cell Biol , vol.12 , pp. 563-575
    • Sugawara, N.1    Haber, J.E.2
  • 63
    • 1142265873 scopus 로고    scopus 로고
    • Recombination: Holliday junction resolution and crossover formation
    • 14738748 1:CAS:528:DC%2BD2cXnvV2jsA%3D%3D
    • WD Heyer 2004 Recombination: Holliday junction resolution and crossover formation Curr Biol 14 R56 R58 14738748 1:CAS:528:DC%2BD2cXnvV2jsA%3D%3D
    • (2004) Curr Biol , vol.14
    • Heyer, W.D.1
  • 65
    • 0035900652 scopus 로고    scopus 로고
    • Mus81-Eme1 are essential components of a Holliday junction resolvase
    • 11719193 1:CAS:528:DC%2BD3MXovVCntr4%3D
    • MN Boddy PH Gaillard WH McDonald P Shanahan JR Yates 3rd P Russell 2001 Mus81-Eme1 are essential components of a Holliday junction resolvase Cell 107 537 548 11719193 1:CAS:528:DC%2BD3MXovVCntr4%3D
    • (2001) Cell , vol.107 , pp. 537-548
    • Boddy, M.N.1    Gaillard, P.H.2    McDonald, W.H.3    Shanahan, P.4    Yates III, J.R.5    Russell, P.6
  • 66
    • 34247251492 scopus 로고    scopus 로고
    • Mus81 cleavage of Holliday junctions: A failsafe for processing meiotic recombination intermediates?
    • 17363897 1:CAS:528:DC%2BD2sXjslOmtbc%3D
    • LJ Gaskell F Osman RJ Gilbert MC Whitby 2007 Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates? EMBO J 26 1891 1901 17363897 1:CAS:528:DC%2BD2sXjslOmtbc%3D
    • (2007) EMBO J , vol.26 , pp. 1891-1901
    • Gaskell, L.J.1    Osman, F.2    Gilbert, R.J.3    Whitby, M.C.4
  • 67
    • 0035886690 scopus 로고    scopus 로고
    • Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease
    • 11641278 1:CAS:528:DC%2BD3MXnvVWksbo%3D
    • V Kaliraman JR Mullen WM Fricke SA Bastin-Shanower SJ Brill 2001 Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease Genes Dev 15 2730 2740 11641278 1:CAS:528:DC%2BD3MXnvVWksbo%3D
    • (2001) Genes Dev , vol.15 , pp. 2730-2740
    • Kaliraman, V.1    Mullen, J.R.2    Fricke, W.M.3    Bastin-Shanower, S.A.4    Brill, S.J.5
  • 68
    • 48349139797 scopus 로고    scopus 로고
    • RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination
    • 18691965 1:CAS:528:DC%2BD1cXhtVSrsrjJ
    • SD Oh JP Lao AF Taylor GR Smith N Hunter 2008 RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination Mol Cell 31 324 336 18691965 1:CAS:528:DC%2BD1cXhtVSrsrjJ
    • (2008) Mol Cell , vol.31 , pp. 324-336
    • Oh, S.D.1    Lao, J.P.2    Taylor, A.F.3    Smith, G.R.4    Hunter, N.5
  • 69
    • 48349141924 scopus 로고    scopus 로고
    • Mus81/Mms4 endonuclease and Sgs1 helicase collaborate to ensure proper recombination intermediate metabolism during meiosis
    • 18691964 1:CAS:528:DC%2BD1cXhtVSrsrjI
    • L Jessop M Lichten 2008 Mus81/Mms4 endonuclease and Sgs1 helicase collaborate to ensure proper recombination intermediate metabolism during meiosis Mol Cell 31 313 323 18691964 1:CAS:528:DC%2BD1cXhtVSrsrjI
    • (2008) Mol Cell , vol.31 , pp. 313-323
    • Jessop, L.1    Lichten, M.2
  • 70
    • 0037854709 scopus 로고    scopus 로고
    • The Mus81/Mms4 endonuclease acts independently of double-Holliday junction resolution to promote a distinct subset of crossovers during meiosis in budding yeast
    • T de los Santos N Hunter C Lee B Larkin J Loidl NM Hollingsworth 2003 The Mus81/Mms4 endonuclease acts independently of double-Holliday junction resolution to promote a distinct subset of crossovers during meiosis in budding yeast Genetics 164 81 94
    • (2003) Genetics , vol.164 , pp. 81-94
    • De Los Santos, T.1    Hunter, N.2    Lee, C.3    Larkin, B.4    Loidl, J.5    Hollingsworth, N.M.6
  • 71
    • 0035977119 scopus 로고    scopus 로고
    • The fuss about Mus81
    • 11733053 1:CAS:528:DC%2BD3MXptVaqsbk%3D
    • JE Haber WD Heyer 2001 The fuss about Mus81 Cell 107 551 554 11733053 1:CAS:528:DC%2BD3MXptVaqsbk%3D
    • (2001) Cell , vol.107 , pp. 551-554
    • Haber, J.E.1    Heyer, W.D.2
  • 72
    • 56749119855 scopus 로고    scopus 로고
    • Identification of Holliday junction resolvases from humans and yeast
    • 19020614 1:CAS:528:DC%2BD1cXhsVSjsLvE
    • SC Ip U Rass MG Blanco HR Flynn JM Skehel SC West 2008 Identification of Holliday junction resolvases from humans and yeast Nature 456 357 361 19020614 1:CAS:528:DC%2BD1cXhsVSjsLvE
    • (2008) Nature , vol.456 , pp. 357-361
    • Ip, S.C.1    Rass, U.2    Blanco, M.G.3    Flynn, H.R.4    Skehel, J.M.5    West, S.C.6
  • 73
    • 0345447604 scopus 로고    scopus 로고
    • Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast
    • 14622595 1:CAS:528:DC%2BD3sXpt1Oru7g%3D
    • G Ira A Malkova G Liberi M Foiani JE Haber 2003 Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast Cell 115 401 411 14622595 1:CAS:528:DC%2BD3sXpt1Oru7g%3D
    • (2003) Cell , vol.115 , pp. 401-411
    • Ira, G.1    Malkova, A.2    Liberi, G.3    Foiani, M.4    Haber, J.E.5
  • 74
    • 0347987856 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase suppresses crossing over during homologous recombination
    • 14685245 1:CAS:528:DC%2BD3sXpvVGmtbs%3D
    • L Wu ID Hickson 2003 The Bloom's syndrome helicase suppresses crossing over during homologous recombination Nature 426 870 874 14685245 1:CAS:528:DC%2BD3sXpvVGmtbs%3D
    • (2003) Nature , vol.426 , pp. 870-874
    • Wu, L.1    Hickson, I.D.2
  • 75
    • 35348986443 scopus 로고    scopus 로고
    • Binding and activation of DNA topoisomerase III by the Rmi1 subunit
    • 17693398 1:CAS:528:DC%2BD2sXhtVOmtbjK
    • CF Chen SJ Brill 2007 Binding and activation of DNA topoisomerase III by the Rmi1 subunit J Biol Chem 282 28971 28979 17693398 1:CAS:528: DC%2BD2sXhtVOmtbjK
    • (2007) J Biol Chem , vol.282 , pp. 28971-28979
    • Chen, C.F.1    Brill, S.J.2
  • 76
    • 0028859379 scopus 로고
    • Somatic intragenic recombination within the mutated locus BLM can correct the high sister-chromatid exchange phenotype of Bloom syndrome cells
    • 7485150 1:CAS:528:DyaK2MXpslSgs74%3D
    • NA Ellis DJ Lennon M Proytcheva B Alhadeff EE Henderson J German 1995 Somatic intragenic recombination within the mutated locus BLM can correct the high sister-chromatid exchange phenotype of Bloom syndrome cells Am J Hum Genet 57 1019 1027 7485150 1:CAS:528:DyaK2MXpslSgs74%3D
    • (1995) Am J Hum Genet , vol.57 , pp. 1019-1027
    • Ellis, N.A.1    Lennon, D.J.2    Proytcheva, M.3    Alhadeff, B.4    Henderson, E.E.5    German, J.6
  • 77
    • 11244250729 scopus 로고    scopus 로고
    • Examination of the roles of Sgs1 and Srs2 helicases in the enforcement of recombination fidelity in Saccharomyces cerevisiae
    • 15611162 1:CAS:528:DC%2BD2MXhtVOqu70%3D
    • RM Spell S Jinks-Robertson 2004 Examination of the roles of Sgs1 and Srs2 helicases in the enforcement of recombination fidelity in Saccharomyces cerevisiae Genetics 168 1855 1865 15611162 1:CAS:528:DC%2BD2MXhtVOqu70%3D
    • (2004) Genetics , vol.168 , pp. 1855-1865
    • Spell, R.M.1    Jinks-Robertson, S.2
  • 78
    • 3042546122 scopus 로고    scopus 로고
    • Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1
    • 15199178 1:CAS:528:DC%2BD2cXltlKjsrk%3D
    • N Sugawara T Goldfarb B Studamire E Alani JE Haber 2004 Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1 Proc Natl Acad Sci USA 101 9315 9320 15199178 1:CAS:528:DC%2BD2cXltlKjsrk%3D
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9315-9320
    • Sugawara, N.1    Goldfarb, T.2    Studamire, B.3    Alani, E.4    Haber, J.E.5
  • 79
    • 0035158640 scopus 로고    scopus 로고
    • SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination
    • 11138010 1:CAS:528:DC%2BD3MXis1yrtA%3D%3D
    • K Myung A Datta C Chen RD Kolodner 2001 SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination Nat Genet 27 113 116 11138010 1:CAS:528: DC%2BD3MXis1yrtA%3D%3D
    • (2001) Nat Genet , vol.27 , pp. 113-116
    • Myung, K.1    Datta, A.2    Chen, C.3    Kolodner, R.D.4
  • 80
    • 56449090762 scopus 로고    scopus 로고
    • Rising from the RecQ-age: The role of human RecQ helicases in genome maintenance
    • 18926708 1:CAS:528:DC%2BD1cXhsVGgtr3F
    • VA Bohr 2008 Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance Trends Biochem Sci 33 609 620 18926708 1:CAS:528:DC%2BD1cXhsVGgtr3F
    • (2008) Trends Biochem Sci , vol.33 , pp. 609-620
    • Bohr, V.A.1
  • 81
    • 33746715608 scopus 로고    scopus 로고
    • Rad54 protein promotes branch migration of Holliday junctions
    • 16862129 1:CAS:528:DC%2BD28Xnsl2js7o%3D
    • DV Bugreev OM Mazina AV Mazin 2006 Rad54 protein promotes branch migration of Holliday junctions Nature 442 590 593 16862129 1:CAS:528: DC%2BD28Xnsl2js7o%3D
    • (2006) Nature , vol.442 , pp. 590-593
    • Bugreev, D.V.1    Mazina, O.M.2    Mazin, A.V.3
  • 82
    • 38349050087 scopus 로고    scopus 로고
    • The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks
    • 18206976 1:CAS:528:DC%2BD1cXhtlWjtLY%3D
    • K Gari C Decaillet AZ Stasiak A Stasiak A Constantinou 2008 The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks Mol Cell 29 141 148 18206976 1:CAS:528:DC%2BD1cXhtlWjtLY%3D
    • (2008) Mol Cell , vol.29 , pp. 141-148
    • Gari, K.1    Decaillet, C.2    Stasiak, A.Z.3    Stasiak, A.4    Constantinou, A.5
  • 83
    • 58149494717 scopus 로고    scopus 로고
    • Yeast Mph1 helicase dissociates Rad51-made D-loops: Implications for crossover control in mitotic recombination
    • 19136626 1:CAS:528:DC%2BD1MXptFWltA%3D%3D
    • R Prakash D Satory E Dray A Papusha J Scheller W Kramer L Krejci H Klein JE Haber P Sung G Ira 2009 Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination Genes Dev 23 67 79 19136626 1:CAS:528:DC%2BD1MXptFWltA%3D%3D
    • (2009) Genes Dev , vol.23 , pp. 67-79
    • Prakash, R.1    Satory, D.2    Dray, E.3    Papusha, A.4    Scheller, J.5    Kramer, W.6    Krejci, L.7    Klein, H.8    Haber, J.E.9    Sung, P.10    Ira, G.11
  • 84
    • 53149087431 scopus 로고    scopus 로고
    • The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair
    • 18851838 1:CAS:528:DC%2BD1cXht1GksLzL
    • W Sun S Nandi F Osman JS Ahn J Jakovleska A Lorenz MC Whitby 2008 The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair Mol Cell 32 118 128 18851838 1:CAS:528:DC%2BD1cXht1GksLzL
    • (2008) Mol Cell , vol.32 , pp. 118-128
    • Sun, W.1    Nandi, S.2    Osman, F.3    Ahn, J.S.4    Jakovleska, J.5    Lorenz, A.6    Whitby, M.C.7
  • 85
    • 46249091062 scopus 로고    scopus 로고
    • Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination
    • 18591428 1:CAS:528:DC%2BD1cXotF2itrc%3D
    • S Banerjee S Smith JH Oum HJ Liaw JY Hwang N Sikdar A Motegi SE Lee K Myung 2008 Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination J Cell Biol 181 1083 1093 18591428 1:CAS:528:DC%2BD1cXotF2itrc%3D
    • (2008) J Cell Biol , vol.181 , pp. 1083-1093
    • Banerjee, S.1    Smith, S.2    Oum, J.H.3    Liaw, H.J.4    Hwang, J.Y.5    Sikdar, N.6    Motegi, A.7    Lee, S.E.8    Myung, K.9
  • 86
    • 23344449102 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype
    • 16055731 1:CAS:528:DC%2BD2MXhtVejs7%2FM
    • CD Putnam V Pennaneach RD Kolodner 2005 Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype Mol Cell Biol 25 7226 7238 16055731 1:CAS:528:DC%2BD2MXhtVejs7%2FM
    • (2005) Mol Cell Biol , vol.25 , pp. 7226-7238
    • Putnam, C.D.1    Pennaneach, V.2    Kolodner, R.D.3
  • 87
    • 0034621854 scopus 로고    scopus 로고
    • Frequent chromosomal translocations induced by DNA double-strand breaks
    • 10864328 1:CAS:528:DC%2BD3cXktlGnsrY%3D
    • C Richardson M Jasin 2000 Frequent chromosomal translocations induced by DNA double-strand breaks Nature 405 697 700 10864328 1:CAS:528: DC%2BD3cXktlGnsrY%3D
    • (2000) Nature , vol.405 , pp. 697-700
    • Richardson, C.1    Jasin, M.2
  • 88
    • 47949092912 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations
    • 18650924 1:CAS:528:DC%2BD1cXovV2mtL8%3D
    • K Lee Y Zhang SE Lee 2008 Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations Nature 454 543 546 18650924 1:CAS:528:DC%2BD1cXovV2mtL8%3D
    • (2008) Nature , vol.454 , pp. 543-546
    • Lee, K.1    Zhang, Y.2    Lee, S.E.3
  • 89
    • 34547589577 scopus 로고    scopus 로고
    • Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70
    • 17643113 1:CAS:528:DC%2BD2sXpt1OlsL4%3D
    • DM Weinstock E Brunet M Jasin 2007 Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70 Nat Cell Biol 9 978 981 17643113 1:CAS:528:DC%2BD2sXpt1OlsL4%3D
    • (2007) Nat Cell Biol , vol.9 , pp. 978-981
    • Weinstock, D.M.1    Brunet, E.2    Jasin, M.3
  • 90
    • 39449112668 scopus 로고    scopus 로고
    • Mechanistic flexibility as a conserved theme across 3 billion years of nonhomologous DNA end-joining
    • 18281457 1:CAS:528:DC%2BD1cXivVaisbY%3D
    • J Gu MR Lieber 2008 Mechanistic flexibility as a conserved theme across 3 billion years of nonhomologous DNA end-joining Genes Dev 22 411 415 18281457 1:CAS:528:DC%2BD1cXivVaisbY%3D
    • (2008) Genes Dev , vol.22 , pp. 411-415
    • Gu, J.1    Lieber, M.R.2
  • 91
    • 1542287213 scopus 로고    scopus 로고
    • A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex
    • 14999286 1:CAS:528:DC%2BD2cXhslCns7c%3D
    • SC Raghavan PC Swanson X Wu CL Hsieh MR Lieber 2004 A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex Nature 428 88 93 14999286 1:CAS:528:DC%2BD2cXhslCns7c%3D
    • (2004) Nature , vol.428 , pp. 88-93
    • Raghavan, S.C.1    Swanson, P.C.2    Wu, X.3    Hsieh, C.L.4    Lieber, M.R.5
  • 93
    • 57349185631 scopus 로고    scopus 로고
    • Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity
    • 19070581 1:CAS:528:DC%2BD1MXnslyn
    • AG Tsai H Lu SC Raghavan M Muschen CL Hsieh MR Lieber 2008 Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity Cell 135 1130 1142 19070581 1:CAS:528: DC%2BD1MXnslyn
    • (2008) Cell , vol.135 , pp. 1130-1142
    • Tsai, A.G.1    Lu, H.2    Raghavan, S.C.3    Muschen, M.4    Hsieh, C.L.5    Lieber, M.R.6
  • 94
    • 10344240414 scopus 로고    scopus 로고
    • Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex
    • 15589152 1:CAS:528:DC%2BD2cXhtVKrtbrL
    • K Lobachev E Vitriol J Stemple MA Resnick K Bloom 2004 Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex Curr Biol 14 2107 2112 15589152 1:CAS:528:DC%2BD2cXhtVKrtbrL
    • (2004) Curr Biol , vol.14 , pp. 2107-2112
    • Lobachev, K.1    Vitriol, E.2    Stemple, J.3    Resnick, M.A.4    Bloom, K.5
  • 95
    • 10344225665 scopus 로고    scopus 로고
    • DNA breaks promote genomic instability by impeding proper chromosome segregation
    • 15589151 1:CAS:528:DC%2BD2cXhtVKrtbrK
    • JA Kaye JA Melo SK Cheung MB Vaze JE Haber DP Toczyski 2004 DNA breaks promote genomic instability by impeding proper chromosome segregation Curr Biol 14 2096 2106 15589151 1:CAS:528:DC%2BD2cXhtVKrtbrK
    • (2004) Curr Biol , vol.14 , pp. 2096-2106
    • Kaye, J.A.1    Melo, J.A.2    Cheung, S.K.3    Vaze, M.B.4    Haber, J.E.5    Toczyski, D.P.6
  • 96
    • 62549130381 scopus 로고    scopus 로고
    • Live cell microscopy analysis of radiation-induced DNA double-strand break motion
    • 19221031 1:CAS:528:DC%2BD1MXivF2jsr4%3D
    • B Jakob J Splinter M Durante G Taucher-Scholz 2009 Live cell microscopy analysis of radiation-induced DNA double-strand break motion Proc Natl Acad Sci USA 106 9 3172 3177 19221031 1:CAS:528:DC%2BD1MXivF2jsr4%3D
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.9 , pp. 3172-3177
    • Jakob, B.1    Splinter, J.2    Durante, M.3    Taucher-Scholz, G.4
  • 97
    • 0032562595 scopus 로고    scopus 로고
    • In situ visualization of DNA double-strand break repair in human fibroblasts
    • 9554850 1:CAS:528:DyaK1cXjtVaiu78%3D
    • BE Nelms RS Maser JF MacKay MG Lagally JH Petrini 1998 In situ visualization of DNA double-strand break repair in human fibroblasts Science 280 590 592 9554850 1:CAS:528:DyaK1cXjtVaiu78%3D
    • (1998) Science , vol.280 , pp. 590-592
    • Nelms, B.E.1    Maser, R.S.2    MacKay, J.F.3    Lagally, M.G.4    Petrini, J.H.5
  • 99
    • 33748144349 scopus 로고    scopus 로고
    • Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations
    • 1:CAS:528:DC%2BD28XptFSrsbs%3D
    • S Franco FW Alt JP Manis 2006 Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations DNA Repair (Amst) 5 1030 1041 1:CAS:528:DC%2BD28XptFSrsbs%3D
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1030-1041
    • Franco, S.1    Alt, F.W.2    Manis, J.P.3
  • 100
    • 33646831821 scopus 로고    scopus 로고
    • Telomeres, chromosome instability and cancer
    • 16682448 1:CAS:528:DC%2BD28Xks1Slsr0%3D
    • SM Bailey JP Murnane 2006 Telomeres, chromosome instability and cancer Nucleic Acids Res 34 2408 2417 16682448 1:CAS:528:DC%2BD28Xks1Slsr0%3D
    • (2006) Nucleic Acids Res , vol.34 , pp. 2408-2417
    • Bailey, S.M.1    Murnane, J.P.2
  • 101
    • 57049132043 scopus 로고    scopus 로고
    • 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
    • 18931659 1:CAS:528:DC%2BD1cXhsVegur7M
    • N Dimitrova YC Chen DL Spector T de Lange 2008 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility Nature 456 524 528 18931659 1:CAS:528:DC%2BD1cXhsVegur7M
    • (2008) Nature , vol.456 , pp. 524-528
    • Dimitrova, N.1    Chen, Y.C.2    Spector, D.L.3    De Lange, T.4
  • 103
    • 34047102946 scopus 로고    scopus 로고
    • Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks
    • 17347674 1:CAS:528:DC%2BD2sXjs1yqtLs%3D
    • D Mantiero M Clerici G Lucchini MP Longhese 2007 Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks EMBO Rep 8 380 387 17347674 1:CAS:528:DC%2BD2sXjs1yqtLs%3D
    • (2007) EMBO Rep , vol.8 , pp. 380-387
    • Mantiero, D.1    Clerici, M.2    Lucchini, G.3    Longhese, M.P.4
  • 105
    • 53149091313 scopus 로고    scopus 로고
    • Aberrant V(D)J recombination in ataxia telangiectasia mutated-deficient lymphocytes is dependent on nonhomologous DNA end joining
    • 18684952 1:CAS:528:DC%2BD1cXptlOjsr0%3D
    • AL Bredemeyer CY Huang LM Walker CH Bassing BP Sleckman 2008 Aberrant V(D)J recombination in ataxia telangiectasia mutated-deficient lymphocytes is dependent on nonhomologous DNA end joining J Immunol 181 2620 2625 18684952 1:CAS:528:DC%2BD1cXptlOjsr0%3D
    • (2008) J Immunol , vol.181 , pp. 2620-2625
    • Bredemeyer, A.L.1    Huang, C.Y.2    Walker, L.M.3    Bassing, C.H.4    Sleckman, B.P.5
  • 107
    • 8644238314 scopus 로고    scopus 로고
    • ATM is required for efficient recombination between immunoglobulin switch regions
    • 15520243 1:CAS:528:DC%2BD2cXpsFCgs70%3D
    • B Reina-San-Martin HT Chen A Nussenzweig MC Nussenzweig 2004 ATM is required for efficient recombination between immunoglobulin switch regions J Exp Med 200 1103 1110 15520243 1:CAS:528:DC%2BD2cXpsFCgs70%3D
    • (2004) J Exp Med , vol.200 , pp. 1103-1110
    • Reina-San-Martin, B.1    Chen, H.T.2    Nussenzweig, A.3    Nussenzweig, M.C.4
  • 108
    • 2442706035 scopus 로고    scopus 로고
    • H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity
    • 14712078 1:CAS:528:DC%2BD2cXisFGmsr8%3D
    • CH Bassing FW Alt 2004 H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity Cell Cycle 3 149 153 14712078 1:CAS:528:DC%2BD2cXisFGmsr8%3D
    • (2004) Cell Cycle , vol.3 , pp. 149-153
    • Bassing, C.H.1    Alt, F.W.2
  • 111
    • 0037716757 scopus 로고    scopus 로고
    • Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining
    • 12769860 1:CAS:528:DC%2BD3sXksVOjtLY%3D
    • SW Chan EH Blackburn 2003 Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining Mol Cell 11 1379 1387 12769860 1:CAS:528: DC%2BD3sXksVOjtLY%3D
    • (2003) Mol Cell , vol.11 , pp. 1379-1387
    • Chan, S.W.1    Blackburn, E.H.2
  • 112
    • 0033605145 scopus 로고    scopus 로고
    • P53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
    • 10037601 1:CAS:528:DyaK1MXhs1CjsLY%3D
    • J Karlseder D Broccoli Y Dai S Hardy T de Lange 1999 p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 Science 283 1321 1325 10037601 1:CAS:528:DyaK1MXhs1CjsLY%3D
    • (1999) Science , vol.283 , pp. 1321-1325
    • Karlseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    De Lange, T.5
  • 113
    • 5144225797 scopus 로고    scopus 로고
    • DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining
    • 15466592 1:CAS:528:DC%2BD2cXotlWmur4%3D
    • J Bentley CP Diggle P Harnden MA Knowles AE Kiltie 2004 DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining Nucleic Acids Res 32 5249 5259 15466592 1:CAS:528:DC%2BD2cXotlWmur4%3D
    • (2004) Nucleic Acids Res , vol.32 , pp. 5249-5259
    • Bentley, J.1    Diggle, C.P.2    Harnden, P.3    Knowles, M.A.4    Kiltie, A.E.5
  • 114
    • 51649128895 scopus 로고    scopus 로고
    • Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: Consequences for the repair of DNA double-strand breaks
    • 18524993 1:CAS:528:DC%2BD1cXpvVOktbw%3D
    • A Sallmyr AE Tomkinson FV Rassool 2008 Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks Blood 112 1413 1423 18524993 1:CAS:528:DC%2BD1cXpvVOktbw%3D
    • (2008) Blood , vol.112 , pp. 1413-1423
    • Sallmyr, A.1    Tomkinson, A.E.2    Rassool, F.V.3
  • 115
    • 46149118183 scopus 로고    scopus 로고
    • The kleisin subunit of cohesin dictates damage-induced cohesion
    • 18614046 1:CAS:528:DC%2BD1cXovFWnsr8%3D
    • JM Heidinger-Pauli E Unal V Guacci D Koshland 2008 The kleisin subunit of cohesin dictates damage-induced cohesion Mol Cell 31 47 56 18614046 1:CAS:528:DC%2BD1cXovFWnsr8%3D
    • (2008) Mol Cell , vol.31 , pp. 47-56
    • Heidinger-Pauli, J.M.1    Unal, E.2    Guacci, V.3    Koshland, D.4
  • 116
    • 48149093617 scopus 로고    scopus 로고
    • Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications
    • 1:CAS:528:DC%2BD1cXpsVGgsrw%3D
    • JY Hwang S Smith A Ceschia J Torres-Rosell L Aragon K Myung 2008 Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications DNA Repair (Amst) 7 1426 1436 1:CAS:528: DC%2BD1cXpsVGgsrw%3D
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1426-1436
    • Hwang, J.Y.1    Smith, S.2    Ceschia, A.3    Torres-Rosell, J.4    Aragon, L.5    Myung, K.6
  • 117
    • 16244368497 scopus 로고    scopus 로고
    • Suppression of gross chromosomal rearrangements by the multiple functions of the Mre11-Rad50-Xrs2 complex in Saccharomyces cerevisiae
    • DOI 10.1016/j.dnarep.2005.01.004
    • S Smith A Gupta RD Kolodner K Myung 2005 Suppression of gross chromosomal rearrangements by the multiple functions of the Mre11-Rad50-Xrs2 complex in Saccharomyces cerevisiae DNA Repair (Amst) 4 606 617 1:CAS:528: DC%2BD2MXjt1Kit7k%3D (Pubitemid 40462048)
    • (2005) DNA Repair , vol.4 , Issue.5 , pp. 606-617
    • Smith, S.1    Gupta, A.2    Kolodner, R.D.3    Myung, K.4
  • 118
    • 36248942617 scopus 로고    scopus 로고
    • Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
    • 18042458 1:CAS:528:DC%2BD2sXhsVGmurvL
    • BM Lengsfeld AJ Rattray V Bhaskara R Ghirlando TT Paull 2007 Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex Mol Cell 28 638 651 18042458 1:CAS:528:DC%2BD2sXhsVGmurvL
    • (2007) Mol Cell , vol.28 , pp. 638-651
    • Lengsfeld, B.M.1    Rattray, A.J.2    Bhaskara, V.3    Ghirlando, R.4    Paull, T.T.5
  • 120
    • 35649023709 scopus 로고    scopus 로고
    • The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles
    • 17724085 1:CAS:528:DC%2BD2sXht1Gltr3F
    • I Chiolo M Saponaro A Baryshnikova JH Kim YS Seo G Liberi 2007 The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles Mol Cell Biol 27 7439 7450 17724085 1:CAS:528: DC%2BD2sXht1Gltr3F
    • (2007) Mol Cell Biol , vol.27 , pp. 7439-7450
    • Chiolo, I.1    Saponaro, M.2    Baryshnikova, A.3    Kim, J.H.4    Seo, Y.S.5    Liberi, G.6
  • 121
    • 0033996037 scopus 로고    scopus 로고
    • Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange
    • 10757799 1:CAS:528:DC%2BD3cXivFSkurc%3D
    • ML Dronkert HB Beverloo RD Johnson JH Hoeijmakers M Jasin R Kanaar 2000 Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange Mol Cell Biol 20 3147 3156 10757799 1:CAS:528:DC%2BD3cXivFSkurc%3D
    • (2000) Mol Cell Biol , vol.20 , pp. 3147-3156
    • Dronkert, M.L.1    Beverloo, H.B.2    Johnson, R.D.3    Hoeijmakers, J.H.4    Jasin, M.5    Kanaar, R.6
  • 122
    • 0141707817 scopus 로고    scopus 로고
    • Generating crossovers by resolution of nicked Holliday junctions: A role for Mus81-Eme1 in meiosis
    • 14527420 1:CAS:528:DC%2BD3sXnvFGrt7k%3D
    • F Osman J Dixon CL Doe MC Whitby 2003 Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis Mol Cell 12 761 774 14527420 1:CAS:528:DC%2BD3sXnvFGrt7k%3D
    • (2003) Mol Cell , vol.12 , pp. 761-774
    • Osman, F.1    Dixon, J.2    Doe, C.L.3    Whitby, M.C.4
  • 123
    • 0742305344 scopus 로고    scopus 로고
    • RNA interference inhibition of Mus81 reduces mitotic recombination in human cells
    • 14617801 1:CAS:528:DC%2BD2cXhtlGmtbg%3D
    • V Blais H Gao CA Elwell MN Boddy PH Gaillard P Russell CH McGowan 2004 RNA interference inhibition of Mus81 reduces mitotic recombination in human cells Mol Biol Cell 15 552 562 14617801 1:CAS:528:DC%2BD2cXhtlGmtbg%3D
    • (2004) Mol Biol Cell , vol.15 , pp. 552-562
    • Blais, V.1    Gao, H.2    Elwell, C.A.3    Boddy, M.N.4    Gaillard, P.H.5    Russell, P.6    McGowan, C.H.7
  • 124
    • 0037468192 scopus 로고    scopus 로고
    • MDC1 is a mediator of the mammalian DNA damage checkpoint
    • 12607005 1:CAS:528:DC%2BD3sXhsVKgtbo%3D
    • GS Stewart B Wang CR Bignell AM Taylor SJ Elledge 2003 MDC1 is a mediator of the mammalian DNA damage checkpoint Nature 421 961 966 12607005 1:CAS:528:DC%2BD3sXhsVKgtbo%3D
    • (2003) Nature , vol.421 , pp. 961-966
    • Stewart, G.S.1    Wang, B.2    Bignell, C.R.3    Taylor, A.M.4    Elledge, S.J.5
  • 126
    • 0032860479 scopus 로고    scopus 로고
    • Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
    • 10471504 1:CAS:528:DyaK1MXlvFWhtr8%3D
    • C Chen RD Kolodner 1999 Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants Nat Genet 23 81 85 10471504 1:CAS:528:DyaK1MXlvFWhtr8%3D
    • (1999) Nat Genet , vol.23 , pp. 81-85
    • Chen, C.1    Kolodner, R.D.2
  • 127
    • 0032109778 scopus 로고    scopus 로고
    • Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair
    • 9702187 1:CAS:528:DyaK1cXltVelsrs%3D
    • C Chen K Umezu RD Kolodner 1998 Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair Mol Cell 2 9 22 9702187 1:CAS:528:DyaK1cXltVelsrs%3D
    • (1998) Mol Cell , vol.2 , pp. 9-22
    • Chen, C.1    Umezu, K.2    Kolodner, R.D.3


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