메뉴 건너뛰기




Volumn 22, Issue 4, 2008, Pages 411-415

Mechanistic flexibility as a conserved theme across 3 billion years of nonhomologous DNA end-joining

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE ALPHA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

EID: 39449112668     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1646608     Document Type: Review
Times cited : (36)

References (39)
  • 1
    • 39449129496 scopus 로고    scopus 로고
    • The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends
    • this issue, doi: 10.1101/gad.1631908
    • Aniukwu, J., Glickman, M.S., and Shuman, S. 2008. The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends. Genes & Dev. (this issue), doi: 10.1101/gad.1631908.
    • (2008) Genes & Dev
    • Aniukwu, J.1    Glickman, M.S.2    Shuman, S.3
  • 2
    • 0034889360 scopus 로고    scopus 로고
    • Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system
    • Aravind, L. and Koonin, E.V. 2001. Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system. Genome Res. 11: 1365-1374.
    • (2001) Genome Res , vol.11 , pp. 1365-1374
    • Aravind, L.1    Koonin, E.V.2
  • 3
    • 33745997776 scopus 로고    scopus 로고
    • Nonoverlapping functions of DNA polymerases μ, λ, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo
    • Bertocci, B., De Smet, A., Weill, J.C., and Reynaud, C.A. 2006. Nonoverlapping functions of DNA polymerases μ, λ, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo. Immunity 25: 31-41.
    • (2006) Immunity , vol.25 , pp. 31-41
    • Bertocci, B.1    De Smet, A.2    Weill, J.C.3    Reynaud, C.A.4
  • 5
    • 0031214080 scopus 로고    scopus 로고
    • Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV
    • Critchlow, S., Bowater, R., and Jackson, S.P. 1997. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr. Biol. 7: 588-598.
    • (1997) Curr. Biol , vol.7 , pp. 588-598
    • Critchlow, S.1    Bowater, R.2    Jackson, S.P.3
  • 6
    • 0347927261 scopus 로고    scopus 로고
    • The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku
    • d'Adda di Fagagna, F., Weller, G.R., Doherty, A.J., and Jackson, S.P. 2003. The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku. EMBO Rep. 4: 47-52.
    • (2003) EMBO Rep , vol.4 , pp. 47-52
    • d'Adda di Fagagna, F.1    Weller, G.R.2    Doherty, A.J.3    Jackson, S.P.4
  • 8
    • 0035816444 scopus 로고    scopus 로고
    • Identification of bacterial homologues of the Ku DNA repair proteins
    • Doherty, A.J., Jackson, S.P., and Weller, G.R. 2001. Identification of bacterial homologues of the Ku DNA repair proteins. FEBS Lett. 500: 186-188.
    • (2001) FEBS Lett , vol.500 , pp. 186-188
    • Doherty, A.J.1    Jackson, S.P.2    Weller, G.R.3
  • 9
    • 2442717521 scopus 로고    scopus 로고
    • Biochemical and genetic analysis of the four DNA ligases of mycobacteria
    • Gong, C., Martins, A., Bongiorno, P., Glickman, M., and Shuman, S. 2004. Biochemical and genetic analysis of the four DNA ligases of mycobacteria. J. Biol. Chem. 279: 20594-20606.
    • (2004) J. Biol. Chem , vol.279 , pp. 20594-20606
    • Gong, C.1    Martins, A.2    Bongiorno, P.3    Glickman, M.4    Shuman, S.5
  • 10
    • 18744380665 scopus 로고    scopus 로고
    • Mechanism of nonhomologous end-joining in mycobacteria: A low-fidelity repair system driven by Ku, ligase D and ligase C
    • Gong, C., Bongiorno, P., Martins, A., Stephanou, N.C., Zhu, H., Shuman, S., and Glickman, M.S. 2005. Mechanism of nonhomologous end-joining in mycobacteria: A low-fidelity repair system driven by Ku, ligase D and ligase C. Nat. Struct. Mol. Biol. 12: 304-312.
    • (2005) Nat. Struct. Mol. Biol , vol.12 , pp. 304-312
    • Gong, C.1    Bongiorno, P.2    Martins, A.3    Stephanou, N.C.4    Zhu, H.5    Shuman, S.6    Glickman, M.S.7
  • 11
    • 0030743386 scopus 로고    scopus 로고
    • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
    • Grawunder, U., Wilm, M., Wu, X., Kulesza, P., Wilson, T.E., Mann, M., and Lieber, M.R. 1997. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 388: 492-495.
    • (1997) Nature , vol.388 , pp. 492-495
    • Grawunder, U.1    Wilm, M.2    Wu, X.3    Kulesza, P.4    Wilson, T.E.5    Mann, M.6    Lieber, M.R.7
  • 12
    • 0032185230 scopus 로고    scopus 로고
    • DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes
    • Grawunder, U., Zimmer, D., Fugmann, S., Schwarz, K., and Lieber, M.R. 1998. DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. Mol. Cell 2: 477-484.
    • (1998) Mol. Cell , vol.2 , pp. 477-484
    • Grawunder, U.1    Zimmer, D.2    Fugmann, S.3    Schwarz, K.4    Lieber, M.R.5
  • 13
    • 33847193121 scopus 로고    scopus 로고
    • XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
    • Gu, J., Lu, H., Tippin, B., Shimazaki, N., Goodman, M.F., and Lieber, M.R. 2007a. XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps. EMBO J. 26: 1010-1023.
    • (2007) EMBO J , vol.26 , pp. 1010-1023
    • Gu, J.1    Lu, H.2    Tippin, B.3    Shimazaki, N.4    Goodman, M.F.5    Lieber, M.R.6
  • 14
    • 34848841930 scopus 로고    scopus 로고
    • Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: Influence of terminal DNA sequence
    • Gu, J., Lu, H., Tsai, A.G., Schwarz, K., and Lieber, M.R. 2007b. Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: Influence of terminal DNA sequence. Nucleic Acids Res. 35: 5755-5762.
    • (2007) Nucleic Acids Res , vol.35 , pp. 5755-5762
    • Gu, J.1    Lu, H.2    Tsai, A.G.3    Schwarz, K.4    Lieber, M.R.5
  • 15
    • 22444435033 scopus 로고    scopus 로고
    • Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: Structural insights and new members
    • Iyer, L.M., Koonin, E.V., Leipe, D.D., and Aravind, L. 2005. Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: Structural insights and new members. Nucleic Acids Res. 33: 3875-3896.
    • (2005) Nucleic Acids Res , vol.33 , pp. 3875-3896
    • Iyer, L.M.1    Koonin, E.V.2    Leipe, D.D.3    Aravind, L.4
  • 16
    • 38049115657 scopus 로고    scopus 로고
    • The mechanism of human nonhomologous DNA end joining
    • Lieber, M.R. 2007. The mechanism of human nonhomologous DNA end joining. J. Biol. Chem. 283: 1-5.
    • (2007) J. Biol. Chem , vol.283 , pp. 1-5
    • Lieber, M.R.1
  • 17
    • 0042839614 scopus 로고    scopus 로고
    • Mechanism and regulation of human non-homologous DNA end-joining
    • Lieber, M.R., Ma, Y., Pannicke, U., and Schwarz, K. 2003. Mechanism and regulation of human non-homologous DNA end-joining. Nat. Rev. Mol. Cell Biol. 4: 712-720.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 712-720
    • Lieber, M.R.1    Ma, Y.2    Pannicke, U.3    Schwarz, K.4
  • 18
    • 38049144085 scopus 로고    scopus 로고
    • Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: Relevance to cancer, aging, and the immune system
    • Lieber, M.R., Lu, H., Gu, J., and Schwarz, K. 2007. Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: Relevance to cancer, aging, and the immune system. Cell Res. 18: 125-133.
    • (2007) Cell Res , vol.18 , pp. 125-133
    • Lieber, M.R.1    Lu, H.2    Gu, J.3    Schwarz, K.4
  • 19
    • 0037155703 scopus 로고    scopus 로고
    • Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
    • Ma, Y., Pannicke, U., Schwarz, K., and Lieber, M.R. 2002. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108: 781-794.
    • (2002) Cell , vol.108 , pp. 781-794
    • Ma, Y.1    Pannicke, U.2    Schwarz, K.3    Lieber, M.R.4
  • 21
    • 34548534319 scopus 로고    scopus 로고
    • Expression of Mycobacterium tuberculosis Ku and Ligase D in Escherichia coli results in RecA and RecB-independent DNA end-joining at regions of microhomology
    • Malyarchuk, S., Wright, D., Castore, R., Klepper, E., Weiss, B., Doherty, A.J., and Harrison, L. 2007. Expression of Mycobacterium tuberculosis Ku and Ligase D in Escherichia coli results in RecA and RecB-independent DNA end-joining at regions of microhomology. DNA Repair (Amst.) 6: 1413-1424.
    • (2007) DNA Repair (Amst.) , vol.6 , pp. 1413-1424
    • Malyarchuk, S.1    Wright, D.2    Castore, R.3    Klepper, E.4    Weiss, B.5    Doherty, A.J.6    Harrison, L.7
  • 22
    • 0033119394 scopus 로고    scopus 로고
    • DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity
    • Modesti, M., Hesse, J.E., and Gellert, M. 1999. DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity. EMBO J. 18: 2008-2018.
    • (1999) EMBO J , vol.18 , pp. 2008-2018
    • Modesti, M.1    Hesse, J.E.2    Gellert, M.3
  • 23
    • 0037379215 scopus 로고    scopus 로고
    • Polymerase μ is a DNA-directed DNA/RNA polymerase
    • Nick McElhinny, S.A. and Ramsden, D.A. 2003. Polymerase μ is a DNA-directed DNA/RNA polymerase. Mol. Cell. Biol. 23: 2309-2315.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 2309-2315
    • Nick McElhinny, S.A.1    Ramsden, D.A.2
  • 24
    • 22544434934 scopus 로고    scopus 로고
    • Domain structure of a NHEJ DNA repair ligase from Mycobacterium tuberculosis
    • Pitcher, R.S., Tonkin, L.M., Green, A.J., and Doherty, A.J. 2005. Domain structure of a NHEJ DNA repair ligase from Mycobacterium tuberculosis. J. Mol. Biol. 351: 531-544.
    • (2005) J. Mol. Biol , vol.351 , pp. 531-544
    • Pitcher, R.S.1    Tonkin, L.M.2    Green, A.J.3    Doherty, A.J.4
  • 25
    • 35848960148 scopus 로고    scopus 로고
    • Nonhomologous end-joining in bacteria: A microbial perspective
    • Pitcher, R.S., Brissett, N.C., and Doherty, A.J. 2007a. Nonhomologous end-joining in bacteria: A microbial perspective. Annu. Rev. Microbiol. 61: 259-282.
    • (2007) Annu. Rev. Microbiol , vol.61 , pp. 259-282
    • Pitcher, R.S.1    Brissett, N.C.2    Doherty, A.J.3
  • 28
    • 0030749258 scopus 로고    scopus 로고
    • A newly identified DNA ligase of S. cerevisiae involved in RAD52-independent repair of DNA double-strand breaks
    • Schar, P., Herrmann, G., Daly, G., and Lindahl, T. 1997. A newly identified DNA ligase of S. cerevisiae involved in RAD52-independent repair of DNA double-strand breaks. Genes & Dev. 11: 1912-1924.
    • (1997) Genes & Dev , vol.11 , pp. 1912-1924
    • Schar, P.1    Herrmann, G.2    Daly, G.3    Lindahl, T.4
  • 29
    • 35348890199 scopus 로고    scopus 로고
    • Bacterial DNA repair by non-homologous end joining
    • Shuman, S. and Glickman, M.S. 2007. Bacterial DNA repair by non-homologous end joining. Nat. Rev. Microbiol. 5: 852-861.
    • (2007) Nat. Rev. Microbiol , vol.5 , pp. 852-861
    • Shuman, S.1    Glickman, M.S.2
  • 31
    • 34249938518 scopus 로고    scopus 로고
    • Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends
    • Tsai, C.J., Kim, S.A., and Chu, G. 2007. Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends. Proc. Natl. Acad. Sci. 104: 7851-7856.
    • (2007) Proc. Natl. Acad. Sci , vol.104 , pp. 7851-7856
    • Tsai, C.J.1    Kim, S.A.2    Chu, G.3
  • 32
    • 0035833552 scopus 로고    scopus 로고
    • Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
    • Walker, J.R., Corpina, R.A., and Goldberg, J. 2001. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature 412: 607-614.
    • (2001) Nature , vol.412 , pp. 607-614
    • Walker, J.R.1    Corpina, R.A.2    Goldberg, J.3
  • 33
    • 0035860377 scopus 로고    scopus 로고
    • A family of DNA repair ligases in bacteria?
    • Weller, G.R. and Doherty, A.J. 2001. A family of DNA repair ligases in bacteria? FEBS Lett. 505: 340-342.
    • (2001) FEBS Lett , vol.505 , pp. 340-342
    • Weller, G.R.1    Doherty, A.J.2
  • 35
    • 33748754050 scopus 로고    scopus 로고
    • Nucleotide misincorporation, 3′-mismatch extension, and responses to abasic sites and DNA adducts by the polymerase component of bacterial DNA ligase D
    • Yakovleva, L. and Shuman, S. 2006. Nucleotide misincorporation, 3′-mismatch extension, and responses to abasic sites and DNA adducts by the polymerase component of bacterial DNA ligase D. J. Biol. Chem. 281: 25026-25040.
    • (2006) J. Biol. Chem , vol.281 , pp. 25026-25040
    • Yakovleva, L.1    Shuman, S.2
  • 36
    • 22544469168 scopus 로고    scopus 로고
    • Novel 3′-ribonuclease and 3′-phosphatase activities of the bacterial non-homologous endjoining protein, DNA ligase D
    • Zhu, H. and Shuman, S. 2005a. Novel 3′-ribonuclease and 3′-phosphatase activities of the bacterial non-homologous endjoining protein, DNA ligase D. J. Biol. Chem. 280: 25973-25981.
    • (2005) J. Biol. Chem , vol.280 , pp. 25973-25981
    • Zhu, H.1    Shuman, S.2
  • 37
    • 12844250647 scopus 로고    scopus 로고
    • A primer-dependent polymerase function of Pseudomonas aeruginosa ATP-dependent DNA ligase (LigD)
    • Zhu, H. and Shuman, S. 2005b. A primer-dependent polymerase function of Pseudomonas aeruginosa ATP-dependent DNA ligase (LigD). J. Biol. Chem. 280: 418-427.
    • (2005) J. Biol. Chem , vol.280 , pp. 418-427
    • Zhu, H.1    Shuman, S.2
  • 38
    • 34547134744 scopus 로고    scopus 로고
    • Characterization of Agrobacterium tumefaciens DNA ligases C and D
    • Zhu, H. and Shuman, S. 2007. Characterization of Agrobacterium tumefaciens DNA ligases C and D. Nucleic Acids Res. 35: 3631-3645.
    • (2007) Nucleic Acids Res , vol.35 , pp. 3631-3645
    • Zhu, H.1    Shuman, S.2
  • 39
    • 32444451295 scopus 로고    scopus 로고
    • Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
    • Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., and Shuman, S. 2006. Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D. Proc. Natl. Acad. Sci. 103: 1711-1716.
    • (2006) Proc. Natl. Acad. Sci , vol.103 , pp. 1711-1716
    • Zhu, H.1    Nandakumar, J.2    Aniukwu, J.3    Wang, L.K.4    Glickman, M.S.5    Lima, C.D.6    Shuman, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.