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Volumn 27, Issue 13, 2008, Pages 1875-1885

Break dosage, cell cycle stage and DNA replication influence DNA double strand break response

Author keywords

Cell cycle; Checkpoints; DNA damage; DNA replication

Indexed keywords

DOUBLE STRANDED DNA; ENDONUCLEASE; SINGLE STRANDED DNA;

EID: 46949098616     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.111     Document Type: Article
Times cited : (190)

References (57)
  • 3
    • 0037317683 scopus 로고    scopus 로고
    • Molecular dissection of mitotic recombination in the yeast Saccharomyces cerevisiae
    • Aylon Y, Liefshitz B, Bitan-Banin G, Kupiec M (2003) Molecular dissection of mitotic recombination in the yeast Saccharomyces cerevisiae. Mol Cell Biol 23: 1403-1417
    • (2003) Mol Cell Biol , vol.23 , pp. 1403-1417
    • Aylon, Y.1    Liefshitz, B.2    Bitan-Banin, G.3    Kupiec, M.4
  • 4
    • 11244269445 scopus 로고    scopus 로고
    • The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
    • Aylon Y, Liefshitz B, Kupiec M (2004) The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J 23: 4868-4875
    • (2004) EMBO J , vol.23 , pp. 4868-4875
    • Aylon, Y.1    Liefshitz, B.2    Kupiec, M.3
  • 5
    • 39549114009 scopus 로고    scopus 로고
    • Differential regulation of the cellular response to DNA double-strand breaks in G1
    • Barlow JH, Lisby M, Rothstein R (2008) Differential regulation of the cellular response to DNA double-strand breaks in G1. Mol Cell 30: 73-85
    • (2008) Mol Cell , vol.30 , pp. 73-85
    • Barlow, J.H.1    Lisby, M.2    Rothstein, R.3
  • 6
    • 0035504409 scopus 로고    scopus 로고
    • Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction
    • Booth C, Griffith E, Brady G, Lydall D (2001) Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction. Nucleic Acids Res 29: 4414-4422
    • (2001) Nucleic Acids Res , vol.29 , pp. 4414-4422
    • Booth, C.1    Griffith, E.2    Brady, G.3    Lydall, D.4
  • 7
    • 0036276388 scopus 로고    scopus 로고
    • The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
    • D'Amours D, Jackson SP (2002) The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nat Rev Mol Cell Biol 3: 317-327
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 317-327
    • D'Amours, D.1    Jackson, S.P.2
  • 9
    • 12844278880 scopus 로고    scopus 로고
    • Rejoining of DNA double-strand breaks as a function of overhang length
    • Daley JM, Wilson TE (2005) Rejoining of DNA double-strand breaks as a function of overhang length. Mol Cell Biol 25: 896-906
    • (2005) Mol Cell Biol , vol.25 , pp. 896-906
    • Daley, J.M.1    Wilson, T.E.2
  • 10
    • 0034807715 scopus 로고    scopus 로고
    • Cell cycle arrest determines the intensity of the global transcriptional response of Saccharomyces cerevisiae to ionizing radiation
    • De Sanctis V, Bertozzi C, Costanzo G, Di Mauro E, Negri R (2001) Cell cycle arrest determines the intensity of the global transcriptional response of Saccharomyces cerevisiae to ionizing radiation. Radiat Res 156: 379-387
    • (2001) Radiat Res , vol.156 , pp. 379-387
    • De Sanctis, V.1    Bertozzi, C.2    Costanzo, G.3    Di Mauro, E.4    Negri, R.5
  • 12
    • 0028098812 scopus 로고
    • Two steps in the assembly of complexes at yeast replication origins in vivo
    • Diffley JF, Cocker JH, Dowell SJ, Rowley A (1994) Two steps in the assembly of complexes at yeast replication origins in vivo. Cell 78: 303-316
    • (1994) Cell , vol.78 , pp. 303-316
    • Diffley, J.F.1    Cocker, J.H.2    Dowell, S.J.3    Rowley, A.4
  • 13
    • 0026583875 scopus 로고
    • Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated
    • Fishman-Lobell J, Rudin N, Haber JE (1992) Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Mol Cell Biol 12: 1292-1303
    • (1992) Mol Cell Biol , vol.12 , pp. 1292-1303
    • Fishman-Lobell, J.1    Rudin, N.2    Haber, J.E.3
  • 14
    • 0036864626 scopus 로고    scopus 로고
    • Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
    • Frank-Vaillant M, Marcand S (2002) Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination. Mol Cell 10: 1189-1199
    • (2002) Mol Cell , vol.10 , pp. 1189-1199
    • Frank-Vaillant, M.1    Marcand, S.2
  • 15
    • 0028822203 scopus 로고
    • Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
    • Garvik B, Carson M, Hartwell L (1995) Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol Cell Biol 15: 6128-6138
    • (1995) Mol Cell Biol , vol.15 , pp. 6128-6138
    • Garvik, B.1    Carson, M.2    Hartwell, L.3
  • 17
    • 0032412476 scopus 로고    scopus 로고
    • Mating-type gene switching in Saccharomyces cerevisiae
    • Haber JE (1998) Mating-type gene switching in Saccharomyces cerevisiae. Annu Rev Genet 32: 561-599
    • (1998) Annu Rev Genet , vol.32 , pp. 561-599
    • Haber, J.E.1
  • 18
    • 0036277140 scopus 로고    scopus 로고
    • Uses and abuses of HO endonuclease
    • Haber JE (2002) Uses and abuses of HO endonuclease. Methods Enzymol 350: 141-164
    • (2002) Methods Enzymol , vol.350 , pp. 141-164
    • Haber, J.E.1
  • 20
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers JH (2001) Genome maintenance mechanisms for preventing cancer. Nature 411: 366-374
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 24
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • Lee SE, Moore JK, Holmes A, Umezu K, Kolodner RD, Haber JE (1998) Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94: 399-409
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.D.5    Haber, J.E.6
  • 25
    • 36248942617 scopus 로고    scopus 로고
    • Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
    • Lengsfeld BM, Rattray AJ, Bhaskara V, Ghirlando R, Paull TT (2007) Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Mol Cell 28: 638-651
    • (2007) Mol Cell , vol.28 , pp. 638-651
    • Lengsfeld, B.M.1    Rattray, A.J.2    Bhaskara, V.3    Ghirlando, R.4    Paull, T.T.5
  • 26
    • 0031455421 scopus 로고    scopus 로고
    • Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants
    • Liang C, Stillman B (1997) Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants. Genes Dev 11: 3375-3386
    • (1997) Genes Dev , vol.11 , pp. 3375-3386
    • Liang, C.1    Stillman, B.2
  • 28
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
    • Lisby M, Barlow JH, Burgess RC, Rothstein R (2004) Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins. Cell 118: 699-713
    • (2004) Cell , vol.118 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 29
    • 0035902544 scopus 로고    scopus 로고
    • Rad52 forms DNA repair and recombination centers during S phase
    • Lisby M, Rothstein R, Mortensen UH (2001) Rad52 forms DNA repair and recombination centers during S phase. Proc Natl Acad Sci USA 98: 8276-8282
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8276-8282
    • Lisby, M.1    Rothstein, R.2    Mortensen, U.H.3
  • 30
    • 6344254299 scopus 로고    scopus 로고
    • The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks
    • Llorente B, Symington LS (2004) The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks. Mol Cell Biol 24: 9682-9694
    • (2004) Mol Cell Biol , vol.24 , pp. 9682-9694
    • Llorente, B.1    Symington, L.S.2
  • 31
    • 0344413642 scopus 로고    scopus 로고
    • The S-phase checkpoint and its regulation in Saccharomyces cerevisiae
    • Longhese MP, Clerici M, Lucchini G (2003) The S-phase checkpoint and its regulation in Saccharomyces cerevisiae. Mutat Res 532: 41-58
    • (2003) Mutat Res , vol.532 , pp. 41-58
    • Longhese, M.P.1    Clerici, M.2    Lucchini, G.3
  • 32
    • 33745245557 scopus 로고    scopus 로고
    • The cellular response to chromosome breakage
    • Longhese MP, Mantiero D, Clerici M (2006) The cellular response to chromosome breakage. Mol Microbiol 60: 1099-1108
    • (2006) Mol Microbiol , vol.60 , pp. 1099-1108
    • Longhese, M.P.1    Mantiero, D.2    Clerici, M.3
  • 33
    • 22444448143 scopus 로고    scopus 로고
    • A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response
    • Masumoto H, Hawke D, Kobayashi R, Verreault A (2005) A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response. Nature 436: 294-298
    • (2005) Nature , vol.436 , pp. 294-298
    • Masumoto, H.1    Hawke, D.2    Kobayashi, R.3    Verreault, A.4
  • 34
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
    • Melo JA, Cohen J, Toczyski DP (2001) Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev 15: 2809-2821
    • (2001) Genes Dev , vol.15 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 35
    • 0030271945 scopus 로고    scopus 로고
    • At the heart of the budding yeast cell cycle
    • Nasmyth K (1996) At the heart of the budding yeast cell cycle. Trends Genet 12: 405-412
    • (1996) Trends Genet , vol.12 , pp. 405-412
    • Nasmyth, K.1
  • 36
    • 14044258346 scopus 로고    scopus 로고
    • G2 damage checkpoints: What is the turn-on?
    • O'Connell MJ, Cimprich KA (2005) G2 damage checkpoints: what is the turn-on? J Cell Sci 118: 1-6
    • (2005) J Cell Sci , vol.118 , pp. 1-6
    • O'Connell, M.J.1    Cimprich, K.A.2
  • 37
    • 0034663809 scopus 로고    scopus 로고
    • The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
    • Paciotti V, Clerici M, Lucchini G, Longhese MP (2000) The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. Genes Dev 14: 2046-2059
    • (2000) Genes Dev , vol.14 , pp. 2046-2059
    • Paciotti, V.1    Clerici, M.2    Lucchini, G.3    Longhese, M.P.4
  • 38
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Paques F, Haber JE (1999) Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 63: 349-404
    • (1999) Microbiol Mol Biol Rev , vol.63 , pp. 349-404
    • Paques, F.1    Haber, J.E.2
  • 39
    • 0035105240 scopus 로고    scopus 로고
    • Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest
    • Pellicioli A, Lee SE, Lucca C, Foiani M, Haber JE (2001) Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. Mol Cell 7: 293-300
    • (2001) Mol Cell , vol.7 , pp. 293-300
    • Pellicioli, A.1    Lee, S.E.2    Lucca, C.3    Foiani, M.4    Haber, J.E.5
  • 40
    • 0033570894 scopus 로고    scopus 로고
    • Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
    • Pellicioli A, Lucca C, Liberi G, Marini F, Lopes M, Plevani P, Romano A, Di Fiore PP, Foiani M (1999) Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. EMBO J 18: 6561-6572
    • (1999) EMBO J , vol.18 , pp. 6561-6572
    • Pellicioli, A.1    Lucca, C.2    Liberi, G.3    Marini, F.4    Lopes, M.5    Plevani, P.6    Romano, A.7    Di Fiore, P.P.8    Foiani, M.9
  • 41
    • 0029082391 scopus 로고
    • Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae
    • Piatti S, Lengauer C, Nasmyth K (1995) Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae. EMBO J 14: 3788-3799
    • (1995) EMBO J , vol.14 , pp. 3788-3799
    • Piatti, S.1    Lengauer, C.2    Nasmyth, K.3
  • 42
    • 0034329474 scopus 로고    scopus 로고
    • LCD1: An essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae
    • Rouse J, Jackson SP (2000) LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae. EMBO J 19: 5801-5812
    • (2000) EMBO J , vol.19 , pp. 5801-5812
    • Rouse, J.1    Jackson, S.P.2
  • 43
    • 0037178748 scopus 로고    scopus 로고
    • Interfaces between the detection, signaling, and repair of DNA damage
    • Rouse J, Jackson SP (2002) Interfaces between the detection, signaling, and repair of DNA damage. Science 297: 547-551
    • (2002) Science , vol.297 , pp. 547-551
    • Rouse, J.1    Jackson, S.P.2
  • 44
    • 0030749258 scopus 로고    scopus 로고
    • A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks
    • Schar P, Herrmann G, Daly G, Lindahl T (1997) A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks. Genes Dev 11: 1912-1924
    • (1997) Genes Dev , vol.11 , pp. 1912-1924
    • Schar, P.1    Herrmann, G.2    Daly, G.3    Lindahl, T.4
  • 45
    • 0033582544 scopus 로고    scopus 로고
    • Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin
    • Shibahara K, Stillman B (1999) Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. Cell 96: 575-585
    • (1999) Cell , vol.96 , pp. 575-585
    • Shibahara, K.1    Stillman, B.2
  • 46
    • 0035908913 scopus 로고    scopus 로고
    • Lack of tension at kinetochores activates the spindle checkpoint in budding yeast
    • Stern BM, Murray AW (2001) Lack of tension at kinetochores activates the spindle checkpoint in budding yeast. Curr Biol 11: 1462-1467
    • (2001) Curr Biol , vol.11 , pp. 1462-1467
    • Stern, B.M.1    Murray, A.W.2
  • 47
    • 0030849085 scopus 로고    scopus 로고
    • Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
    • Teo SH, Jackson SP (1997) Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J 16: 4788-4795
    • (1997) EMBO J , vol.16 , pp. 4788-4795
    • Teo, S.H.1    Jackson, S.P.2
  • 48
    • 0034595211 scopus 로고    scopus 로고
    • DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p
    • Tercero JA, Labib K, Diffley JF (2000) DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p. EMBO J 19: 2082-2093
    • (2000) EMBO J , vol.19 , pp. 2082-2093
    • Tercero, J.A.1    Labib, K.2    Diffley, J.F.3
  • 49
    • 0038730929 scopus 로고    scopus 로고
    • A central role for DNA replication forks in checkpoint activation and response
    • Tercero JA, Longhese MP, Diffley JF (2003) A central role for DNA replication forks in checkpoint activation and response. Mol Cell 11: 1323-1336
    • (2003) Mol Cell , vol.11 , pp. 1323-1336
    • Tercero, J.A.1    Longhese, M.P.2    Diffley, J.F.3
  • 50
    • 0032497566 scopus 로고    scopus 로고
    • Cohesion between sister chromatids must be established during DNA replication
    • Uhlmann F, Nasmyth K (1998) Cohesion between sister chromatids must be established during DNA replication. Curr Biol 8: 1095-1101
    • (1998) Curr Biol , vol.8 , pp. 1095-1101
    • Uhlmann, F.1    Nasmyth, K.2
  • 52
    • 0033582262 scopus 로고    scopus 로고
    • The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin
    • Weinreich M, Liang C, Stillman B (1999) The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin. Proc Natl Acad Sci USA 96: 441-446
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 441-446
    • Weinreich, M.1    Liang, C.2    Stillman, B.3
  • 53
    • 0025020278 scopus 로고
    • Intermediates of recombination during mating type switching in Saccharomyces cerevisiae
    • White CI, Haber JE (1990) Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J 9: 663-673
    • (1990) EMBO J , vol.9 , pp. 663-673
    • White, C.I.1    Haber, J.E.2
  • 54
    • 36148937572 scopus 로고    scopus 로고
    • RecBCD: The supercar of DNA repair
    • Wigley DB (2007) RecBCD: the supercar of DNA repair. Cell 131: 651-653
    • (2007) Cell , vol.131 , pp. 651-653
    • Wigley, D.B.1
  • 55
    • 0030811523 scopus 로고    scopus 로고
    • Yeast DNA ligase IV mediates non-homologous DNA end joining
    • Wilson TE, Grawunder U, Lieber MR (1997) Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature 388: 495-498
    • (1997) Nature , vol.388 , pp. 495-498
    • Wilson, T.E.1    Grawunder, U.2    Lieber, M.R.3
  • 56
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L, Elledge SJ (2003) Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300: 1542-1548
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 57
    • 33745199615 scopus 로고    scopus 로고
    • Detecting repair intermediates in vivo: Effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast
    • Zubko MK, Maringele L, Foster SS, Lydall D (2006) Detecting repair intermediates in vivo: effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast. Methods Enzymol 409: 285-300
    • (2006) Methods Enzymol , vol.409 , pp. 285-300
    • Zubko, M.K.1    Maringele, L.2    Foster, S.S.3    Lydall, D.4


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