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Volumn 14, Issue 23, 2004, Pages 2096-2106

DNA breaks promote genomic instability by impeding proper chromosome segregation

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; GREEN FLUORESCENT PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RAD52 PROTEIN;

EID: 10344225665     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2004.10.051     Document Type: Article
Times cited : (136)

References (45)
  • 1
    • 0034733497 scopus 로고    scopus 로고
    • Tying up loose ends: Nonhomologous end-joining in Saccharomyces cerevisiae
    • Lewis L.K., Resnick M.A. Tying up loose ends. nonhomologous end-joining in Saccharomyces cerevisiae Mutat. Res. 451:2000;71-89
    • (2000) Mutat. Res. , vol.451 , pp. 71-89
    • Lewis, L.K.1    Resnick, M.A.2
  • 2
    • 0036261707 scopus 로고    scopus 로고
    • Sensing and repairing DNA double-strand breaks
    • Jackson S.P. Sensing and repairing DNA double-strand breaks. Carcinogenesis. 23:2002;687-696
    • (2002) Carcinogenesis , vol.23 , pp. 687-696
    • Jackson, S.P.1
  • 3
    • 0036900120 scopus 로고    scopus 로고
    • Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair
    • Symington L.S. Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol. Mol. Biol. Rev. 66:2002;630-670
    • (2002) Microbiol. Mol. Biol. Rev. , vol.66 , pp. 630-670
    • Symington, L.S.1
  • 4
    • 0041903834 scopus 로고    scopus 로고
    • In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination
    • Sugawara N., Wang X., Haber J.E. In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination. Mol. Cell. 12:2003;209-219
    • (2003) Mol. Cell , vol.12 , pp. 209-219
    • Sugawara, N.1    Wang, X.2    Haber, J.E.3
  • 5
    • 0042626553 scopus 로고    scopus 로고
    • Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast
    • Wolner B., van Komen S., Sung P., Peterson C.L. Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast. Mol. Cell. 12:2003;221-232
    • (2003) Mol. Cell , vol.12 , pp. 221-232
    • Wolner, B.1    Van Komen, S.2    Sung, P.3    Peterson, C.L.4
  • 6
    • 19344366752 scopus 로고    scopus 로고
    • Role of Saccharomyces Single-Stranded DNA-Binding Protein RPA in the Strand Invasion Step of Double-Strand Break Repair
    • Wang X., Haber J.E. Role of Saccharomyces Single-Stranded DNA-Binding Protein RPA in the Strand Invasion Step of Double-Strand Break Repair. PLoS Biol. 2:2004;E21
    • (2004) PLoS Biol , vol.2 , pp. 21
    • Wang, X.1    Haber, J.E.2
  • 7
    • 0032527973 scopus 로고    scopus 로고
    • Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes
    • Gasior S.L., Wong A.K., Kora Y., Shinohara A., Bishop D.K. Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes. Genes Dev. 12:1998;2208-2221
    • (1998) Genes Dev. , vol.12 , pp. 2208-2221
    • Gasior, S.L.1    Wong, A.K.2    Kora, Y.3    Shinohara, A.4    Bishop, D.K.5
  • 8
    • 0242468933 scopus 로고    scopus 로고
    • Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences
    • Ma J.L., Kim E.M., Haber J.E., Lee S.E. Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences. Mol. Cell. Biol. 23:2003;8820-8828
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8820-8828
    • Ma, J.L.1    Kim, E.M.2    Haber, J.E.3    Lee, S.E.4
  • 10
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery, and chromosome loss
    • Sandell L.L., Zakian V.A. Loss of a yeast telomere. arrest, recovery, and chromosome loss Cell. 75:1993;729-739
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 11
    • 0030885666 scopus 로고    scopus 로고
    • CDC5 and CKII control adaptation to the yeast DNA damage checkpoint
    • Toczyski D.P., Galgoczy D.J., Hartwell L.H. CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell. 90:1997;1097-1106
    • (1997) Cell , vol.90 , pp. 1097-1106
    • Toczyski, D.P.1    Galgoczy, D.J.2    Hartwell, L.H.3
  • 12
    • 0027140403 scopus 로고
    • New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats
    • Kramer K.M., Haber J.E. New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats. Genes Dev. 7:1993;2345-2356
    • (1993) Genes Dev. , vol.7 , pp. 2345-2356
    • Kramer, K.M.1    Haber, J.E.2
  • 13
    • 0029947714 scopus 로고    scopus 로고
    • Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication
    • Malkova A., Ivanov E.L., Haber J.E. Double-strand break repair in the absence of RAD51 in yeast. a possible role for break-induced DNA replication Proc. Natl. Acad. Sci. USA. 93:1996;7131-7136
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7131-7136
    • Malkova, A.1    Ivanov, E.L.2    Haber, J.E.3
  • 14
    • 0035131636 scopus 로고    scopus 로고
    • Checkpoint adaptation precedes spontaneous and damage-induced genomic instability in yeast
    • Galgoczy D.J., Toczyski D.P. Checkpoint adaptation precedes spontaneous and damage-induced genomic instability in yeast. Mol. Cell. Biol. 21:2001;1710-1718
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1710-1718
    • Galgoczy, D.J.1    Toczyski, D.P.2
  • 15
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
    • Melo J.A., Cohen J., Toczyski D.P. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev. 15:2001;2809-2821
    • (2001) Genes Dev. , vol.15 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 16
    • 1642275935 scopus 로고    scopus 로고
    • Cell cycle-regulated centers of DNA double-strand break repair
    • Lisby M., De Mayolo A.A., Mortensen U.H., Rothstein R. Cell cycle-regulated centers of DNA double-strand break repair. Cell Cycle. 2:2003;479-483
    • (2003) Cell Cycle , vol.2 , pp. 479-483
    • Lisby, M.1    De Mayolo, A.A.2    Mortensen, U.H.3    Rothstein, R.4
  • 17
    • 0035955398 scopus 로고    scopus 로고
    • Recruitment of mec1 and ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms
    • Kondo T., Wakayama T., Naiki T., Matsumoto K., Sugimoto K. Recruitment of mec1 and ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science. 294:2001;867-870
    • (2001) Science , vol.294 , pp. 867-870
    • Kondo, T.1    Wakayama, T.2    Naiki, T.3    Matsumoto, K.4    Sugimoto, K.5
  • 18
    • 0030847538 scopus 로고    scopus 로고
    • Mitosis in living budding yeast: Anaphase a but no metaphase plate
    • Straight A.F., Marshall W.F., Sedat J.W., Murray A.W. Mitosis in living budding yeast. anaphase A but no metaphase plate Science. 277:1997;574-578
    • (1997) Science , vol.277 , pp. 574-578
    • Straight, A.F.1    Marshall, W.F.2    Sedat, J.W.3    Murray, A.W.4
  • 19
    • 0026583875 scopus 로고
    • Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated
    • Fishman-Lobell J., Rudin N., Haber J.E. Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Mol. Cell. Biol. 12:1992;1292-1303
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1292-1303
    • Fishman-Lobell, J.1    Rudin, N.2    Haber, J.E.3
  • 20
    • 0027158083 scopus 로고
    • Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast
    • Surana U., Amon A., Dowzer C., McGrew J., Byers B., Nasmyth K. Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J. 12:1993;1969-1978
    • (1993) EMBO J. , vol.12 , pp. 1969-1978
    • Surana, U.1    Amon, A.2    Dowzer, C.3    McGrew, J.4    Byers, B.5    Nasmyth, K.6
  • 21
    • 0020606021 scopus 로고
    • Pedigree analysis of plasmid segregation in yeast
    • Murray A.W., Szostak J.W. Pedigree analysis of plasmid segregation in yeast. Cell. 34:1983;961-970
    • (1983) Cell , vol.34 , pp. 961-970
    • Murray, A.W.1    Szostak, J.W.2
  • 22
    • 0028822203 scopus 로고
    • Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
    • Garvik B., Carson M., Hartwell L. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol. Cell. Biol. 15:1995;6128-6138
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6128-6138
    • Garvik, B.1    Carson, M.2    Hartwell, L.3
  • 23
    • 0023813873 scopus 로고
    • Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences
    • Rudin N., Haber J.E. Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. Mol. Biol. Cell. 8:1988;3918-3928
    • (1988) Mol. Biol. Cell , vol.8 , pp. 3918-3928
    • Rudin, N.1    Haber, J.E.2
  • 24
    • 0024292665 scopus 로고
    • Intra-chromosomal gene conversion induced by a DNA double-strand break in Saccharomyces cerevisiae
    • Ray A., Siddiqi I., Kolodkin A.L., Stahl F.W. Intra-chromosomal gene conversion induced by a DNA double-strand break in Saccharomyces cerevisiae. J. Mol. Biol. 201:1988;247-260
    • (1988) J. Mol. Biol. , vol.201 , pp. 247-260
    • Ray, A.1    Siddiqi, I.2    Kolodkin, A.L.3    Stahl, F.W.4
  • 25
  • 26
    • 0030760609 scopus 로고    scopus 로고
    • Break copy duplication: A model for chromosome fragment formation in Saccharomyces cerevisiae
    • Morrow D.M., Connelly C., Hieter P. Break copy duplication. A model for chromosome fragment formation in Saccharomyces cerevisiae Genetics. 147:1997;371-382
    • (1997) Genetics , vol.147 , pp. 371-382
    • Morrow, D.M.1    Connelly, C.2    Hieter, P.3
  • 27
    • 0000075523 scopus 로고
    • The behavior in successive nuclear divisions of a chromosome broken at meiosis
    • McClintock B. The behavior in successive nuclear divisions of a chromosome broken at meiosis. Proc. Natl. Acad. Sci. USA. 25:1939;405-416
    • (1939) Proc. Natl. Acad. Sci. USA , vol.25 , pp. 405-416
    • McClintock, B.1
  • 28
    • 0035989348 scopus 로고    scopus 로고
    • Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes
    • Craven R.J., Greenwell P.W., Dominska M., Petes T.D. Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. Genetics. 161:2002;493-507
    • (2002) Genetics , vol.161 , pp. 493-507
    • Craven, R.J.1    Greenwell, P.W.2    Dominska, M.3    Petes, T.D.4
  • 29
    • 0033771080 scopus 로고    scopus 로고
    • Telomere sequences at the novel joints of four independent amplifications in Saccharomyces cerevisiae
    • Moore I.K., Martin M.P., Paquin C.E. Telomere sequences at the novel joints of four independent amplifications in Saccharomyces cerevisiae. Environ. Mol. Mutagen. 36:2000;105-112
    • (2000) Environ. Mol. Mutagen. , vol.36 , pp. 105-112
    • Moore, I.K.1    Martin, M.P.2    Paquin, C.E.3
  • 30
    • 0032860479 scopus 로고    scopus 로고
    • Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
    • Chen C., Kolodner R.D. Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat. Genet. 23:1999;81-85
    • (1999) Nat. Genet. , vol.23 , pp. 81-85
    • Chen, C.1    Kolodner, R.D.2
  • 31
    • 0032518680 scopus 로고    scopus 로고
    • Ku protein stimulates DNA end joining by mammalian DNA ligases: A direct role for Ku in repair of DNA double-strand breaks
    • Ramsden D.A., Gellert M. Ku protein stimulates DNA end joining by mammalian DNA ligases. a direct role for Ku in repair of DNA double-strand breaks EMBO J. 17:1998;609-614
    • (1998) EMBO J. , vol.17 , pp. 609-614
    • Ramsden, D.A.1    Gellert, M.2
  • 32
    • 0037124373 scopus 로고    scopus 로고
    • Synapsis of DNA ends by DNA-dependent protein kinase
    • DeFazio L.G., Stansel R.M., Griffith J.D., Chu G. Synapsis of DNA ends by DNA-dependent protein kinase. EMBO J. 21:2002;3192-3200
    • (2002) EMBO J. , vol.21 , pp. 3192-3200
    • Defazio, L.G.1    Stansel, R.M.2    Griffith, J.D.3    Chu, G.4
  • 33
    • 0037109113 scopus 로고    scopus 로고
    • DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP
    • de Jager M., Wyman C., van Gent D.C., Kanaar R. DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP. Nucleic Acids Res. 30:2002;4425-4431
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4425-4431
    • De Jager, M.1    Wyman, C.2    Van Gent, D.C.3    Kanaar, R.4
  • 34
    • 0033594407 scopus 로고    scopus 로고
    • Binding of double-strand breaks in DNA by human Rad52 protein
    • Van Dyck E., Stasiak A.Z., Stasiak A., West S.C. Binding of double-strand breaks in DNA by human Rad52 protein. Nature. 398:1999;728-731
    • (1999) Nature , vol.398 , pp. 728-731
    • Van Dyck, E.1    Stasiak, A.Z.2    Stasiak, A.3    West, S.C.4
  • 35
    • 0035930342 scopus 로고    scopus 로고
    • Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes
    • Chen L., Trujillo K., Ramos W., Sung P., Tomkinson A.E. Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol. Cell. 8:2001;1105-1115
    • (2001) Mol. Cell , vol.8 , pp. 1105-1115
    • Chen, L.1    Trujillo, K.2    Ramos, W.3    Sung, P.4    Tomkinson, A.E.5
  • 36
    • 0038141976 scopus 로고    scopus 로고
    • Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre
    • Lisby M., Mortensen U.H., Rothstein R. Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre. Nat. Cell Biol. 5:2003;572-577
    • (2003) Nat. Cell Biol. , vol.5 , pp. 572-577
    • Lisby, M.1    Mortensen, U.H.2    Rothstein, R.3
  • 37
    • 0037178719 scopus 로고    scopus 로고
    • Segregating sister genomes: The molecular biology of chromosome separation
    • Nasmyth K. Segregating sister genomes. the molecular biology of chromosome separation Science. 297:2002;559-565
    • (2002) Science , vol.297 , pp. 559-565
    • Nasmyth, K.1
  • 38
    • 0036500690 scopus 로고    scopus 로고
    • SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
    • Yazdi P.T., Wang Y., Zhao S., Patel N., Lee E.Y., Qin J. SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev. 16:2002;571-582
    • (2002) Genes Dev. , vol.16 , pp. 571-582
    • Yazdi, P.T.1    Wang, Y.2    Zhao, S.3    Patel, N.4    Lee, E.Y.5    Qin, J.6
  • 39
    • 0036500555 scopus 로고    scopus 로고
    • Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
    • Kim S.T., Xu B., Kastan M.B. Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev. 16:2002;560-570
    • (2002) Genes Dev. , vol.16 , pp. 560-570
    • Kim, S.T.1    Xu, B.2    Kastan, M.B.3
  • 40
    • 0029928702 scopus 로고    scopus 로고
    • The force for poleward chromosome motion in Haemanthus cells acts along the length of the chromosome during metaphase but only at the kinetochore during anaphase
    • Khodjakov A., Cole R.W., Bajer A.S., Rieder C.L. The force for poleward chromosome motion in Haemanthus cells acts along the length of the chromosome during metaphase but only at the kinetochore during anaphase. J. Cell Biol. 132:1996;1093-1104
    • (1996) J. Cell Biol. , vol.132 , pp. 1093-1104
    • Khodjakov, A.1    Cole, R.W.2    Bajer, A.S.3    Rieder, C.L.4
  • 41
    • 0023659131 scopus 로고
    • The structure of sister minichromosome DNA before anaphase in Saccharomyces cerevisiae
    • Koshland D., Hartwell L.H. The structure of sister minichromosome DNA before anaphase in Saccharomyces cerevisiae. Science. 238:1987;1713-1716
    • (1987) Science , vol.238 , pp. 1713-1716
    • Koshland, D.1    Hartwell, L.H.2
  • 42
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel B., Smogorzewska A., de Lange T. TRF2 protects human telomeres from end-to-end fusions. Cell. 92:1998;401-413
    • (1998) Cell , vol.92 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 43
    • 0343384126 scopus 로고    scopus 로고
    • Activating the DNA damage checkpoint in a developmental context
    • Su T.T., Walker J., Stumpff J. Activating the DNA damage checkpoint in a developmental context. Curr. Biol. 10:2000;119-126
    • (2000) Curr. Biol. , vol.10 , pp. 119-126
    • Su, T.T.1    Walker, J.2    Stumpff, J.3
  • 44
    • 10344224464 scopus 로고
    • Some effects of X-radiation on the neuroblast chromosomes of the grasshopper, Chortophaga viridifasciata
    • Carlson J.G. Some effects of X-radiation on the neuroblast chromosomes of the grasshopper, Chortophaga viridifasciata. Genetics. 23:1938;596-609
    • (1938) Genetics. , vol.23 , pp. 596-609
    • Carlson, J.G.1
  • 45
    • 0034632717 scopus 로고    scopus 로고
    • Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    • Artandi S.E., Chang S., Lee S.L., Alson S., Gottlieb G.J., Chin L., DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature. 406:2000;641-645
    • (2000) Nature , vol.406 , pp. 641-645
    • Artandi, S.E.1    Chang, S.2    Lee, S.L.3    Alson, S.4    Gottlieb, G.J.5    Chin, L.6    Depinho, R.A.7


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